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14 relations: Corepressor, Gene, GPS2 (gene), HDAC3, Histone deacetylase, Nuclear receptor co-repressor 1, Nuclear receptor co-repressor 2, Ocular albinism, Protein, Protein–protein interaction, Regulation of gene expression, Sensorineural hearing loss, Signal transduction, WD40 repeat.
Corepressor
In the field of molecular biology, a corepressor is a substance that inhibits the expression of genes.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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GPS2 (gene)
G protein pathway suppressor 2 is a protein that in humans is encoded by the GPS2 gene.
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HDAC3
Histone deacetylase 3 is an enzyme encoded by the HDAC3 gene in both humans and mice.
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Histone deacetylase
Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups (O.
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Nuclear receptor co-repressor 1
The nuclear receptor co-repressor 1 also known as thyroid-hormone- and retinoic-acid-receptor-associated co-repressor 1 (TRAC-1) is a protein that in humans is encoded by the NCOR1 gene.
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Nuclear receptor co-repressor 2
The nuclear receptor co-repressor 2 is a transcriptional coregulatory protein that contains several nuclear receptor-interacting domains.
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Ocular albinism
Ocular albinism is a form of albinism which, in contrast to oculocutaneous albinism, presents primarily in the eyes.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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Regulation of gene expression
Regulation of gene expression includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA), and is informally termed gene regulation.
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Sensorineural hearing loss
Sensorineural hearing loss (SNHL) is a type of hearing loss, or deafness, in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII).
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Signal transduction
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.
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WD40 repeat
The WD40 repeat (also known as the WD or beta-transducin repeat) is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide.
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