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TAS-108

Index TAS-108

TAS-108, also known as SR-16234, is a drug discovered by Masato Tanabe and under development by SRI International and Taiho Pharmaceutical. [1]

13 relations: Angiogenesis, Apoptosis, Breast cancer, Cytestrol acetate, Fulvestrant, ICI-164384, Masato Tanabe, Menlo Park, California, National Institutes of Health, SRI International, Steroid hormone, Taiho Pharmaceutical, Tamoxifen.

Angiogenesis

Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Breast cancer

Breast cancer is cancer that develops from breast tissue.

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Cytestrol acetate

Cytestrol acetate is a steroidal antiestrogen and an alkylating antineoplastic agent (i.e., chemotherapeutic) which was developed for the treatment of breast cancer but was never marketed.

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Fulvestrant

Fulvestrant, sold under the brand name Faslodex among others, is a medication used to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women with disease progression as well as HR-positive, HER2-negative advanced breast cancer in combination with palbociclib in women with disease progression after endocrine therapy.

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ICI-164384

ICI-164384, also known as N-n-butyl-N-methyl-11-(3,17β-dihydroxyestra-1,3,5(10)-trien-7α-yl)undecanamide, is a steroidal antiestrogen and a synthetic derivative of estradiol which is closely related to fulvestrant and was never marketed.

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Masato Tanabe

Masato "Mas" Tanabe was a drug researcher at SRI International, where he spent 45 years studying steroid hormones, which are instrumental in combatting breast cancer and prostate cancer.

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Menlo Park, California

Menlo Park is a city at the eastern edge of San Mateo County, in the San Francisco Bay Area of California, in the United States.

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National Institutes of Health

The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.

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SRI International

SRI International (SRI) is an American nonprofit research institute headquartered in Menlo Park, California.

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Steroid hormone

A steroid hormone is a steroid that acts as a hormone.

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Taiho Pharmaceutical

is a Japanese pharmaceutical company, subsidiary of Otsuka Holdings.

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Tamoxifen

Tamoxifen (TMX), sold under the brand name Nolvadex among others, is a medication that is used to prevent breast cancer in women and treat breast cancer in women and men.

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Redirects here:

SR 16234, SR16234, TS 108.

References

[1] https://en.wikipedia.org/wiki/TAS-108

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