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31 relations: Adenosine triphosphate, Adenylylation, Apoptosis, Biodegradation, C-terminus, Cancer, Cell cycle, Chromosome, Cysteine, Endocytosis, Enzyme, Eukaryote, Exon, Gene, Helix, Mutation, N-terminus, NEDD8, Protein dimer, Protein domain, Protein folding, Proteolysis, PYR-41, Signal transduction, Spinal muscular atrophy, Stress (biology), SUMO protein, Thioester, UBE1L2, Ubiquitin, X-linked spinal muscular atrophy type 2.
Adenosine triphosphate
Adenosine triphosphate (ATP) is a complex organic chemical that participates in many processes.
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Adenylylation
Adenylylation, now known as AMPylation, is a process in which adenosine monophosphate (AMP) molecule is covalently attached to a protein side chain, altering the function of the protein.
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Apoptosis
Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.
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Biodegradation
Biodegradation is the disintegration of materials by bacteria, fungi, or other biological means.
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C-terminus
The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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Cell cycle
The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.
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Chromosome
A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.
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Cysteine
Cysteine (symbol Cys or C) is a semi-essential proteinogenic amino acid with the formula HO2CCH(NH2)CH2SH.
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Endocytosis
Endocytosis is a form of bulk transport in which a cell transports molecules (such as proteins) into the cell (endo- + cytosis) by engulfing them in an energy-using process.
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Enzyme
Enzymes are macromolecular biological catalysts.
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Eukaryote
Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).
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Exon
An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Helix
A helix, plural helixes or helices, is a type of smooth space curve, i.e. a curve in three-dimensional space.
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Mutation
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.
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N-terminus
The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.
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NEDD8
NEDD8 is a protein that in humans is encoded by the NEDD8 gene.
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Protein dimer
In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are usually non-covalently bound.
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Protein domain
A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.
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Protein folding
Protein folding is the physical process by which a protein chain acquires its native 3-dimensional structure, a conformation that is usually biologically functional, in an expeditious and reproducible manner.
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Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids.
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PYR-41
PYR-41 is the first cell permeable inhibitor of ubiquitin-activating enzyme E1, irreversibly inhibits ubiquitin-activating enzyme activity.It is a pyrazone compound that showed little or no activity on E2, E3.
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Signal transduction
Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular response.
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Spinal muscular atrophy
Spinal muscular atrophy (SMA) is a rare neuromuscular disorder characterised by loss of motor neurons and progressive muscle wasting, often leading to early death.
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Stress (biology)
Physiological or biological stress is an organism's response to a stressor such as an environmental condition.
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SUMO protein
Small Ubiquitin-like Modifier (or SUMO) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function.
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Thioester
In chemistry thioesters are compounds with the functional group R–S–CO–R'.
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UBE1L2
Ubiquitin-like modifier-activating enzyme 6 is a protein that in humans is encoded by the UBA6 gene.
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Ubiquitin
Ubiquitin is a small (8.5 kDa) regulatory protein found in most tissues of eukaryotic organisms, i.e. it occurs ''ubiquitously''.
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X-linked spinal muscular atrophy type 2
X-linked spinal muscular atrophy type 2 (SMAX2, XLSMA), also known as arthrogryposis multiplex congenita X-linked type 1 (AMCX1), is a rare neurological disorder involving death of motor neurons in the anterior horn of spinal cord resulting in generalised muscle wasting (atrophy).
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References
[1] https://en.wikipedia.org/wiki/UBA1
