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Telapristone

Index Telapristone

Telapristone, as telapristone acetate (proposed brand names Proellex, Progenta; former code name CDB-4124), is a synthetic, steroidal selective progesterone receptor modulator (SPRM) related to mifepristone which is under development by Repros Therapeutics for the treatment of breast cancer, endometriosis, and uterine fibroids. [1]

15 relations: Aglepristone, Antiglucocorticoid, Breast cancer, Clinical trial, Endometriosis, Lilopristone, Mifepristone, National Institutes of Health, Onapristone, Organic compound, Phases of clinical research, Selective progesterone receptor modulator, Steroid, Toripristone, Uterine fibroid.

Aglepristone

Aglepristone (brand name Alizine; former developmental code names RU-46534, RU-534) is a synthetic, steroidal antiprogestogen related to mifepristone which is marketed by Virbac in several European countries for use in veterinary medicine.

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Antiglucocorticoid

An antiglucocorticoid is a drug which reduces glucocorticoid activity in the body.

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Breast cancer

Breast cancer is cancer that develops from breast tissue.

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Clinical trial

Clinical trials are experiments or observations done in clinical research.

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Endometriosis

Endometriosis is a condition in which the endometrium, the layer of tissue that normally covers the inside of the uterus, grows outside of it.

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Lilopristone

Lilopristone (INN) (developmental code names ZK-98734, ZK-734) is a synthetic, steroidal antiprogestogen with additional antiglucocorticoid activity which was developed by Schering and was patented in 1985.

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Mifepristone

Mifepristone, also known as RU-486, is a medication typically used in combination with misoprostol, to bring about an abortion.

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National Institutes of Health

The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.

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Onapristone

Onapristone (INN) (developmental code names ZK-89299, ZK-299) is a synthetic, steroidal antiprogestogen with additional antiglucocorticoid activity which was developed by Schering and described in 1984 but was never marketed.

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Organic compound

In chemistry, an organic compound is generally any chemical compound that contains carbon.

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Phases of clinical research

The phases of clinical research are the steps in which scientists do experiments with a health intervention in an attempt to find enough evidence for a process which would be useful as a medical treatment.

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Selective progesterone receptor modulator

A selective progesterone receptor modulator (SPRM) is an agent that acts on the progesterone receptor.

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Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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Toripristone

Toripristone (INN) (developmental code name RU-40555) is a synthetic, steroidal antiglucocorticoid as well as antiprogestogen which was never marketed.

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Uterine fibroid

Uterine fibroids, also known as uterine leiomyomas or fibroids, are benign smooth muscle tumors of the uterus.

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Redirects here:

C31H39NO5, CDB-4124, Proellex, Progenta, Telapristone acetate.

References

[1] https://en.wikipedia.org/wiki/Telapristone

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