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TAAR1

Index TAAR1

Trace amine-associated receptor 1 (TAAR1) is a trace amine-associated receptor (TAAR) protein that in humans is encoded by the TAAR1 gene. [1]

161 relations: Action potential, Adenylyl cyclase, Agonist, Alpha-2 adrenergic receptor, Alpha-2A adrenergic receptor, Amine, Amino acid, Amphetamine, Astrocyte, Attention deficit hyperactivity disorder, Autoreceptor, Axon terminal, B cell, Benzofuran, Beta cell, Bioavailability, Brain, C-terminus, Cardiac output, Catecholamine, Caudate nucleus, Cell (biology), Cell membrane, Central nervous system, Ceteris paribus, Chemical synapse, Chimpanzee, Chromosome, Chromosome 6, Complementary DNA, Cyclic adenosine monophosphate, Cytoplasm, Delta cell, Diabetes mellitus, DNA, Dopamine, Dopamine receptor D2, Dopamine transporter, Duodenum, Endocrine system, Endocytosis, Endogeny (biology), EPPTB, Evolution, Exogeny, Exon, Förster resonance energy transfer, G protein, G protein-coupled inwardly-rectifying potassium channel, G protein–coupled receptor, ..., Gastrointestinal tract, Gene, Genome, Glucagon-like peptide-1, GPCR oligomer, Gq alpha subunit, Granulocyte, Gs alpha subunit, GSK-3, Homology (biology), Hormone, Human, Immune system, Immunoglobulin E, In vivo, Insulin, Interleukin 4, Intron, Kidney, Ligand, Ligand (biochemistry), Locus coeruleus, Lung, Lysergic acid diethylamide, Major depressive disorder, Mammal, MDMA, Membrane transport protein, Messenger RNA, Meta-Tyramine, Metabolism, Methamphetamine, Methylphenethylamine, Monkey, Monoamine neurotransmitter, Monoamine oxidase, Mouse, Mutation, N-Methylphenethylamine, N-Methyltyramine, N-terminus, Nervous system, Neuroimmune system, Neuron, Neurotransmission, NFAT, Norepinephrine, Norepinephrine transporter, Norfenefrine, Nucleic acid sequence, Nucleus accumbens, Obesity, Octopamine (neurotransmitter), Olfactory epithelium, Oligonucleotide, Peptide, Peptide YY, Phenethylamine, Phosphorylation, Phytohaemagglutinin, Protein, Protein dimer, Protein family, Protein kinase A, Protein kinase B, Protein kinase C, Protein subfamily, Putamen, Raphe nuclei, Rat, Reuptake inhibitor, Reverse transport, Rhesus macaque, Rhodopsin-like receptors, RO5166017, Schizophrenia, Sequence motif, Serotonin, Serotonin transporter, Signal transduction, SLC1A2, Small intestine, Somatostatin, Species, Stomach, Substantia nigra, Sympathetic nervous system, Synephrine, T cell, TAAR2, Thermoregulation, Thyroid, Thyronamine, Trace amine, Trace amine-associated receptor, Transmembrane domain, Tryptamine, Tyramine, Ventral tegmental area, White blood cell, 2-Methylphenethylamine, 2C-B-FLY, 3-Iodothyronamine, 3-Methylphenethylamine, 4-Methylphenethylamine, 5-APB, 5-APDB, 5-EAPB, 5-MAPDB, 6-APB, 6-APDB. Expand index (111 more) »

Action potential

In physiology, an action potential occurs when the membrane potential of a specific axon location rapidly rises and falls: this depolarisation then causes adjacent locations to similarly depolarise.

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Adenylyl cyclase

Adenylyl cyclase (also commonly known as adenyl cyclase and adenylate cyclase, abbreviated AC) is an enzyme with key regulatory roles in essentially all cells.

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Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Alpha-2 adrenergic receptor

The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein.

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Alpha-2A adrenergic receptor

The alpha-2A adrenergic receptor (α2A adrenoceptor), also known as ADRA2A, is an α2 adrenergic receptor, and also denotes the human gene encoding it.

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Amine

In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair.

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Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

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Amphetamine

Amphetamine (contracted from) is a potent central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity.

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Astrocyte

Astrocytes (Astro from Greek astron.

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Attention deficit hyperactivity disorder

Attention-deficit hyperactivity disorder (ADHD) is a mental disorder of the neurodevelopmental type.

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Autoreceptor

An autoreceptor is a type of receptor located in the membranes of presynaptic nerve cells.

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Axon terminal

Axon terminals (also called synaptic boutons or terminal boutons) are distal terminations of the telodendria (branches) of an axon.

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B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.

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Benzofuran

Benzofuran is the heterocyclic compound consisting of fused benzene and furan rings.

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Beta cell

Beta cells (β cells) are a type of cell found in the pancreatic islets of the pancreas.

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Bioavailability

In pharmacology, bioavailability (BA or F) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.

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Brain

The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.

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C-terminus

The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

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Cardiac output

Cardiac output (CO, also denoted by the symbols Q and \dot Q_), is a term used in cardiac physiology that describes the volume of blood being pumped by the heart, in particular by the left or right ventricle, per unit time.

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Catecholamine

A catecholamine (CA) is a monoamine, an organic compound that has a catechol (benzene with two hydroxyl side groups at carbons 1 and 2) and a side-chain amine.

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Caudate nucleus

The caudate nucleus is one of the structures that make up the dorsal striatum, which is a component of the basal ganglia.

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Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Ceteris paribus

Ceteris paribus or caeteris paribus is a Latin phrase meaning "other things equal".

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Chemical synapse

Chemical synapses are biological junctions through which neurons' signals can be exchanged to each other and to non-neuronal cells such as those in muscles or glands.

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Chimpanzee

The taxonomical genus Pan (often referred to as chimpanzees or chimps) consists of two extant species: the common chimpanzee and the bonobo.

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Chromosome

A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.

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Chromosome 6

Chromosome 6 is one of the 23 pairs of chromosomes in humans.

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Complementary DNA

In genetics, complementary DNA (cDNA) is DNA synthesized from a single stranded RNA (e.g., messenger RNA (mRNA) or microRNA) template in a reaction catalyzed by the enzyme reverse transcriptase.

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Cyclic adenosine monophosphate

Cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine monophosphate) is a second messenger important in many biological processes.

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Cytoplasm

In cell biology, the cytoplasm is the material within a living cell, excluding the cell nucleus.

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Delta cell

Delta cells (δ-cells or D cells) are somatostatin-producing cells.

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Diabetes mellitus

Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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Dopamine

Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.

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Dopamine receptor D2

Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene.

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Dopamine transporter

The dopamine transporter (also dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synaptic cleft back into cytosol.

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Duodenum

The duodenum is the first section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds.

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Endocrine system

The endocrine system is a chemical messenger system consisting of hormones, the group of glands of an organism that carry those hormones directly into the circulatory system to be carried towards distant target organs, and the feedback loops of homeostasis that the hormones drive.

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Endocytosis

Endocytosis is a form of bulk transport in which a cell transports molecules (such as proteins) into the cell (endo- + cytosis) by engulfing them in an energy-using process.

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Endogeny (biology)

Endogenous substances and processes are those that originate from within an organism, tissue, or cell.

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EPPTB

EPPTB (RO-5212773) is a drug developed by Hoffmann-La Roche which acts as a potent and selective inverse agonist of trace amine-associated receptor 1 (TAAR1), with no significant activity at other targets.

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Evolution

Evolution is change in the heritable characteristics of biological populations over successive generations.

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Exogeny

In a variety of contexts, exogeny or exogeneity is the fact of an action or object originating externally.

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Exon

An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.

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Förster resonance energy transfer

Förster resonance energy transfer (FRET), fluorescence resonance energy transfer (FRET), resonance energy transfer (RET) or electronic energy transfer (EET) is a mechanism describing energy transfer between two light-sensitive molecules (chromophores).

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G protein

G proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli outside a cell to its interior.

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G protein-coupled inwardly-rectifying potassium channel

The G protein-coupled inwardly-rectifying potassium channels (GIRKs) are a family of inward-rectifier potassium ion channels which are activated (opened) via a signal transduction cascade starting with ligand-stimulated G protein-coupled receptors (GPCRs).

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G protein–coupled receptor

G protein–coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptor, and G protein–linked receptors (GPLR), constitute a large protein family of receptors that detect molecules outside the cell and activate internal signal transduction pathways and, ultimately, cellular responses.

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Gastrointestinal tract

The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Genome

In the fields of molecular biology and genetics, a genome is the genetic material of an organism.

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Glucagon-like peptide-1

Glucagon-like peptide-1 (GLP-1) is a 30 amino acid long peptide hormone deriving from the tissue-specific posttranslational processing of the proglucagon peptide.

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GPCR oligomer

A GPCR oligomer is a protein complex that consists of a small number (ὀλίγοι oligoi "a few", μέρος méros "part, piece, component") of G protein-coupled receptors (GPCRs).

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Gq alpha subunit

Gq protein (Gαq, or Gq/11) is a heterotrimeric G protein subunit that activates phospholipase C (PLC).

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Granulocyte

Granulocytes are a category of white blood cells characterized by the presence of granules in their cytoplasm.

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Gs alpha subunit

The Gs alpha subunit (Gαs, Gsα, or Gs protein) is a heterotrimeric G protein subunit that activates the cAMP-dependent pathway by activating adenylyl cyclase.

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GSK-3

Glycogen synthase kinase 3 is a serine/threonine protein kinase that mediates the addition of phosphate molecules onto serine and threonine amino acid residues.

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Homology (biology)

In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa.

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Hormone

A hormone (from the Greek participle “ὁρμῶ”, "to set in motion, urge on") is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour.

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Human

Humans (taxonomically Homo sapiens) are the only extant members of the subtribe Hominina.

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Immune system

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.

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Immunoglobulin E

Immunoglobulin E (IgE) is a type of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals.

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In vivo

Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.

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Insulin

Insulin (from Latin insula, island) is a peptide hormone produced by beta cells of the pancreatic islets; it is considered to be the main anabolic hormone of the body.

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Interleukin 4

The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells.

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Intron

An intron is any nucleotide sequence within a gene that is removed by RNA splicing during maturation of the final RNA product.

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Kidney

The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.

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Ligand

In coordination chemistry, a ligand is an ion or molecule (functional group) that binds to a central metal atom to form a coordination complex.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Locus coeruleus

The locus coeruleus (\-si-ˈrü-lē-əs\, also spelled locus caeruleus or locus ceruleus) is a nucleus in the pons of the brainstem involved with physiological responses to stress and panic.

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Lung

The lungs are the primary organs of the respiratory system in humans and many other animals including a few fish and some snails.

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Lysergic acid diethylamide

Lysergic acid diethylamide (LSD), also known as acid, is a psychedelic drug known for its psychological effects, which may include altered awareness of one's surroundings, perceptions, and feelings as well as sensations and images that seem real though they are not.

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Major depressive disorder

Major depressive disorder (MDD), also known simply as depression, is a mental disorder characterized by at least two weeks of low mood that is present across most situations.

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Mammal

Mammals are the vertebrates within the class Mammalia (from Latin mamma "breast"), a clade of endothermic amniotes distinguished from reptiles (including birds) by the possession of a neocortex (a region of the brain), hair, three middle ear bones, and mammary glands.

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MDMA

3,4-Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy (E), is a psychoactive drug used primarily as a recreational drug.

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Membrane transport protein

A membrane transport protein (or simply transporter) is a membrane protein involved in the movement of ions, small molecules, or macromolecules, such as another protein, across a biological membrane.

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Messenger RNA

Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.

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Meta-Tyramine

meta-Tyramine, also known as m-tyramine and 3-tyramine, is an endogenous trace amine neuromodulator and a structural analog of phenethylamine.

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Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.

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Methamphetamine

Methamphetamine (contracted from) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity.

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Methylphenethylamine

Methylphenethylamine may refer to.

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Monkey

Monkeys are non-hominoid simians, generally possessing tails and consisting of about 260 known living species.

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Monoamine neurotransmitter

Monoamine neurotransmitters are neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by a two-carbon chain (such as -CH2-CH2-). All monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes.

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Monoamine oxidase

L-Monoamine oxidases (MAO) are a family of enzymes that catalyze the oxidation of monoamines.

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Mouse

A mouse (Mus), plural mice, is a small rodent characteristically having a pointed snout, small rounded ears, a body-length scaly tail and a high breeding rate.

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Mutation

In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.

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N-Methylphenethylamine

N-Methylphenethylamine (NMPEA) is a naturally occurring trace amine neuromodulator in humans that is derived from the trace amine, phenethylamine (PEA).

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N-Methyltyramine

N-Methyltyramine (NMT), also known as 4-hydroxy-N-methylphenethylamine, is a human trace amine and natural phenethylamine alkaloid found in a variety of plants.

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N-terminus

The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.

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Nervous system

The nervous system is the part of an animal that coordinates its actions by transmitting signals to and from different parts of its body.

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Neuroimmune system

The neuroimmune system is a system of structures and processes involving the biochemical and electrophysiological interactions between the nervous system and immune system which protect neurons from pathogens.

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Neuron

A neuron, also known as a neurone (British spelling) and nerve cell, is an electrically excitable cell that receives, processes, and transmits information through electrical and chemical signals.

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Neurotransmission

Neurotransmission (Latin: transmissio "passage, crossing" from transmittere "send, let through"), also called synaptic transmission, is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), and bind to and activate the receptors on the dendrites of another neuron (the postsynaptic neuron).

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NFAT

Nuclear factor of activated T-cells (NFAT) is a family of transcription factors shown to be important in immune response.

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Norepinephrine

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.

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Norepinephrine transporter

The norepinephrine transporter (NET), also known as solute carrier family 6 member 2 (SLC6A2), is a protein that in humans is encoded by the SLC6A2 gene.

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Norfenefrine

Norfenefrine (INN) or meta-octopamine (3-octopamine), also known as 3,β-dihydroxyphenethylamine, is an adrenergic agent used as a sympathomimetic drug which is marketed in Europe, Japan, and Mexico.

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Nucleic acid sequence

A nucleic acid sequence is a succession of letters that indicate the order of nucleotides forming alleles within a DNA (using GACT) or RNA (GACU) molecule.

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Nucleus accumbens

The nucleus accumbens (NAc or NAcc), also known as the accumbens nucleus, or formerly as the nucleus accumbens septi (Latin for nucleus adjacent to the septum) is a region in the basal forebrain rostral to the preoptic area of the hypothalamus.

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Obesity

Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health.

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Octopamine (neurotransmitter)

Octopamine is an organic chemical closely related to norepinephrine, and synthesized biologically by a homologous pathway.

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Olfactory epithelium

The olfactory epithelium is a specialized epithelial tissue inside the nasal cavity that is involved in smell.

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Oligonucleotide

Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testing, research, and forensics.

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Peptide

Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.

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Peptide YY

Peptide YY (PYY) also known as peptide tyrosine tyrosine is a peptide that in humans is encoded by the PYY gene.

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Phenethylamine

Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine which acts as a central nervous system stimulant in humans.

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Phosphorylation

In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.

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Phytohaemagglutinin

Phytohaemagglutinin (PHA, or phytohemagglutinin) is a lectin found in plants, especially certain legumes.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein dimer

In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are usually non-covalently bound.

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Protein family

A protein family is a group of evolutionarily-related proteins.

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Protein kinase A

In cell biology, protein kinase A (PKANot to be confused with pKa, the symbol for the acid dissociation constant.) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP (cAMP).

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Protein kinase B

Protein kinase B (PKB), also known as Akt, is a serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription and cell migration.

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Protein kinase C

Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family.

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Protein subfamily

Protein subfamily is a level of protein classification, based on their close evolutionary relationship.

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Putamen

The putamen is a round structure located at the base of the forebrain (telencephalon).

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Raphe nuclei

The raphe nuclei (ῥαφή "seam"Liddell, H.G. & Scott, R. (1940). A Greek-English Lexicon. revised and augmented throughout by Sir Henry Stuart Jones. with the assistance of. Roderick McKenzie. Oxford: Clarendon Press.) are a moderate-size cluster of nuclei found in the brain stem.

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Rat

Rats are various medium-sized, long-tailed rodents in the superfamily Muroidea.

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Reuptake inhibitor

A reuptake inhibitor (RI) is a type of drug known as a reuptake modulator that inhibits the plasmalemmal transporter-mediated reuptake of a neurotransmitter from the synapse into the pre-synaptic neuron.

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Reverse transport

Reverse transport, or transporter reversal, is a phenomenon in which the substrates of a membrane transport protein are moved in the opposite direction to that of their typical movement by the transporter.

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Rhesus macaque

The rhesus macaque (Macaca mulatta) is one of the best-known species of Old World monkeys.

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Rhodopsin-like receptors

Rhodopsin-like receptors are a family of proteins that comprise the largest group of G protein-coupled receptors.

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RO5166017

RO-5166017 is a drug developed by Hoffmann-La Roche which acts as a potent and selective agonist for the trace amine-associated receptor 1, with no significant activity at other targets.

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Schizophrenia

Schizophrenia is a mental disorder characterized by abnormal social behavior and failure to understand reality.

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Sequence motif

In genetics, a sequence motif is a nucleotide or amino-acid sequence pattern that is widespread and has, or is conjectured to have, a biological significance.

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Serotonin

Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

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Serotonin transporter

The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene.

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Signal transduction

Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.

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SLC1A2

Excitatory amino acid transporter 2 (EAAT2) also known as solute carrier family 1 member 2 (SLC1A2) and glutamate transporter 1 (GLT-1) is a protein that in humans is encoded by the SLC1A2 gene.

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Small intestine

The small intestine or small bowel is the part of the gastrointestinal tract between the stomach and the large intestine, and is where most of the end absorption of food takes place.

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Somatostatin

Somatostatin, also known as growth hormone-inhibiting hormone (GHIH) or by several other names, is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones.

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Species

In biology, a species is the basic unit of classification and a taxonomic rank, as well as a unit of biodiversity, but it has proven difficult to find a satisfactory definition.

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Stomach

The stomach (from ancient Greek στόμαχος, stomachos, stoma means mouth) is a muscular, hollow organ in the gastrointestinal tract of humans and many other animals, including several invertebrates.

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Substantia nigra

The substantia nigra (SN) is a basal ganglia structure located in the midbrain that plays an important role in reward and movement.

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Sympathetic nervous system

The sympathetic nervous system (SNS) is one of the two main divisions of the autonomic nervous system, the other being the parasympathetic nervous system.

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Synephrine

Synephrine, or, more specifically, p-synephrine, is an alkaloid, occurring naturally in some plants and animals, and also in approved drugs products as its m-substituted analog known as neo-synephrine.

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T cell

A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.

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TAAR2

Trace amine-associated receptor 2 (TAAR2), formerly known as G protein-coupled receptor 58 (GPR58), is a protein that in humans is encoded by the TAAR2 gene.

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Thermoregulation

Thermoregulation is the ability of an organism to keep its body temperature within certain boundaries, even when the surrounding temperature is very different.

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Thyroid

The thyroid gland, or simply the thyroid, is an endocrine gland in the neck, consisting of two lobes connected by an isthmus.

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Thyronamine

Thyronamine refers both to a molecule, and to derivatives of that molecule: a family of decarboxylated and deiodinated metabolites of the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3).

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Trace amine

Trace amines are an endogenous group of trace amine-associated receptor 1 (TAAR1) agonists – and hence, monoaminergic neuromodulators – that are structurally and metabolically related to classical monoamine neurotransmitters.

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Trace amine-associated receptor

Trace amine-associated receptors (TAARs), sometimes referred to as trace amine receptors (TAs or TARs), are a class of G protein-coupled receptors that were discovered in 2001.

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Transmembrane domain

Transmembrane domain usually denotes a transmembrane segment of single alpha helix of a transmembrane protein.

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Tryptamine

Tryptamine is a monoamine alkaloid.

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Tyramine

Tyramine (also spelled tyramin), also known by several other names is a naturally occurring trace amine derived from the amino acid tyrosine.

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Ventral tegmental area

The ventral tegmental area (VTA) (tegmentum is Latin for covering), also known as the ventral tegmental area of Tsai, or simply ventral tegmentum, is a group of neurons located close to the midline on the floor of the midbrain.

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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2-Methylphenethylamine

2-Methylphenethylamine (2MPEA) is an organic compound with the chemical formula of.

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2C-B-FLY

2C-B-FLY is a psychedelic phenethylamine of the 2C family.

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3-Iodothyronamine

3-Iodothyronamine (T1AM) is an endogenous thyronamine.

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3-Methylphenethylamine

3-Methylphenethylamine (3MPEA) is an organic compound with the chemical formula of.

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4-Methylphenethylamine

4-Methylphenethylamine (4MPEA), also known as para-methylphenethylamine, is an organic compound with the chemical formula of.

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5-APB

5-APB (abbreviation of "5-(2-aminopropyl)benzofuran"; see infobox for the correct IUPAC name) is an empathogenic psychoactive compound of the substituted benzofuran, substituted amphetamine and substituted phenethylamine classes.

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5-APDB

5-(2-Aminopropyl)-2,3-dihydrobenzofuran (5-APDB, 3-Desoxy-MDA, EMA-4) is a putative entactogen drug of the phenethylamine and amphetamine classes.

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5-EAPB

5-EAPB (1-(benzofuran-5-yl)-N-ethylpropan-2-amine) is an entactogenic amphetamine which is structurally related to 5-MAPB and 5-APB.

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5-MAPDB

5-MAPDB (1-(2,3-dihydrobenzofuran-5-yl)-N-methylpropan-2-amine) is a chemical compound which might be an entactogenic drug.

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6-APB

6-APB (6-(2-aminopropyl)benzofuran) is an empathogenic psychoactive compound of the substituted benzofuran, substituted amphetamine and substituted phenethylamine classes.

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6-APDB

6-(2-Aminopropyl)-2,3-dihydrobenzofuran (6-APDB, 4-Desoxy-MDA, EMA-3) is a stimulant and entactogen drug of the phenethylamine and amphetamine classes.

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Redirects here:

HTAAR1, Human trace amine associated receptor 1, Human trace amine-associated receptor 1, TA1 receptor, TAAR1 (gene), TAAR1 agonist, TAAR1 agonists, Trace amine associated receptor 1, Trace amine-associated receptor 1.

References

[1] https://en.wikipedia.org/wiki/TAAR1

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