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Total synthesis

Index Total synthesis

Total synthesis is the complete chemical synthesis of a complex molecule, often a natural product, from simple, commercially available precursors. [1]

36 relations: Ammonium chloride, Angewandte Chemie, Camphor, Chemical synthesis, Chlorophyll, Cholesterol total synthesis, Colchicine, Corrin, Cortisone, Drug, Elias James Corey, Finland, Journal of the American Chemical Society, Lysergic acid, Molecule, Natural product, Nobel Prize, Nobel Prize in Chemistry, Oxytocin, Phil S. Baran, Process chemistry, Prostaglandin, Quinine total synthesis, Reagent, Reserpine, Retrosynthetic analysis, Robert Burns Woodward, Semisynthesis, Silver cyanate, Strychnine total synthesis, Urea, Vasopressin, Vincent du Vigneaud, Vitamin B12 total synthesis, Wöhler synthesis, William Henry Perkin.

Ammonium chloride

Ammonium chloride is an inorganic compound with the formula NH4Cl and a white crystalline salt that is highly soluble in water.

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Angewandte Chemie

Angewandte Chemie (meaning "Applied Chemistry") is a weekly peer-reviewed scientific journal that is published by Wiley-VCH on behalf of the German Chemical Society (Gesellschaft Deutscher Chemiker).

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Camphor

Camphor is a waxy, flammable, white or transparent solid with a strong aroma.

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Chemical synthesis

Chemical synthesis is a purposeful execution of chemical reactions to obtain a product, or several products.

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Chlorophyll

Chlorophyll (also chlorophyl) is any of several related green pigments found in cyanobacteria and the chloroplasts of algae and plants.

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Cholesterol total synthesis

Cholesterol total synthesis in chemistry describes the total synthesis of the complex biomolecule cholesterol and is considered a great scientific achievement.

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Colchicine

Colchicine is a medication most commonly used to treat gout.

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Corrin

Corrin is a heterocyclic compound.

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Cortisone

Cortisone, also known as 17α,21-dihydroxypregn-4-ene-3,11,20-trione, is a pregnane (21-carbon) steroid hormone.

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Drug

A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.

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Elias James Corey

Elias James "E.J." Corey (born July 12, 1928) is an American organic chemist.

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Finland

Finland (Suomi; Finland), officially the Republic of Finland is a country in Northern Europe bordering the Baltic Sea, Gulf of Bothnia, and Gulf of Finland, between Norway to the north, Sweden to the northwest, and Russia to the east.

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Journal of the American Chemical Society

The Journal of the American Chemical Society (also known as JACS) is a weekly peer-reviewed scientific journal that was established in 1879 by the American Chemical Society.

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Lysergic acid

Lysergic acid, also known as D-lysergic acid and (+)-lysergic acid, is a precursor for a wide range of ergoline alkaloids that are produced by the ergot fungus and found in the seeds of Turbina corymbosa (ololiuhqui), Argyreia nervosa (Hawaiian Baby Woodrose), and Ipomoea tricolor (morning glories, tlitliltzin).

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Molecule

A molecule is an electrically neutral group of two or more atoms held together by chemical bonds.

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Natural product

A natural product is a chemical compound or substance produced by a living organism—that is, found in nature.

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Nobel Prize

The Nobel Prize (Swedish definite form, singular: Nobelpriset; Nobelprisen) is a set of six annual international awards bestowed in several categories by Swedish and Norwegian institutions in recognition of academic, cultural, or scientific advances.

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Nobel Prize in Chemistry

The Nobel Prize in Chemistry (Nobelpriset i kemi) is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry.

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Oxytocin

Oxytocin (Oxt) is a peptide hormone and neuropeptide.

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Phil S. Baran

Phil S. Baran (born 1977) is a Professor in the Department of Chemistry at the Scripps Research Institute and Member of the Skaggs Institute for Chemical Biology.

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Process chemistry

Process chemistry is the arm of pharmaceutical chemistry concerned with the development and optimization of a synthetic scheme and pilot plant procedure to manufacture compounds for the drug development phase.

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Prostaglandin

The prostaglandins (PG) are a group of physiologically active lipid compounds having diverse hormone-like effects in animals.

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Quinine total synthesis

In total synthesis, the quinine total synthesis describes the efforts in synthesis of quinine over a 150-year period.

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Reagent

A reagent is a substance or compound added to a system to cause a chemical reaction, or added to test if a reaction occurs.

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Reserpine

Reserpine (also known by trade names Raudixin, Serpalan, Serpasil) is an indole alkaloid, Major Types Of Chemical Compounds In Plants & Animals Part II: Phenolic Compounds, Glycosides & Alkaloids. Wayne's Word: An On-Line Textbook of Natural History.

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Retrosynthetic analysis

Retrosynthetic analysis is a technique for solving problems in the planning of organic syntheses.

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Robert Burns Woodward

Robert Burns Woodward (April 10, 1917 – July 8, 1979) was an American organic chemist.

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Semisynthesis

Semisynthesis or partial chemical synthesis is a type of chemical synthesis that uses chemical compounds isolated from natural sources (e.g., microbial cell cultures or plant material) as the starting materials to produce other novel compounds with distinct chemical and medicinal properties.

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Silver cyanate

Silver cyanate is a chemical compound; it is the cyanate salt of silver.

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Strychnine total synthesis

Strychnine total synthesis in chemistry describes the total synthesis of the complex biomolecule strychnine.

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Urea

Urea, also known as carbamide, is an organic compound with chemical formula CO(NH2)2.

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Vasopressin

Vasopressin, also named antidiuretic hormone (ADH), arginine vasopressin (AVP) or argipressin, is a hormone synthesized as a peptide prohormone in neurons in the hypothalamus, and is converted to AVP.

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Vincent du Vigneaud

Vincent du Vigneaud (May 18, 1901 – December 11, 1978) was an American biochemist.

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Vitamin B12 total synthesis

The total synthesis of the complex biomolecule vitamin B12 was first accomplished by the collaborating research groups of Robert Burns Woodward at Harvard and Albert Eschenmoser at ETH in 1972.

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Wöhler synthesis

The Wöhler synthesis is the conversion of ammonium cyanate into urea.

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William Henry Perkin

Sir William Henry Perkin, FRS (12 March 1838 – 14 July 1907) was a British chemist and entrepreneur best known for his serendipitous discovery of the first synthetic organic dye, mauveine, made from aniline.

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Redirects here:

Formal synthesis, Total Synthesis, Total chemical synthesis, Total syntheses.

References

[1] https://en.wikipedia.org/wiki/Total_synthesis

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