Logo
Unionpedia
Communication
Get it on Google Play
New! Download Unionpedia on your Android™ device!
Free
Faster access than browser!
 

Ubiquitin-conjugating enzyme

Index Ubiquitin-conjugating enzyme

Ubiquitin-conjugating enzymes, also known as E2 enzymes and more rarely as ubiquitin-carrier enzymes, perform the second step in the ubiquitination reaction that targets a protein for degradation via the proteasome. [1]

42 relations: Active site, Adenosine triphosphate, Amino acid, BIRC6, Cell (biology), Conserved sequence, Covalent bond, Cysteine, Denaturation (biochemistry), Lysine, Peptide, Protease, Proteasome, Protein, Protein–protein interaction, Substrate (chemistry), UBE2A, UBE2B, UBE2C, UBE2D1, UBE2D2, UBE2D3, UBE2E1, UBE2E2, UBE2E3, UBE2G1, UBE2G2, UBE2H, UBE2I, UBE2J1, UBE2L3, UBE2L6, UBE2M, UBE2N, UBE2O, UBE2R2, UBE2V1, UBE2V2, UBE2Z, Ubiquitin, Ubiquitin ligase, Ubiquitin-activating enzyme.

Active site

In biology, the active site is the region of an enzyme where substrate molecules bind and undergo a chemical reaction.

New!!: Ubiquitin-conjugating enzyme and Active site · See more »

Adenosine triphosphate

Adenosine triphosphate (ATP) is a complex organic chemical that participates in many processes.

New!!: Ubiquitin-conjugating enzyme and Adenosine triphosphate · See more »

Amino acid

Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid.

New!!: Ubiquitin-conjugating enzyme and Amino acid · See more »

BIRC6

Baculoviral IAP repeat-containing protein 6 is a protein that in humans is encoded by the BIRC6 gene.

New!!: Ubiquitin-conjugating enzyme and BIRC6 · See more »

Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

New!!: Ubiquitin-conjugating enzyme and Cell (biology) · See more »

Conserved sequence

In evolutionary biology, conserved sequences are similar or identical sequences in nucleic acids (DNA and RNA) or proteins across species (orthologous sequences) or within a genome (paralogous sequences).

New!!: Ubiquitin-conjugating enzyme and Conserved sequence · See more »

Covalent bond

A covalent bond, also called a molecular bond, is a chemical bond that involves the sharing of electron pairs between atoms.

New!!: Ubiquitin-conjugating enzyme and Covalent bond · See more »

Cysteine

Cysteine (symbol Cys or C) is a semi-essential proteinogenic amino acid with the formula HO2CCH(NH2)CH2SH.

New!!: Ubiquitin-conjugating enzyme and Cysteine · See more »

Denaturation (biochemistry)

Denaturation is a process in which proteins or nucleic acids lose the quaternary structure, tertiary structure, and secondary structure which is present in their native state, by application of some external stress or compound such as a strong acid or base, a concentrated inorganic salt, an organic solvent (e.g., alcohol or chloroform), radiation or heat.

New!!: Ubiquitin-conjugating enzyme and Denaturation (biochemistry) · See more »

Lysine

Lysine (symbol Lys or K) is an α-amino acid that is used in the biosynthesis of proteins.

New!!: Ubiquitin-conjugating enzyme and Lysine · See more »

Peptide

Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.

New!!: Ubiquitin-conjugating enzyme and Peptide · See more »

Protease

A protease (also called a peptidase or proteinase) is an enzyme that performs proteolysis: protein catabolism by hydrolysis of peptide bonds.

New!!: Ubiquitin-conjugating enzyme and Protease · See more »

Proteasome

Proteasomes are protein complexes which degrade unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds.

New!!: Ubiquitin-conjugating enzyme and Proteasome · See more »

Protein

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

New!!: Ubiquitin-conjugating enzyme and Protein · See more »

Protein–protein interaction

Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.

New!!: Ubiquitin-conjugating enzyme and Protein–protein interaction · See more »

Substrate (chemistry)

In chemistry, a substrate is typically the chemical species being observed in a chemical reaction, which reacts with a reagent to generate a product.

New!!: Ubiquitin-conjugating enzyme and Substrate (chemistry) · See more »

UBE2A

Ubiquitin-conjugating enzyme E2 A is a protein that in humans is encoded by the UBE2A gene.

New!!: Ubiquitin-conjugating enzyme and UBE2A · See more »

UBE2B

Ubiquitin-conjugating enzyme E2 B is a protein that in humans is encoded by the UBE2B gene.

New!!: Ubiquitin-conjugating enzyme and UBE2B · See more »

UBE2C

Ubiquitin-conjugating enzyme E2 C is a protein that in humans is encoded by the UBE2C gene.

New!!: Ubiquitin-conjugating enzyme and UBE2C · See more »

UBE2D1

Ubiquitin-conjugating enzyme E2 D1 is a protein that in humans is encoded by the UBE2D1 gene.

New!!: Ubiquitin-conjugating enzyme and UBE2D1 · See more »

UBE2D2

Ubiquitin-conjugating enzyme E2 D2 is a protein that in humans is encoded by the UBE2D2 gene.

New!!: Ubiquitin-conjugating enzyme and UBE2D2 · See more »

UBE2D3

Ubiquitin-conjugating enzyme E2 D3 is a protein that in humans is encoded by the UBE2D3 gene.

New!!: Ubiquitin-conjugating enzyme and UBE2D3 · See more »

UBE2E1

Ubiquitin-conjugating enzyme E2 E1 is a protein that in humans is encoded by the UBE2E1 gene.

New!!: Ubiquitin-conjugating enzyme and UBE2E1 · See more »

UBE2E2

Ubiquitin-conjugating enzyme E2 E2 is a protein that in humans is encoded by the UBE2E2 gene.

New!!: Ubiquitin-conjugating enzyme and UBE2E2 · See more »

UBE2E3

Ubiquitin-conjugating enzyme E2 E3 is a protein that in humans is encoded by the UBE2E3 gene.

New!!: Ubiquitin-conjugating enzyme and UBE2E3 · See more »

UBE2G1

Ubiquitin-conjugating enzyme E2 G1 is a protein that in humans is encoded by the UBE2G1 gene.

New!!: Ubiquitin-conjugating enzyme and UBE2G1 · See more »

UBE2G2

Ubiquitin-conjugating enzyme E2 G2 is a protein that in humans is encoded by the UBE2G2 gene.

New!!: Ubiquitin-conjugating enzyme and UBE2G2 · See more »

UBE2H

Ubiquitin-conjugating enzyme E2 H is a protein that in humans is encoded by the UBE2H gene.

New!!: Ubiquitin-conjugating enzyme and UBE2H · See more »

UBE2I

SUMO-conjugating enzyme UBC9 is an enzyme that in humans is encoded by the UBE2I gene.

New!!: Ubiquitin-conjugating enzyme and UBE2I · See more »

UBE2J1

Ubiquitin-conjugating enzyme E2 J1 is a protein that in humans is encoded by the UBE2J1 gene.

New!!: Ubiquitin-conjugating enzyme and UBE2J1 · See more »

UBE2L3

Ubiquitin-conjugating enzyme E2 L3 (UBE2L3), also called UBCH7, is a protein that in humans is encoded by the UBE2L3 gene.

New!!: Ubiquitin-conjugating enzyme and UBE2L3 · See more »

UBE2L6

Ubiquitin/ISG15-conjugating enzyme E2 L6 is a protein that in humans is encoded by the UBE2L6 gene.

New!!: Ubiquitin-conjugating enzyme and UBE2L6 · See more »

UBE2M

NEDD8-conjugating enzyme Ubc12 is a protein that in humans is encoded by the UBE2M gene.

New!!: Ubiquitin-conjugating enzyme and UBE2M · See more »

UBE2N

Ubiquitin-conjugating enzyme E2 N is a protein that in humans is encoded by the UBE2N gene.

New!!: Ubiquitin-conjugating enzyme and UBE2N · See more »

UBE2O

Ubiquitin-conjugating enzyme E2 O is a protein that in humans is encoded by the UBE2O gene.

New!!: Ubiquitin-conjugating enzyme and UBE2O · See more »

UBE2R2

Ubiquitin-conjugating enzyme E2 R2 is a protein that in humans is encoded by the UBE2R2 gene.

New!!: Ubiquitin-conjugating enzyme and UBE2R2 · See more »

UBE2V1

Ubiquitin-conjugating enzyme E2 variant 1 is a protein that in humans is encoded by the UBE2V1 gene.

New!!: Ubiquitin-conjugating enzyme and UBE2V1 · See more »

UBE2V2

Ubiquitin-conjugating enzyme E2 variant 2 is a protein that in humans is encoded by the UBE2V2 gene.

New!!: Ubiquitin-conjugating enzyme and UBE2V2 · See more »

UBE2Z

Ubiquitin conjugating enzyme E2 Z (UBE2Z), also known as UBA6-specific E2 enzyme 1 (USE1), is an enzyme that in humans is encoded by the UBE2Z gene on chromosome 17.

New!!: Ubiquitin-conjugating enzyme and UBE2Z · See more »

Ubiquitin

Ubiquitin is a small (8.5 kDa) regulatory protein found in most tissues of eukaryotic organisms, i.e. it occurs ''ubiquitously''.

New!!: Ubiquitin-conjugating enzyme and Ubiquitin · See more »

Ubiquitin ligase

A ubiquitin ligase (also called an E3 ubiquitin ligase) is a protein that recruits an E2 ubiquitin-conjugating enzyme that has been loaded with ubiquitin, recognizes a protein substrate, and assists or directly catalyzes the transfer of ubiquitin from the E2 to the protein substrate.

New!!: Ubiquitin-conjugating enzyme and Ubiquitin ligase · See more »

Ubiquitin-activating enzyme

Ubiquitin-activating enzymes, also known as E1 enzymes, catalyze the first step in the ubiquitination reaction, which (among other things) can target a protein for degradation via a proteasome.

New!!: Ubiquitin-conjugating enzyme and Ubiquitin-activating enzyme · See more »

Redirects here:

E2 enzyme.

References

[1] https://en.wikipedia.org/wiki/Ubiquitin-conjugating_enzyme

OutgoingIncoming
Hey! We are on Facebook now! »