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Translocon

Index Translocon

The translocon (commonly known as a translocator or translocation channel) is a complex of proteins associated with the translocation of polypeptides across membranes. [1]

25 relations: Archaea, Atomic force microscopy, Bacteria, Brownian ratchet, Cytosol, Endoplasmic reticulum, Endoplasmic-reticulum-associated protein degradation, Eukaryote, Hydrophobe, Lipid bilayer, Membrane protein, Oligosaccharyltransferase, Pathogen, Peptide, Prokaryote, Proteasome, Protein, Ribosome, Sec61, SecY protein, Signal peptidase, Signal recognition particle, Translation (biology), Transmembrane domain, Virulence factor.

Archaea

Archaea (or or) constitute a domain of single-celled microorganisms.

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Atomic force microscopy

Atomic force microscopy (AFM) or scanning force microscopy (SFM) is a very-high-resolution type of scanning probe microscopy (SPM), with demonstrated resolution on the order of fractions of a nanometer, more than 1000 times better than the optical diffraction limit.

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Bacteria

Bacteria (common noun bacteria, singular bacterium) is a type of biological cell.

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Brownian ratchet

In the philosophy of thermal and statistical physics, the Brownian ratchet or Feynman-Smoluchowski ratchet is a thought experiment about an apparent perpetual motion machine first analysed in 1912 by Polish physicist Marian SmoluchowskiM.

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Cytosol

The cytosol, also known as intracellular fluid (ICF) or cytoplasmic matrix, is the liquid found inside cells.

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Endoplasmic reticulum

The endoplasmic reticulum (ER) is a type of organelle found in eukaryotic cells that forms an interconnected network of flattened, membrane-enclosed sacs or tube-like structures known as cisternae.

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Endoplasmic-reticulum-associated protein degradation

Endoplasmic-reticulum-associated protein degradation (ERAD) designates a cellular pathway which targets misfolded proteins of the endoplasmic reticulum for ubiquitination and subsequent degradation by a protein-degrading complex, called the proteasome.

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Eukaryote

Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).

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Hydrophobe

In chemistry, hydrophobicity is the physical property of a molecule (known as a hydrophobe) that is seemingly repelled from a mass of water.

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Lipid bilayer

The lipid bilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid molecules.

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Membrane protein

Membrane proteins are proteins that interact with, or are part of, biological membranes.

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Oligosaccharyltransferase

Oligosaccharyltransferase or OST is a membrane protein complex that transfers a 14-sugar oligosaccharide from dolichol to nascent protein.

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Pathogen

In biology, a pathogen (πάθος pathos "suffering, passion" and -γενής -genēs "producer of") or a '''germ''' in the oldest and broadest sense is anything that can produce disease; the term came into use in the 1880s.

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Peptide

Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.

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Prokaryote

A prokaryote is a unicellular organism that lacks a membrane-bound nucleus, mitochondria, or any other membrane-bound organelle.

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Proteasome

Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds.

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Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Ribosome

The ribosome is a complex molecular machine, found within all living cells, that serves as the site of biological protein synthesis (translation).

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Sec61

Sec61 is an endoplasmic reticulum (ER) membrane protein translocator (aka translocon).

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SecY protein

The SecY protein is the main transmembrane subunit of the eubacterial Sec or Type II secretory pathway and a protein-secreting ATPase complex, also known as a translocon.

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Signal peptidase

Signal peptidases are enzymes that convert secretory and some membrane proteins to their mature forms by cleaving their signal peptides from their N-terminals.

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Signal recognition particle

The signal recognition particle (SRP) is an abundant, cytosolic, universally conserved ribonucleoprotein (protein-RNA complex) that recognizes and targets specific proteins to the endoplasmic reticulum in eukaryotes and the plasma membrane in prokaryotes.

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Translation (biology)

In molecular biology and genetics, translation is the process in which ribosomes in the cytoplasm or ER synthesize proteins after the process of transcription of DNA to RNA in the cell's nucleus.

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Transmembrane domain

Transmembrane domain usually denotes a transmembrane segment of single alpha helix of a transmembrane protein.

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Virulence factor

Virulence factors are molecules produced by bacteria, viruses, fungi, and protozoa that add to their effectiveness and enable them to achieve the following.

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Redirects here:

Sec proteins, Translocator pore.

References

[1] https://en.wikipedia.org/wiki/Translocon

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