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14 relations: Adjuvant, BRAF (gene), Cancer staging, Dabrafenib, Food and Drug Administration, Glutamic acid, MAP2K1, MAP2K2, MEK inhibitor, Melanoma, Phases of clinical research, Surgery, V600E, Valine.
Adjuvant
An adjuvant is a pharmacological or immunological agent that modifies the effect of other agents.
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BRAF (gene)
BRAF is a human gene that encodes a protein called B-Raf.
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Cancer staging
Cancer staging is the process of determining the extent to which a cancer has developed by growing and spreading.
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Dabrafenib
Dabrafenib (trade name Tafinlar, GSK2118436) is a drug for the treatment of cancers associated with a mutated version of the gene BRAF.
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Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
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Glutamic acid
Glutamic acid (symbol Glu or E) is an α-amino acid with formula.
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MAP2K1
Dual specificity mitogen-activated protein kinase kinase 1 is an enzyme that in humans is encoded by the MAP2K1 gene.
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MAP2K2
Dual specificity mitogen-activated protein kinase kinase 2 is an enzyme that in humans is encoded by the MAP2K2 gene.
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MEK inhibitor
A MEK inhibitor is a chemical or drug that inhibits the mitogen-activated protein kinase kinase enzymes MEK1 and/or MEK2.
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Melanoma
Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes.
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Phases of clinical research
The phases of clinical research are the steps in which scientists do experiments with a health intervention in an attempt to find enough evidence for a process which would be useful as a medical treatment.
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Surgery
Surgery (from the χειρουργική cheirourgikē (composed of χείρ, "hand", and ἔργον, "work"), via chirurgiae, meaning "hand work") is a medical specialty that uses operative manual and instrumental techniques on a patient to investigate or treat a pathological condition such as a disease or injury, to help improve bodily function or appearance or to repair unwanted ruptured areas.
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V600E
V600E is a mutation of the BRAF gene in which valine (V) is substituted by glutamic acid (E) at aminoacid 600.
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Valine
Valine (symbol Val or V) is an α-amino acid that is used in the biosynthesis of proteins.
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ATC code L01XE25, ATCvet code QL01XE25, C26H23FIN5O4, GSK1120212, Mekinist.
