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31 relations: Bone, Brain, Chronic kidney disease, Cytokine, Diabetes mellitus, Fibrosis, Gene expression, Growth factor, Heart, Kidney, Kidney disease, Ligand, Liver, Paracrine signalling, Peptide, Protein dimer, Protein isoform, Receptor antagonist, Receptor protein serine/threonine kinase, Testicle, TGF beta 1, TGF beta 2, TGF beta receptor 1, TGF beta receptor 2, TGF beta signaling pathway, TGFBR3, TGFβ superfamily receptor, Tissue (biology), Transforming growth factor beta, Transforming growth factor beta superfamily, Transforming growth factor, beta 3.
Bone
A bone is a rigid organ that constitutes part of the vertebrate skeleton.
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Brain
The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.
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Chronic kidney disease
Chronic kidney disease (CKD) is a type of kidney disease in which there is gradual loss of kidney function over a period of months or years.
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Cytokine
Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.
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Diabetes mellitus
Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.
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Fibrosis
Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process.
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Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.
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Growth factor
A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation.
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Heart
The heart is a muscular organ in most animals, which pumps blood through the blood vessels of the circulatory system.
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Kidney
The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.
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Kidney disease
Kidney disease, or renal disease, also known as nephropathy, is damage to or disease of a kidney.
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Ligand
In coordination chemistry, a ligand is an ion or molecule (functional group) that binds to a central metal atom to form a coordination complex.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Paracrine signalling
Paracrine signaling is a form of cell-to-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior of those cells.
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Peptide
Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.
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Protein dimer
In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are usually non-covalently bound.
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Protein isoform
A protein isoform, or "protein variant" is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.
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Receptor antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.
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Receptor protein serine/threonine kinase
In enzymology, a receptor protein serine/threonine kinase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ATP and receptor protein, whereas its two products are ADP and receptor protein phosphate.
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Testicle
The testicle or testis is the male reproductive gland in all animals, including humans.
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TGF beta 1
Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines.
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TGF beta 2
Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development (alternative names: Glioblastoma-derived T-cell suppressor factor, G-TSF, BSC-1 cell growth inhibitor, Polyergin, Cetermin).
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TGF beta receptor 1
Transforming growth factor beta receptor I (activin A receptor type II-like kinase, 53kDa) is a membrane-bound receptor protein for the TGF beta superfamily of signaling ligands.
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TGF beta receptor 2
Transforming growth factor, beta receptor II (70/80kDa) is a TGF beta receptor.
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TGF beta signaling pathway
The transforming growth factor beta (TGFB) signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo including cell growth, cell differentiation, apoptosis, cellular homeostasis and other cellular functions.
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TGFBR3
Betaglycan also known as Transforming growth factor beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan >300 kDa in molecular weight.
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TGFβ superfamily receptor
The Transforming Growth Factor beta (TGFβ) receptors are a superfamily of serine/threonine kinase receptors.
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Tissue (biology)
In biology, tissue is a cellular organizational level between cells and a complete organ.
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Transforming growth factor beta
Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes four different isoforms (TGF-β 1 to 4, HGNC symbols TGFB1, TGFB2, TGFB3, TGFB4) and many other signaling proteins produced by all white blood cell lineages.
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Transforming growth factor beta superfamily
The transforming growth factor beta (TGF-β) superfamily is a large group of structurally related cell regulatory proteins that was named after its first member, TGF-β1, originally described in 1983.
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Transforming growth factor, beta 3
Transforming growth factor beta-3 is a protein that in humans is encoded by the TGFB3 gene.
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References
[1] https://en.wikipedia.org/wiki/TGF_beta_receptor
