37 relations: Acacia, Alkaloid, Amino acid, Aralkylamine N-acetyltransferase, Biological activity, Brain, Chemical compound, CRC Press, Dopamine, Exocytosis, Half-life, In vivo, Indole, Indole-3-acetic acid, Mammal, Melatonin, Metabolism, Microbiota, Mole (unit), Monoamine neurotransmitter, Monoamine oxidase A, Monoamine oxidase B, N-Acetylserotonin, Neuromodulation, Neurotransmitter, Norepinephrine, Organic reaction, Phenethylamine, Psychedelic drug, Serotonin, Serotonin receptor agonist, Serotonin-norepinephrine-dopamine releasing agent, Substituted tryptamine, TAAR1, Trace amine, Tropomyosin receptor kinase B, Tryptophan.
Acacia, commonly known as the wattles or acacias, is a large genus of shrubs and trees in the subfamily Mimosoideae of the pea family Fabaceae.
Alkaloids are a class of naturally occurring chemical compounds that mostly contain basic nitrogen atoms.
Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.
Aralkylamine N-acetyltransferase (AANAT), also known as arylalkylamine N-acetyltransferase or serotonin N-acetyltransferase (SNAT), is an enzyme that is involved in the day/night rhythmic production of melatonin, by modification of serotonin.
In pharmacology, biological activity or pharmacological activity describes the beneficial or adverse effects of a drug on living matter.
The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals.
A chemical compound is a chemical substance composed of many identical molecules (or molecular entities) composed of atoms from more than one element held together by chemical bonds.
The CRC Press, LLC is a publishing group based in the United States that specializes in producing technical books.
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.
Exocytosis is a form of active transport in which a cell transports molecules (e.g., neurotransmitters and proteins) out of the cell (exo- + cytosis) by expelling them through an energy-dependent process.
Half-life (symbol t1⁄2) is the time required for a quantity to reduce to half its initial value.
Studies that are in vivo (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism.
Indole is an aromatic heterocyclic organic compound with formula C8H7N.
Indole-3-acetic acid (IAA, 3-IAA) is the most common, naturally occurring, plant hormone of the auxin class.
Mammals are the vertebrates within the class Mammalia (from Latin mamma "breast"), a clade of endothermic amniotes distinguished from reptiles (including birds) by the possession of a neocortex (a region of the brain), hair, three middle ear bones, and mammary glands.
Melatonin, also known as N-acetyl-5-methoxy tryptamine, is a hormone that is produced by the pineal gland in animals and regulates sleep and wakefulness.
Metabolism (from μεταβολή metabolē, "change") is the set of life-sustaining chemical transformations within the cells of organisms.
A microbiota is an "ecological community of commensal, symbiotic and pathogenic microorganisms" found in and on all multicellular organisms studied to date from plants to animals.
The mole, symbol mol, is the SI unit of amount of substance.
Monoamine neurotransmitters are neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by a two-carbon chain (such as -CH2-CH2-). All monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes.
Monoamine oxidase A, also known as MAO-A, is an enzyme that in humans is encoded by the MAOA gene.
Monoamine oxidase B, also known as MAOB, is an enzyme that in humans is encoded by the MAOB gene.
N-Acetylserotonin (NAS), also known as normelatonin, is a naturally occurring chemical precursor and intermediate in the endogenous production of melatonin from serotonin.
Neuromodulation is the physiological process by which a given neuron uses one or more chemicals to regulate diverse populations of neurons.
Neurotransmitters are endogenous chemicals that enable neurotransmission.
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.
Organic reactions are chemical reactions involving organic compounds.
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine which acts as a central nervous system stimulant in humans.
Psychedelics are a class of drug whose primary action is to trigger psychedelic experiences via serotonin receptor agonism, causing thought and visual/auditory changes, and altered state of consciousness.
Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.
A serotonin receptor agonist is an agonist of one or more serotonin receptors.
A serotonin–norepinephrine-dopamine releasing agent (SNDRA), also known as a triple releasing agent (TRA), is a type of drug which induces the release of serotonin, norepinephrine/epinephrine, and dopamine in the brain and body.
Substituted tryptamines, or serotonin analogues, are organic compounds which may be thought of as being derived from tryptamine itself.
Trace amine-associated receptor 1 (TAAR1) is a trace amine-associated receptor (TAAR) protein that in humans is encoded by the TAAR1 gene.
Trace amines are an endogenous group of trace amine-associated receptor 1 (TAAR1) agonists – and hence, monoaminergic neuromodulators – that are structurally and metabolically related to classical monoamine neurotransmitters.
Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 is a protein that in humans is encoded by the NTRK2 gene.
Tryptophan (symbol Trp or W) is an α-amino acid that is used in the biosynthesis of proteins.