Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Android™ device!
Download
Faster access than browser!
 

UBA2

Index UBA2

Ubiquitin-like 1-activating enzyme E1B (UBLE1B) also known as SUMO-activating enzyme subunit 2 (SAE2) is an enzyme that in humans is encoded by the UBA2 gene. [1]

59 relations: Adenylylation, Antibody, Apoptosis, Auditory brainstem response, Blood plasma, Budding, Cell cycle, Cell nucleus, Citrobacter, Clinical chemistry, Coding region, Complementary DNA, Dominance (genetics), Dual-energy X-ray absorptiometry, Enzyme, Gene, Glucose tolerance test, Hematology, Hot plate test, Indirect calorimetry, International Knockout Mouse Consortium, Knockout mouse, Lumbar, Mdm2, Meiosis, Micronucleus test, Model organism, Mutant, NF-κB, Nuclear localization sequence, Nucleolus, Open field (animal test), P53, Peripheral blood lymphocyte, Phenotypic screening, Proteasome, Protein dimer, Protein domain, Protein subunit, Protein–protein interaction, Pyrophosphate, Radiography, Sacrum, SAE1, Salmonella, Sequence homology, Small ubiquitin-related modifier 1, Spermatogenesis, SUMO protein, Teratology, ..., Thioester, Transcription factor, Tumor suppressor, UBE2I, Ubiquitin, Ubiquitin-activating enzyme, Weaning, Wellcome Sanger Institute, Zygosity. Expand index (9 more) »

Adenylylation

Adenylylation, now known as AMPylation, is a process in which adenosine monophosphate (AMP) molecule is covalently attached to a protein side chain, altering the function of the protein.

New!!: UBA2 and Adenylylation · See more »

Antibody

An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein produced mainly by plasma cells that is used by the immune system to neutralize pathogens such as pathogenic bacteria and viruses.

New!!: UBA2 and Antibody · See more »

Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

New!!: UBA2 and Apoptosis · See more »

Auditory brainstem response

The auditory brainstem response (ABR) is an auditory evoked potential extracted from ongoing electrical activity in the brain and recorded via electrodes placed on the scalp.

New!!: UBA2 and Auditory brainstem response · See more »

Blood plasma

Blood plasma is a yellowish coloured liquid component of blood that normally holds the blood cells in whole blood in suspension; this makes plasma the extracellular matrix of blood cells.

New!!: UBA2 and Blood plasma · See more »

Budding

Budding is a type of asexual reproduction in which a new organism develops from an outgrowth or bud due to cell division at one particular site.

New!!: UBA2 and Budding · See more »

Cell cycle

The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.

New!!: UBA2 and Cell cycle · See more »

Cell nucleus

In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.

New!!: UBA2 and Cell nucleus · See more »

Citrobacter

Citrobacter is a genus of Gram-negative coliform bacteria in the Enterobacteriaceae family.

New!!: UBA2 and Citrobacter · See more »

Clinical chemistry

Clinical chemistry (also known as chemical pathology, clinical biochemistry or medical biochemistry) is the area of chemistry that is generally concerned with analysis of bodily fluids for diagnostic and therapeutic purposes.

New!!: UBA2 and Clinical chemistry · See more »

Coding region

The coding region of a gene, also known as the CDS (from CoDing Sequence), is that portion of a gene's DNA or RNA that codes for protein.

New!!: UBA2 and Coding region · See more »

Complementary DNA

In genetics, complementary DNA (cDNA) is DNA synthesized from a single stranded RNA (e.g., messenger RNA (mRNA) or microRNA) template in a reaction catalyzed by the enzyme reverse transcriptase.

New!!: UBA2 and Complementary DNA · See more »

Dominance (genetics)

Dominance in genetics is a relationship between alleles of one gene, in which the effect on phenotype of one allele masks the contribution of a second allele at the same locus.

New!!: UBA2 and Dominance (genetics) · See more »

Dual-energy X-ray absorptiometry

Dual-energy X-ray absorptiometry (DXA, previously DEXA) is a means of measuring bone mineral density (BMD).

New!!: UBA2 and Dual-energy X-ray absorptiometry · See more »

Enzyme

Enzymes are macromolecular biological catalysts.

New!!: UBA2 and Enzyme · See more »

Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

New!!: UBA2 and Gene · See more »

Glucose tolerance test

The glucose tolerance test is a medical test in which glucose is given and blood samples taken afterward to determine how quickly it is cleared from the blood.

New!!: UBA2 and Glucose tolerance test · See more »

Hematology

Hematology, also spelled haematology, is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood.

New!!: UBA2 and Hematology · See more »

Hot plate test

The hot plate test is a test of the pain response in animals, similar to the tail flick test.

New!!: UBA2 and Hot plate test · See more »

Indirect calorimetry

Indirect calorimetry calculates heat that living organisms produce by measuring either their production of carbon dioxide and nitrogen waste (frequently ammonia in aquatic organisms, or urea in terrestrial ones), or from their consumption of oxygen.

New!!: UBA2 and Indirect calorimetry · See more »

International Knockout Mouse Consortium

The International Knockout Mouse Consortium (IKMC) is a scientific endeavour to produce a collection of mouse embryonic stem cell lines that together lack every gene in the genome, and then to distribute the cells to scientific researchers to create knockout mice to study.

New!!: UBA2 and International Knockout Mouse Consortium · See more »

Knockout mouse

A knockout mouse or knock-out mouse is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA.

New!!: UBA2 and Knockout mouse · See more »

Lumbar

In tetrapod anatomy, lumbar is an adjective that means of or pertaining to the abdominal segment of the torso, between the diaphragm and the sacrum. The lumbar region is sometimes referred to as the lower spine, or as an area of the back in its proximity.

New!!: UBA2 and Lumbar · See more »

Mdm2

Mouse double minute 2 homolog (MDM2) also known as E3 ubiquitin-protein ligase Mdm2 is a protein that in humans is encoded by the MDM2 gene.

New!!: UBA2 and Mdm2 · See more »

Meiosis

Meiosis (from Greek μείωσις, meiosis, which means lessening) is a specialized type of cell division that reduces the chromosome number by half, creating four haploid cells, each genetically distinct from the parent cell that gave rise to them.

New!!: UBA2 and Meiosis · See more »

Micronucleus test

A micronucleus test is a test used in toxicological screening for potential genotoxic compounds.

New!!: UBA2 and Micronucleus test · See more »

Model organism

A model organism is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the organism model will provide insight into the workings of other organisms.

New!!: UBA2 and Model organism · See more »

Mutant

In biology and especially genetics, a mutant is an organism or a new genetic character arising or resulting from an instance of mutation, which is an alteration of the DNA sequence of a gene or chromosome of an organism.

New!!: UBA2 and Mutant · See more »

NF-κB

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival.

New!!: UBA2 and NF-κB · See more »

Nuclear localization sequence

A nuclear localization signal or sequence (NLS) is an amino acid sequence that 'tags' a protein for import into the cell nucleus by nuclear transport.

New!!: UBA2 and Nuclear localization sequence · See more »

Nucleolus

The nucleolus (plural nucleoli) is the largest structure in the nucleus of eukaryotic cells.

New!!: UBA2 and Nucleolus · See more »

Open field (animal test)

Developed by Calvin S. Hall, the open field test is an experimental test used to assay general locomotor activity levels, anxiety, and willingness to explore in animals (usually rodents) in scientific research.

New!!: UBA2 and Open field (animal test) · See more »

P53

Tumor protein p53, also known as p53, cellular tumor antigen p53 (UniProt name), phosphoprotein p53, tumor suppressor p53, antigen NY-CO-13, or transformation-related protein 53 (TRP53), is any isoform of a protein encoded by homologous genes in various organisms, such as TP53 (humans) and Trp53 (mice).

New!!: UBA2 and P53 · See more »

Peripheral blood lymphocyte

Peripheral blood lymphocytes (PBL) are mature lymphocytes that circulate in the blood, rather than localising to organs (such as the spleen or lymph nodes).

New!!: UBA2 and Peripheral blood lymphocyte · See more »

Phenotypic screening

Phenotypic screening is a type of screening used in biological research and drug discovery to identify substances such as small molecules, peptides, or RNAi that alter the phenotype of a cell or an organism in a desired manner.

New!!: UBA2 and Phenotypic screening · See more »

Proteasome

Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds.

New!!: UBA2 and Proteasome · See more »

Protein dimer

In biochemistry, a protein dimer is a macromolecular complex formed by two protein monomers, or single proteins, which are usually non-covalently bound.

New!!: UBA2 and Protein dimer · See more »

Protein domain

A protein domain is a conserved part of a given protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the protein chain.

New!!: UBA2 and Protein domain · See more »

Protein subunit

In structural biology, a protein subunit is a single protein molecule that assembles (or "coassembles") with other protein molecules to form a protein complex.

New!!: UBA2 and Protein subunit · See more »

Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

New!!: UBA2 and Protein–protein interaction · See more »

Pyrophosphate

In chemistry, a pyrophosphate is a phosphorus oxyanion.

New!!: UBA2 and Pyrophosphate · See more »

Radiography

Radiography is an imaging technique using X-rays to view the internal form of an object.

New!!: UBA2 and Radiography · See more »

Sacrum

The sacrum (or; plural: sacra or sacrums) in human anatomy is a large, triangular bone at the base of the spine, that forms by the fusing of sacral vertebrae S1S5 between 18 and 30years of age.

New!!: UBA2 and Sacrum · See more »

SAE1

SUMO-activating enzyme subunit 1 is a protein that in humans is encoded by the SAE1 gene.

New!!: UBA2 and SAE1 · See more »

Salmonella

Salmonella is a genus of rod-shaped (bacillus) Gram-negative bacteria of the family Enterobacteriaceae.

New!!: UBA2 and Salmonella · See more »

Sequence homology

Sequence homology is the biological homology between DNA, RNA, or protein sequences, defined in terms of shared ancestry in the evolutionary history of life.

New!!: UBA2 and Sequence homology · See more »

Small ubiquitin-related modifier 1

Small ubiquitin-related modifier 1 is a protein that in humans is encoded by the SUMO1 gene.

New!!: UBA2 and Small ubiquitin-related modifier 1 · See more »

Spermatogenesis

Spermatogenesis is the process by which haploid spermatozoa develop from germ cells in the seminiferous tubules of the testis.

New!!: UBA2 and Spermatogenesis · See more »

SUMO protein

Small Ubiquitin-like Modifier (or SUMO) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function.

New!!: UBA2 and SUMO protein · See more »

Teratology

Teratology is the study of abnormalities of physiological development.

New!!: UBA2 and Teratology · See more »

Thioester

In chemistry thioesters are compounds with the functional group R–S–CO–R'.

New!!: UBA2 and Thioester · See more »

Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

New!!: UBA2 and Transcription factor · See more »

Tumor suppressor

A tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer.

New!!: UBA2 and Tumor suppressor · See more »

UBE2I

SUMO-conjugating enzyme UBC9 is an enzyme that in humans is encoded by the UBE2I gene.

New!!: UBA2 and UBE2I · See more »

Ubiquitin

Ubiquitin is a small (8.5 kDa) regulatory protein found in most tissues of eukaryotic organisms, i.e. it occurs ''ubiquitously''.

New!!: UBA2 and Ubiquitin · See more »

Ubiquitin-activating enzyme

Ubiquitin-activating enzymes, also known as E1 enzymes, catalyze the first step in the ubiquitination reaction, which (among other things) can target a protein for degradation via a proteasome.

New!!: UBA2 and Ubiquitin-activating enzyme · See more »

Weaning

Weaning is the process of gradually introducing an infant mammal to what will be its adult diet and withdrawing the supply of its mother's milk.

New!!: UBA2 and Weaning · See more »

Wellcome Sanger Institute

The Wellcome Sanger Institute, previously known as The Sanger Centre and Wellcome Trust Sanger Institute, is a non-profit British genomics and genetics research institute, primarily funded by the Wellcome Trust.

New!!: UBA2 and Wellcome Sanger Institute · See more »

Zygosity

Zygosity is the degree of similarity of the alleles for a trait in an organism.

New!!: UBA2 and Zygosity · See more »

Redirects here:

UBA2 (gene), Uba2.

References

[1] https://en.wikipedia.org/wiki/UBA2

OutgoingIncoming
Hey! We are on Facebook now! »