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22 relations: African trypanosomiasis, Alan Fairlamb, Catalase, Chagas disease, Entamoeba histolytica, Enzyme, Glutathione, Glyoxalase system, Hydrogen peroxide, Kinetoplastida, Leishmania, Leishmaniasis, Oxidative stress, Peroxidase, Peroxide, Polyamine, Reductase, Spermidine, Thioredoxin reductase, Transferase, Trypanosoma, Trypanothione-disulfide reductase.
African trypanosomiasis
African trypanosomiasis, also known as sleeping sickness, is an insect-borne parasitic disease of humans and other animals.
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Alan Fairlamb
Alan Hutchinson Fairlamb, CBE, FRSE, FLS, FMedSci, FRSB (born 30 April 1947, Newcastle upon Tyne, England) is a Wellcome Trust Principal Research Fellow and Professor of Biochemistry in the Division of Biological Chemistry and Drug Discovery at the University of Dundee, Scotland.
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Catalase
Catalase is a common enzyme found in nearly all living organisms exposed to oxygen (such as bacteria, plants, and animals).
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Chagas disease
Chagas disease, also known as American trypanosomiasis, is a tropical parasitic disease caused by the protist Trypanosoma cruzi.
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Entamoeba histolytica
Entamoeba histolytica is an anaerobic parasitic amoebozoan, part of the genus Entamoeba.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Glutathione
Glutathione (GSH) is an important antioxidant in plants, animals, fungi, and some bacteria and archaea.
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Glyoxalase system
The glyoxalase system is a set of enzymes that carry out the detoxification of methylglyoxal and the other reactive aldehydes that are produced as a normal part of metabolism.
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Hydrogen peroxide
Hydrogen peroxide is a chemical compound with the formula.
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Kinetoplastida
Kinetoplastida (or Kinetoplastea, as a class) is a group of flagellated protists belonging to the phylum Euglenozoa, and characterised by the presence of an organelle with a large massed DNA called kinetoplast (hence the name).
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Leishmania
Leishmania is a genus of trypanosomes that are responsible for the disease leishmaniasis.
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Leishmaniasis
Leishmaniasis is a disease caused by parasites of the Leishmania type.
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Oxidative stress
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage.
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Peroxidase
Peroxidases (EC number) are a large family of enzymes that typically catalyze a reaction of the form: For many of these enzymes the optimal substrate is hydrogen peroxide, but others are more active with organic hydroperoxides such as lipid peroxides.
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Peroxide
Peroxide is a compound with the structure R-O-O-R. The O−O group in a peroxide is called the peroxide group or peroxo group.
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Polyamine
A polyamine is an organic compound having more than two amino groups.
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Reductase
A reductase is an enzyme that catalyzes a reduction reaction.
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Spermidine
Spermidine is a polyamine compound found in ribosomes and living tissues, and having various metabolic functions within organisms.
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Thioredoxin reductase
Thioredoxin reductases (TR, TrxR) are the only known enzymes to reduce thioredoxin (Trx).
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Transferase
A transferase is any one of a class of enzymes that enact the transfer of specific functional groups (e.g. a methyl or glycosyl group) from one molecule (called the donor) to another (called the acceptor).
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Trypanosoma
Trypanosoma is a genus of kinetoplastids (class Kinetoplastida), a monophyletic group of unicellular parasitic flagellate protozoa.
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Trypanothione-disulfide reductase
In enzymology, a trypanothione-disulfide reductase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are trypanothione and NADP+, whereas its 3 products are trypanothione disulfide, NADPH, and H+.
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References
[1] https://en.wikipedia.org/wiki/Trypanothione
