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44 relations: Acetone, Acetonitrile, Aciclovir, Antiviral drug, Aqueous humour, Area under the curve (pharmacokinetics), Base pair, Bioaccumulation, Biotransformation, Blood plasma, Cmax (pharmacology), Cochrane (organisation), Concentrative nucleoside transporter 1, Cornea, Deoxyuridine, Diethyl ether, Diisopropyl ether, DNA replication, Drugs.com, Edema, Equilibrative nucleoside transporter 1, Equilibrative nucleoside transporter 2, Ethanol, GlaxoSmithKline, Glucuronidation, Herpes simplex virus, Herpesviridae, Human eye, Idoxuridine, In vitro, Isopropyl alcohol, Keratitis, Keratoconjunctivitis, King Pharmaceuticals, Methanol, Molar concentration, Nucleoside analogue, Thymidine phosphorylase, Tipiracil, Trifluridine/tipiracil, Uracil, Vaccinia, Vidarabine, Zidovudine.
Acetone
Acetone (systematically named propanone) is the organic compound with the formula (CH3)2CO.
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Acetonitrile
Acetonitrile is the chemical compound with the formula.
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Aciclovir
Aciclovir (ACV), also known as acyclovir, is an antiviral medication.
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Antiviral drug
Antiviral drugs are a class of medication used specifically for treating viral infections rather than bacterial ones.
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Aqueous humour
The aqueous humour is a transparent, watery fluid similar to plasma, but containing low protein concentrations.
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Area under the curve (pharmacokinetics)
In the field of pharmacokinetics, the area under the curve (AUC) is the definite integral in a plot of drug concentration in blood plasma vs.
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Base pair
A base pair (bp) is a unit consisting of two nucleobases bound to each other by hydrogen bonds.
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Bioaccumulation
Bioaccumulation is the accumulation of substances, such as pesticides, or other chemicals in an organism.
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Biotransformation
Biotransformation is the chemical modification (or modifications) made by an organism on a chemical compound.
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Blood plasma
Blood plasma is a yellowish coloured liquid component of blood that normally holds the blood cells in whole blood in suspension; this makes plasma the extracellular matrix of blood cells.
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Cmax (pharmacology)
Cmax is the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been administrated and before the administration of a second dose.
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Cochrane (organisation)
Cochrane is a non-profit, non-governmental organization formed to organize medical research findings so as to facilitate evidence-based choices about health interventions faced by health professionals, patients, and policy makers.
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Concentrative nucleoside transporter 1
Concentrative nucleoside transporter 1 (CNT1) is a protein that in humans is encoded by the SLC28A1 gene.
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Cornea
The cornea is the transparent front part of the eye that covers the iris, pupil, and anterior chamber.
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Deoxyuridine
Deoxyuridine (dU) is a compound and a nucleoside.
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Diethyl ether
Diethyl ether, or simply ether, is an organic compound in the ether class with the formula, sometimes abbreviated as (see Pseudoelement symbols).
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Diisopropyl ether
Diisopropyl ether is secondary ether that is used as a solvent.
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DNA replication
In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule.
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Drugs.com
Drugs.com is an online pharmaceutical encyclopedia which provides drug information for consumers and healthcare professionals, primarily in the USA.
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Edema
Edema, also spelled oedema or œdema, is an abnormal accumulation of fluid in the interstitium, located beneath the skin and in the cavities of the body, which can cause severe pain.
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Equilibrative nucleoside transporter 1
Equilibrative nucleoside transporter 1 (ENT1) is a protein that in humans is encoded by the SLC29A1 gene.
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Equilibrative nucleoside transporter 2
Equilibrative nucleoside transporter 2 (ENT2) is a protein that in humans is encoded by the SLC29A2 gene.
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Ethanol
Ethanol, also called alcohol, ethyl alcohol, grain alcohol, and drinking alcohol, is a chemical compound, a simple alcohol with the chemical formula.
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GlaxoSmithKline
GlaxoSmithKline plc (GSK) is a British pharmaceutical company headquartered in Brentford, London.
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Glucuronidation
Glucuronidation is often involved in drug metabolism of substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids.
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Herpes simplex virus
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as human herpesvirus 1 and 2 (HHV-1 and HHV-2), are two members of the herpesvirus family, Herpesviridae, that infect humans.
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Herpesviridae
Herpesviridae is a large family of DNA viruses that cause diseases in animals, including humans.
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Human eye
The human eye is an organ which reacts to light and pressure.
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Idoxuridine
Idoxuridine is an anti-herpesvirus antiviral drug.
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In vitro
In vitro (meaning: in the glass) studies are performed with microorganisms, cells, or biological molecules outside their normal biological context.
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Isopropyl alcohol
Isopropyl alcohol (IUPAC name propan-2-ol; commonly called isopropanol) is a compound with the chemical formula C3H8O.
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Keratitis
Keratitis is a condition in which the eye's cornea, the clear dome on the front surface of the eye, becomes inflamed.
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Keratoconjunctivitis
Keratoconjunctivitis is inflammation ("-itis") of the cornea and conjunctiva.
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King Pharmaceuticals
King Pharmaceuticals, is a wholly owned subsidiary of Pfizer based in Bristol, Tennessee.
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Methanol
Methanol, also known as methyl alcohol among others, is a chemical with the formula CH3OH (a methyl group linked to a hydroxyl group, often abbreviated MeOH).
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Molar concentration
Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular of a solute in a solution, in terms of amount of substance per unit volume of solution.
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Nucleoside analogue
Nucleoside analogues are nucleosides which contain a nucleic acid analogue and a sugar.
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Thymidine phosphorylase
In enzymology, a thymidine phosphorylase is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are thymidine and phosphate, whereas its two products are thymine and 2-deoxy-alpha-D-ribose 1-phosphate.
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Tipiracil
Tipiracil is a drug used in the treatment of cancer.
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Trifluridine/tipiracil
Trifluridine/tipiracil (trade name Lonsurf) is a combination drug that is used as a third- or fourth-line treatment of metastatic colorectal cancer, after chemotherapy and targeted therapeutics have failed.
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Uracil
Uracil (U) is one of the four nucleobases in the nucleic acid of RNA that are represented by the letters A, G, C and U. The others are adenine (A), cytosine (C), and guanine (G).
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Vaccinia
Vaccinia virus (VACV or VV) is a large, complex, enveloped virus belonging to the poxvirus family.
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Vidarabine
Vidarabine or 9-β-D-arabinofuranosyladenine (ara-A) is an antiviral drug which is active against herpes simplex and varicella zoster viruses.
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Zidovudine
Zidovudine (ZDV), also known as azidothymidine (AZT), is an antiretroviral medication used to prevent and treat HIV/AIDS.
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Redirects here:
ATC code S01AD02, ATCvet code QS01AD02, F3DThd, F3T, F3TDR, Fluridine, TFDU, Trifluorothymidine, Virophta, Viroptic.
References
[1] https://en.wikipedia.org/wiki/Trifluridine
