U1A polyadenylation inhibition element (PIE)

The U1A polyadenylation inhibition element (PIE) is an RNA element which is responsible for the regulation of the length of the polyA tail of the U1A protein pre-mRNA. ^[1]

7 relations: Biomolecular structure, Cis-regulatory element, Conserved sequence, Eukaryote, Polyadenylation, Polynucleotide adenylyltransferase, Three prime untranslated region.

Biomolecular structure

Biomolecular structure is the intricate folded, three-dimensional shape that is formed by a molecule of protein, DNA, or RNA, and that is important to its function.

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Cis-regulatory element

Cis-regulatory elements (CREs) are regions of non-coding DNA which regulate the transcription of neighboring genes.

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In evolutionary biology, conserved sequences are similar or identical sequences in nucleic acids (DNA and RNA) or proteins across species (orthologous sequences) or within a genome (paralogous sequences).

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Eukaryote

Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).

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Polyadenylation

Polyadenylation is the addition of a poly(A) tail to a messenger RNA.

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Polynucleotide adenylyltransferase

In enzymology, a polynucleotide adenylyltransferase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ATP and RNA, whereas its two products are pyrophosphate and RNA with an extra adenosine nucleotide at its 3' end.

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Three prime untranslated region

In molecular genetics, the three prime untranslated region (3'-UTR) is the section of messenger RNA (mRNA) that immediately follows the translation termination codon.

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U1A polyadenylation inhibition element.

References

[1] https://en.wikipedia.org/wiki/U1A_polyadenylation_inhibition_element_(PIE)

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