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Toxin and Toxin-Target Database

Index Toxin and Toxin-Target Database

The Toxin and Toxin-Target Database (T3DB), also known as the Toxic Exposome Database, is a freely accessible online database of common substances that are toxic to humans, along with their protein, DNA or organ targets. [1]

26 relations: Biological target, Chemical structure, DNA, Drug, DrugBank, Exposome, Human Metabolome Database, KEGG, Lethal dose, List of biological databases, List of extremely hazardous substances, Mass spectrum, Mechanism of action, Metabolism, Metabolomics, Nuclear magnetic resonance spectroscopy, Pesticide, Poison, Pollutant, Protein, Relational database, Small Molecule Pathway Database, Toxicant, Toxicity, Toxin, Uremia.

Biological target

A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function.

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Chemical structure

A chemical structure determination includes a chemist's specifying the molecular geometry and, when feasible and necessary, the electronic structure of the target molecule or other solid.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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Drug

A drug is any substance (other than food that provides nutritional support) that, when inhaled, injected, smoked, consumed, absorbed via a patch on the skin, or dissolved under the tongue causes a temporary physiological (and often psychological) change in the body.

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DrugBank

The DrugBank database is a comprehensive, freely accessible, online database containing information on drugs and drug targets.

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Exposome

The exposome encompasses the totality of human environmental (i.e. non-genetic) exposures from conception onwards, complementing the genome, first proposed in 2005 by a cancer epidemiologist.

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Human Metabolome Database

The Human Metabolome Database (HMDB) is a comprehensive, high-quality, freely accessible, online database of small molecule metabolites found in the human body.

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KEGG

KEGG (Kyoto Encyclopedia of Genes and Genomes) is a collection of databases dealing with genomes, biological pathways, diseases, drugs, and chemical substances.

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Lethal dose

In toxicology, the lethal dose (LD) is an indication of the lethal toxicity of a given substance or type of radiation.

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List of biological databases

Biological databases are stores of biological information.

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List of extremely hazardous substances

This is the list of extremely hazardous substances defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002).

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Mass spectrum

A mass spectrum is an intensity vs.

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Mechanism of action

In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect.

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Metabolism

Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.

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Metabolomics

Metabolomics is the scientific study of chemical processes involving metabolites, the small molecule intermediates and products of metabolism.

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Nuclear magnetic resonance spectroscopy

Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a spectroscopic technique to observe local magnetic fields around atomic nuclei.

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Pesticide

Pesticides are substances that are meant to control pests, including weeds.

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Poison

In biology, poisons are substances that cause disturbances in organisms, usually by chemical reaction or other activity on the molecular scale, when an organism absorbs a sufficient quantity.

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Pollutant

A pollutant is a substance or energy introduced into the environment that has undesired effects, or adversely affects the usefulness of a resource.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Relational database

A relational database is a digital database based on the relational model of data, as proposed by E. F. Codd in 1970.

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Small Molecule Pathway Database

The Small Molecule Pathway Database (SMPDB) is a comprehensive, high-quality, freely accessible, online database containing more than 600 small molecule (i.e. metabolic) pathways found in humans.

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Toxicant

A toxicant (pronounced TOK-sih-kunt) is any toxic substance.

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Toxicity

Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism.

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Toxin

A toxin (from toxikon) is a poisonous substance produced within living cells or organisms; synthetic toxicants created by artificial processes are thus excluded.

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Uremia

Uremia is the condition of having "urea in the blood".

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Redirects here:

T3DB.

References

[1] https://en.wikipedia.org/wiki/Toxin_and_Toxin-Target_Database

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