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Index Virotherapy

Virotherapy is a treatment using biotechnology to convert viruses into therapeutic agents by reprogramming viruses to treat diseases. [1]

40 relations: Angiogenesis, Antigen, Biotechnology, Cancer, Chester M. Southam, Clinical trial, Common cold, Dopamine, ECHO-7, Echovirus, Eye, Gene therapy, Glioblastoma, Hebrew University of Jerusalem, Herpes simplex virus, Immune privilege, Immunotherapy, Interferon, Lysis, Memorial Sloan Kettering Cancer Center, Necrosis, Neoplasm, Newcastle disease, Oncolytic virus, Oxford BioMedica, Pancreatic cancer, Parkinson's disease, Pexastimogene devacirepvec, ProSavin, Protozoa, Talimogene laherparepvec, The New York Times, Treatment of cancer, University of Texas at Austin, Vaccine, Vector (epidemiology), Viral vector, Virosome, Virus, Wild type.


Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.

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In immunology, an antigen is a molecule capable of inducing an immune response (to produce an antibody) in the host organism.

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Biotechnology is the broad area of science involving living systems and organisms to develop or make products, or "any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use" (UN Convention on Biological Diversity, Art. 2).

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Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

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Chester M. Southam

Chester M. Southam (October 4, 1919 – April 5, 2002) was an immunologist and oncologist at Memorial Sloan Kettering Cancer Center and Cornell University Medical College; he went to Thomas Jefferson University in 1971 and worked there until the end of his career.

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Clinical trial

Clinical trials are experiments or observations done in clinical research.

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Common cold

The common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory tract that primarily affects the nose.

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Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is an organic chemical of the catecholamine and phenethylamine families that plays several important roles in the brain and body.

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ECHO-7 (trade name: RIGVIR) is a virotherapy drug that was approved by the State Agency of Medicines of the Republic of Latvia in 2004.

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An ECHO (enteric cytopathic human orphan) virus is a type of RNA virus that belongs to the species Enterovirus B, genus Enterovirus of the Picornaviridae family.

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Eyes are organs of the visual system.

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Gene therapy

In the medicine field, gene therapy (also called human gene transfer) is the therapeutic delivery of nucleic acid into a patient's cells as a drug to treat disease.

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Glioblastoma, also known as glioblastoma multiforme (GBM), is the most aggressive cancer that begins within the brain.

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Hebrew University of Jerusalem

The Hebrew University of Jerusalem (האוניברסיטה העברית בירושלים, Ha-Universita ha-Ivrit bi-Yerushalayim; الجامعة العبرية في القدس, Al-Jami'ah al-Ibriyyah fi al-Quds; abbreviated HUJI) is Israel's second oldest university, established in 1918, 30 years before the establishment of the State of Israel.

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Herpes simplex virus

Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as human herpesvirus 1 and 2 (HHV-1 and HHV-2), are two members of the herpesvirus family, Herpesviridae, that infect humans.

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Immune privilege

Certain sites of the human body have immune privilege, meaning they are able to tolerate the introduction of antigens without eliciting an inflammatory immune response.

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Immunotherapy is the "treatment of disease by inducing, enhancing, or suppressing an immune response".

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Interferons (IFNs) are a group of signaling proteins made and released by host cells in response to the presence of several pathogens, such as viruses, bacteria, parasites, and also tumor cells.

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Lysis (Greek λύσις lýsis, "a loosing" from λύειν lýein, "to unbind") refers to the breaking down of the membrane of a cell, often by viral, enzymic, or osmotic (that is, "lytic") mechanisms that compromise its integrity.

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Memorial Sloan Kettering Cancer Center

Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in New York City, founded in 1884 as the New York Cancer Hospital.

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Necrosis (from the Greek νέκρωσις "death, the stage of dying, the act of killing" from νεκρός "dead") is a form of cell injury which results in the premature death of cells in living tissue by autolysis.

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Neoplasia is a type of abnormal and excessive growth of tissue.

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Newcastle disease

Newcastle disease is a contagious viral bird disease affecting many domestic and wild avian species; it is transmissible to humans.

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Oncolytic virus

An oncolytic virus is a virus that preferentially infects and kills cancer cells.

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Oxford BioMedica

Oxford BioMedica (LSE: OXB) is a biopharmaceutical company specialising in the development and commercialisation of gene-based medicines.

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Pancreatic cancer

Pancreatic cancer arises when cells in the pancreas, a glandular organ behind the stomach, begin to multiply out of control and form a mass.

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Parkinson's disease

Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system.

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Pexastimogene devacirepvec

JX-594 is an oncolytic virus (also known as Pexa-Vec, INN pexastimogene devacirepvec) originally constructed in Dr.

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ProSavin is an experimental drug believed to be of use in the treatment of Parkinson's Disease.

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Protozoa (also protozoan, plural protozoans) is an informal term for single-celled eukaryotes, either free-living or parasitic, which feed on organic matter such as other microorganisms or organic tissues and debris.

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Talimogene laherparepvec

Talimogene laherparepvec is a biopharmaceutical drug to treat melanoma lesions that cannot be operated on; it is injected directly into the lesion.

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The New York Times

The New York Times (sometimes abbreviated as The NYT or The Times) is an American newspaper based in New York City with worldwide influence and readership.

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Treatment of cancer

Cancer can be treated by surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy (including immunotherapy such as monoclonal antibody therapy) and synthetic lethality.

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University of Texas at Austin

The University of Texas at Austin (UT, UT Austin, or Texas) is a public research university and the flagship institution of the University of Texas System.

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A vaccine is a biological preparation that provides active acquired immunity to a particular disease.

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Vector (epidemiology)

In epidemiology, a disease vector is any agent that carries and transmits an infectious pathogen into another living organism; most agents regarded as vectors are organisms, such as intermediate parasites or microbes, but it could be an inanimate medium of infection such as dust particles.

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Viral vector

Viral vectors are tools commonly used by molecular biologists to deliver genetic material into cells.

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A virosome is a drug or vaccine delivery mechanism consisting of unilamellar phospholipid membrane (either a mono- or bi-layer) vesicle incorporating virus derived proteins to allow the virosomes to fuse with target cells.

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A virus is a small infectious agent that replicates only inside the living cells of other organisms.

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Wild type

Wild type (WT) refers to the phenotype of the typical form of a species as it occurs in nature.

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Viral therapy.


[1] https://en.wikipedia.org/wiki/Virotherapy

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