Faster access than browser!
186 relations: Activated PI3K delta syndrome, Adenosine deaminase, Albinism, Amyloid, Angioedema, Antibiotic, Antibody, Antiviral drug, Artemis (protein), Ataxia-telangiectasia, Autoimmune disease, Autoimmune lymphoproliferative syndrome, Autoimmune polyendocrine syndrome, B cell, B-cell activating factor, B-cell linker, BCL10, Beta-actin, Blau syndrome, Bloom syndrome, Bruton's tyrosine kinase, C8 complex, Cancer, CARD11, Cartilage–hair hypoplasia, Caspase 10, Caspase 8, CD154, CD19, CD25 deficiency, CD278, CD3 (immunology), CD4, CD40 (protein), CD79, CD8, CD80, Cell-mediated immunity, Cernunnos deficiency, Chédiak–Higashi syndrome, Chemotaxis, Child, Chronic granulomatous disease, Chronic mucocutaneous candidiasis, Cold urticaria, Common variable immunodeficiency, Complement component 1q, Complement component 1r, Complement component 2, Complement component 3, ..., Complement component 4, Complement component 5, Complement component 6, Complement component 7, Complement component 9, Complement deficiency, Complement factor I, Complement system, Complete blood count, Cyclic neutropenia, Cytochrome b-245, alpha polypeptide, Cytokine, Deficiency of the interleukin-1–receptor antagonist, Developmental disability, DiGeorge syndrome, DNA ligase, DNA repair, DOCK8 deficiency, Dyskeratosis congenita, Epidermodysplasia verruciformis, Factor D, Factor H, Familial Mediterranean fever, Fas ligand, Fas receptor, Gamma delta T cell, Genetic disorder, GFI1, Glycogen storage disease type I, Graft-versus-host disease, Granulocyte, Griscelli syndrome, Heart, Hematopoietic stem cell transplantation, Hemolytic-uremic syndrome, Hemophagocytic lymphohistiocytosis, Hepatic veno-occlusive disease, Hermansky–Pudlak syndrome, Herpesviral encephalitis, HLA-DR, Hoyeraal-Hreidarsson syndrome, Humoral immune deficiency, Hyper IgM syndrome, Hyper-IgD syndrome, Hyperimmunoglobulin E syndrome, Hypohidrotic ectodermal dysplasia, IκBα, IKBKG, IL2RA, Immune system, Immunodeficiency, Immunoglobulin A, Immunoglobulin G, Immunoglobulin heavy chain, Immunoglobulin light chain, Immunoglobulin M, Immunoglobulin therapy, Immunosuppression, Infection, Innate immune system, Interferon-gamma receptor, Interleukin 12, Interleukin 23 subunit alpha, Interleukin 7, Interleukin-12 subunit beta, International Union of Immunological Societies, IPEX syndrome, IRAK4, Kostmann syndrome, Leukocyte adhesion deficiency, Lymphocyte, Lymphoma, Macrophage, Majeed syndrome, MALT1, Mannan-binding lectin, MASP2 (protein), Membranoproliferative glomerulonephritis, MHC class I, MHC class II, Mitogen, Monocyte, MRE11A, Muckle–Wells syndrome, MYD88, Myelodysplastic syndrome, NALP3, Natural killer cell, Neonatal-onset multisystem inflammatory disease, Neutrophil cytosolic factor 1, Neutrophil cytosolic factor 2, Neutrophil elastase, Neutrophil immunodeficiency syndrome, Neutrophil-specific granule deficiency, Nijmegen breakage syndrome, Nitro blue tetrazolium chloride, Normality (behavior), Ogden Bruton, Omenn syndrome, Osteochondrodysplasia, PAPA syndrome, Papillon–Lefèvre syndrome, Paroxysmal nocturnal hemoglobinuria, Perforin, Periodic fever syndrome, Phagocyte, Phagocytosis, Plasma cell, Properdin, PTPRC, Pulmonary alveolar proteinosis, Purine nucleoside phosphorylase deficiency, Pus, RAC2, Recombination-activating gene, Reticular dysgenesis, Selective immunoglobulin A deficiency, Severe combined immunodeficiency, Shwachman–Diamond syndrome, Skin, STAT1, STAT5B, Syntaxin, T cell, Thymoma with immunodeficiency, Thymus, TNF receptor associated periodic syndrome, TNF receptor superfamily, Transient hypogammaglobulinemia of infancy, Trypanosomiasis, UNC13D, WHIM syndrome, Wiskott–Aldrich syndrome, X-linked agammaglobulinemia, X-linked lymphoproliferative disease, ZAP70. Expand index (136 more) »
Activated PI3K delta syndrome
Activated PI3K delta syndrome is a primary immunodeficiency disease caused by activating gain of function mutations in the PIK3CD gene.
New!!: Primary immunodeficiency and Activated PI3K delta syndrome · See more »
Adenosine deaminase
Adenosine deaminase (also known as adenosine aminohydrolase, or ADA) is an enzyme involved in purine metabolism.
New!!: Primary immunodeficiency and Adenosine deaminase · See more »
Albinism
Albinism in humans is a congenital disorder characterized by the complete or partial absence of pigment in the skin, hair and eyes.
New!!: Primary immunodeficiency and Albinism · See more »
Amyloid
Amyloids are aggregates of proteins that become folded into a shape that allows many copies of that protein to stick together forming fibrils.
New!!: Primary immunodeficiency and Amyloid · See more »
Angioedema
Angioedema is an area of swelling of the lower layer of skin and tissue just under the skin or mucous membranes.
New!!: Primary immunodeficiency and Angioedema · See more »
Antibiotic
An antibiotic (from ancient Greek αντιβιοτικά, antibiotiká), also called an antibacterial, is a type of antimicrobial drug used in the treatment and prevention of bacterial infections.
New!!: Primary immunodeficiency and Antibiotic · See more »
Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.
New!!: Primary immunodeficiency and Antibody · See more »
Antiviral drug
Antiviral drugs are a class of medication used specifically for treating viral infections rather than bacterial ones.
New!!: Primary immunodeficiency and Antiviral drug · See more »
Artemis (protein)
Artemis is a protein that in humans is encoded by the DCLRE1C (DNA cross-link repair 1C) gene.
New!!: Primary immunodeficiency and Artemis (protein) · See more »
Ataxia-telangiectasia
Ataxia-telangiectasia (AT or A-T), also referred to as ataxia-telangiectasia syndrome or Louis–Bar syndrome, is a rare, neurodegenerative, autosomal recessive disease causing severe disability.
New!!: Primary immunodeficiency and Ataxia-telangiectasia · See more »
Autoimmune disease
An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.
New!!: Primary immunodeficiency and Autoimmune disease · See more »
Autoimmune lymphoproliferative syndrome
Autoimmune lymphoproliferative syndrome (ALPS), also known as Canale-Smith syndrome,Straus SE, Jaffe ES, Puck JM et al.
New!!: Primary immunodeficiency and Autoimmune lymphoproliferative syndrome · See more »
Autoimmune polyendocrine syndrome
Autoimmune polyendocrine syndromes (APSs), also called autoimmune polyglandular syndromes (APSs), polyglandular autoimmune syndromes (PGASs), or polyendocrine autoimmune syndromes, are a heterogeneous group of rare diseases characterized by autoimmune activity against more than one endocrine organ, although non-endocrine organs can be affected.There are three types of APS or (in terms that mean the same thing) three APSs, and there are a number of other diseases which have endocrine autoimmunity.
New!!: Primary immunodeficiency and Autoimmune polyendocrine syndrome · See more »
B cell
B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype.
New!!: Primary immunodeficiency and B cell · See more »
B-cell activating factor
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.
New!!: Primary immunodeficiency and B-cell activating factor · See more »
B-cell linker
The B-cell linker protein is encoded by the BLNK gene and is an adaptor protein also known as SLP-65, BASH, and BCA.
New!!: Primary immunodeficiency and B-cell linker · See more »
BCL10
B-cell lymphoma/leukemia 10 is a protein that in humans is encoded by the BCL10 gene.
New!!: Primary immunodeficiency and BCL10 · See more »
Beta-actin
Beta-actin (human gene and protein symbol ACTB/ACTB) is one of six different actin isoforms which have been identified in humans.
New!!: Primary immunodeficiency and Beta-actin · See more »
Blau syndrome
Blau Syndrome is an autosomal dominant genetic inflammatory disorder which affects the skin, eyes, and joints.
New!!: Primary immunodeficiency and Blau syndrome · See more »
Bloom syndrome
Bloom syndrome (often abbreviated as BS in literature), also known as Bloom-Torre-Machacek syndrome, is a rare autosomal recessive disorder characterized by short stature, predisposition to the development of cancer and genomic instability.
New!!: Primary immunodeficiency and Bloom syndrome · See more »
Bruton's tyrosine kinase
Bruton's tyrosine kinase (abbreviated Btk or BTK) also known as tyrosine-protein kinase BTK is an enzyme that in humans is encoded by the BTK gene.
New!!: Primary immunodeficiency and Bruton's tyrosine kinase · See more »
C8 complex
Complement component 8 is a protein involved in the complement system.
New!!: Primary immunodeficiency and C8 complex · See more »
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
New!!: Primary immunodeficiency and Cancer · See more »
CARD11
Caspase recruitment domain-containing protein 11 also known as CARD-containing MAGUK protein 1 (Carma 1) is a protein that in humans is encoded by the CARD11 gene.
New!!: Primary immunodeficiency and CARD11 · See more »
Cartilage–hair hypoplasia
Cartilage–hair hypoplasia (CHH), also known as McKusick type metaphyseal chondrodysplasia,James, William; Berger, Timothy; Elston, Dirk (2005).
New!!: Primary immunodeficiency and Cartilage–hair hypoplasia · See more »
Caspase 10
Caspase-10 is an enzyme that, in humans, is encoded by the CASP10 gene.
New!!: Primary immunodeficiency and Caspase 10 · See more »
Caspase 8
Caspase-8 is a caspase protein, encoded by the CASP8 gene.
New!!: Primary immunodeficiency and Caspase 8 · See more »
CD154
CD154, also called CD40 ligand or CD40L, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules.
New!!: Primary immunodeficiency and CD154 · See more »
CD19
B-lymphocyte antigen CD19, also known as CD19 molecule ('''C'''luster of '''D'''ifferentiation 19), B-Lymphocyte Surface Antigen B4, T-Cell Surface Antigen Leu-12 and CVID3 is a transmembrane protein that in humans is encoded by the gene CD19.
New!!: Primary immunodeficiency and CD19 · See more »
CD25 deficiency
CD25 deficiency or interleukin 2 receptor alpha deficiency is an immunodeficiency disorder associated with mutations in the interleukin 2 receptor alpha (CD25) (IL2RA) gene.
New!!: Primary immunodeficiency and CD25 deficiency · See more »
CD278
Inducible T-cell costimulator is an immune checkpoint protein that in humans is encoded by the ICOS gene.
New!!: Primary immunodeficiency and CD278 · See more »
CD3 (immunology)
In immunology, the CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8+ naive T cells) and also T helper cells (CD4+ naive T cells).
New!!: Primary immunodeficiency and CD3 (immunology) · See more »
CD4
In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells.
New!!: Primary immunodeficiency and CD4 · See more »
CD40 (protein)
Cluster of differentiation 40, CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation.
New!!: Primary immunodeficiency and CD40 (protein) · See more »
CD79
CD79 ('''C'''luster of '''D'''ifferentiation 79) is a transmembrane protein that forms a complex with the B-cell receptor (BCR) and generates a signal following recognition of antigen by the BCR.
New!!: Primary immunodeficiency and CD79 · See more »
CD8
CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR).
New!!: Primary immunodeficiency and CD8 · See more »
CD80
Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival.
New!!: Primary immunodeficiency and CD80 · See more »
Cell-mediated immunity
Cell-mediated immunity is an immune response that does not involve antibodies, but rather involves the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen.
New!!: Primary immunodeficiency and Cell-mediated immunity · See more »
Cernunnos deficiency
Cernunnos deficiency is a form of combined immunodeficiency characterized by microcephaly, due to mutations in the NHEJ1 gene, it is inherited via autosomal recessive manner Management for this condition is antiviral prophylaxis and antibiotic treatment.
New!!: Primary immunodeficiency and Cernunnos deficiency · See more »
Chédiak–Higashi syndrome
Chédiak–Higashi syndrome is a rare autosomal recessive disorder that arises from a mutation of a lysosomal trafficking regulator protein, which leads to a decrease in phagocytosis.
New!!: Primary immunodeficiency and Chédiak–Higashi syndrome · See more »
Chemotaxis
Chemotaxis (from chemo- + taxis) is the movement of an organism in response to a chemical stimulus.
New!!: Primary immunodeficiency and Chemotaxis · See more »
Child
Biologically, a child (plural: children) is a human being between the stages of birth and puberty.
New!!: Primary immunodeficiency and Child · See more »
Chronic granulomatous disease
Chronic granulomatous disease (CGD) (also known as Bridges–Good syndrome, chronic granulomatous disorder, and Quie syndrome) is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly the superoxide radical due to defective phagocyte NADPH oxidase) used to kill certain ingested pathogens.
New!!: Primary immunodeficiency and Chronic granulomatous disease · See more »
Chronic mucocutaneous candidiasis
Chronic mucocutaneous candidiasis is an immune disorder of T cells, it is characterized by chronic infections with Candida that are limited to mucosal surfaces, skin, and nails.
New!!: Primary immunodeficiency and Chronic mucocutaneous candidiasis · See more »
Cold urticaria
Cold urticaria (essentially meaning "cold hives") is a disorder where hives (urticaria) or large red welts form on the skin after exposure to a cold stimulus.
New!!: Primary immunodeficiency and Cold urticaria · See more »
Common variable immunodeficiency
Common variable immunodeficiency (CVID) is an immune disorder characterized by recurrent infections and low antibody levels, specifically in immunoglobulin (Ig) types IgG, IgM and IgA.
New!!: Primary immunodeficiency and Common variable immunodeficiency · See more »
Complement component 1q
The complement component 1q (or simply C1q) is a protein complex involved in the complement system, which is part of the innate immune system.
New!!: Primary immunodeficiency and Complement component 1q · See more »
Complement component 1r
Complement C1r subcomponent (activated complement C1r, C overbar 1r esterase, C1r) is a protein involved in the complement system of the innate immune system.
New!!: Primary immunodeficiency and Complement component 1r · See more »
Complement component 2
Complement C2 is a protein that in humans is encoded by the C2 gene.
New!!: Primary immunodeficiency and Complement component 2 · See more »
Complement component 3
Complement component 3, often simply called C3, is a protein of the immune system.
New!!: Primary immunodeficiency and Complement component 3 · See more »
Complement component 4
Complement component 4 (C4), in humans, is a protein involved in the intricate complement system, originating from the human leukocyte antigen (HLA) system.
New!!: Primary immunodeficiency and Complement component 4 · See more »
Complement component 5
Complement component 5 is a protein that in humans is encoded by the C5 gene.
New!!: Primary immunodeficiency and Complement component 5 · See more »
Complement component 6
Complement component 6 is a protein that in humans is encoded by the C6 gene.
New!!: Primary immunodeficiency and Complement component 6 · See more »
Complement component 7
Complement component 7 is a protein involved in the complement system of the innate immune system.
New!!: Primary immunodeficiency and Complement component 7 · See more »
Complement component 9
Complement component 9 (C9) is a protein involved in the complement system, which is part of the innate immune system.
New!!: Primary immunodeficiency and Complement component 9 · See more »
Complement deficiency
Complement deficiency is an immunodeficiency of absent or suboptimal functioning of one of the complement system proteins.
New!!: Primary immunodeficiency and Complement deficiency · See more »
Complement factor I
Complement factor I, also known as C3b/C4b inactivator, is a protein that in humans is encoded by the CFI gene.
New!!: Primary immunodeficiency and Complement factor I · See more »
Complement system
The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's cell membrane.
New!!: Primary immunodeficiency and Complement system · See more »
Complete blood count
A complete blood count (CBC), also known as a complete blood cell count, full blood count (FBC), or full blood exam (FBE), is a blood panel requested by a doctor or other medical professional that gives information about the cells in a patient's blood, such as the cell count for each cell type and the concentrations of various proteins and minerals.
New!!: Primary immunodeficiency and Complete blood count · See more »
Cyclic neutropenia
Cyclic neutropenia (or cyclical neutropenia) is a form of neutropenia that tends to occur every three weeks and lasting three to six days at a time due to changing rates of cell production by the bone marrow.
New!!: Primary immunodeficiency and Cyclic neutropenia · See more »
Cytochrome b-245, alpha polypeptide
Cytochrome b-245 light chain is a protein that in humans is encoded by the CYBA gene involved in superoxide production and phagocytosis.
New!!: Primary immunodeficiency and Cytochrome b-245, alpha polypeptide · See more »
Cytokine
Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.
New!!: Primary immunodeficiency and Cytokine · See more »
Deficiency of the interleukin-1–receptor antagonist
Deficiency of the interleukin-1–receptor antagonist (DIRA) is a autosomal recessive, genetic autoinflammatory syndrome resulting from mutations in IL1RN, the gene encoding the interleukin 1 receptor antagonist.
New!!: Primary immunodeficiency and Deficiency of the interleukin-1–receptor antagonist · See more »
Developmental disability
Developmental disability is a diverse group of chronic conditions that are due to mental or physical impairments that arise before adulthood.
New!!: Primary immunodeficiency and Developmental disability · See more »
DiGeorge syndrome
DiGeorge syndrome, also known as 22q11.2 deletion syndrome, is a syndrome caused by the deletion of a small segment of chromosome 22.
New!!: Primary immunodeficiency and DiGeorge syndrome · See more »
DNA ligase
DNA ligase is a specific type of enzyme, a ligase, that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond.
New!!: Primary immunodeficiency and DNA ligase · See more »
DNA repair
DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome.
New!!: Primary immunodeficiency and DNA repair · See more »
DOCK8 deficiency
DOCK8 deficiency, also called DOCK8 immunodeficiency syndrome, is the autosomal recessive form of hyperimmunoglobulin E syndrome, a genetic disorder characterized by elevated immunoglobulin E levels, eosinophilia, and recurrent infections with staphylococcus and viruses.
New!!: Primary immunodeficiency and DOCK8 deficiency · See more »
Dyskeratosis congenita
Dyskeratosis congenita (DKC), also called Zinsser-Cole-Engman syndrome,James, William; Berger, Timothy; Elston, Dirk (2005).
New!!: Primary immunodeficiency and Dyskeratosis congenita · See more »
Epidermodysplasia verruciformis
Epidermodysplasia verruciformis (EV), also known as treeman syndrome, is an extremely rare autosomal recessive hereditary skin disorder associated with a high risk of skin cancer.
New!!: Primary immunodeficiency and Epidermodysplasia verruciformis · See more »
Factor D
Factor D (C3 proactivator convertase, properdin factor D esterase, factor D (complement), complement factor D, CFD, adipsin) a protein which in humans is encoded by the CFD gene.
New!!: Primary immunodeficiency and Factor D · See more »
Factor H
Factor H is a member of the regulators of complement activation family and is a complement control protein.
New!!: Primary immunodeficiency and Factor H · See more »
Familial Mediterranean fever
Familial Mediterranean fever (FMF) is a hereditary inflammatory disorder.
New!!: Primary immunodeficiency and Familial Mediterranean fever · See more »
Fas ligand
Fas ligand (FasL or CD95L) is a type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family.
New!!: Primary immunodeficiency and Fas ligand · See more »
Fas receptor
The first apoptosis signal receptor (Fas or FasR), also known as apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6) is a protein that in humans is encoded by the FAS gene.
New!!: Primary immunodeficiency and Fas receptor · See more »
Gamma delta T cell
Gamma delta T cells (γδ T cells) are T cells that have a distinctive T-cell receptor (TCR) on their surface.
New!!: Primary immunodeficiency and Gamma delta T cell · See more »
Genetic disorder
A genetic disorder is a genetic problem caused by one or more abnormalities in the genome.
New!!: Primary immunodeficiency and Genetic disorder · See more »
GFI1
Zinc finger protein Gfi-1 is a protein that in humans is encoded by the GFI1 gene.
New!!: Primary immunodeficiency and GFI1 · See more »
Glycogen storage disease type I
Glycogen storage disease type I (GSD I) or von Gierke disease, is the most common of the glycogen storage diseases.
New!!: Primary immunodeficiency and Glycogen storage disease type I · See more »
Graft-versus-host disease
Graft-versus-host disease (GvHD) is a medical complication following the receipt of transplanted tissue from a genetically different person.
New!!: Primary immunodeficiency and Graft-versus-host disease · See more »
Granulocyte
Granulocytes are a category of white blood cells characterized by the presence of granules in their cytoplasm.
New!!: Primary immunodeficiency and Granulocyte · See more »
Griscelli syndrome
Griscelli syndrome is a rare autosomal recessive disorder characterized by albinism (hypopigmentation) with immunodeficiency, that usually causes death by early childhood.
New!!: Primary immunodeficiency and Griscelli syndrome · See more »
Heart
The heart is a muscular organ in most animals, which pumps blood through the blood vessels of the circulatory system.
New!!: Primary immunodeficiency and Heart · See more »
Hematopoietic stem cell transplantation
Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood.
New!!: Primary immunodeficiency and Hematopoietic stem cell transplantation · See more »
Hemolytic-uremic syndrome
Hemolytic-uremic syndrome (HUS) is a disease characterized by a triad of hemolytic anemia (anemia caused by destruction of red blood cells), acute kidney failure (uremia), and a low platelet count (thrombocytopenia).
New!!: Primary immunodeficiency and Hemolytic-uremic syndrome · See more »
Hemophagocytic lymphohistiocytosis
Hemophagocytic lymphohistiocytosis (HLH), also known as haemophagocytic lymphohistiocytosis (British spelling), and hemophagocytic or haemophagocytic syndrome, is an uncommon hematologic disorder seen more often in children than in adults.
New!!: Primary immunodeficiency and Hemophagocytic lymphohistiocytosis · See more »
Hepatic veno-occlusive disease
Hepatic veno-occlusive disease or veno-occlusive disease with immunodeficiency (VODI) is a condition in which some of the small veins in the liver are obstructed.
New!!: Primary immunodeficiency and Hepatic veno-occlusive disease · See more »
Hermansky–Pudlak syndrome
Heřmanský–Pudlák syndrome (often written Hermansky–Pudlak syndrome or abbreviated HPS) is an extremely rare autosomal recessive disorder which results in oculocutaneous albinism (decreased pigmentation), bleeding problems due to a platelet abnormality (platelet storage pool defect), and storage of an abnormal fat-protein compound (lysosomal accumulation of ceroid lipofuscin).
New!!: Primary immunodeficiency and Hermansky–Pudlak syndrome · See more »
Herpesviral encephalitis
Herpesviral encephalitis is encephalitis due to herpes simplex virus.
New!!: Primary immunodeficiency and Herpesviral encephalitis · See more »
HLA-DR
HLA-DR is an MHC class II cell surface receptor encoded by the human leukocyte antigen complex on chromosome 6 region 6p21.31.
New!!: Primary immunodeficiency and HLA-DR · See more »
Hoyeraal-Hreidarsson syndrome
Hoyeraal-Hreidarsson syndrome (HHS) is a very rare multisystem X-linked recessive disorder characterized by excessively short telomeres and is considered a severe form of dyskeratosis congenita.
New!!: Primary immunodeficiency and Hoyeraal-Hreidarsson syndrome · See more »
Humoral immune deficiency
Humoral immune deficiencies are conditions which cause impairment of humoral immunity, which can lead to immunodeficiency.
New!!: Primary immunodeficiency and Humoral immune deficiency · See more »
Hyper IgM syndrome
Hyper IgM syndromes is a group of primary immune deficiency disorders characterized by defective CD40 signaling; via B cells affecting class switch recombination (CSR) and somatic hypermutation.
New!!: Primary immunodeficiency and Hyper IgM syndrome · See more »
Hyper-IgD syndrome
Hyperimmunoglobulinemia D with recurrent fever (HIDS) is a periodic fever syndrome originally described in 1984 by the internist Jos van der Meer, then at Leiden University Medical Centre.
New!!: Primary immunodeficiency and Hyper-IgD syndrome · See more »
Hyperimmunoglobulin E syndrome
Hyperimmunoglobulinemia E syndrome (HIES), of which the autosomal dominant form is called Job's syndrome or Buckley syndrome, is a heterogeneous group of immune disorders.
New!!: Primary immunodeficiency and Hyperimmunoglobulin E syndrome · See more »
Hypohidrotic ectodermal dysplasia
Hypohidrotic ectodermal dysplasia (also known as "anhidrotic ectodermal dysplasia", and "Christ-Siemens-Touraine syndrome"James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders..) is one of about 150 types of ectodermal dysplasia in humans.
New!!: Primary immunodeficiency and Hypohidrotic ectodermal dysplasia · See more »
IκBα
IκBα (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha) is one member of a family of cellular proteins that function to inhibit the NF-κB transcription factor.
New!!: Primary immunodeficiency and IκBα · See more »
IKBKG
NF-kappa-B essential modulator (NEMO) also known as inhibitor of nuclear factor kappa-B kinase subunit gamma (IKK-γ) is a protein that in humans is encoded by the IKBKG gene.
New!!: Primary immunodeficiency and IKBKG · See more »
IL2RA
Interleukin-2 receptor alpha chain (also called CD25) is a protein that in humans is encoded by the IL2RA gene.
New!!: Primary immunodeficiency and IL2RA · See more »
Immune system
The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease.
New!!: Primary immunodeficiency and Immune system · See more »
Immunodeficiency
Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent.
New!!: Primary immunodeficiency and Immunodeficiency · See more »
Immunoglobulin A
Immunoglobulin A (IgA, also referred to as sIgA in its secretory form) is an antibody that plays a crucial role in the immune function of mucous membranes.
New!!: Primary immunodeficiency and Immunoglobulin A · See more »
Immunoglobulin G
Immunoglobulin G (IgG) is a type of antibody.
New!!: Primary immunodeficiency and Immunoglobulin G · See more »
Immunoglobulin heavy chain
The immunoglobulin heavy chain (IgH) is the large polypeptide subunit of an antibody (immunoglobulin).
New!!: Primary immunodeficiency and Immunoglobulin heavy chain · See more »
Immunoglobulin light chain
The immunoglobulin light chain is the small polypeptide subunit of an antibody (immunoglobulin).
New!!: Primary immunodeficiency and Immunoglobulin light chain · See more »
Immunoglobulin M
Immunoglobulin M (IgM) is one of several forms of antibody that are produced by vertebrates.
New!!: Primary immunodeficiency and Immunoglobulin M · See more »
Immunoglobulin therapy
Immunoglobulin therapy, also known as normal human immunoglobulin (NHIG), is the use of a mixture of antibodies (immunoglobulins) to treat a number of health conditions.
New!!: Primary immunodeficiency and Immunoglobulin therapy · See more »
Immunosuppression
Immunosuppression is a reduction of the activation or efficacy of the immune system.
New!!: Primary immunodeficiency and Immunosuppression · See more »
Infection
Infection is the invasion of an organism's body tissues by disease-causing agents, their multiplication, and the reaction of host tissues to the infectious agents and the toxins they produce.
New!!: Primary immunodeficiency and Infection · See more »
Innate immune system
The innate immune system, also known as the non-specific immune system or in-born immunity system, is an important subsystem of the overall immune system that comprises the cells and mechanisms involved in the defense of the host from infection by other organisms.
New!!: Primary immunodeficiency and Innate immune system · See more »
Interferon-gamma receptor
The interferon-gamma receptor (IFNGR) is a receptor that binds interferon-γ, the sole member of interferon type II.
New!!: Primary immunodeficiency and Interferon-gamma receptor · See more »
Interleukin 12
Interleukin 12 (IL-12) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, and human B-lymphoblastoid cells (NC-37) in response to antigenic stimulation.
New!!: Primary immunodeficiency and Interleukin 12 · See more »
Interleukin 23 subunit alpha
Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene.
New!!: Primary immunodeficiency and Interleukin 23 subunit alpha · See more »
Interleukin 7
Interleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene.
New!!: Primary immunodeficiency and Interleukin 7 · See more »
Interleukin-12 subunit beta
Subunit beta of interleukin 12 (also known as IL-12B, natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor p40, or interleukin-12 subunit p40) is a protein that in humans is encoded by the IL12B gene.
New!!: Primary immunodeficiency and Interleukin-12 subunit beta · See more »
International Union of Immunological Societies
The International Union of Immunological Societies (IUIS), a member of the International Council for Science, is an organization which serves as an umbrella organization for many national and regionally grouped immunological societies.
New!!: Primary immunodeficiency and International Union of Immunological Societies · See more »
IPEX syndrome
IPEX (immunodysregulation polyendocrinopathy enteropathy X-linked) syndrome is a rare disease linked to the dysfunction of the transcription factor FOXP3, widely considered to be the master regulator of the regulatory T cell lineage.
New!!: Primary immunodeficiency and IPEX syndrome · See more »
IRAK4
IRAK-4 (interleukin-1 receptor-associated kinase 4), in the IRAK family, is a protein kinase involved in signaling innate immune responses from Toll-like receptors.
New!!: Primary immunodeficiency and IRAK4 · See more »
Kostmann syndrome
Kostmann syndrome is a group of diseases that affect myelopoiesis, causing a congenital form of neutropenia (severe congenital neutropenia), usually without other physical malformations.
New!!: Primary immunodeficiency and Kostmann syndrome · See more »
Leukocyte adhesion deficiency
Leukocyte adhesion deficiency (LAD), is a rare autosomal recessive disorder characterized by immunodeficiency resulting in recurrent infections.
New!!: Primary immunodeficiency and Leukocyte adhesion deficiency · See more »
Lymphocyte
A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system.
New!!: Primary immunodeficiency and Lymphocyte · See more »
Lymphoma
Lymphoma is a group of blood cancers that develop from lymphocytes (a type of white blood cell).
New!!: Primary immunodeficiency and Lymphoma · See more »
Macrophage
Macrophages (big eaters, from Greek μακρός (makrós).
New!!: Primary immunodeficiency and Macrophage · See more »
Majeed syndrome
Majeed syndrome is an inherited skin disorder characterized by chronic recurrent multifocal osteomyelitis, congenital dyserythropoietic anemia and a neutrophilic dermatosis.
New!!: Primary immunodeficiency and Majeed syndrome · See more »
MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 is a protein that in humans is encoded by the MALT1 gene.
New!!: Primary immunodeficiency and MALT1 · See more »
Mannan-binding lectin
Mannose-binding lectin (MBL), also called mannose-binding protein or mannan-binding protein (MBP), is a lectin that is instrumental in innate immunity via the lectin pathway.
New!!: Primary immunodeficiency and Mannan-binding lectin · See more »
MASP2 (protein)
Mannan-binding lectin serine protease 2 also known as mannose-binding protein-associated serine protease 2 (MASP-2) is an enzyme that in humans is encoded by the MASP2 gene.
New!!: Primary immunodeficiency and MASP2 (protein) · See more »
Membranoproliferative glomerulonephritis
Membranoproliferative glomerulonephritis ("MPGN"), also known as mesangiocapillary glomerulonephritis, is a type of glomerulonephritis caused by deposits in the kidney glomerular mesangium and basement membrane (GBM) thickening, activating complement and damaging the glomeruli.
New!!: Primary immunodeficiency and Membranoproliferative glomerulonephritis · See more »
MHC class I
MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules (the other being MHC class II) and are found on the cell surface of all nucleated cells in the bodies of jawed vertebrates.
New!!: Primary immunodeficiency and MHC class I · See more »
MHC class II
MHC class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells.
New!!: Primary immunodeficiency and MHC class II · See more »
Mitogen
A mitogen is a chemical substance that encourages a cell to commence cell division, triggering mitosis.
New!!: Primary immunodeficiency and Mitogen · See more »
Monocyte
Monocytes are a type of leukocyte, or white blood cell.
New!!: Primary immunodeficiency and Monocyte · See more »
MRE11A
Double-strand break repair protein MRE11A is a protein that in humans is encoded by the MRE11A gene.
New!!: Primary immunodeficiency and MRE11A · See more »
Muckle–Wells syndrome
Muckle–Wells syndrome (MWS), also known as urticaria-deafness-amyloidosis syndrome (UDA), is a rare autosomal dominant disease which causes sensorineural deafness and recurrent hives, and can lead to amyloidosis.
New!!: Primary immunodeficiency and Muckle–Wells syndrome · See more »
MYD88
Myeloid differentiation primary response 88 (MYD88) is a protein that, in humans, is encoded by the MYD88 gene.
New!!: Primary immunodeficiency and MYD88 · See more »
Myelodysplastic syndrome
Myelodysplastic syndromes (MDS) are a group of cancers in which immature blood cells in the bone marrow do not mature and therefore do not become healthy blood cells.
New!!: Primary immunodeficiency and Myelodysplastic syndrome · See more »
NALP3
NACHT, LRR and PYD domains-containing protein 3 (NALP3), also known as cryopyrin, is a protein that in humans is encoded by the NLRP3 gene located on the long arm of chromosome 1.
New!!: Primary immunodeficiency and NALP3 · See more »
Natural killer cell
Natural killer cells or NK cells are a type of cytotoxic lymphocyte critical to the innate immune system.
New!!: Primary immunodeficiency and Natural killer cell · See more »
Neonatal-onset multisystem inflammatory disease
Neonatal-onset multisystem inflammatory disease (abbreviated NOMID, also known as chronic infantile neurologic cutaneous and articular syndrome,James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders.. or CINCA) is a rare genetic periodic fever syndrome which causes uncontrolled inflammation in multiple parts of the body starting in the newborn period.
New!!: Primary immunodeficiency and Neonatal-onset multisystem inflammatory disease · See more »
Neutrophil cytosolic factor 1
Neutrophil cytosol factor 1, also known as p47phox, is a protein that in humans is encoded by the NCF1 gene.
New!!: Primary immunodeficiency and Neutrophil cytosolic factor 1 · See more »
Neutrophil cytosolic factor 2
Neutrophil cytosol factor 2 is a protein that in humans is encoded by the NCF2 gene.
New!!: Primary immunodeficiency and Neutrophil cytosolic factor 2 · See more »
Neutrophil elastase
Neutrophil elastase (leukocyte elastase, ELANE, ELA2, elastase 2, neutrophil, elaszym, serine elastase, subtype human leukocyte elastase (HLE)) is a serine proteinase in the same family as chymotrypsin and has broad substrate specificity.
New!!: Primary immunodeficiency and Neutrophil elastase · See more »
Neutrophil immunodeficiency syndrome
Neutrophil immunodeficiency syndrome is a condition caused by mutations in the Rac2 gene.
New!!: Primary immunodeficiency and Neutrophil immunodeficiency syndrome · See more »
Neutrophil-specific granule deficiency
Neutrophil-specific granule deficiency (SGD, previously known as lactoferrin deficiency) is a rare congenital immunodeficiency characterized by an increased risk for pyogenic infections due to defective production of specific granules and gelatinase granules in patient neutrophils.
New!!: Primary immunodeficiency and Neutrophil-specific granule deficiency · See more »
Nijmegen breakage syndrome
Nijmegen breakage syndrome (NBS), also known as Berlin breakage syndrome, ataxia telangiectasia variant 1 (AT-V1) and Seemanova syndrome, is a rare autosomal recessive congenital disorder causing chromosomal instability, probably as a result of a defect in the double Holliday junction DNA repair mechanism and/or the synthesis dependent strand annealing mechanism for repairing double strand breaks in DNA (see Homologous recombination).
New!!: Primary immunodeficiency and Nijmegen breakage syndrome · See more »
Nitro blue tetrazolium chloride
Nitro blue tetrazolium is a chemical compound composed of two tetrazole moieties.
New!!: Primary immunodeficiency and Nitro blue tetrazolium chloride · See more »
Normality (behavior)
Normality is a behavior that can be normal for an individual (intrapersonal normality) when it is consistent with the most common behaviour for that person.
New!!: Primary immunodeficiency and Normality (behavior) · See more »
Ogden Bruton
Ogden Carr Bruton (born 14 June 1908 in Mount Gilead, North Carolina; died 20 January 2003) was a pediatrician and chief of pediatrics at Walter Reed Army Hospital, where he organized the first pediatric residency at this hospital.
New!!: Primary immunodeficiency and Ogden Bruton · See more »
Omenn syndrome
Omenn syndrome is an autosomal recessive severe combined immunodeficiency associated with hypomorphic missense mutations in immunologically relevant genes of T-cells (and B-cells) such as recombination activating genes (RAG1 and RAG2), IL-7 Receptor α gene (IL7Rα), DCLRE1C-Artemis, RMRP-CHH, DNA-Ligase IV, common gamma chain, WHN-FOXN1, ZAP-70 and complete DiGeorge anomaly (DiGeorge Syndrome; CHARGE).
New!!: Primary immunodeficiency and Omenn syndrome · See more »
Osteochondrodysplasia
Osteochondrodysplasia or skeletal dysplasia is a general term for a disorder of the development (dysplasia) of bone ("osteo") and cartilage ("chondro").
New!!: Primary immunodeficiency and Osteochondrodysplasia · See more »
PAPA syndrome
PAPA syndrome is an acronym for pyogenic arthritis, pyoderma gangrenosum and acne.
New!!: Primary immunodeficiency and PAPA syndrome · See more »
Papillon–Lefèvre syndrome
Papillon–Lefèvre syndrome (PLS), also known as palmoplantar keratoderma with periodontitis, is an autosomal recessive genetic disorder caused by a deficiency in cathepsin C.
New!!: Primary immunodeficiency and Papillon–Lefèvre syndrome · See more »
Paroxysmal nocturnal hemoglobinuria
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired, life-threatening disease of the blood characterized by destruction of red blood cells by the complement system, a part of the body's innate immune system.
New!!: Primary immunodeficiency and Paroxysmal nocturnal hemoglobinuria · See more »
Perforin
Perforin-1 is a protein that in humans is encoded by the PRF1 gene and the Prf1 gene in mice.
New!!: Primary immunodeficiency and Perforin · See more »
Periodic fever syndrome
Periodic fever syndromes (also known as autoinflammatory diseases or autoinflammatory syndromes) are a set of disorders characterized by recurrent episodes of systemic and organ-specific inflammation.
New!!: Primary immunodeficiency and Periodic fever syndrome · See more »
Phagocyte
Phagocytes are cells that protect the body by ingesting harmful foreign particles, bacteria, and dead or dying cells.
New!!: Primary immunodeficiency and Phagocyte · See more »
Phagocytosis
In cell biology, phagocytosis is the process by which a cell—often a phagocyte or a protist—engulfs a solid particle to form an internal compartment known as a phagosome.
New!!: Primary immunodeficiency and Phagocytosis · See more »
Plasma cell
Plasma cells, also called plasma B cells, plasmocytes, plasmacytes, or effector B cells, are white blood cells that secrete large volumes of antibodies.
New!!: Primary immunodeficiency and Plasma cell · See more »
Properdin
Properdin is the only known positive regulator of complement activation that stabilizes the alternative pathway convertases.
New!!: Primary immunodeficiency and Properdin · See more »
PTPRC
Protein tyrosine phosphatase, receptor type, C also known as PTPRC is an enzyme that, in humans, is encoded by the PTPRC gene.
New!!: Primary immunodeficiency and PTPRC · See more »
Pulmonary alveolar proteinosis
Pulmonary alveolar proteinosis (PAP) is a group of rare lung disorders characterized by abnormal accumulation of surfactant-derived lipoprotein compounds within the alveoli of the lung.
New!!: Primary immunodeficiency and Pulmonary alveolar proteinosis · See more »
Purine nucleoside phosphorylase deficiency
Purine nucleoside phosphorylase deficiency, often called PNP-deficiency, is a rare autosomal recessive metabolic disorder which results in immunodeficiency.
New!!: Primary immunodeficiency and Purine nucleoside phosphorylase deficiency · See more »
Pus
Pus is an exudate, typically white-yellow, yellow, or yellow-brown, formed at the site of inflammation during bacterial or fungal infection.
New!!: Primary immunodeficiency and Pus · See more »
RAC2
Rac2 (Ras-related C3 botulinum toxin substrate 2) is a small (~21 kDa) signaling G protein (to be specific, a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases.
New!!: Primary immunodeficiency and RAC2 · See more »
Recombination-activating gene
The recombination-activating genes (RAGs) encode enzymes that play an important role in the rearrangement and recombination of the genes of immunoglobulin and T cell receptor molecules, however there is no evidence to suggest the developing T cells can undergo receptor editing in the same way that B cells do.
New!!: Primary immunodeficiency and Recombination-activating gene · See more »
Reticular dysgenesis
Reticular dysgenesis (RD) is a rare, inherited autosomal recessive disease that results in immunodeficiency.
New!!: Primary immunodeficiency and Reticular dysgenesis · See more »
Selective immunoglobulin A deficiency
Selective immunoglobulin A (IgA) deficiency (SIgAD) is a genetic immunodeficiency, a type of hypogammaglobulinemia.
New!!: Primary immunodeficiency and Selective immunoglobulin A deficiency · See more »
Severe combined immunodeficiency
Severe combined immunodeficiency, SCID, also known as alymphocytosis, Glanzmann–Riniker syndrome, severe mixed immunodeficiency syndrome, and thymic alymphoplasia, is a rare genetic disorder characterized by the disturbed development of functional T cells and B cells caused by numerous genetic mutations that result in heterogeneous clinical presentations.
New!!: Primary immunodeficiency and Severe combined immunodeficiency · See more »
Shwachman–Diamond syndrome
Shwachman–Diamond syndrome (SDS), or Shwachman–Bodian–Diamond syndrome, is a rare congenital disorder characterized by exocrine pancreatic insufficiency, bone marrow dysfunction, skeletal abnormalities and short stature.
New!!: Primary immunodeficiency and Shwachman–Diamond syndrome · See more »
Skin
Skin is the soft outer tissue covering vertebrates.
New!!: Primary immunodeficiency and Skin · See more »
STAT1
Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene.
New!!: Primary immunodeficiency and STAT1 · See more »
STAT5B
Signal transducer and activator of transcription 5B is a protein that in humans is encoded by the STAT5B gene.
New!!: Primary immunodeficiency and STAT5B · See more »
Syntaxin
Syntaxins are a family of membrane integrated Q-SNARE proteins participating in exocytosis.
New!!: Primary immunodeficiency and Syntaxin · See more »
T cell
A T cell, or T lymphocyte, is a type of lymphocyte (a subtype of white blood cell) that plays a central role in cell-mediated immunity.
New!!: Primary immunodeficiency and T cell · See more »
Thymoma with immunodeficiency
Thymoma with immunodeficiency (also known as "Good syndrome") is a condition that occurs in adults in whom hypogammaglobulinemia, deficient cell-mediated immunity, and benign thymoma may develop almost simultaneously.
New!!: Primary immunodeficiency and Thymoma with immunodeficiency · See more »
Thymus
The thymus is a specialized primary lymphoid organ of the immune system.
New!!: Primary immunodeficiency and Thymus · See more »
TNF receptor associated periodic syndrome
TNF receptor associated periodic syndrome (TRAPSsubscription needed) is a periodic fever syndrome associated with mutations in a receptor for the molecule tumor necrosis factor (TNF) that is inheritable in an autosomal dominant manner.
New!!: Primary immunodeficiency and TNF receptor associated periodic syndrome · See more »
TNF receptor superfamily
The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis factors (TNFs) via an extracellular cysteine-rich domain.
New!!: Primary immunodeficiency and TNF receptor superfamily · See more »
Transient hypogammaglobulinemia of infancy
Transient hypogammaglobulinemia of infancy is a form of hypogammaglobulinemia appearing after birth, leading to a reduction in the level of IgG, and also sometimes IgA and IgM.
New!!: Primary immunodeficiency and Transient hypogammaglobulinemia of infancy · See more »
Trypanosomiasis
Trypanosomiasis or trypanosomosis is the name of several diseases in vertebrates caused by parasitic protozoan trypanosomes of the genus Trypanosoma.
New!!: Primary immunodeficiency and Trypanosomiasis · See more »
UNC13D
Protein unc-13 homolog D, also known as munc13-4, is a protein that in humans is encoded by the UNC13D gene.
New!!: Primary immunodeficiency and UNC13D · See more »
WHIM syndrome
WHIM Syndrome (or Warts, Hypogammaglobulinemia, Immunodeficiency, and Myelokathexis syndrome) is a rare congenital immunodeficiency disorder characterized by chronic noncyclic neutropenia.
New!!: Primary immunodeficiency and WHIM syndrome · See more »
Wiskott–Aldrich syndrome
Wiskott–Aldrich syndrome (WAS) is a rare X-linked recessive disease characterized by eczema, thrombocytopenia (low platelet count), immune deficiency, and bloody diarrhea (secondary to the thrombocytopenia).
New!!: Primary immunodeficiency and Wiskott–Aldrich syndrome · See more »
X-linked agammaglobulinemia
X-linked agammaglobulinemia (XLA) is a rare genetic disorder discovered in 1952 that affects the body's ability to fight infection.
New!!: Primary immunodeficiency and X-linked agammaglobulinemia · See more »
X-linked lymphoproliferative disease
X-linked lymphoproliferative disease (also known as "Duncan's disease" or "Purtilo syndrome") is a lymphoproliferative disorder.
New!!: Primary immunodeficiency and X-linked lymphoproliferative disease · See more »
ZAP70
ZAP-70 (Zeta-chain-associated protein kinase 70) is a protein normally expressed near the surface membrane of T cells and natural killer cells.
New!!: Primary immunodeficiency and ZAP70 · See more »
Redirects here:
Immune disease, Primary Immune Deficiency, Primary immmune deficiencies, Primary immune deficiencies, Primary immune deficiency, Primary immunodeficiencies, Primary immunodeficiency disease, Primary immunodeficiency diseases, T cell immunodeficiency primary.
References
[1] https://en.wikipedia.org/wiki/Primary_immunodeficiency
