Faster access than browser!
67 relations: Abbott Laboratories, Abnormal posturing, Amnesia, Anticonvulsant, Antidepressant, Anxiety disorder, Aphasia, Approved Drug Products with Therapeutic Equivalence Evaluations, Benzodiazepine, Central nervous system, Cephalon, CI-966, Cmax (pharmacology), Color vision, Coma, Confusion, CYP3A, Cytochrome P450, Depression (mood), Deramciclane, Diarrhea, Dizziness, Drug overdose, Dystonia, Epilepsy, Epileptic seizure, Feces, Fibromyalgia, Food and Drug Administration, GABA reuptake inhibitor, GABA transporter 1, Gabapentin, Gamma-Aminobutyric acid, Hallucination, Headache, Hypertension, Hypotension, Hypoventilation, Kidney, Lethargy, Liver, Medication, Medicinal chemistry, Neuropathic pain, Neurotransmitter, Nipecotic acid, Novo Nordisk, Off-label use, Opioid, Panic disorder, ..., Paresthesia, Pharmacology, Placebo, Psychomotor agitation, Psychosis, Seizure threshold, Selective serotonin reuptake inhibitor, Serotonin–norepinephrine reuptake inhibitor, Side effect, SKF-89976A, Somnolence, Status epilepticus, Stuttering, Tablet (pharmacy), Tachycardia, Tremor, Weakness. Expand index (17 more) »
Abbott Laboratories
Abbott Laboratories is an American health care company with headquarters in Lake Bluff, Illinois, United States.
New!!: Tiagabine and Abbott Laboratories · See more »
Abnormal posturing
Abnormal posturing is an involuntary flexion or extension of the arms and legs, indicating severe brain injury.
New!!: Tiagabine and Abnormal posturing · See more »
Amnesia
Amnesia is a deficit in memory caused by brain damage, disease, or psychological trauma.
New!!: Tiagabine and Amnesia · See more »
Anticonvulsant
Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.
New!!: Tiagabine and Anticonvulsant · See more »
Antidepressant
Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.
New!!: Tiagabine and Antidepressant · See more »
Anxiety disorder
Anxiety disorders are a group of mental disorders characterized by significant feelings of anxiety and fear.
New!!: Tiagabine and Anxiety disorder · See more »
Aphasia
Aphasia is an inability to comprehend and formulate language because of damage to specific brain regions.
New!!: Tiagabine and Aphasia · See more »
Approved Drug Products with Therapeutic Equivalence Evaluations
The Drug Price and Competition Act (Hatch-Waxman Act) requires FDA to publish Approved Drug Products with Therapeutic Equivalence Evaluations, commonly known as the Orange Book.
New!!: Tiagabine and Approved Drug Products with Therapeutic Equivalence Evaluations · See more »
Benzodiazepine
Benzodiazepines (BZD, BZs), sometimes called "benzos", are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring.
New!!: Tiagabine and Benzodiazepine · See more »
Central nervous system
The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.
New!!: Tiagabine and Central nervous system · See more »
Cephalon
Cephalon, Inc. was a U.S. biopharmaceutical company co-founded in 1987 by Frank Baldino, Jr, pharmacologist, Michael Lewis, neuroscientist and James C. Kauer, organic chemist, all three former scientists with the DuPont Company.
New!!: Tiagabine and Cephalon · See more »
CI-966
CI-966 (developmental code name) is a central nervous system depressant acting as a GABA reuptake inhibitor, specifically a highly potent and selective blocker of the GABA transporter 1 (GAT-1) (IC50.
New!!: Tiagabine and CI-966 · See more »
Cmax (pharmacology)
Cmax is the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been administrated and before the administration of a second dose.
New!!: Tiagabine and Cmax (pharmacology) · See more »
Color vision
Color vision is the ability of an organism or machine to distinguish objects based on the wavelengths (or frequencies) of the light they reflect, emit, or transmit.
New!!: Tiagabine and Color vision · See more »
Coma
Coma is a state of unconsciousness in which a person cannot be awaken; fails to respond normally to painful stimuli, light, or sound; lacks a normal wake-sleep cycle; and does not initiate voluntary actions.
New!!: Tiagabine and Coma · See more »
Confusion
Confusion (from Latin confusĭo, -ōnis, from confundere: "to pour together;" "to mingle together;" "to confuse") is the state of being bewildered or unclear in one’s mind about something.
New!!: Tiagabine and Confusion · See more »
CYP3A
Cytochrome P450, family 3, subfamily A, also known as CYP3A, is a human gene.
New!!: Tiagabine and CYP3A · See more »
Cytochrome P450
Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.
New!!: Tiagabine and Cytochrome P450 · See more »
Depression (mood)
Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behavior, tendencies, feelings, and sense of well-being.
New!!: Tiagabine and Depression (mood) · See more »
Deramciclane
Deramciclane (EGIS-3886) is a non-benzodiazepine-type anxiolytic drug to treat various types of anxiety disorders.
New!!: Tiagabine and Deramciclane · See more »
Diarrhea
Diarrhea, also spelled diarrhoea, is the condition of having at least three loose or liquid bowel movements each day.
New!!: Tiagabine and Diarrhea · See more »
Dizziness
Dizziness is an impairment in spatial perception and stability.
New!!: Tiagabine and Dizziness · See more »
Drug overdose
The term drug overdose (or simply overdose or OD) describes the ingestion or application of a drug or other substance in quantities greater than are recommended or generally practiced.
New!!: Tiagabine and Drug overdose · See more »
Dystonia
Dystonia is a neurological movement disorder syndrome in which sustained or repetitive muscle contractions result in twisting and repetitive movements or abnormal fixed postures.
New!!: Tiagabine and Dystonia · See more »
Epilepsy
Epilepsy is a group of neurological disorders characterized by epileptic seizures.
New!!: Tiagabine and Epilepsy · See more »
Epileptic seizure
An epileptic seizure is a brief episode of signs or symptoms due to abnormally excessive or synchronous neuronal activity in the brain.
New!!: Tiagabine and Epileptic seizure · See more »
Feces
Feces (or faeces) are the solid or semisolid remains of the food that could not be digested in the small intestine.
New!!: Tiagabine and Feces · See more »
Fibromyalgia
Fibromyalgia (FM) is a medical condition characterised by chronic widespread pain and a heightened pain response to pressure.
New!!: Tiagabine and Fibromyalgia · See more »
Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
New!!: Tiagabine and Food and Drug Administration · See more »
GABA reuptake inhibitor
A GABA reuptake inhibitor (GRI) is a type of drug which acts as a reuptake inhibitor for the neurotransmitter gamma-Aminobutyric acid (GABA) by blocking the action of the gamma-Aminobutyric acid transporters (GATs).
New!!: Tiagabine and GABA reuptake inhibitor · See more »
GABA transporter 1
GABA transporter 1 (GAT1) also known as sodium- and chloride-dependent GABA transporter 1 is a protein that in humans is encoded by the SLC6A1 gene.
New!!: Tiagabine and GABA transporter 1 · See more »
Gabapentin
Gabapentin, sold under the brand name Neurontin among others, is a medication which is used to treat epilepsy (specifically partial seizures), neuropathic pain, hot flashes, and restless legs syndrome.
New!!: Tiagabine and Gabapentin · See more »
Gamma-Aminobutyric acid
gamma-Aminobutyric acid, or γ-aminobutyric acid, or GABA, is the chief inhibitory neurotransmitter in the mammalian central nervous system.
New!!: Tiagabine and Gamma-Aminobutyric acid · See more »
Hallucination
A hallucination is a perception in the absence of external stimulus that has qualities of real perception.
New!!: Tiagabine and Hallucination · See more »
Headache
Headache is the symptom of pain anywhere in the region of the head or neck.
New!!: Tiagabine and Headache · See more »
Hypertension
Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.
New!!: Tiagabine and Hypertension · See more »
Hypotension
Hypotension is low blood pressure, especially in the arteries of the systemic circulation.
New!!: Tiagabine and Hypotension · See more »
Hypoventilation
Hypoventilation (also known as respiratory depression) occurs when ventilation is inadequate (hypo meaning "below") to perform needed gas exchange.
New!!: Tiagabine and Hypoventilation · See more »
Kidney
The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.
New!!: Tiagabine and Kidney · See more »
Lethargy
Lethargy is a state of tiredness, weariness, fatigue, or lack of energy.
New!!: Tiagabine and Lethargy · See more »
Liver
The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.
New!!: Tiagabine and Liver · See more »
Medication
A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.
New!!: Tiagabine and Medication · See more »
Medicinal chemistry
Medicinal chemistry and pharmaceutical chemistry are disciplines at the intersection of chemistry, especially synthetic organic chemistry, and pharmacology and various other biological specialties, where they are involved with design, chemical synthesis and development for market of pharmaceutical agents, or bio-active molecules (drugs).
New!!: Tiagabine and Medicinal chemistry · See more »
Neuropathic pain
Neuropathic pain is pain caused by damage or disease affecting the somatosensory nervous system.
New!!: Tiagabine and Neuropathic pain · See more »
Neurotransmitter
Neurotransmitters are endogenous chemicals that enable neurotransmission.
New!!: Tiagabine and Neurotransmitter · See more »
Nipecotic acid
Nipecotic acid is a GABA uptake inhibitor used in scientific research.
New!!: Tiagabine and Nipecotic acid · See more »
Novo Nordisk
Novo Nordisk A/S is a Danish multinational pharmaceutical company headquartered in Bagsværd, Denmark, with production facilities in eight countries, and affiliates or offices in 75 countries.
New!!: Tiagabine and Novo Nordisk · See more »
Off-label use
Off-label use is the use of pharmaceutical drugs for an unapproved indication or in an unapproved age group, dosage, or route of administration.
New!!: Tiagabine and Off-label use · See more »
Opioid
Opioids are substances that act on opioid receptors to produce morphine-like effects.
New!!: Tiagabine and Opioid · See more »
Panic disorder
Panic disorder is an anxiety disorder characterized by reoccurring unexpected panic attacks.
New!!: Tiagabine and Panic disorder · See more »
Paresthesia
Paresthesia is an abnormal sensation such as tingling, tickling, pricking, numbness or burning of a person's skin with no apparent physical cause.
New!!: Tiagabine and Paresthesia · See more »
Pharmacology
Pharmacology is the branch of biology concerned with the study of drug action, where a drug can be broadly defined as any man-made, natural, or endogenous (from within body) molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism (sometimes the word pharmacon is used as a term to encompass these endogenous and exogenous bioactive species).
New!!: Tiagabine and Pharmacology · See more »
Placebo
A placebo is a substance or treatment of no intended therapeutic value.
New!!: Tiagabine and Placebo · See more »
Psychomotor agitation
Psychomotor agitation is a set of signs and symptoms that stem from mental tension and anxiety.
New!!: Tiagabine and Psychomotor agitation · See more »
Psychosis
Psychosis is an abnormal condition of the mind that results in difficulties telling what is real and what is not.
New!!: Tiagabine and Psychosis · See more »
Seizure threshold
The term seizure threshold is used to describe the balance between excitatory and inhibitory forces in the brain which affect how susceptible a person is to seizures.
New!!: Tiagabine and Seizure threshold · See more »
Selective serotonin reuptake inhibitor
Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders.
New!!: Tiagabine and Selective serotonin reuptake inhibitor · See more »
Serotonin–norepinephrine reuptake inhibitor
Serotonin–norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant drugs that treat major depressive disorder (MDD) and can also treat anxiety disorders, obsessive-compulsive disorder (OCD), attention-deficit hyperactivity disorder (ADHD), chronic neuropathic pain, fibromyalgia syndrome (FMS), and menopausal symptoms.
New!!: Tiagabine and Serotonin–norepinephrine reuptake inhibitor · See more »
Side effect
In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.
New!!: Tiagabine and Side effect · See more »
SKF-89976A
SKF-89976A is an anticonvulsant, acting as a GABA reuptake inhibitor via blockade of GAT-1.
New!!: Tiagabine and SKF-89976A · See more »
Somnolence
Somnolence (alternatively "sleepiness" or "drowsiness") is a state of strong desire for sleep, or sleeping for unusually long periods (compare hypersomnia).
New!!: Tiagabine and Somnolence · See more »
Status epilepticus
Status epilepticus (SE) is a single epileptic seizure lasting more than five minutes or two or more seizures within a five-minute period without the person returning to normal between them.
New!!: Tiagabine and Status epilepticus · See more »
Stuttering
Stuttering, also known as stammering, is a speech disorder in which the flow of speech is disrupted by involuntary repetitions and prolongations of sounds, syllables, words or phrases as well as involuntary silent pauses or blocks in which the person who stutters is unable to produce sounds. The term stuttering is most commonly associated with involuntary sound repetition, but it also encompasses the abnormal hesitation or pausing before speech, referred to by people who stutter as blocks, and the prolongation of certain sounds, usually vowels or semivowels. According to Watkins et al., stuttering is a disorder of "selection, initiation, and execution of motor sequences necessary for fluent speech production." For many people who stutter, repetition is the primary problem. The term "stuttering" covers a wide range of severity, encompassing barely perceptible impediments that are largely cosmetic to severe symptoms that effectively prevent oral communication. In the world, approximately four times as many men as women stutter, encompassing 70 million people worldwide, or about 1% of the world's population. The impact of stuttering on a person's functioning and emotional state can be severe. This may include fears of having to enunciate specific vowels or consonants, fears of being caught stuttering in social situations, self-imposed isolation, anxiety, stress, shame, being a possible target of bullying having to use word substitution and rearrange words in a sentence to hide stuttering, or a feeling of "loss of control" during speech. Stuttering is sometimes popularly seen as a symptom of anxiety, but there is actually no direct correlation in that direction (though as mentioned the inverse can be true, as social anxiety may actually develop in individuals as a result of their stuttering). Stuttering is generally not a problem with the physical production of speech sounds or putting thoughts into words. Acute nervousness and stress do not cause stuttering, but they can trigger stuttering in people who have the speech disorder, and living with a stigmatized disability can result in anxiety and high allostatic stress load (chronic nervousness and stress) that reduce the amount of acute stress necessary to trigger stuttering in any given person who stutters, exacerbating the problem in the manner of a positive feedback system; the name 'stuttered speech syndrome' has been proposed for this condition. Neither acute nor chronic stress, however, itself creates any predisposition to stuttering. The disorder is also variable, which means that in certain situations, such as talking on the telephone or in a large group, the stuttering might be more severe or less, depending on whether or not the stutterer is self-conscious about their stuttering. Stutterers often find that their stuttering fluctuates and that they have "good" days, "bad" days and "stutter-free" days. The times in which their stuttering fluctuates can be random. Although the exact etiology, or cause, of stuttering is unknown, both genetics and neurophysiology are thought to contribute. There are many treatments and speech therapy techniques available that may help decrease speech disfluency in some people who stutter to the point where an untrained ear cannot identify a problem; however, there is essentially no cure for the disorder at present. The severity of the person's stuttering would correspond to the amount of speech therapy needed to decrease disfluency. For severe stuttering, long-term therapy and hard work is required to decrease disfluency.
New!!: Tiagabine and Stuttering · See more »
Tablet (pharmacy)
A tablet is a pharmaceutical dosage form.
New!!: Tiagabine and Tablet (pharmacy) · See more »
Tachycardia
Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate.
New!!: Tiagabine and Tachycardia · See more »
Tremor
A tremor is an involuntary, somewhat rhythmic, muscle contraction and relaxation involving oscillations or twitching movements of one or more body parts.
New!!: Tiagabine and Tremor · See more »
Weakness
Weakness or asthenia is a symptom of a number of different conditions.
New!!: Tiagabine and Weakness · See more »
Redirects here:
ATC code N03AG06, ATCvet code QN03AG06, GABITRIL, Gabitril, Tiagabine hydrochloride.
References
[1] https://en.wikipedia.org/wiki/Tiagabine
