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110 relations: ADAMTS13, Alport syndrome, Antibody, Anticoagulant, Antiphospholipid syndrome, Aplastic anemia, Argatroban, Bernard–Soulier syndrome, Bivalirudin, Blood, Bone marrow examination, Breastfeeding, Bruise, Candida (fungus), Carboplatin, Complete blood count, Congenital amegakaryocytic thrombocytopenia, Corticosteroid, Cytomegalovirus, Dehydration, Dengue fever, Direct thrombin inhibitor, Disseminated intravascular coagulation, Ecchymosis, Endogeny (biology), Enterococcus, Erythrocyte sedimentation rate, Escherichia coli, Ethylenediaminetetraacetic acid, Fanconi anemia, Folate, Folate deficiency, Fondaparinux, Gaucher's disease, Gram-negative bacteria, Gray platelet syndrome, Gums, H2 antagonist, Haemophilus influenzae, Hematology, Hemolytic anemia, Hemolytic-uremic syndrome, HIV, Immune thrombocytopenic purpura, Immunosuppression, Interferon, Interleukin 11, Isotretinoin, Kidney failure, Klebsiella pneumoniae, ..., Lepirudin, Leptospirosis, Leukemia, Listeria monocytogenes, Lithium carbonate, Liver, Liver failure, Liver function tests, Lyme disease, May–Hegglin anomaly, Megakaryocyte, Methotrexate, Myelodysplastic syndrome, Necrotizing enterocolitis, Neonatal alloimmune thrombocytopenia, Niacin, Nosebleed, Panobinostat, Paroxysmal nocturnal hemoglobinuria, Pathogenic bacteria, Percentile, Petechia, Plasmapheresis, Platelet, Platelet transfusion, Plateletpheresis, Polymerase chain reaction, Post-transfusion purpura, Protease, Protein, Proton-pump inhibitor, Pseudomonas aeruginosa, Purpura, Red blood cell, Relapse, Renal function, Romiplostim, Rubella virus, Sepsis, Snakebite, Splenectomy, Splenomegaly, Staphylococcus, Streptococcus agalactiae, Systemic lupus erythematosus, TAR syndrome, Thrombopoietin, Thrombosis, Thrombotic thrombocytopenic purpura, Toxoplasma gondii, Valproate, Virus, Vitamin B12, Vitamin B12 deficiency, Von Willebrand factor, Warfarin, White blood cell, Wiskott–Aldrich syndrome, Yersinia enterocolitica, Zika virus. Expand index (60 more) »
ADAMTS13
ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13)—also known as von Willebrand factor-cleaving protease (VWFCP)—is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein involved in blood clotting.
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Alport syndrome
Alport syndrome is a genetic disorder affecting around 1 in 50,000 children, characterized by glomerulonephritis, end-stage kidney disease, and hearing loss.
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Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.
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Anticoagulant
Anticoagulants, commonly referred to as blood thinners, are chemical substances that prevent or reduce coagulation of blood, prolonging the clotting time.
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Antiphospholipid syndrome
Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by antiphospholipid antibodies.
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Aplastic anemia
Aplastic anaemia is a rare disease in which the bone marrow and the hematopoietic stem cells that reside there are damaged.
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Argatroban
Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor.
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Bernard–Soulier syndrome
Bernard–Soulier syndrome (BSS), also called hemorrhagiparous thrombocytic dystrophy, is a rare autosomal recessive bleeding disorder that causes a deficiency of glycoprotein Ib (GpIb), the receptor for von Willebrand factor.
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Bivalirudin
Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a direct thrombin inhibitor (DTI).
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Blood
Blood is a body fluid in humans and other animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells.
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Bone marrow examination
Bone marrow examination refers to the pathologic analysis of samples of bone marrow obtained by bone marrow biopsy (often called a trephine biopsy) and bone marrow aspiration.
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Breastfeeding
Breastfeeding, also known as nursing, is the feeding of babies and young children with milk from a woman's breast.
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Bruise
A contusion, commonly known as a bruise, is a type of hematoma of tissue in which capillaries and sometimes venules are damaged by trauma, allowing blood to seep, hemorrhage, or extravasate into the surrounding interstitial tissues.
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Candida (fungus)
Candida is a genus of yeasts and is the most common cause of fungal infections worldwide.
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Carboplatin
Carboplatin, sold under the trade name Paraplatin among others, is a chemotherapy medication used to treat a number of forms of cancer.
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Complete blood count
A complete blood count (CBC), also known as a complete blood cell count, full blood count (FBC), or full blood exam (FBE), is a blood panel requested by a doctor or other medical professional that gives information about the cells in a patient's blood, such as the cell count for each cell type and the concentrations of various proteins and minerals.
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Congenital amegakaryocytic thrombocytopenia
Congenital amegakaryocytic thrombocytopenia (CAMT) is a rare inherited disorder.
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Corticosteroid
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.
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Cytomegalovirus
Cytomegalovirus (CMV) (from the Greek cyto-, "cell", and megalo-, "large") is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Betaherpesvirinae.
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Dehydration
In physiology, dehydration is a deficit of total body water, with an accompanying disruption of metabolic processes.
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Dengue fever
Dengue fever is a mosquito-borne tropical disease caused by the dengue virus.
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Direct thrombin inhibitor
Direct thrombin inhibitors (DTIs) are a class of medication that act as anticoagulants (delaying blood clotting) by directly inhibiting the enzyme thrombin (factor IIa).
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Disseminated intravascular coagulation
Disseminated intravascular coagulation (DIC) is a condition in which blood clots form throughout the body, blocking small blood vessels.
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Ecchymosis
An ecchymosis is a subcutaneous spot of bleeding (from extravasation of blood) with diameter larger than.
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Endogeny (biology)
Endogenous substances and processes are those that originate from within an organism, tissue, or cell.
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Enterococcus
Enterococcus is a large genus of lactic acid bacteria of the phylum Firmicutes.
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Erythrocyte sedimentation rate
The erythrocyte sedimentation rate (ESR or sed rate) is the rate at which red blood cells sediment in a period of one hour.
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Escherichia coli
Escherichia coli (also known as E. coli) is a Gram-negative, facultatively anaerobic, rod-shaped, coliform bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms).
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Ethylenediaminetetraacetic acid
Ethylenediaminetetraacetic acid (EDTA), also known by several other names, is a chemical originating in multiseasonal plants with dormancy stages as a lipidopreservative which helps to develop the stem, currently used for both industrial and medical purposes.
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Fanconi anemia
Fanconi anaemia (FA) is a rare genetic disease resulting in impaired response to DNA damage.
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Folate
Folate, distinct forms of which are known as folic acid, folacin, and vitamin B9, is one of the B vitamins.
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Folate deficiency
Folate deficiency is a low level of folic acid and derivatives in the body.
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Fondaparinux
Fondaparinux (trade name Arixtra) is an anticoagulant medication chemically related to low molecular weight heparins.
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Gaucher's disease
Gaucher's disease or Gaucher disease (GD) is a genetic disorder in which glucocerebroside (a sphingolipid, also known as glucosylceramide) accumulates in cells and certain organs.
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Gram-negative bacteria
Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the gram-staining method of bacterial differentiation.
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Gray platelet syndrome
Gray platelet syndrome (GPS), or platelet alpha-granule deficiency, is a rare congenital autosomal recessive bleeding disorder caused by a reduction or absence of alpha-granules in blood platelets, and the release of proteins normally contained in these granules into the marrow, causing myelofibrosis.
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Gums
The gums or gingiva (plural: gingivae), consist of the mucosal tissue that lies over the mandible and maxilla inside the mouth.
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H2 antagonist
H2 antagonists, sometimes referred to as H2RA and also called H2 blockers, are a class of medications that block the action of histamine at the histamine H2 receptors of the parietal cells in the stomach.
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Haemophilus influenzae
Haemophilus influenzae (formerly called Pfeiffer's bacillus or Bacillus influenzae) is a Gram-negative, coccobacillary, facultatively anaerobic pathogenic bacterium belonging to the Pasteurellaceae family.
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Hematology
Hematology, also spelled haematology, is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood.
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Hemolytic anemia
Hemolytic anemia or haemolytic anaemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular, but usually in the spleen).
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Hemolytic-uremic syndrome
Hemolytic-uremic syndrome (HUS) is a disease characterized by a triad of hemolytic anemia (anemia caused by destruction of red blood cells), acute kidney failure (uremia), and a low platelet count (thrombocytopenia).
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HIV
The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS).
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Immune thrombocytopenic purpura
Immune thrombocytopenia (ITP) is a type of thrombocytopenic purpura defined as isolated low platelet count (thrombocytopenia) with normal bone marrow and the absence of other causes of thrombocytopenia.
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Immunosuppression
Immunosuppression is a reduction of the activation or efficacy of the immune system.
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Interferon
Interferons (IFNs) are a group of signaling proteins made and released by host cells in response to the presence of several pathogens, such as viruses, bacteria, parasites, and also tumor cells.
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Interleukin 11
Interleukin 11 (IL-11) is a protein that in humans is encoded by the IL11 gene.
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Isotretinoin
Isotretinoin, also known as 13-cis-retinoic acid (and colloquially referred to by its former brand name Accutane or Roaccutane), is a medication primarily used to treat severe acne.
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Kidney failure
Kidney failure, also known as end-stage kidney disease, is a medical condition in which the kidneys no longer work.
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Klebsiella pneumoniae
Klebsiella pneumoniae is a Gram-negative, non-motile, encapsulated, lactose-fermenting, facultative anaerobic, rod-shaped bacterium.
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Lepirudin
Lepirudin is an anticoagulant that functions as a direct thrombin inhibitor.
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Leptospirosis
Leptospirosis is an infection caused by corkscrew-shaped bacteria called Leptospira.
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Leukemia
Leukemia, also spelled leukaemia, is a group of cancers that usually begin in the bone marrow and result in high numbers of abnormal white blood cells.
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Listeria monocytogenes
Listeria monocytogenes is the species of pathogenic bacteria that causes the infection listeriosis.
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Lithium carbonate
No description.
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Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
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Liver failure
Liver failure or hepatic insufficiency is the inability of the liver to perform its normal synthetic and metabolic function as part of normal physiology.
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Liver function tests
Liver function tests (LFTs or LFs) are groups of blood tests that give information about the state of a patient's liver.
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Lyme disease
Lyme disease, also known as Lyme borreliosis, is an infectious disease caused by bacteria of the Borrelia type which is spread by ticks.
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May–Hegglin anomaly
May–Hegglin anomaly (MHA), also known as Döhle leukocyte inclusions with giant platelets and macrothrombocytopenia with leukocyte inclusions, is a rare genetic disorder of the blood platelets that causes them to be abnormally large.
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Megakaryocyte
A megakaryocyte (mega- + karyo- + -cyte, "large-nucleus cell") is a large bone marrow cell with a lobated nucleus responsible for the production of blood thrombocytes (platelets), which are necessary for normal blood clotting.
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Methotrexate
Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune system suppressant.
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Myelodysplastic syndrome
Myelodysplastic syndromes (MDS) are a group of cancers in which immature blood cells in the bone marrow do not mature and therefore do not become healthy blood cells.
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Necrotizing enterocolitis
Necrotizing enterocolitis (NEC) is a medical condition where a portion of the bowel dies.
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Neonatal alloimmune thrombocytopenia
Neonatal alloimmune thrombocytopenia (NAITP, NAIT, NATP or NAT) is a disease that affects babies in which the platelet count is decreased.
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Niacin
Niacin, also known as nicotinic acid, is an organic compound and a form of vitamin B3, an essential human nutrient.
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Nosebleed
A nosebleed, also known as epistaxis, is the common occurrence of bleeding from the nose.
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Panobinostat
Panobinostat (trade name Farydak) is a drug by Novartis for the treatment of various cancers.
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Paroxysmal nocturnal hemoglobinuria
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired, life-threatening disease of the blood characterized by destruction of red blood cells by the complement system, a part of the body's innate immune system.
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Pathogenic bacteria
Pathogenic bacteria are bacteria that can cause disease.
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Percentile
A percentile (or a centile) is a measure used in statistics indicating the value below which a given percentage of observations in a group of observations fall.
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Petechia
A petechia, plural petechiae, is a small (1–2 mm) red or purple spot on the skin, caused by a minor bleed from broken capillary blood vessels.
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Plasmapheresis
Plasmapheresis (from the Greek πλάσμα—plasma, something molded, and ἀφαίρεσις—aphairesis, taking away) is the removal, treatment, and return or exchange of blood plasma or components thereof from and to the blood circulation.
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Platelet
Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.
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Platelet transfusion
Platelet transfusion, also known as platelet concentrate, is used to prevent or treat bleeding in people with either a low platelet count or poor platelet function.
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Plateletpheresis
Plateletpheresis (more accurately called thrombocytapheresis or thrombapheresis, though these names are rarely used) is the process of collecting thrombocytes, more commonly called platelets, a component of blood involved in blood clotting.
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Polymerase chain reaction
Polymerase chain reaction (PCR) is a technique used in molecular biology to amplify a single copy or a few copies of a segment of DNA across several orders of magnitude, generating thousands to millions of copies of a particular DNA sequence.
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Post-transfusion purpura
Post-transfusion purpura (PTP) is an adverse reaction to a blood transfusion or platelet transfusion that occurs when the body produces alloantibodies to the introduced platelets' antigens.
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Protease
A protease (also called a peptidase or proteinase) is an enzyme that performs proteolysis: protein catabolism by hydrolysis of peptide bonds.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Proton-pump inhibitor
Proton-pump inhibitors (PPIs) are a group of drugs whose main action is a pronounced and long-lasting reduction of stomach acid production.
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Pseudomonas aeruginosa
Pseudomonas aeruginosa is a common Gram-negative, rod-shaped bacterium that can cause disease in plants and animals, including humans.
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Purpura
Purpura is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure.
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Red blood cell
Red blood cells-- also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system.
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Relapse
In medicine, relapse or recidivism is a recurrence of a past (typically medical) condition.
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Renal function
Renal function, in nephrology, is an indication of the kidney's condition and its role in renal physiology.
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Romiplostim
Romiplostim (rINN, USAN) is a fusion protein analog of thrombopoietin, a hormone that regulates platelet production.
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Rubella virus
Rubella virus (RuV) is the pathogenic agent of the disease rubella, and is the cause of congenital rubella syndrome when infection occurs during the first weeks of pregnancy.
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Sepsis
Sepsis is a life-threatening condition that arises when the body's response to infection causes injury to its own tissues and organs.
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Snakebite
A snakebite is an injury caused by the bite of a snake, especially a venomous snake.
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Splenectomy
A splenectomy is a surgical procedure that partially or completely removes the spleen.
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Splenomegaly
Splenomegaly is an enlargement of the spleen.
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Staphylococcus
Staphylococcus (from the σταφυλή, staphylē, "grape" and κόκκος, kókkos, "granule") is a genus of Gram-positive bacteria.
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Streptococcus agalactiae
Streptococcus agalactiae (also known as group B streptococcus or GBS) is a gram-positive coccus (round bacterium) with a tendency to form chains (as reflected by the genus name Streptococcus).
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Systemic lupus erythematosus
Systemic lupus erythematosus (SLE), also known simply as lupus, is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body.
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TAR syndrome
TAR Syndrome (thrombocytopenia with absent radius) is a rare genetic disorder that is characterized by the absence of the radius bone in the forearm and a dramatically reduced platelet count.
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Thrombopoietin
Thrombopoietin (THPO) also known as megakaryocyte growth and development factor (MGDF) is a protein that in humans is encoded by the THPO gene.
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Thrombosis
Thrombosis (from Ancient Greek θρόμβωσις thrómbōsis "clotting”) is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.
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Thrombotic thrombocytopenic purpura
Thrombotic thrombocytopenic purpura (TTP) is a rare disorder of the blood-coagulation system, causing extensive microscopic clots to form in the small blood vessels throughout the body, resulting in low platelet counts.
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Toxoplasma gondii
Toxoplasma gondii is an obligate intracellular, parasitic alveolate that causes the disease toxoplasmosis.
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Valproate
Valproate (VPA), and its valproic acid, sodium valproate, and valproate semisodium forms, are medications primarily used to treat epilepsy and bipolar disorder and to prevent migraine headaches.
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Virus
A virus is a small infectious agent that replicates only inside the living cells of other organisms.
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Vitamin B12
Vitamin B12, also called cobalamin, is a water-soluble vitamin that is involved in the metabolism of every cell of the human body: it is a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism.
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Vitamin B12 deficiency
Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition of low blood levels of vitamin B12.
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Von Willebrand factor
Von Willebrand factor (vWF) is a blood glycoprotein involved in hemostasis.
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Warfarin
Warfarin, sold under the brand name Coumadin among others, is a medication that is used as an anticoagulant (blood thinner).
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White blood cell
White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.
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Wiskott–Aldrich syndrome
Wiskott–Aldrich syndrome (WAS) is a rare X-linked recessive disease characterized by eczema, thrombocytopenia (low platelet count), immune deficiency, and bloody diarrhea (secondary to the thrombocytopenia).
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Yersinia enterocolitica
Yersinia enterocolitica is a Gram-negative bacillus-shaped bacterium, belonging to the family Enterobacteriaceae.
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Zika virus
Zika virus (ZIKV) is a member of the virus family Flaviviridae.
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References
[1] https://en.wikipedia.org/wiki/Thrombocytopenia
