51 relations: Agonist, Anabolic steroid, Anabolism, Androgen, Androgen receptor, Bay Area Laboratory Co-operative, Clandestine chemistry, Derivative (chemistry), Designer drug, Desoxymethyltestosterone, Dihydrotestosterone, Don Catlin, Dwain Chambers, Endometriosis, Estrane, Estrogen (medication), Ethyl group, Ethynyl, Food and Drug Administration, Gestrinone, Glucocorticoid, Hirsutism, Hydrogenation, Immunosuppression, Infertility, Intramuscular injection, Jason Giambi, Ligand (biochemistry), Marion Jones, Mass spectrometry, Metribolone, Molecular modification, Nandrolone, Norboletone, Norethandrolone, Norethisterone, Oral administration, Organic compound, Patrick Arnold, Progesterone receptor, Progestogen, RU-2309, Steroid, The Washington Post, Trenbolone, Trevor Graham, United States Anti-Doping Agency, University of Bristol, USA Today, 17α-Alkylated anabolic steroid, ..., 2000 Summer Olympics. Expand index (1 more) » « Shrink index
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.
Anabolism (from ἁνά, "upward" and βάλλειν, "to throw") is the set of metabolic pathways that construct molecules from smaller units.
An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
The Bay Area Laboratory Co-Operative (BALCO) (1984–2003) was an American company led by founder and owner Victor Conte.
Clandestine chemistry is chemistry carried out in secret, and particularly in illegal drug laboratories.
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests.
Desoxymethyltestosterone (DMT), known by the nicknames Madol and Pheraplex, is a synthetic and orally active anabolic–androgenic steroid (AAS) and a 17α-methylated derivative of dihydrotestosterone (DHT) which was never marketed for medical use.
Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or stanolone, is an endogenous androgen sex steroid and hormone.
Don H. Catlin (born June 4, 1938) is an anti-doping scientist and one of the founders of modern drug-testing in sport.
Dwain Anthony Chambers (born 5 April 1978) is a retired British track sprinter.
Endometriosis is a condition in which the endometrium, the layer of tissue that normally covers the inside of the uterus, grows outside of it.
Estrane is a C18 steroid derivative, with a gonane core.
An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
In chemistry, an ethyl group is an alkyl substituent derived from ethane (C2H6).
In organic chemistry, the term ethynyl designates.
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
Gestrinone, sold under the brand names Dimetrose and Nemestran among others, is a medication which is used in the treatment of endometriosis.
Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones.
Hirsutism is excessive body hair in men and women on parts of the body where hair is normally absent or minimal, such as on the chin or chest in particular, or the face or body in general.
Hydrogenation – to treat with hydrogen – is a chemical reaction between molecular hydrogen (H2) and another compound or element, usually in the presence of a catalyst such as nickel, palladium or platinum.
Immunosuppression is a reduction of the activation or efficacy of the immune system.
Infertility is the inability of a person, animal or plant to reproduce by natural means.
Intramuscular (also IM or im) injection is the injection of a substance directly into muscle.
Jason Gilbert Giambi (born January 8, 1971) is an American former professional baseball first baseman and designated hitter.
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
Marion Lois Jones (born October 12, 1975), also known as Marion Jones-Thompson, is an American former world champion track and field athlete and a former professional basketball player for Tulsa Shock in the WNBA.
Mass spectrometry (MS) is an analytical technique that ionizes chemical species and sorts the ions based on their mass-to-charge ratio.
Metribolone (developmental code name R1881), also known as methyltrienolone, is a synthetic and orally active anabolic–androgenic steroid (AAS) and a 17α-alkylated nandrolone (19-nortestosterone) derivative which was never marketed for medical use but has been widely used in scientific research as a hot ligand in androgen receptor (AR) ligand binding assays (LBAs) and as a photoaffinity label for the AR.
Molecular modification is chemical alteration of a known and previously characterized lead compound for the purpose of enhancing its usefulness as a drug.
Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin).
Norboletone (former proposed brand name Genabol), or norbolethone, is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never marketed.
Norethandrolone, sold under the brand names Nilevar and Pronabol among others, is an androgen and anabolic steroid (AAS) medication which has been used to promote muscle growth and to treat severe burns, physical trauma, and aplastic anemia but has mostly been discontinued.
Norethisterone, also known as norethindrone and sold under the brand names Aygestin and Primolut N among many others, is a progestin medication which is used in birth control pills, menopausal hormone therapy, and for the treatment of gynecological disorders.
In chemistry, an organic compound is generally any chemical compound that contains carbon.
Patrick Arnold is an American organic chemist known for introducing androstenedione, 1-androstenediol, and methylhexanamine into the dietary supplement market, and for creating the designer steroid tetrahydrogestrinone, also known as THG and "the clear".
The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.
Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).
RU-2309, also known as 18-methylmetribolone, δ9,11-17α,18-dimethyl-19-nortestosterone, or 17α,18-dimethylestr-4,9,11-trien-17β-ol-3-one, is a 17α-alkylated androgen/anabolic steroid (AAS) of the 19-nortestosterone group which was never marketed.
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
The Washington Post is a major American daily newspaper founded on December 6, 1877.
Trenbolone is an androgen and anabolic steroid (AAS) of the nandrolone group which itself was never marketed.
Trevor Graham (born 20 August 1963) is a Jamaican-born former sprinter and athletics coach, based in the United States.
The United States Anti-Doping Agency (USADA) is a non-profit, non-governmental 501(c)(3) organization and the national anti-doping organization (NADO) for the United States.
The University of Bristol (simply referred to as Bristol University and abbreviated as Bris. in post-nominal letters, or UoB) is a red brick research university located in Bristol, United Kingdom.
USA Today is an internationally distributed American daily, middle-market newspaper that serves as the flagship publication of its owner, the Gannett Company.
A 17α-alkylated anabolic steroid is a synthetic anabolic–androgenic steroid (AAS) that features an alkyl group, specifically a methyl or ethyl group, at the C17α position.
The 2000 Summer Olympic Games, officially known as the Games of the XXVII Olympiad and commonly known as Sydney 2000 or the Millennium Olympic Games/Games of the New Millennium, were an international multi-sport event which was held between 15 September and 1 October 2000 in Sydney, New South Wales, Australia.