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Type III hypersensitivity

Index Type III hypersensitivity

Type III hypersensitivity occurs when there is accumulation of immune complexes (antigen-antibody complexes) that have not been adequately cleared by innate immune cells, giving rise to an inflammatory response and attraction of leukocytes. [1]

43 relations: Acute proliferative glomerulonephritis, Anaphylatoxin, Antibody, Antigen, Arthritis, Arthus reaction, Blood vessel, Clearance (pharmacology), Complement system, Farmer's lung, Fibrinoid necrosis, Glomerulonephritis, Glomerulus, HBsAg, Henoch–Schönlein purpura, Hepatitis B virus, Histamine, Hives, Hypersensitivity, Immune complex, Immunological memory, Inflammation, Joint, Lysosome, Macrophage, Malaria, Mast cell, Nephritis, Neutrophil, Osmosis, Phagocytosis, Polyarteritis nodosa, Purpura, Reactive arthritis, Rheumatoid arthritis, Serum sickness, Subacute bacterial endocarditis, Systemic lupus erythematosus, Type I hypersensitivity, Type II hypersensitivity, Type IV hypersensitivity, Vasculitis, White blood cell.

Acute proliferative glomerulonephritis

Acute proliferative glomerulonephritis is a disorder of the glomeruli (glomerulonephritis), or small blood vessels in the kidneys.

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Anaphylatoxin

Anaphylatoxins, or complement peptides, are fragments (C3a, C4a and C5a) that are produced as part of the activation of the complement system.

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Antibody

An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.

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Antigen

In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.

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Arthritis

Arthritis is a term often used to mean any disorder that affects joints.

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Arthus reaction

In immunology, the Arthus reaction is a type of local type III hypersensitivity reaction.

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Blood vessel

The blood vessels are the part of the circulatory system, and microcirculation, that transports blood throughout the human body.

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Clearance (pharmacology)

In pharmacology, the clearance is a pharmacokinetic measurement of the volume of plasma from which a substance is completely removed per unit time; the usual units are mL/min.

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Complement system

The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's cell membrane.

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Farmer's lung

Farmer's lung (not to be confused with silo-filler's disease) is a hypersensitivity pneumonitis induced by the inhalation of biologic dusts coming from hay dust or mold spores or any other agricultural products.

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Fibrinoid necrosis

Fibrinoid necrosis is a form of necrosis, or tissue death, in which there is accumulation of amorphous, basic, proteinaceous material in the tissue matrix with a staining pattern reminiscent of fibrin.

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Glomerulonephritis

Glomerulonephritis (GN), also known as glomerular nephritis, is a term used to refer to several kidney diseases (usually affecting both kidneys).

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Glomerulus

Glomerulus is a common term used in anatomy to describe globular structures of entwined vessels, fibers, or neurons.

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HBsAg

HBsAg (also known as the Australia antigen) is the surface antigen of the hepatitis B virus (HBV).

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Henoch–Schönlein purpura

Henoch–Schönlein purpura (HSP) also known as IgA vasculitis, anaphylactoid purpura, purpura rheumatica, and Schönlein–Henoch purpura, is a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children.

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Hepatitis B virus

Hepatitis B virus, abbreviated HBV, is a double stranded DNA virus, a species of the genus Orthohepadnavirus, and a member of the Hepadnaviridae family of viruses.

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Histamine

Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus.

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Hives

Hives, also known as urticaria, is a kind of skin rash with red, raised, itchy bumps.

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Hypersensitivity

Hypersensitivity (also called hypersensitivity reaction or intolerance) refers to undesirable reactions produced by the normal immune system, including allergies and autoimmunity.

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Immune complex

An immune complex, sometimes called an antigen-antibody complex, is a molecule formed from the integral binding of an antibody to a soluble antigen.

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Immunological memory

Immunological memory is the ability of the immune system to quickly and specifically recognize an antigen that the body has previously encountered and initiate a corresponding immune response.

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Joint

A joint or articulation (or articular surface) is the connection made between bones in the body which link the skeletal system into a functional whole.

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Lysosome

A lysosome is a membrane-bound organelle found in nearly all animal cells.

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Macrophage

Macrophages (big eaters, from Greek μακρός (makrós).

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Malaria

Malaria is a mosquito-borne infectious disease affecting humans and other animals caused by parasitic protozoans (a group of single-celled microorganisms) belonging to the Plasmodium type.

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Mast cell

A mast cell (also known as a mastocyte or a labrocyte) is a type of white blood cell.

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Nephritis

Nephritis is inflammation of the kidneys and may involve the glomeruli, tubules, or interstitial tissue surrounding the glomeruli and tubules.

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Neutrophil

Neutrophils (also known as neutrocytes) are the most abundant type of granulocytes and the most abundant (40% to 70%) type of white blood cells in most mammals.

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Osmosis

Osmosis is the spontaneous net movement of solvent molecules through a selectively permeable membrane into a region of higher solute concentration, in the direction that tends to equalize the solute concentrations on the two sides.

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Phagocytosis

In cell biology, phagocytosis is the process by which a cell—often a phagocyte or a protist—engulfs a solid particle to form an internal compartment known as a phagosome.

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Polyarteritis nodosa

Polyarteritis nodosa (PAN), also known as panarteritis nodosa, periarteritis nodosa, Kussmaul disease, or Kussmaul-Maier disease, is a systemic necrotizing inflammation of blood vessels (vasculitis) affecting small- or medium-sized muscular arteries, typically involving the arteries of the kidneys and other internal organs but generally sparing the lungs' circulation.

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Purpura

Purpura is a condition of red or purple discolored spots on the skin that do not blanch on applying pressure.

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Reactive arthritis

Reactive arthritis, formerly known as Reiter's syndrome, is a form of inflammatory arthritis that develops in response to an infection in another part of the body (cross-reactivity).

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Rheumatoid arthritis

Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.

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Serum sickness

Serum sickness in humans is a reaction to proteins in antiserum derived from a non-human animal source, occurring 5–10 days after exposure.

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Subacute bacterial endocarditis

Subacute bacterial endocarditis (also called endocarditis lenta) is a type of endocarditis (more specifically, infective endocarditis).

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Systemic lupus erythematosus

Systemic lupus erythematosus (SLE), also known simply as lupus, is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body.

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Type I hypersensitivity

Type I hypersensitivity (or immediate hypersensitivity) is an allergic reaction provoked by reexposure to a specific type of antigen referred to as an allergen.

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Type II hypersensitivity

In type II hypersensitivity (also tissue-specific, or cytotoxic hypersensitivity) the antibodies produced by the immune response bind to antigens on the patient's own cell surfaces.

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Type IV hypersensitivity

Type 4 hypersensitivity is often called delayed type hypersensitivity as the reaction takes several days to develop.

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Vasculitis

Vasculitis is a group of disorders that destroy blood vessels by inflammation.

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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Redirects here:

Immune complex disease, Immune complex diseases, Immune complex hypersensitivity, T3HS, T3hs, Type 3 hypersensitivity, Type III (immune complex) hypersensitivity, Type III hypersensitivity reaction, Type III immune response.

References

[1] https://en.wikipedia.org/wiki/Type_III_hypersensitivity

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