80 relations: Acid, Alpharetrovirus, Amino acid, Apoptosis, ATM serine/threonine kinase, Base (chemistry), Base pair, BRCA1, C-terminus, Cancer, Carcinogenesis, Cell cycle, Cell death, Chromosome, Chromosome instability, Conserved sequence, Cre recombinase, Cross-link, DAPI, Dimer (chemistry), DNA, DNA repair, DNA synthesis, Downregulation and upregulation, Extracellular signal–regulated kinases, Fluorescence in situ hybridization, Gastric mucosa, Gene knockout, Homology directed repair, Immunoprecipitation, Ku70, Leukemia, MAPK/ERK pathway, MAPK1, MAPK3, Melanoma, Metaphase, MRE11A, Muller's morphs, Mutation, MYB (gene), N-terminus, Natural killer cell, Neoplasm, Nibrin, Non-homologous end joining, Nuclease, Nucleoprotein, P53, Phenotype, ..., Phenylalanine, Phosphorylation, Protein, Protein complex, Protein dimer, Protein domain, Protein production, Protein quaternary structure, Protein–protein interaction, Rad50, Rap1, Scaffold protein, Sequence motif, Shelterin, Signal transduction, SLX4, Stomach cancer, Telomerase, Telomerase reverse transcriptase, Telomere, TERF1, TERF2IP, TINF2, Titia de Lange, Tumor reversion, Tyrosine, Upstream and downstream (DNA), Viral protein, Werner syndrome helicase, XRCC3. Expand index (30 more) »
Acid
An acid is a molecule or ion capable of donating a hydron (proton or hydrogen ion H+), or, alternatively, capable of forming a covalent bond with an electron pair (a Lewis acid).
New!!: TERF2 and Acid · See more »
Alpharetrovirus
Alpharetrovirus is a genus of the retroviridae family.
New!!: TERF2 and Alpharetrovirus · See more »
Amino acid
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
New!!: TERF2 and Amino acid · See more »
Apoptosis
Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.
New!!: TERF2 and Apoptosis · See more »
ATM serine/threonine kinase
ATM serine/threonine kinase, symbol ATM, is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks.
New!!: TERF2 and ATM serine/threonine kinase · See more »
Base (chemistry)
In chemistry, bases are substances that, in aqueous solution, release hydroxide (OH−) ions, are slippery to the touch, can taste bitter if an alkali, change the color of indicators (e.g., turn red litmus paper blue), react with acids to form salts, promote certain chemical reactions (base catalysis), accept protons from any proton donor, and/or contain completely or partially displaceable OH− ions.
New!!: TERF2 and Base (chemistry) · See more »
Base pair
A base pair (bp) is a unit consisting of two nucleobases bound to each other by hydrogen bonds.
New!!: TERF2 and Base pair · See more »
BRCA1
BRCA1 and BRCA1 are a human gene and its protein product, respectively.
New!!: TERF2 and BRCA1 · See more »
C-terminus
The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).
New!!: TERF2 and C-terminus · See more »
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
New!!: TERF2 and Cancer · See more »
Carcinogenesis
Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells.
New!!: TERF2 and Carcinogenesis · See more »
Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.
New!!: TERF2 and Cell cycle · See more »
Cell death
Cell death is the event of a biological cell ceasing to carry out its functions.
New!!: TERF2 and Cell death · See more »
Chromosome
A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.
New!!: TERF2 and Chromosome · See more »
Chromosome instability
Chromosomal instability (CIN) is a type of genomic instability in which chromosomes are unstable, such that either whole chromosomes or parts of chromosomes are duplicated or deleted.
New!!: TERF2 and Chromosome instability · See more »
Conserved sequence
In evolutionary biology, conserved sequences are similar or identical sequences in nucleic acids (DNA and RNA) or proteins across species (orthologous sequences) or within a genome (paralogous sequences).
New!!: TERF2 and Conserved sequence · See more »
Cre recombinase
Cre recombinase is a tyrosine recombinase enzyme derived from the P1 bacteriophage.
New!!: TERF2 and Cre recombinase · See more »
Cross-link
A cross-link is a bond that links one polymer chain to another.
New!!: TERF2 and Cross-link · See more »
DAPI
DAPI, or 4′,6-diamidino-2-phenylindole, is a fluorescent stain that binds strongly to adenine–thymine rich regions in DNA.
New!!: TERF2 and DAPI · See more »
Dimer (chemistry)
A dimer (di-, "two" + -mer, "parts") is an oligomer consisting of two monomers joined by bonds that can be either strong or weak, covalent or intermolecular.
New!!: TERF2 and Dimer (chemistry) · See more »
DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
New!!: TERF2 and DNA · See more »
DNA repair
DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome.
New!!: TERF2 and DNA repair · See more »
DNA synthesis
DNA synthesis is the natural or artificial creation of deoxyribonucleic acid (DNA) molecules.
New!!: TERF2 and DNA synthesis · See more »
Downregulation and upregulation
In the biological context of organisms' production of gene products, downregulation is the process by which a cell decreases the quantity of a cellular component, such as RNA or protein, in response to an external stimulus.
New!!: TERF2 and Downregulation and upregulation · See more »
Extracellular signal–regulated kinases
In molecular biology, extracellular signal–regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that are involved in functions including the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.
New!!: TERF2 and Extracellular signal–regulated kinases · See more »
Fluorescence in situ hybridization
Fluorescent in situ hybridization (FISH) is a molecular cytogenetic technique that uses fluorescent probes that bind to only those parts of the chromosome with a high degree of sequence complementarity.
New!!: TERF2 and Fluorescence in situ hybridization · See more »
Gastric mucosa
The gastric mucosa is the mucous membrane layer of the stomach which contains the glands and the gastric pits.
New!!: TERF2 and Gastric mucosa · See more »
Gene knockout
A gene knockout (abbreviation: KO) is a genetic technique in which one of an organism's genes is made inoperative ("knocked out" of the organism).
New!!: TERF2 and Gene knockout · See more »
Homology directed repair
Homology directed repair (HDR) is a mechanism in cells to repair double strand DNA lesions.
New!!: TERF2 and Homology directed repair · See more »
Immunoprecipitation
Immunoprecipitation (IP) is the technique of precipitating a protein antigen out of solution using an antibody that specifically binds to that particular protein.
New!!: TERF2 and Immunoprecipitation · See more »
Ku70
Ku70 is a protein that, in humans, is encoded by the XRCC6 gene.
New!!: TERF2 and Ku70 · See more »
Leukemia
Leukemia, also spelled leukaemia, is a group of cancers that usually begin in the bone marrow and result in high numbers of abnormal white blood cells.
New!!: TERF2 and Leukemia · See more »
MAPK/ERK pathway
The MAPK/ERK pathway (also known as the Ras-Raf-MEK-ERK pathway) is a chain of proteins in the cell that communicates a signal from a receptor on the surface of the cell to the DNA in the nucleus of the cell.
New!!: TERF2 and MAPK/ERK pathway · See more »
MAPK1
Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2, is an enzyme that in humans is encoded by the MAPK1 gene.
New!!: TERF2 and MAPK1 · See more »
MAPK3
Mitogen-activated protein kinase 3 is an enzyme that in humans is encoded by the MAPK3 gene.
New!!: TERF2 and MAPK3 · See more »
Melanoma
Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes.
New!!: TERF2 and Melanoma · See more »
Metaphase
Metaphase (from the Greek μετά, "adjacent" and φάσις, "stage") is a stage of mitosis in the eukaryotic cell cycle in which chromosomes are at their second-most condensed and coiled stage (they are at their most condensed in anaphase).
New!!: TERF2 and Metaphase · See more »
MRE11A
Double-strand break repair protein MRE11A is a protein that in humans is encoded by the MRE11A gene.
New!!: TERF2 and MRE11A · See more »
Muller's morphs
Hermann J. Muller (1890–1967), who was a 1946 Nobel Prize winner, coined the terms amorph, hypomorph, hypermorph, antimorph and neomorph to classify mutations based on their behaviour in various genetic situations, as well as gene interaction between themselves.
New!!: TERF2 and Muller's morphs · See more »
Mutation
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.
New!!: TERF2 and Mutation · See more »
MYB (gene)
Myb proto-oncogene protein also known as transcriptional activator Myb is a protein that in humans is encoded by the MYB gene.
New!!: TERF2 and MYB (gene) · See more »
N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
New!!: TERF2 and N-terminus · See more »
Natural killer cell
Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.
New!!: TERF2 and Natural killer cell · See more »
Neoplasm
Neoplasia is a type of abnormal and excessive growth of tissue.
New!!: TERF2 and Neoplasm · See more »
Nibrin
Nibrin, also known as NBN or NBS1, is a protein which in humans is encoded by the NBN gene.
New!!: TERF2 and Nibrin · See more »
Non-homologous end joining
Non-homologous end joining (NHEJ) is a pathway that repairs double-strand breaks in DNA.
New!!: TERF2 and Non-homologous end joining · See more »
Nuclease
A nuclease (also archaically known as nucleodepolymerase or polynucleotidase) is an enzyme capable of cleaving the phosphodiester bonds between monomers of nucleic acids.
New!!: TERF2 and Nuclease · See more »
Nucleoprotein
Nucleoproteins are any proteins that are structurally associated with nucleic acids, either DNA or RNA.
New!!: TERF2 and Nucleoprotein · See more »
P53
Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice).
New!!: TERF2 and P53 · See more »
Phenotype
A phenotype is the composite of an organism's observable characteristics or traits, such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior (such as a bird's nest).
New!!: TERF2 and Phenotype · See more »
Phenylalanine
Phenylalanine (symbol Phe or F) is an α-amino acid with the formula.
New!!: TERF2 and Phenylalanine · See more »
Phosphorylation
In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.
New!!: TERF2 and Phosphorylation · See more »
Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
New!!: TERF2 and Protein · See more »
Protein complex
A protein complex or multiprotein complex is a group of two or more associated polypeptide chains.
New!!: TERF2 and Protein complex · See more »
Protein dimer
In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are usually non-covalently bound.
New!!: TERF2 and Protein dimer · See more »
Protein domain
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.
New!!: TERF2 and Protein domain · See more »
Protein production
Protein production is the biotechnological process of generating a specific protein.
New!!: TERF2 and Protein production · See more »
Protein quaternary structure
Protein quaternary structure is the number and arrangement of multiple folded protein subunits in a multi-subunit complex.
New!!: TERF2 and Protein quaternary structure · See more »
Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
New!!: TERF2 and Protein–protein interaction · See more »
Rad50
DNA repair protein RAD50, also known as RAD50, is a protein that in humans is encoded by the RAD50 gene.
New!!: TERF2 and Rad50 · See more »
Rap1
Rap1 (Ras-proximate-1 or Ras-related protein 1) is a small GTPase, which are small cytosolic proteins that act like cellular switches and are vital for effective signal transduction.
New!!: TERF2 and Rap1 · See more »
Scaffold protein
In biology, scaffold proteins are crucial regulators of many key signalling pathways.
New!!: TERF2 and Scaffold protein · See more »
Sequence motif
In genetics, a sequence motif is a nucleotide or amino-acid sequence pattern that is widespread and has, or is conjectured to have, a biological significance.
New!!: TERF2 and Sequence motif · See more »
Shelterin
Shelterin (also called telosome) is a protein complex known to protect telomeres in many eukaryotes from DNA repair mechanisms, as well as regulate telomerase activity.
New!!: TERF2 and Shelterin · See more »
Signal transduction
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.
New!!: TERF2 and Signal transduction · See more »
SLX4
SLX4 (also known as BTBD12 and FANCP) is a protein involved in DNA repair, where it has important roles in the final steps of homologous recombination.
New!!: TERF2 and SLX4 · See more »
Stomach cancer
Stomach cancer, also known as gastric cancer, is cancer developing from the lining of the stomach.
New!!: TERF2 and Stomach cancer · See more »
Telomerase
Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres.
New!!: TERF2 and Telomerase · See more »
Telomerase reverse transcriptase
Telomerase reverse transcriptase (abbreviated to TERT, or hTERT in humans) is a catalytic subunit of the enzyme telomerase, which, together with the telomerase RNA component (TERC), comprises the most important unit of the telomerase complex.
New!!: TERF2 and Telomerase reverse transcriptase · See more »
Telomere
A telomere is a region of repetitive nucleotide sequences at each end of a chromosome, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes.
New!!: TERF2 and Telomere · See more »
TERF1
Telomeric repeat-binding factor 1 is a protein that in humans is encoded by the TERF1 gene.
New!!: TERF2 and TERF1 · See more »
TERF2IP
Telomeric repeat-binding factor 2-interacting protein 1 is a protein that in humans is encoded by the TERF2IP gene.
New!!: TERF2 and TERF2IP · See more »
TINF2
TERF1-interacting nuclear factor 2 is a protein that in humans is encoded by the TINF2 gene.
New!!: TERF2 and TINF2 · See more »
Titia de Lange
Titia de Lange (born 11 November 1955, in Rotterdam) is an American Cancer Society professor and head of Laboratory Cell Biology and Genetics at Rockefeller University.
New!!: TERF2 and Titia de Lange · See more »
Tumor reversion
Tumor reversion history started in the early 1960s with the flat revertant cells when researchers used the NIH3T3 cells to assay the transforming potential of oncoviruses and oncogenes.
New!!: TERF2 and Tumor reversion · See more »
Tyrosine
Tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins.
New!!: TERF2 and Tyrosine · See more »
Upstream and downstream (DNA)
In molecular biology and genetics, upstream and downstream both refer to relative positions of genetic code in DNA or RNA.
New!!: TERF2 and Upstream and downstream (DNA) · See more »
Viral protein
A viral protein is both a component and a product of a virus.
New!!: TERF2 and Viral protein · See more »
Werner syndrome helicase
"Werner syndrome ATP-dependent helicase" also known as DNA helicase, RecQ-like type 3 is an enzyme that in humans is encoded by the WRN gene.
New!!: TERF2 and Werner syndrome helicase · See more »
XRCC3
DNA repair protein XRCC3 is a protein that in humans is encoded by the XRCC3 gene.
New!!: TERF2 and XRCC3 · See more »
Redirects here:
TERF2 (gene), Telomeric repeat binding protein 2.
References
[1] https://en.wikipedia.org/wiki/TERF2