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Thyrotropin-releasing hormone

Index Thyrotropin-releasing hormone

Thyrotropin-releasing hormone (TRH), also called thyrotropin-releasing factor (TRF) or thyroliberin, is a releasing hormone, produced by the hypothalamus, that stimulates the release of thyrotropin (thyroid-stimulating hormone or TSH) and prolactin from the anterior pituitary. [1]

30 relations: Acromegaly, Andrew Schally, Anterior pituitary, Gastrointestinal tract, Globe, Glutamine, Hypophyseal portal system, Hypothalamic–pituitary–prolactin axis, Hypothalamus, Hypothyroidism, International nonproprietary name, Intrathecal administration, Median eminence, Medication, Nobel Prize in Physiology or Medicine, Pancreatic islets, Paraventricular nucleus of hypothalamus, Peptide hormone, Prolactin, Releasing and inhibiting hormones, Roger Guillemin, Spinocerebellar ataxia, Structural formula, Thyroid, Thyroid-stimulating hormone, Thyrotropic cell, Thyrotropin-releasing hormone receptor, TRH stimulation test, Tropic hormone, Unified atomic mass unit.

Acromegaly

Acromegaly is a disorder that results from excess growth hormone (GH) after the growth plates have closed.

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Andrew Schally

Andrzej Viktor "Andrew" Schally (born 30 November 1926) is an American endocrinologistAndrew V. Schally,, Encyclopædia Britannica.

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Anterior pituitary

A major organ of the endocrine system, the anterior pituitary (also called the adenohypophysis or pars anterior), is the glandular, anterior lobe that together with the posterior lobe (posterior pituitary, or the neurohypophysis) makes up the pituitary gland (hypophysis).

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Gastrointestinal tract

The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.

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Globe

A globe is a spherical model of Earth, of some other celestial body, or of the celestial sphere.

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Glutamine

Glutamine (symbol Gln or Q) is an α-amino acid that is used in the biosynthesis of proteins.

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Hypophyseal portal system

The hypophyseal portal system is a system of blood vessels in the microcirculation at the base of the brain, connecting the hypothalamus with the anterior pituitary.

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Hypothalamic–pituitary–prolactin axis

The hypothalamic–pituitary–prolactin axis (HPP axis), also known as the hypothalamic–pituitary–mammary axis or hypothalamic–pituitary–breast axis, is a hypothalamic–pituitary axis which includes the secretion of prolactin (PRL; luteotropin) from the lactotrophs of the pituitary gland into the circulation and the subsequent action of prolactin on tissues such as, particularly, the mammary glands or breasts.

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Hypothalamus

The hypothalamus(from Greek ὑπό, "under" and θάλαμος, thalamus) is a portion of the brain that contains a number of small nuclei with a variety of functions.

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Hypothyroidism

Hypothyroidism, also called underactive thyroid or low thyroid, is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormone.

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International nonproprietary name

The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.

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Intrathecal administration

Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF) and is useful in spinal anaesthesia, chemotherapy, or pain management applications.

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Median eminence

The median eminence, part of the inferior boundary of the hypothalamus in the brain, is attached to the infundibulum.

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Medication

A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.

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Nobel Prize in Physiology or Medicine

The Nobel Prize in Physiology or Medicine (Nobelpriset i fysiologi eller medicin), administered by the Nobel Foundation, is awarded once a year for outstanding discoveries in the fields of life sciences and medicine.

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Pancreatic islets

The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans.

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Paraventricular nucleus of hypothalamus

The paraventricular nucleus (PVN, PVA, or PVH) is a nucleus in the hypothalamus.

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Peptide hormone

Peptide hormones or protein hormones are hormones whose molecules are peptides or proteins, respectively.

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Prolactin

Prolactin (PRL), also known as luteotropic hormone or luteotropin, is a protein that is best known for its role in enabling mammals, usually females, to produce milk.

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Releasing and inhibiting hormones

Releasing hormones and inhibiting hormones are hormones whose main purpose is to control the release of other hormones, either by stimulating or inhibiting their release.

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Roger Guillemin

Roger Charles Louis Guillemin (born January 11, 1924 in Dijon, Bourgogne, France) received the National Medal of Science in 1976, and the Nobel prize for medicine in 1977 for his work on neurohormones, sharing the prize that year with Andrew Schally and Rosalyn Sussman Yalow.

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Spinocerebellar ataxia

Spinocerebellar ataxia (SCA), also known as spinocerebellar atrophy or spinocerebellar degeneration, is a progressive, degenerative, genetic disease with multiple types, each of which could be considered a disease in its own right.

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Structural formula

The structural formula of a chemical compound is a graphic representation of the molecular structure, showing how the atoms are arranged.

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Thyroid

The thyroid gland, or simply the thyroid, is an endocrine gland in the neck, consisting of two lobes connected by an isthmus.

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Thyroid-stimulating hormone

Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, TSH, or hTSH for human TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3) which stimulates the metabolism of almost every tissue in the body.

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Thyrotropic cell

Thyrotropes (also called thyrotrophs) are endocrine cells in the anterior pituitary which produce thyroid stimulating hormone (TSH) in response to thyrotropin releasing hormone (TRH).

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Thyrotropin-releasing hormone receptor

The thyrotropin-releasing hormone receptor (TRHR) is a G protein-coupled receptor which binds the tripeptide thyrotropin releasing hormone.

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TRH stimulation test

Prior to the availability of sensitive TSH assays, thyrotropin releasing hormone or TRH stimulation tests were relied upon for confirming and assessing the degree of suppression in suspected hyperthyroidism.

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Tropic hormone

Tropic hormones are hormones that have other endocrine glands as their target.

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Unified atomic mass unit

The unified atomic mass unit or dalton (symbol: u, or Da) is a standard unit of mass that quantifies mass on an atomic or molecular scale (atomic mass).

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Redirects here:

ATC code V04CJ02, ATCvet code QV04CJ02, Protirelin, Receptors, thyrotropin-releasing hormone, Relefact, Relefact trh, TRH, Thyroid releasing hormone, Thyroid stimulating hormone-releasing hormone, Thyroid-stimulating hormone releasing hormone, Thyrotropin releasing hormone, Thyrotropin-releasing factor.

References

[1] https://en.wikipedia.org/wiki/Thyrotropin-releasing_hormone

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