104 relations: Abdominal pain, Active metabolite, Agonist, Aldosterone, Androgen, Androgen receptor, Antiandrogen, Antiestrogen, Antiglucocorticoid, Antigonadotropin, Antimineralocorticoid, Anxiety, Argentina, Atrophic vaginitis, Austria, Belgium, Binding selectivity, Bioavailability, Biological half-life, Biological target, Bloating, Brazil, Breast pain, Canada, Chile, Cmax (pharmacology), Combined oral contraceptive pill, Conjugated estrogens, Cramp, Decidualization, Demegestone, Denmark, Depression (mood), Derivative (chemistry), Dexamethasone, Endometriosis, Endometrium, Estradiol (medication), Estrogen (medication), Estrogen receptor, Ethinylestradiol, Europe, Finland, France, GABAA receptor, Gestodene, Glucocorticoid, Glucocorticoid receptor, Headache, Hormone, ..., Hot flash, Human serum albumin, Hydroxy group, Hydroxylation, Italy, Latin America, Ligand (biochemistry), Lithuania, Menopause, Metabolism, Metabolite, Metrorrhagia, Mexico, Mineralocorticoid, Mineralocorticoid receptor, Nandrolone, Nausea, Neurosteroid, Norway, Oral administration, Organic compound, Osteoporosis, Ovulation, Pharmacodynamics, Pharmacokinetics, Plasma protein binding, Postmenopausal hormone therapy, Potency (pharmacology), Pregnancy, Progesterone, Progesterone (medication), Progesterone receptor, Progestin, Progestogen, Promegestone, Sanofi, Sedative, Side effect, Steroid, Steroid hormone receptor, Sweden, Symptom, Testosterone (medication), Tissue (biology), Trademark distinctiveness, Transdermal patch, United States, Vaginal bleeding, Venezuela, Wyeth, 17α-Methyl-19-norprogesterone, 17α-Methylprogesterone, 19-Norpregnane, 19-Norprogesterone. Expand index (54 more) » « Shrink index
Abdominal pain, also known as a stomach ache, is a symptom associated with both non-serious and serious medical issues.
An active metabolite is an active form of a drug after it has been processed by the body.
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
Aldosterone, the main mineralocorticoid hormone, is a steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland.
An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone in the cytoplasm and then translocating into the nucleus.
Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body.
Antiestrogens, also known as estrogen antagonists or estrogen blockers, are a class of drugs which prevent estrogens like estradiol from mediating their biological effects in the body.
An antiglucocorticoid is a drug which reduces glucocorticoid activity in the body.
An antigonadotropin is a drug which suppresses the activity and/or downstream effects of one or both of the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
An antimineralocorticoid, MCRA, or an aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors.
Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behaviour such as pacing back and forth, somatic complaints, and rumination.
Argentina, officially the Argentine Republic (República Argentina), is a federal republic located mostly in the southern half of South America.
Atrophic vaginitis is the chronic and progressive inflammation of the vagina (and the lower urinary tract) due to the thinning and shrinking of the vaginal tissues and is often accompanied by vulvar and urinary pathologies.
Austria (Österreich), officially the Republic of Austria (Republik Österreich), is a federal republic and a landlocked country of over 8.8 million people in Central Europe.
Belgium, officially the Kingdom of Belgium, is a country in Western Europe bordered by France, the Netherlands, Germany and Luxembourg.
Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.
In pharmacology, bioavailability (BA or F) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.
The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.
A biological target is anything within a living organism to which some other entity (like an endogenous ligand or a drug) is directed and/or binds, resulting in a change in its behavior or function.
Abdominal bloating is a symptom that can appear at any age, generally associated with functional gastrointestinal disorders or organic diseases, but can also appear alone.
Brazil (Brasil), officially the Federative Republic of Brazil (República Federativa do Brasil), is the largest country in both South America and Latin America.
Breast pain is a medical symptom that is most often associated with a developing disease or condition of the breast.
Canada is a country located in the northern part of North America.
Chile, officially the Republic of Chile, is a South American country occupying a long, narrow strip of land between the Andes to the east and the Pacific Ocean to the west.
Christmas is an annual festival commemorating the birth of Jesus Christ,Martindale, Cyril Charles.
The Christmas season, also called the festive season, or the holiday season (mainly in the U.S. and Canada; often simply called the holidays),, is an annually recurring period recognized in many Western and Western-influenced countries that is generally considered to run from late November to early January.
Christmas Eve is the evening or entire day before Christmas Day, the festival commemorating the birth of Jesus.
Christmas traditions vary from country to country.
Cmax is the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been administrated and before the administration of a second dose.
The combined oral contraceptive pill (COCP), often referred to as the birth control pill or colloquially as "the pill", is a type of birth control that is designed to be taken orally by women.
Conjugated estrogens (CEs), or conjugated equine estrogens (CEEs), sold under the brand name Premarin (a contraction of "pregnant mares' urine") among others, is an estrogen medication which is used in menopausal hormone therapy and for various other indications.
A cramp is a sudden, involuntary muscle contraction or over-shortening; while generally temporary and non-damaging, they can cause significant pain, and a paralysis-like immobility of the affected muscle.
Decidualization is a process that results in significant changes to cells of the endometrium in preparation for, and during, pregnancy.
Demegestone, sold under the brand name Lutionex, is a progestin medication which was previously used to treat luteal insufficiency but is now no longer marketed.
Denmark (Danmark), officially the Kingdom of Denmark,Kongeriget Danmark,.
Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behavior, tendencies, feelings, and sense of well-being.
In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.
Dexamethasone is a type of corticosteroid medication.
Endometriosis is a condition in which the endometrium, the layer of tissue that normally covers the inside of the uterus, grows outside of it.
The endometrium is the inner epithelial layer, along with its mucous membrane, of the mammalian uterus.
Estradiol, also spelled oestradiol, is a medication and naturally occurring steroid hormone.
An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
Estrogen receptors (ERs) are a group of proteins found inside cells.
Ethinylestradiol (EE) is an estrogen medication which is used widely in birth control pills in combination with progestins.
Europe is a continent located entirely in the Northern Hemisphere and mostly in the Eastern Hemisphere.
Finland (Suomi; Finland), officially the Republic of Finland is a country in Northern Europe bordering the Baltic Sea, Gulf of Bothnia, and Gulf of Finland, between Norway to the north, Sweden to the northwest, and Russia to the east.
France, officially the French Republic (République française), is a sovereign state whose territory consists of metropolitan France in Western Europe, as well as several overseas regions and territories.
The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.
Gestodene, sold under the brand names Femodene and Minulet among others, is a progestin medication which is used in birth control pills for women.
Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones.
The glucocorticoid receptor (GR, or GCR) also known as NR3C1 (nuclear receptor subfamily 3, group C, member 1) is the receptor to which cortisol and other glucocorticoids bind.
Headache is the symptom of pain anywhere in the region of the head or neck.
A hormone (from the Greek participle “ὁρμῶ”, "to set in motion, urge on") is any member of a class of signaling molecules produced by glands in multicellular organisms that are transported by the circulatory system to target distant organs to regulate physiology and behaviour.
Hot flashes (American English) or hot flushes (British English) are a form of flushing due to reduced levels of estradiol.
Human serum albumin is the serum albumin found in human blood.
A hydroxy or hydroxyl group is the entity with the formula OH.
Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound.
Italy (Italia), officially the Italian Republic (Repubblica Italiana), is a sovereign state in Europe.
Latin America is a group of countries and dependencies in the Western Hemisphere where Spanish, French and Portuguese are spoken; it is broader than the terms Ibero-America or Hispanic America.
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
Lithuania (Lietuva), officially the Republic of Lithuania (Lietuvos Respublika), is a country in the Baltic region of northern-eastern Europe.
Menopause, also known as the climacteric, is the time in most women's lives when menstrual periods stop permanently, and they are no longer able to bear children.
Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.
A metabolite is the intermediate end product of metabolism.
Mexico (México; Mēxihco), officially called the United Mexican States (Estados Unidos Mexicanos) is a federal republic in the southern portion of North America.
Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones.
The mineralocorticoid receptor (or MR, MLR, MCR), also known as the aldosterone receptor or nuclear receptor subfamily 3, group C, member 2, (NR3C2) is a protein that in humans is encoded by the NR3C2 gene that is located on chromosome 4q31.1-31.2.
Nandrolone, also known as 19-nortestosterone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as nandrolone decanoate (brand name Deca-Durabolin) and nandrolone phenylpropionate (brand name Durabolin).
Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.
Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors.
New Year is the time or day at which a new calendar year begins and the calendar's year count increments by one.
New Year's Day, also called simply New Year's or New Year, is observed on January 1, the first day of the year on the modern Gregorian calendar as well as the Julian calendar.
In the Gregorian calendar, New Year's Eve (also known as Old Year's Day or Saint Sylvester's Day in many countries), the last day of the year, is on 31 December which is the seventh day of Christmastide.
Norway (Norwegian: (Bokmål) or (Nynorsk); Norga), officially the Kingdom of Norway, is a unitary sovereign state whose territory comprises the western portion of the Scandinavian Peninsula plus the remote island of Jan Mayen and the archipelago of Svalbard.
In chemistry, an organic compound is generally any chemical compound that contains carbon.
Osteoporosis is a disease where increased bone weakness increases the risk of a broken bone.
Ovulation is the release of eggs from the ovaries.
Pharmacodynamics is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).
Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to determining the fate of substances administered to a living organism.
Plasma protein binding refers to the degree to which medications attach to proteins within the blood.
Menopausal hormone therapy (MHT), or postmenopausal hormone therapy (PHT, PMHT), also known as hormone replacement therapy in menopause, is a form of hormone replacement therapy (HRT) which is used in postmenopausal, perimenopausal, and surgically menopausal women.
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis of humans and other species.
Progesterone is a medication and naturally occurring steroid hormone.
The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.
A progestin is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.
Progestogens, also sometimes spelled progestagens or gestagens, are a class of steroid hormones that bind to and activate the progesterone receptor (PR).
Promegestone, sold under the brand name Surgestone, is a progestin medication which is used in menopausal hormone therapy and in the treatment of gynecological disorders.
Sanofi S.A. is a French multinational pharmaceutical company headquartered in Gentilly, France, as of 2013 the world's fifth-largest by prescription sales.
A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement.
In medicine, a side effect is an effect, whether therapeutic or adverse, that is secondary to the one intended; although the term is predominantly employed to describe adverse effects, it can also apply to beneficial, but unintended, consequences of the use of a drug.
A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.
Steroid hormone receptors are found in the nucleus, cytosol, and also on the plasma membrane of target cells.
Sweden (Sverige), officially the Kingdom of Sweden (Swedish), is a Scandinavian country in Northern Europe.
A symptom (from Greek σύμπτωμα, "accident, misfortune, that which befalls", from συμπίπτω, "I befall", from συν- "together, with" and πίπτω, "I fall") is a departure from normal function or feeling which is noticed by a patient, reflecting the presence of an unusual state, or of a disease.
Testosterone is a medication and naturally occurring steroid hormone.
In biology, tissue is a cellular organizational level between cells and a complete organ.
Trademark distinctiveness is an important concept in the law governing trademarks and service marks.
A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream.
The United States of America (USA), commonly known as the United States (U.S.) or America, is a federal republic composed of 50 states, a federal district, five major self-governing territories, and various possessions.
Vaginal bleeding is any bleeding through the vagina, including bleeding from the vaginal wall itself, as well as (and more commonly) bleeding from another location of the female reproductive system, often the uterus.
Venezuela, officially denominated Bolivarian Republic of Venezuela (República Bolivariana de Venezuela),Previously, the official name was Estado de Venezuela (1830–1856), República de Venezuela (1856–1864), Estados Unidos de Venezuela (1864–1953), and again República de Venezuela (1953–1999).
Wyeth was a pharmaceutical company purchased by Pfizer in 2009.
17α-Methyl-19-norprogesterone (developmental code name H-3510), also known as 17α-methyl-19-norpregn-4-ene-3,20-dione, is a progestin which was never marketed.
17α-Methylprogesterone (17α-MP), or 17α-methylpregn-4-ene-3,20-dione, is a steroidal progestin related to progesterone that was synthesized and characterized in 1949 but was never marketed.
19-Norpregnane, also known as 13β-methyl-17β-ethylgonane, is a norsteroid and the 19-demethyl analogue of pregnane.
19-Norprogesterone, also known as 19-norpregn-4-ene-3,20-dione, is a steroidal progestin and close analogue of the sex hormone progesterone, lacking only the C19 methyl group of that molecule.
2018 has been designated as the third International Year of the Reef by the International Coral Reef Initiative.
2019 (MMXIX) will be a common year starting on Tuesday of the Gregorian calendar, the 2019th year of the Common Era (CE) and Anno Domini (AD) designations, the 19th year of the 3rd millennium, the 19th year of the 21st century, and the 10th and last year of the 2010s decade.
21(S)-Hydroxypromegestone, 21(S)-hydroxypromegestone, 21-Hydroxypromegestone, 21-hydroxypromegestone, 21S-Hydroxypromegestone, 21S-hydroxypromegestone, 21β-Hydroxypromegestone, 21β-hydroxypromegestone, Ginotex, Lovelle, Lovelle Ciclico, Lovelle Continuo, Lovelle ciclico, Lovelle continuo, Minique, Ondeva, PSK 3987, PSK-3987, PSK3987, R 27,987, R 27987, R-27,987, R-27987, R27987, RU 27,987, RU 27987, RU-27,987, RU-27987, RU27987, Totelle, Totelle Ciclico, Totelle Ciclo, Totelle Continuo, Totelle Continuous, Totelle Cycle, Totelle Cyclic, Totelle Cyclical, Totelle Cyclo, Totelle Secuencial, Totelle Sekvens, Totelle Sequential, Totelle ciclico, Totelle ciclo, Totelle continuo, Totelle continuous, Totelle cycle, Totelle cyclic, Totelle cyclical, Totelle cyclo, Totelle secuencial, Totelle sekvens, Totelle sequential.