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20 relations: Adenocarcinoma, Angiogenesis inhibitor, Antimetabolite, Catabolism, Chemotherapy, Colorectal cancer, Competitive inhibition, Dihydropyrimidine dehydrogenase, Fluorouracil, Folinic acid, Hypoxia-inducible factors, Liver cancer, Merck Serono, Metastasis, National Institute for Health and Care Excellence, Nucleobase, Pancreatic cancer, Tegafur, Tetrahydrofuran, Uracil.
Adenocarcinoma
Adenocarcinoma (plural adenocarcinomas or adenocarcinomata) is a type of cancerous tumor that can occur in several parts of the body.
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Angiogenesis inhibitor
An angiogenesis inhibitor is a substance that inhibits the growth of new blood vessels (angiogenesis).
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Antimetabolite
An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism.
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Catabolism
Catabolism (from Greek κάτω kato, "downward" and βάλλειν ballein, "to throw") is the set of metabolic pathways that breaks down molecules into smaller units that are either oxidized to release energy or used in other anabolic reactions.
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.
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Colorectal cancer
Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from the colon or rectum (parts of the large intestine).
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Competitive inhibition
Competitive inhibition is a form of enzyme inhibition where binding of an inhibitor prevents binding of the target molecule of the enzyme, also known as the substrate.
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Dihydropyrimidine dehydrogenase
Dihydropyrimidine dehydrogenase (DPD) is an enzyme that is involved in pyrimidine degradation.
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Fluorouracil
Fluorouracil (5-FU), sold under the brand name Adrucil among others, is a medication used to treat cancer.
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Folinic acid
Folinic acid, also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate and pyrimethamine.
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Hypoxia-inducible factors
Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia.
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Liver cancer
Liver cancer, also known as hepatic cancer and primary hepatic cancer, is cancer that starts in the liver.
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Merck Serono
Merck Serono (EMD Serono in the United States and Canada) is a pharmaceutical company headquartered in Darmstadt, Germany, and a brand and division of Merck focused on biopharmaceuticals.
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Metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.
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National Institute for Health and Care Excellence
The National Institute for Health and Care Excellence (NICE) is an executive non-departmental public body of the Department of Health in the United Kingdom, which publishes guidelines in four areas.
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Nucleobase
Nucleobases, also known as nitrogenous bases or often simply bases, are nitrogen-containing biological compounds that form nucleosides, which in turn are components of nucleotides, with all of these monomers constituting the basic building blocks of nucleic acids.
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Pancreatic cancer
Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass.
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Tegafur
Tegafur (INN, BAN, USAN) is a chemotherapeutic prodrug of 5-fluorouracil (5-FU) used in the treatment of cancers.
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Tetrahydrofuran
Tetrahydrofuran (THF) is an organic compound with the formula (CH2)4O.
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Uracil
Uracil (U) is one of the four nucleobases in the nucleic acid of RNA that are represented by the letters A, G, C and U. The others are adenine (A), cytosine (C), and guanine (G).
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