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Tissue factor

Index Tissue factor

Tissue factor, also called platelet tissue factor, factor III, or CD142 is a protein encoded by the F3 gene, present in subendothelial tissue and leukocytes. [1]

38 relations: Alternative splicing, Angiogenesis, Apoptosis, Atheroma, Cluster of differentiation, Coagulation, Cytokine, Cytokine receptor, Endothelium, Exon, Factor IX, Factor V, Factor VII, Factor VIII, Factor X, Fibroblast, Fibronectin, Gene, Gla domain, Glycoprotein, Hemostasis, Monocyte, Partial thromboplastin time, Phospholipid, Protein, Protein domain, Protein superfamily, Protein–protein interaction, Prothrombin time, Serine protease, Smooth muscle tissue, Thrombin, Thromboplastin, Transmembrane protein, Tumor necrosis factor alpha, Type II cytokine receptor, White blood cell, Zymogen.

Alternative splicing

Alternative splicing, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins.

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Angiogenesis

Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.

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Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Atheroma

An atheroma is a reversible accumulation of degenerative material in the inner layer of an artery wall.

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Cluster of differentiation

The cluster of differentiation (also known as cluster of designation or classification determinant and often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules providing targets for immunophenotyping of cells.

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Coagulation

Coagulation (also known as clotting) is the process by which blood changes from a liquid to a gel, forming a blood clot.

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Cytokine

Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.

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Cytokine receptor

Cytokine receptors are receptors that bind cytokines.

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Endothelium

Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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Exon

An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.

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Factor IX

Factor IX (or Christmas factor) is one of the serine proteases of the coagulation system; it belongs to peptidase family S1.

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Factor V

Factor V (pronounced factor five) is a protein of the coagulation system, rarely referred to as proaccelerin or labile factor.

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Factor VII

Factor VII (blood-coagulation factor VIIa, activated blood coagulation factor VII, formerly known as proconvertin) is one of the proteins that causes blood to clot in the coagulation cascade.

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Factor VIII

Factor VIII (FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor (AHF).

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Factor X

Factor X, also known by the eponym Stuart–Prower factor, is an enzyme of the coagulation cascade.

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Fibroblast

A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.

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Fibronectin

Fibronectin is a high-molecular weight (~440kDa) glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Gla domain

Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain is a protein domain that contains post-translational modifications of many glutamate residues by vitamin K-dependent carboxylation to form γ-carboxyglutamate (Gla).

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Glycoprotein

Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to amino acid side-chains.

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Hemostasis

Hemostasis or haemostasis is a process which causes bleeding to stop, meaning to keep blood within a damaged blood vessel (the opposite of hemostasis is hemorrhage).

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Monocyte

Monocytes are a type of leukocyte, or white blood cell.

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Partial thromboplastin time

The partial thromboplastin time (PTT) or activated partial thromboplastin time (aPTT or APTT) is a medical test that characterizes blood coagulation, also known as clotting.

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Phospholipid

Phospholipids are a class of lipids that are a major component of all cell membranes.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Protein domain

A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.

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Protein superfamily

A protein superfamily is the largest grouping (clade) of proteins for which common ancestry can be inferred (see homology).

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Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

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Prothrombin time

The prothrombin time (PT)—along with its derived measures of prothrombin ratio (PR) and international normalized ratio (INR)—are assays evaluating the extrinsic pathway of coagulation.

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Serine protease

Serine proteases (or serine endopeptidases) are enzymes that cleave peptide bonds in proteins, in which serine serves as the nucleophilic amino acid at the (enzyme's) active site.

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Smooth muscle tissue

Smooth muscle is an involuntary non-striated muscle.

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Thrombin

Thrombin (fibrinogenase, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, blood-coagulation factor IIa, factor IIa, E thrombin, beta-thrombin, gamma-thrombin) is a serine protease, an enzyme that, in humans, is encoded by the F2 gene.

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Thromboplastin

Thromboplastin (TPL) is a plasma protein aiding blood coagulation through catalyzing the conversion of prothrombin to thrombin.

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Transmembrane protein

A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the biological membrane to which it is permanently attached.

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Tumor necrosis factor alpha

Tumor necrosis factor (TNF, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction.

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Type II cytokine receptor

Type II cytokine receptors are transmembrane proteins that are expressed on the surface of certain cells, which bind and respond to a select group of cytokines.

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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Zymogen

A zymogen, also called a proenzyme, is an inactive precursor of an enzyme.

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Redirects here:

CD142, Cd142, Coagulation factor III, F3 (gene), Factor III.

References

[1] https://en.wikipedia.org/wiki/Tissue_factor

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