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Tetrahydrodeoxycorticosterone

Index Tetrahydrodeoxycorticosterone

Tetrahydrodeoxycorticosterone (abbreviated as THDOC; 3α,21-dihydroxy-5α-pregnan-20-one), also referred to as allotetrahydrocorticosterone, is an endogenous neurosteroid. [1]

Table of Contents

  1. 21 relations: Allopregnanolone, Allosteric modulator, Anticonvulsant, Anxiety, Anxiolytic, Catamenial epilepsy, Deoxycorticosterone, Depression (mood), Dihydrodeoxycorticosterone, Endogeny (biology), Epilepsy, GABAA receptor, Menstruation, Neurosteroid, Pregnancy, Premenstrual syndrome, Sedative, SRD5A1, Stress (biology), Tetrahydrocorticosterone, 3α-Hydroxysteroid dehydrogenase.

  2. GABAA-rho receptor negative allosteric modulators

Allopregnanolone

Allopregnanolone is a naturally occurring neurosteroid which is made in the body from the hormone progesterone. Tetrahydrodeoxycorticosterone and Allopregnanolone are Anticonvulsants, GABAA receptor positive allosteric modulators, neurosteroids and Pregnanes.

See Tetrahydrodeoxycorticosterone and Allopregnanolone

Allosteric modulator

In pharmacology and biochemistry, allosteric modulators are a group of substances that bind to a receptor to change that receptor's response to stimuli.

See Tetrahydrodeoxycorticosterone and Allosteric modulator

Anticonvulsant

Anticonvulsants (also known as antiepileptic drugs, antiseizure drugs, or anti-seizure medications (ASM)) are a diverse group of pharmacological agents used in the treatment of epileptic seizures. Tetrahydrodeoxycorticosterone and Anticonvulsant are Anticonvulsants.

See Tetrahydrodeoxycorticosterone and Anticonvulsant

Anxiety

Anxiety is an emotion which is characterised by an unpleasant state of inner turmoil and includes feelings of dread over anticipated events.

See Tetrahydrodeoxycorticosterone and Anxiety

Anxiolytic

An anxiolytic (also antipanic or anti-anxiety agent) is a medication or other intervention that reduces anxiety.

See Tetrahydrodeoxycorticosterone and Anxiolytic

Catamenial epilepsy

Catamenial epilepsy is a form of epilepsy in women where seizures are exacerbated during certain phases of the menstrual cycle.

See Tetrahydrodeoxycorticosterone and Catamenial epilepsy

Deoxycorticosterone

Deoxycorticosterone (DOC), or desoxycorticosterone, may refer to. Tetrahydrodeoxycorticosterone and Deoxycorticosterone are Pregnanes.

See Tetrahydrodeoxycorticosterone and Deoxycorticosterone

Depression (mood)

Depression is a mental state of low mood and aversion to activity.

See Tetrahydrodeoxycorticosterone and Depression (mood)

Dihydrodeoxycorticosterone

5α-Dihydrodeoxycorticosterone (abbreviated as DHDOC), also known as 21-hydroxy-5α-pregnan-20-one, is an endogenous progestogen and neurosteroid. Tetrahydrodeoxycorticosterone and Dihydrodeoxycorticosterone are GABAA receptor positive allosteric modulators, neurosteroids and Pregnanes.

See Tetrahydrodeoxycorticosterone and Dihydrodeoxycorticosterone

Endogeny (biology)

Endogenous substances and processes are those that originate from within a living system such as an organism, tissue, or cell.

See Tetrahydrodeoxycorticosterone and Endogeny (biology)

Epilepsy

Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures.

See Tetrahydrodeoxycorticosterone and Epilepsy

GABAA receptor

The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.

See Tetrahydrodeoxycorticosterone and GABAA receptor

Menstruation

Menstruation (also known as a period, among other colloquial terms) is the regular discharge of blood and mucosal tissue from the inner lining of the uterus through the vagina.

See Tetrahydrodeoxycorticosterone and Menstruation

Neurosteroid

Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors. Tetrahydrodeoxycorticosterone and Neurosteroid are neurosteroids.

See Tetrahydrodeoxycorticosterone and Neurosteroid

Pregnancy

Pregnancy is the time during which one or more offspring develops (gestates) inside a woman's uterus (womb).

See Tetrahydrodeoxycorticosterone and Pregnancy

Premenstrual syndrome

Premenstrual syndrome (PMS) is a disruptive set of emotional and physical symptoms that regularly occur in the one to two weeks before the start of each menstrual period.

See Tetrahydrodeoxycorticosterone and Premenstrual syndrome

Sedative

A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement.

See Tetrahydrodeoxycorticosterone and Sedative

SRD5A1

3-Oxo-5α-steroid 4-dehydrogenase 1 is an enzyme that in humans is encoded by the SRD5A1 gene.

See Tetrahydrodeoxycorticosterone and SRD5A1

Stress (biology)

Stress, whether physiological, biological or psychological, is an organism's response to a stressor such as an environmental condition.

See Tetrahydrodeoxycorticosterone and Stress (biology)

Tetrahydrocorticosterone

3α,5α-Tetrahydrocorticosterone (3α,5α-THB), or simply tetrahydrocorticosterone (THB or THCC), is an endogenous glucocorticoid hormone. Tetrahydrodeoxycorticosterone and tetrahydrocorticosterone are Pregnanes and steroid stubs.

See Tetrahydrodeoxycorticosterone and Tetrahydrocorticosterone

3α-Hydroxysteroid dehydrogenase

3α-Hydroxysteroid dehydrogenase (3α-HSD) is an enzyme (1.1.1.50) that plays a role in the metabolism of steroids and non-steroidal compounds in humans and other species, such as bacteria, fungi, plants, and so on.

See Tetrahydrodeoxycorticosterone and 3α-Hydroxysteroid dehydrogenase

See also

GABAA-rho receptor negative allosteric modulators

References

[1] https://en.wikipedia.org/wiki/Tetrahydrodeoxycorticosterone

Also known as Allotetrahydrodeoxycorticosterone, Allotetrahydroxycorticosterone, THDOC.