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Tight junction

Index Tight junction

Tight junctions, also known as occluding junctions or zonulae occludentes (singular, zonula occludens) are multiprotein junctional complex whose general function is to prevent leakage of transported solutes and water and seals the paracellular pathway. [1]

25 relations: Actin, Active transport, Bile, Blood–brain barrier, Cadherin, Cell junction, Cell membrane, Claudin, Collecting duct system, Cytoskeleton, Diffusion, Distal convoluted tubule, Endocytosis, Epithelium, Exocytosis, Gap junction, Kidney, Liver, Nephron, Occludin, Proximal tubule, Septate junctions, Solution, Tight junction protein, Zonulin.

Actin

Actin is a family of globular multi-functional proteins that form microfilaments.

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Active transport

Active transport is the movement of molecules across a membrane from a region of their lower concentration to a region of their higher concentration—in the direction against the concentration gradient.

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Bile

Bile or gall is a dark green to yellowish brown fluid, produced by the liver of most vertebrates, that aids the digestion of lipids in the small intestine.

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Blood–brain barrier

The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).

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Cadherin

Cadherins (named for "calcium-dependent adhesion") are a type of cell adhesion molecule (CAM) that is important in the formation of adherens junctions to bind cells with each other.

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Cell junction

A cell junction (or intercellular bridge) is a type of structure that exists within the tissue of some multicellular organisms, such as animals.

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).

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Claudin

Claudins are a family of proteins which, along with occludin, are the most important components of the tight junctions) (zonulae occludentes). Tight junctions establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm.

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Collecting duct system

The collecting duct system of the kidney consists of a series of tubules and ducts that physically connect nephrons to a minor calyx or directly to the renal pelvis.

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Cytoskeleton

A cytoskeleton is present in all cells of all domains of life (archaea, bacteria, eukaryotes).

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Diffusion

Diffusion is the net movement of molecules or atoms from a region of high concentration (or high chemical potential) to a region of low concentration (or low chemical potential) as a result of random motion of the molecules or atoms.

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Distal convoluted tubule

The distal convoluted tubule (DCT) is a portion of kidney nephron between the loop of Henle and the collecting tubule.

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Endocytosis

Endocytosis is a form of bulk transport in which a cell transports molecules (such as proteins) into the cell (endo- + cytosis) by engulfing them in an energy-using process.

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Epithelium

Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.

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Exocytosis

Exocytosis is a form of active transport in which a cell transports molecules (e.g., neurotransmitters and proteins) out of the cell (exo- + cytosis) by expelling them through an energy-dependent process.

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Gap junction

A gap junction may also be called a nexus or macula communicans.

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Kidney

The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.

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Liver

The liver, an organ only found in vertebrates, detoxifies various metabolites, synthesizes proteins, and produces biochemicals necessary for digestion.

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Nephron

The nephron (from Greek νεφρός – nephros, meaning "kidney") is the microscopic structural and functional unit of the kidney.

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Occludin

Occludin is a protein that in humans is encoded by the OCLN gene.

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Proximal tubule

The proximal tubule is the portion of the duct system of the nephron of the kidney which leads from Bowman's capsule to the loop of Henle.

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Septate junctions

Septate junctions are intercellular junctions found in invertebrate epithelial cells, and appear ladder-like under electron microscopy.

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Solution

In chemistry, a solution is a special type of homogeneous mixture composed of two or more substances.

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Tight junction protein

Tight junction protein are proteins that are involved in the formation and functioning of tight junctions; "Tight junction protein" may refer to.

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Zonulin

Zonulin (haptoglobin 2 precursor) is a protein that modulates the permeability of tight junctions between cells of the wall of the digestive tract.

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Redirects here:

Junctio occludens, Occluding junction, Occluding junctions, Tight junctions, Tight-junction, Zona occludens, Zonula Occludens, Zonula occludens, Zonula occludes, Zonulae occludente, Zonulae occludentes.

References

[1] https://en.wikipedia.org/wiki/Tight_junction

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