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28 relations: Adenosine, Biomolecular structure, Conserved sequence, Eukaryote, Gene, Group II intron, Intron, Joan A. Steitz, Messenger RNA, Peptide, Phillip Allen Sharp, Phosphorus, Post-transcriptional modification, Precursor mRNA, Pseudouridine, Ribosomal RNA, Richard J. Roberts, RNA splicing, Saccharomyces cerevisiae, Small nuclear RNA, SnRNP, Spliceosome, Stem-loop, Transesterification, Transfer RNA, U1 spliceosomal RNA, Uridine, Yeast.
Adenosine
Adenosine is both a chemical found in many living systems and a medication.
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Biomolecular structure
Biomolecular structure is the intricate folded, three-dimensional shape that is formed by a molecule of protein, DNA, or RNA, and that is important to its function.
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Conserved sequence
In evolutionary biology, conserved sequences are similar or identical sequences in nucleic acids (DNA and RNA) or proteins across species (orthologous sequences) or within a genome (paralogous sequences).
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Eukaryote
Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Group II intron
Group II introns are a large class of self-catalytic ribozymes and mobile genetic elements found within the genes of all three domains of life.
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Intron
An intron is any nucleotide sequence within a gene that is removed by RNA splicing during maturation of the final RNA product.
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Joan A. Steitz
Joan Elaine Argetsinger Steitz (born January 26, 1941) is Sterling Professor of Molecular Biophysics and Biochemistry at Yale University and Investigator at the Howard Hughes Medical Institute.
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Messenger RNA
Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
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Peptide
Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.
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Phillip Allen Sharp
Phillip Allen Sharp (born June 6, 1944) is an American geneticist and molecular biologist who co-discovered RNA splicing.
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Phosphorus
Phosphorus is a chemical element with symbol P and atomic number 15.
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Post-transcriptional modification
Post-transcriptional modification or Co-transcriptional modification is the process in eukaryotic cells where primary transcript RNA is converted into mature RNA.
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Precursor mRNA
Precursor mRNA (pre-mRNA) is an immature single strand of messenger ribonucleic acid (mRNA).
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Pseudouridine
Pseudouridine (abbreviated by the Greek letter psi- Ψ or the letter Q) is an isomer of the nucleoside uridine in which the uracil is attached via a carbon-carbon instead of a nitrogen-carbon glycosidic bond.
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Ribosomal RNA
Ribosomal ribonucleic acid (rRNA) is the RNA component of the ribosome, and is essential for protein synthesis in all living organisms.
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Richard J. Roberts
Sir Richard John Roberts (born 6 September 1943) is an English biochemist and molecular biologist.
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RNA splicing
In molecular biology, splicing is the editing of the nascent precursor messenger RNA (pre-mRNA) transcript into a mature messenger RNA (mRNA).
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Saccharomyces cerevisiae
Saccharomyces cerevisiae is a species of yeast.
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Small nuclear RNA
Small nuclear ribonucleic acid (snRNA), also commonly referred to as U-RNA, is a class of small RNA molecules that are found within the splicing speckles and Cajal bodies of the cell nucleus in eukaryotic cells.
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SnRNP
snRNPs (pronounced "snurps"), or small nuclear ribonucleoproteins, are RNA-protein complexes that combine with unmodified pre-mRNA and various other proteins to form a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs.
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Spliceosome
A spliceosome is a large and complex molecular machine found primarily within the splicing speckles of the cell nucleus of eukaryotic cells.
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Stem-loop
Stem-loop intramolecular base pairing is a pattern that can occur in single-stranded DNA or, more commonly, in RNA.
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Transesterification
In organic chemistry, transesterfication is the process of exchanging the organic group R″ of an ester with the organic group R′ of an alcohol.
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Transfer RNA
A transfer RNA (abbreviated tRNA and formerly referred to as sRNA, for soluble RNA) is an adaptor molecule composed of RNA, typically 76 to 90 nucleotides in length, that serves as the physical link between the mRNA and the amino acid sequence of proteins.
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U1 spliceosomal RNA
U1 spliceosomal RNA is the small nuclear RNA (snRNA) component of U1 snRNP (small nuclear ribonucleoprotein), an RNA-protein complex that combines with other snRNPs, unmodified pre-mRNA, and various other proteins to assemble a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs.
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Uridine
Uridine is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, a ribofuranose) via a β-N1-glycosidic bond.
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Yeast
Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom.
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References
[1] https://en.wikipedia.org/wiki/U2_spliceosomal_RNA
