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TNF inhibitor

Index TNF inhibitor

A TNF inhibitor is a pharmaceutical drug that suppresses the physiologic response to tumor necrosis factor (TNF), which is part of the inflammatory response. [1]

65 relations: Adalimumab, Ankylosing spondylitis, Asthma, Azathioprine, Breast cancer, Bupropion, Cannabis (drug), CCL2, Certolizumab pegol, Ciclosporin, Collagenase, Crohn's disease, Curcumin, Disease-modifying antirheumatic drug, Echinacea purpurea, Etanercept, Food and Drug Administration, Fusion protein, Gemcitabine, George Kollias (biologist), Golimumab, Green tea, Hallucinogen, Hepatosplenic T-cell lymphoma, Hidradenitis suppurativa, Inflammation, Inflammatory bowel disease, Infliximab, Interleukin 6, Lasker Award, Legionella, Lenalidomide, Listeria, Lysergic acid 2,4-dimethylazetidide, Lysergic acid diethylamide, Marc Feldmann, Medication, Mercaptopurine, Metalloproteinase, Methotrexate, Molar concentration, Monoclonal antibody, Mycobacterium tuberculosis, Ovarian cancer, Pancreatic cancer, Pentoxifylline, Phenolic content in tea, Polyclonal antibodies, Pomalidomide, Psoriasis, ..., Ravinder N. Maini, Renal cell carcinoma, Rheumatoid arthritis, Synovial fluid, Synovial membrane, TCB-2, Thalidomide, Tuberculosis, Tumor necrosis factor superfamily, Turmeric, Ulcerative colitis, Ustekinumab, Xanthine, 2,5-Dimethoxy-4-iodoamphetamine, 5-HT2A receptor. Expand index (15 more) »


Adalimumab, sold under the trade name Humira among others, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, chronic psoriasis, hidradenitis suppurativa, and juvenile idiopathic arthritis.

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Ankylosing spondylitis

Ankylosing spondylitis (AS) is a type of arthritis in which there is long term inflammation of the joints of the spine.

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Asthma is a common long-term inflammatory disease of the airways of the lungs.

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Azathioprine (AZA), sold under the brand name Imuran among others, is an immunosuppressive medication.

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Breast cancer

Breast cancer is cancer that develops from breast tissue.

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Bupropion, sold under the brand names Wellbutrin and Zyban among others, is a medication primarily used as an antidepressant and smoking cessation aid.

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Cannabis (drug)

Cannabis, also known as marijuana among other names, is a psychoactive drug from the ''Cannabis'' plant intended for medical or recreational use.

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For the ICAO airport code see Candle Lake Airpark, for the diradical compound see Dichlorocarbene. The chemokine (C-C motif) ligand 2 (CCL2) is also referred to as monocyte chemoattractant protein 1 (MCP1) and small inducible cytokine A2.

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Certolizumab pegol

Certolizumab pegol (CDP870, tradename Cimzia) is a biologic medication for the treatment of Crohn's disease, rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis.

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Ciclosporin, also spelled cyclosporine and cyclosporin, is an immunosuppressant medication and natural product.

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Collagenases are enzymes that break the peptide bonds in collagen.

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Crohn's disease

Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any part of the gastrointestinal tract from mouth to anus.

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Curcumin is a bright yellow chemical produced by some plants.

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Disease-modifying antirheumatic drug

Disease-modifying antirheumatic drugs (DMARDs) is a category of otherwise unrelated drugs defined by their use in rheumatoid arthritis to slow down disease progression.

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Echinacea purpurea

Echinacea purpurea (eastern purple coneflower, hedgehog coneflower, or purple coneflower) is a North American species of flowering plant in the sunflower family.

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Etanercept (trade name Enbrel) is a biopharmaceutical that treats autoimmune diseases by interfering with tumor necrosis factor (TNF, a soluble inflammatory cytokine) by acting as a TNF inhibitor.

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Food and Drug Administration

The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.

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Fusion protein

Fusion proteins or chimeric (\kī-ˈmir-ik) proteins (literally, made of parts from different sources) are proteins created through the joining of two or more genes that originally coded for separate proteins.

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Gemcitabine, sold under the brand name Gemzar, among others, is a chemotherapy medication used to treat a number of types of cancer.

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George Kollias (biologist)

George Kollias (Greek: Γιώργος Κόλλιας; born November 9, 1958 in Athens) is a Greek biologist, Member of the and Professor of Physiology at the of the University of Athens.

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Golimumab (CNTO 148) is a human monoclonal antibody which is used as an immunosuppressive drug and marketed under the brand name Simponi.

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Green tea

Green tea is a type of tea that is made from Camellia sinensis leaves that have not undergone the same withering and oxidation process used to make oolong teas and black teas.

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A hallucinogen is a psychoactive agent which can cause hallucinations, perceptual anomalies, and other substantial subjective changes in thoughts, emotion, and consciousness.

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Hepatosplenic T-cell lymphoma

Hepatosplenic T-cell lymphoma is a rare and generally incurable form of lymphoma.

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Hidradenitis suppurativa

Hidradenitis suppurativa (HS), also known as acne inversa, is a long term skin disease characterized by the occurrence of inflamed and swollen lumps.

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Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Inflammatory bowel disease

Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.

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Infliximab (trade names Remicade among others) is a chimeric monoclonal antibody biologic drug that works against tumor necrosis factor alpha (TNF-α) and is used to treat autoimmune diseases.

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Interleukin 6

Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine.

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Lasker Award

The Lasker Awards have been awarded annually since 1945 to living persons who have made major contributions to medical science or who have performed public service on behalf of medicine.

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The genus Legionella is a pathogenic group of Gram-negative bacteria that includes the species L. pneumophila, causing legionellosis (all illnesses caused by Legionella) including a pneumonia-type illness called Legionnaires' disease and a mild flu-like illness called Pontiac fever.

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Lenalidomide (trade name Revlimid) is a derivative of thalidomide introduced in 2004.

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Listeria is a genus of bacteria that, until 1992, contained 10 known species, each containing two subspecies.

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Lysergic acid 2,4-dimethylazetidide

Lysergic acid 2,4-dimethylazetidide (LA-SS-Az, LSZ) is an analog of LSD developed by the team led by David E. Nichols at Purdue University.

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Lysergic acid diethylamide

Lysergic acid diethylamide (LSD), also known as acid, is a psychedelic drug known for its psychological effects, which may include altered awareness of one's surroundings, perceptions, and feelings as well as sensations and images that seem real though they are not.

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Marc Feldmann

Sir Marc Feldmann, (born 2 December 1944), is an Australian immunologist, and a professor at the University of Oxford.

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A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

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Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases.

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A metalloproteinase, or metalloprotease, is any protease enzyme whose catalytic mechanism involves a metal.

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Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune system suppressant.

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Molar concentration

Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular of a solute in a solution, in terms of amount of substance per unit volume of solution.

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Monoclonal antibody

Monoclonal antibodies (mAb or moAb) are antibodies that are made by identical immune cells that are all clones of a unique parent cell.

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Mycobacterium tuberculosis

Mycobacterium tuberculosis is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis.

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Ovarian cancer

Ovarian cancer is a cancer that forms in or on an ovary.

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Pancreatic cancer

Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass.

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Pentoxifylline, also known as oxpentifylline, is a xanthine derivative used as a drug to treat muscle pain in people with peripheral artery disease. It is generic and sold under many brand names worldwide.Drugs.com. Page accessed Feb 1, 206.

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Phenolic content in tea

The phenolic content in tea refers to the phenols and polyphenols, natural plant compounds which are found in tea.

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Polyclonal antibodies

Polyclonal antibodies (pAbs) are antibodies that are secreted by different B cell lineages within the body (whereas monoclonal antibodies come from a single cell lineage).

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Pomalidomide (INN; marketed as Pomalyst in the U.S. and Imnovid in the EU and Russia) is a derivative of thalidomide marketed by Celgene.

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Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin.

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Ravinder N. Maini

Sir Ravinder Nath Maini FMedSci (born 17 November 1937) is rheumatology professor at the Kennedy Institute, part of Imperial College London.

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Renal cell carcinoma

Renal cell carcinoma (RCC) is a kidney cancer that originates in the lining of the proximal convoluted tubule, a part of the very small tubes in the kidney that transport primary urine.

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Rheumatoid arthritis

Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.

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Synovial fluid

Synovial fluid, also called synovia,help 1 is a viscous, non-Newtonian fluid found in the cavities of synovial joints.

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Synovial membrane

The synovial membrane (also known as synovium or stratum synoviale) is a specialized connective tissue that lines the inner surface of capsules of synovial joints and tendon sheath.

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TCB-2 is a hallucinogen discovered in 2006 by Thomas McLean working in the lab of David Nichols at Purdue University where it was named 2C-BCB.

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Thalidomide, sold under the brand name Immunoprin, among others, is an immunomodulatory drug and the prototype of the thalidomide class of drugs.

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Tuberculosis (TB) is an infectious disease usually caused by the bacterium Mycobacterium tuberculosis (MTB).

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Tumor necrosis factor superfamily

The tumor necrosis factor (TNF) superfamily is a protein superfamily of type II transmembrane proteins containing TNF homology domain and forming trimers.

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Turmeric (Curcuma longa) is a rhizomatous herbaceous perennial flowering plant of the ginger family, Zingiberaceae.

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Ulcerative colitis

Ulcerative colitis (UC) is a long-term condition that results in inflammation and ulcers of the colon and rectum.

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Ustekinumab, sold under the brand name Stelara, is a human monoclonal antibody used to treat psoriasis.

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Xanthine (or; archaically xanthic acid) (3,7-dihydropurine-2,6-dione), is a purine base found in most human body tissues and fluids and in other organisms.

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2,5-Dimethoxy-4-iodoamphetamine (DOI) is a psychedelic drug and a substituted amphetamine.

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5-HT2A receptor

The mammalian 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR).

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Anti-TNF, Anti-TNF-alpha, TNF Inhibitors, TNF alpha blocker, TNF alpha inhibitor, TNF antagonist, TNF blockers, TNF ihhibition, TNF inhibition, TNF inhibitors, TNF-alpha inhibitor, TNF-α inhibitor, TNFi, Tnf alpha blockers.


[1] https://en.wikipedia.org/wiki/TNF_inhibitor

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