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Trimetaphan camsilate

Index Trimetaphan camsilate

Trimetaphan camsilate (INN) or trimethaphan camsylate (USAN), trade name Arfonad, is a drug that counteracts cholinergic transmission at the ganglion type of nicotinic receptors of the autonomic ganglia and therefore blocks both the sympathetic nervous system and the parasympathetic nervous system. [1]

35 relations: Accommodation (eye), Acetylcholine, Aortic dissection, Autonomic ganglion, Blood pressure, Blood vessel, Blood–brain barrier, Cell membrane, Central nervous system, Cholinergic, Ciliary muscle, Circulatory system, Constipation, Cycloplegia, Gastrointestinal tract, Heart, Human eye, Hypertensive crisis, International nonproprietary name, Intramuscular injection, Intravenous therapy, Kidney, Lens (anatomy), Lipid, Neurosurgery, Nicotinic acetylcholine receptor, Orthostatic hypotension, Parasympathetic nervous system, Pulmonary edema, Receptor antagonist, Sulfonium, Sympathetic nervous system, Tachycardia, United States Adopted Name, Vasodilation.

Accommodation (eye)

Accommodation is the process by which the vertebrate eye changes optical power to maintain a clear image or focus on an object as its distance varies.

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Acetylcholine

Acetylcholine (ACh) is an organic chemical that functions in the brain and body of many types of animals, including humans, as a neurotransmitter—a chemical message released by nerve cells to send signals to other cells.

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Aortic dissection

Aortic dissection (AD) occurs when an injury to the innermost layer of the aorta allows blood to flow between the layers of the aortic wall, forcing the layers apart.

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Autonomic ganglion

An autonomic ganglion is a cluster of nerve cell bodies (a ganglion) in the autonomic nervous system.

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Blood pressure

Blood pressure (BP) is the pressure of circulating blood on the walls of blood vessels.

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Blood vessel

The blood vessels are the part of the circulatory system, and microcirculation, that transports blood throughout the human body.

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Blood–brain barrier

The blood–brain barrier (BBB) is a highly selective semipermeable membrane barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS).

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).

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Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Cholinergic

In general, the word choline refers to the various quaternary ammonium salts containing the ''N'',''N'',''N''-trimethylethanolammonium cation.

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Ciliary muscle

The ciliary muscle is a ring of smooth muscleSchachar, Ronald A. (2012). "Anatomy and Physiology." (Chapter 4). in the eye's middle layer (vascular layer) that controls accommodation for viewing objects at varying distances and regulates the flow of aqueous humour into Schlemm's canal. It changes the shape of the lens within the eye, not the size of the pupil which is carried out by the sphincter pupillae muscle and dilator pupillae.

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Circulatory system

The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.

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Constipation

Constipation refers to bowel movements that are infrequent or hard to pass.

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Cycloplegia

Cycloplegia is paralysis of the ciliary muscle of the eye, resulting in a loss of accommodation.

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Gastrointestinal tract

The gastrointestinal tract (digestive tract, digestional tract, GI tract, GIT, gut, or alimentary canal) is an organ system within humans and other animals which takes in food, digests it to extract and absorb energy and nutrients, and expels the remaining waste as feces.

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Heart

The heart is a muscular organ in most animals, which pumps blood through the blood vessels of the circulatory system.

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Human eye

The human eye is an organ which reacts to light and pressure.

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Hypertensive crisis

Severely elevated blood pressure (equal to or greater than a systolic 180 or diastolic of 110—sometimes termed malignant or accelerated hypertension) is referred to as a hypertensive crisis, as blood pressure at this level confers a high risk of complications.

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International nonproprietary name

The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.

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Intramuscular injection

Intramuscular (also IM or im) injection is the injection of a substance directly into muscle.

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Intravenous therapy

Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).

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Kidney

The kidneys are two bean-shaped organs present in left and right sides of the body in vertebrates.

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Lens (anatomy)

The lens is a transparent, biconvex structure in the eye that, along with the cornea, helps to refract light to be focused on the retina.

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Lipid

In biology and biochemistry, a lipid is a biomolecule that is soluble in nonpolar solvents.

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Neurosurgery

Neurosurgery, or neurological surgery, is the medical specialty concerned with the prevention, diagnosis, surgical treatment, and rehabilitation of disorders which affect any portion of the nervous system including the brain, spinal cord, peripheral nerves, and extra-cranial cerebrovascular system.

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Nicotinic acetylcholine receptor

Nicotinic acetylcholine receptors, or nAChRs, are receptor proteins that respond to the neurotransmitter acetylcholine.

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Orthostatic hypotension

Orthostatic hypotension, also known as postural hypotension, occurs when a person's blood pressure falls when suddenly standing up from a lying or sitting position.

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Parasympathetic nervous system

The parasympathetic nervous system (PSNS) is one of the two divisions of the autonomic nervous system (a division of the peripheral nervous system (PNS)), the other being the sympathetic nervous system.

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Pulmonary edema

Pulmonary edema is fluid accumulation in the tissue and air spaces of the lungs.

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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Sulfonium

A sulfonium ion, also known as sulphonium ion or sulfanium ion, is a positively charged ion (a "cation") featuring three organic substituents attached to sulfur.

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Sympathetic nervous system

The sympathetic nervous system (SNS) is one of the two main divisions of the autonomic nervous system, the other being the parasympathetic nervous system.

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Tachycardia

Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate.

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United States Adopted Name

United States Adopted Names are unique nonproprietary names assigned to pharmaceuticals marketed in the United States.

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Vasodilation

Vasodilation is the widening of blood vessels.

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Redirects here:

ATC code C02BA01, ATCvet code QC02BA01, Arfonad, C22H25N2OS, Trimetaphan, Trimethaphan, Trimethaphan camsylate.

References

[1] https://en.wikipedia.org/wiki/Trimetaphan_camsilate

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