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Index Vilaprisan

Vilaprisan (INN, USAN) (developmental code name BAY-1002670) is a synthetic, steroidal selective progesterone receptor modulator (SPRM) which is under development by Bayer HealthCare Pharmaceuticals for the treatment of endometriosis and uterine fibroids. [1]

18 relations: Bayer, Binding selectivity, Clinical trial, Endometriosis, International nonproprietary name, Lonaprisan, Mifepristone, Onapristone, Oral administration, Organic compound, Partial agonist, Potency (pharmacology), Progesterone receptor, Selective progesterone receptor modulator, Steroid, Ulipristal acetate, United States Adopted Name, Uterine fibroid.


Bayer AG is a German multinational, pharmaceutical and life sciences company.

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Binding selectivity

Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.

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Clinical trial

Clinical trials are experiments or observations done in clinical research.

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Endometriosis is a condition in which the endometrium, the layer of tissue that normally covers the inside of the uterus, grows outside of it.

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International nonproprietary name

The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.

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Lonaprisan (INN, USAN) (developmental code names ZK-230211, BAY 86-5044, ZK-PRA) is a synthetic, steroidal antiprogestogen which was under development by Bayer HealthCare Pharmaceuticals for the treatment of endometriosis, dysmenorrhea, and breast cancer but was discontinued.

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Mifepristone, also known as RU-486, is a medication typically used in combination with misoprostol, to bring about an abortion.

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Onapristone (INN) (developmental code names ZK-89299, ZK-299) is a synthetic, steroidal antiprogestogen with additional antiglucocorticoid activity which was developed by Schering and described in 1984 but was never marketed.

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Oral administration

| name.

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Organic compound

In chemistry, an organic compound is generally any chemical compound that contains carbon.

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Partial agonist

In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.

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Potency (pharmacology)

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

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Progesterone receptor

The progesterone receptor (PR), also known as NR3C3 or nuclear receptor subfamily 3, group C, member 3, is a protein found inside cells.

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Selective progesterone receptor modulator

A selective progesterone receptor modulator (SPRM) is an agent that acts on the progesterone receptor.

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A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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Ulipristal acetate

Ulipristal acetate, sold under the brand name Ella among others, is a medication used for emergency birth control and uterine fibroids.

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United States Adopted Name

United States Adopted Names are unique nonproprietary names assigned to pharmaceuticals marketed in the United States.

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Uterine fibroid

Uterine fibroids, also known as uterine leiomyomas or fibroids, are benign smooth muscle tumors of the uterus.

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Redirects here:

BAY 1002670, BAY-1002670, BAY1002670.


[1] https://en.wikipedia.org/wiki/Vilaprisan

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