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Transcription factories

Index Transcription factories

In genetics, transcription factories describe the discrete sites where transcription occurs in the nucleus. [1]

64 relations: Actin, Activator (genetics), Annual Review of Biochemistry, Biophysical Journal, Cell (biology), Cell nucleus, Cell type, Chromosomal translocation, Chromosome conformation capture, Coactivator (genetics), Confocal microscopy, Disease, DNA, DNA replication, Drosophila, Electron microscope, EMBO Reports, Embryo, Entropy, Fibroblast, Gene, Gene cluster, Genes & Development, Genetics, Genome, HeLa, Helicase, Immunofluorescence, In vitro, Journal of Cell Biology, Journal of Cell Science, Journal of Molecular Biology, Lamin, Locus (genetics), Molecular Biology of the Cell, Mouse, Nature Genetics, Nature Methods, Nuclear matrix, Nuclear structure, Nucleic Acids Research, Nucleolus, Nucleoprotein, Point mutation, Polytene chromosome, Porosity, Proceedings of the National Academy of Sciences of the United States of America, Protein, Regulation of gene expression, Repressor, ..., Restriction enzyme, RNA polymerase, RNA polymerase I, RNA polymerase II, RNA polymerase III, RNA splicing, Species, Spectrin, The EMBO Journal, Tissue (biology), Transcription (biology), Transcription (journal), Transcription factor, Western blot. Expand index (14 more) »

Actin

Actin is a family of globular multi-functional proteins that form microfilaments.

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Activator (genetics)

A transcriptional activator is a protein (transcription factor) that increases gene transcription of a gene or set of genes.

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Annual Review of Biochemistry

Annual Review of Biochemistry is an annual peer reviewed scientific journal published by Annual Reviews, a nonprofit scientific publisher.

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Biophysical Journal

The Biophysical Journal is a peer-reviewed scientific journal published by Cell Press on behalf of the Biophysical Society.

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Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

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Cell nucleus

In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.

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Cell type

A cell type is a classification used to distinguish between morphologically or phenotypically distinct cell forms within a species.

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Chromosomal translocation

In genetics, a chromosome translocation is a chromosome abnormality caused by rearrangement of parts between nonhomologous chromosomes.

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Chromosome conformation capture

Chromosome conformation capture techniques (often abbreviated to 3C technologies or 3C-based methods) are a set of molecular biology methods used to analyze the spatial organization of chromatin in a cell.

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Coactivator (genetics)

A coactivator is a type of transcriptional coregulator that binds to an activator (a transcription factor) to increase the rate of transcription of a gene or set of genes.

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Confocal microscopy

Confocal microscopy, most frequently confocal laser scanning microscopy (CLSM) or laser confocal scanning microscopy (LCSM), is an optical imaging technique for increasing optical resolution and contrast of a micrograph by means of using a spatial pinhole to block out-of-focus light in image formation.

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Disease

A disease is any condition which results in the disorder of a structure or function in an organism that is not due to any external injury.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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DNA replication

In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.

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Drosophila

Drosophila is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit.

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Electron microscope

An electron microscope is a microscope that uses a beam of accelerated electrons as a source of illumination.

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EMBO Reports

EMBO Reports is a peer-reviewed scientific journal covering research related to biology at a molecular level.

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Embryo

An embryo is an early stage of development of a multicellular diploid eukaryotic organism.

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Entropy

In statistical mechanics, entropy is an extensive property of a thermodynamic system.

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Fibroblast

A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Gene cluster

A gene family is a set of homologous genes within one organism.

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Genes & Development

Genes & Development is a peer-reviewed scientific journal covering molecular biology, molecular genetics, cell biology, and development.

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Genetics

Genetics is the study of genes, genetic variation, and heredity in living organisms.

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Genome

In the fields of molecular biology and genetics, a genome is the genetic material of an organism.

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HeLa

HeLa (also Hela or hela) is a cell type in an immortal cell line used in scientific research.

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Helicase

Helicases are a class of enzymes vital to all living organisms.

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Immunofluorescence

Immunofluorescence is a technique used for light microscopy with a fluorescence microscope and is used primarily on microbiological samples.

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In vitro

In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.

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Journal of Cell Biology

Journal of Cell Biology is an international, peer-reviewed journal owned by The Rockefeller University and published by Rockefeller University Press.

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Journal of Cell Science

The Journal of Cell Science (formerly the Quarterly Journal of Microscopical Science) is a peer-reviewed scientific journal in the field of cell biology.

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Journal of Molecular Biology

The Journal of Molecular Biology is a peer-reviewed scientific journal published weekly by Elsevier.

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Lamin

Nuclear lamins, also known as Class V intermediate filaments, are fibrous proteins providing structural function and transcriptional regulation in the cell nucleus.

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Locus (genetics)

A locus (plural loci) in genetics is a fixed position on a chromosome, like the position of a gene or a marker (genetic marker).

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Molecular Biology of the Cell

Molecular Biology of the Cell is a biweekly peer-reviewed scientific journal published by the American Society for Cell Biology.

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Mouse

A mouse (Mus), plural mice, is a small rodent characteristically having a pointed snout, small rounded ears, a body-length scaly tail and a high breeding rate.

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Nature Genetics

Nature Genetics is a scientific journal founded as part of the ''Nature'' family of journals in 1992.

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Nature Methods

Nature Methods is a monthly peer-reviewed scientific journal covering new scientific techniques.

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Nuclear matrix

In biology, the nuclear matrix is the network of fibres found throughout the inside of a cell nucleus and is somewhat analogous to the cell cytoskeleton.

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Nuclear structure

Understanding the structure of the atomic nucleus is one of the central challenges in nuclear physics.

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Nucleic Acids Research

Nucleic Acids Research is an open-access peer-reviewed scientific journal published by Oxford University Press.

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Nucleolus

The nucleolus (plural nucleoli) is the largest structure in the nucleus of eukaryotic cells.

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Nucleoprotein

Nucleoproteins are any proteins that are structurally associated with nucleic acids, either DNA or RNA.

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Point mutation

A point mutation is a genetic mutation where a single nucleotide base is changed, inserted or deleted from a sequence of DNA or RNA.

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Polytene chromosome

Polytene chromosomes are large chromosomes which have thousands of DNA strands.

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Porosity

Porosity or void fraction is a measure of the void (i.e. "empty") spaces in a material, and is a fraction of the volume of voids over the total volume, between 0 and 1, or as a percentage between 0% and 100%.

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Proceedings of the National Academy of Sciences of the United States of America

Proceedings of the National Academy of Sciences of the United States of America (PNAS) is the official scientific journal of the National Academy of Sciences, published since 1915.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Regulation of gene expression

Regulation of gene expression includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA), and is informally termed gene regulation.

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Repressor

In molecular genetics, a repressor is a DNA- or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated silencers.

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Restriction enzyme

A restriction enzyme or restriction endonuclease is an enzyme that cleaves DNA into fragments at or near specific recognition sites within the molecule known as restriction sites.

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RNA polymerase

RNA polymerase (ribonucleic acid polymerase), both abbreviated RNAP or RNApol, official name DNA-directed RNA polymerase, is a member of a family of enzymes that are essential to life: they are found in all organisms (-species) and many viruses.

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RNA polymerase I

RNA polymerase 1 (also known as Pol I) is, in higher eukaryotes, the polymerase that only transcribes ribosomal RNA (but not 5S rRNA, which is synthesized by RNA polymerase III), a type of RNA that accounts for over 50% of the total RNA synthesized in a cell.

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RNA polymerase II

RNA polymerase II (RNAP II and Pol II) is a multiprotein complex.

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RNA polymerase III

In eukaryote cells, RNA polymerase III (also called Pol III) transcribes DNA to synthesize ribosomal 5S rRNA, tRNA and other small RNAs.

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RNA splicing

In molecular biology, splicing is the editing of the nascent precursor messenger RNA (pre-mRNA) transcript into a mature messenger RNA (mRNA).

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Species

In biology, a species is the basic unit of classification and a taxonomic rank, as well as a unit of biodiversity, but it has proven difficult to find a satisfactory definition.

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Spectrin

Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane in eukaryotic cells.

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The EMBO Journal

The EMBO Journal is a peer-reviewed scientific journal focusing on full-length papers describing original research of general interest in molecular biology and related areas.

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Tissue (biology)

In biology, tissue is a cellular organizational level between cells and a complete organ.

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Transcription (biology)

Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.

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Transcription (journal)

Transcription is a scientific journal published by Taylor & Francis focusing on the subject of the transcription of DNA.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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Western blot

The western blot (sometimes called the protein immunoblot) is a widely used analytical technique used in molecular biology, immunogenetics and other molecular biology disciplines to detect specific proteins in a sample of tissue homogenate or extract.

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References

[1] https://en.wikipedia.org/wiki/Transcription_factories

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