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Voltage-gated potassium channel

Index Voltage-gated potassium channel

Voltage-gated potassium channels (VGKCs) are transmembrane channels specific for potassium and sensitive to voltage changes in the cell's membrane potential. [1]

71 relations: Action potential, Alpha helix, Ball and chain inactivation, Calsenilin, Cation channel superfamily, Drosophila, Electrophysiology, Guangxitoxin, HERG, Hydrophobe, Ion, Ion channel, KCNA10, KCNA2, KCNA3, KCNA4, KCNA5, KCNA6, KCNA7, KCNAB1, KCNAB2, KCNAB3, KCNB1, KCNB2, KCNC1, KCNC2, KCNC3, KCNC4, KCND1, KCND2, KCND3, KCNE1, KCNE2, KCNE3, KCNE4, KCNE5, KCNF1, KCNG1, KCNG2, KCNG3, KCNG4, KCNH1, KCNH3, KCNH4, KCNH5, KCNH6, KCNH7, KCNH8, KCNIP1, KCNIP2, ..., KCNIP4, KCNQ4, KCNQ5, KCNS1, KCNS2, KCNS3, KCNV1, KCNV2, Kv1.1, KvLQT1, KvLQT2, KvLQT3, Lipid bilayer, Membrane potential, N-terminus, Potassium channel, Potassium channel tetramerisation domain, Shaker gene, Stoichiometry, Voltage-gated ion channel, X-ray crystallography. Expand index (21 more) »

Action potential

In physiology, an action potential occurs when the membrane potential of a specific axon location rapidly rises and falls: this depolarisation then causes adjacent locations to similarly depolarise.

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Alpha helix

The alpha helix (α-helix) is a common motif in the secondary structure of proteins and is a righthand-spiral conformation (i.e. helix) in which every backbone N−H group donates a hydrogen bond to the backbone C.

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Ball and chain inactivation

In neuroscience, ball and chain inactivation is a model to explain the fast inactivation mechanism of voltage-gated ion channels.

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Calsenilin

Calsenilin is a protein that in humans is encoded by the KCNIP3 gene.

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Cation channel superfamily

The transmembrane cation channel superfamily was defined in InterPro and Pfam as the family of tetrameric ion channels.

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Drosophila

Drosophila is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit.

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Electrophysiology

Electrophysiology (from Greek ἥλεκτρον, ēlektron, "amber"; φύσις, physis, "nature, origin"; and -λογία, -logia) is the study of the electrical properties of biological cells and tissues.

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Guangxitoxin

Guangxitoxin, also known as GxTX, is a peptide toxin found in the venom of the tarantula Plesiophrictus guangxiensis.

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HERG

hERG (the human Ether-à-go-go-Related Gene) is a gene that codes for a protein known as Kv11.1, the alpha subunit of a potassium ion channel.

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Hydrophobe

In chemistry, hydrophobicity is the physical property of a molecule (known as a hydrophobe) that is seemingly repelled from a mass of water.

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Ion

An ion is an atom or molecule that has a non-zero net electrical charge (its total number of electrons is not equal to its total number of protons).

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Ion channel

Ion channels are pore-forming membrane proteins that allow ions to pass through the channel pore.

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KCNA10

Potassium voltage-gated channel subfamily A member 10 also known as Kv1.8 is a protein that in humans is encoded by the KCNA10 gene.

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KCNA2

Potassium voltage-gated channel subfamily A member 2 also known as Kv1.2 is a protein that in humans is encoded by the KCNA2 gene.

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KCNA3

Potassium voltage-gated channel, shaker-related subfamily, member 3, also known as KCNA3 or Kv1.3, is a protein that in humans is encoded by the KCNA3 gene.

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KCNA4

Potassium voltage-gated channel subfamily A member 4 also known as Kv1.4 is a protein that in humans is encoded by the KCNA4 gene.

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KCNA5

Potassium voltage-gated channel, shaker-related subfamily, member 5, also known as KCNA5 or Kv1.5, is a protein that in humans is encoded by the KCNA5 gene.

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KCNA6

Potassium voltage-gated channel subfamily A member 6 also known as Kv1.6 is a protein that in humans is encoded by the KCNA6 gene.

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KCNA7

Potassium voltage-gated channel subfamily A member 7 also known as Kv1.7 is a protein that in humans is encoded by the KCNA7 gene.

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KCNAB1

Voltage-gated potassium channel subunit beta-1 is a protein that in humans is encoded by the KCNAB1 gene.

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KCNAB2

Voltage-gated potassium channel subunit beta-2 is a protein that in humans is encoded by the KCNAB2 gene.

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KCNAB3

Voltage-gated potassium channel subunit beta-3 is a protein that in humans is encoded by the KCNAB3 gene.

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KCNB1

Potassium voltage-gated channel, Shab-related subfamily, member 1, also known as KCNB1 or Kv2.1, is a protein that, in humans, is encoded by the KCNB1 gene.

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KCNB2

Potassium voltage-gated channel subfamily B member 2 is a protein that in humans is encoded by the KCNB2 gene.

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KCNC1

Potassium voltage-gated channel subfamily C member 1 is a protein that in humans is encoded by the KCNC1 gene.

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KCNC2

Potassium voltage-gated channel subfamily C member 2 is a protein that in humans is encoded by the KCNC2 gene.

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KCNC3

Potassium voltage-gated channel, Shaw-related subfamily, member 3 also known as KCNC3 or Kv3.3 is a protein that in humans is encoded by the KCNC3.

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KCNC4

Potassium voltage-gated channel, Shaw-related subfamily, member 4 (KCNC4), also known as Kv3.4, is a human gene.

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KCND1

Potassium voltage-gated channel, Shal-related subfamily, member 1 (KCND1), also known as Kv4.1, is a human gene.

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KCND2

Potassium voltage-gated channel subfamily D member 2 is a protein that in humans is encoded by the KCND2 gene.

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KCND3

Potassium voltage-gated channel subfamily D member 3 also known as Kv4.3 is a protein that in humans is encoded by the KCND3 gene.

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KCNE1

Potassium voltage-gated channel subfamily E member 1 is a protein that in humans is encoded by the KCNE1 gene.

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KCNE2

Potassium voltage-gated channel subfamily E member 2 (KCNE2), also known as MinK-related peptide 1 (MiRP1), is a protein that in humans is encoded by the KCNE2 gene on chromosome 21.

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KCNE3

Potassium voltage-gated channel, Isk-related family, member 3 (KCNE3), also known as MinK-related peptide 2 (MiRP2) is a protein that in humans is encoded by the KCNE3 gene.

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KCNE4

Potassium voltage-gated channel subfamily E member 4, originally named MinK-related peptide 3 or MiRP3 when it was discovered, is a protein that in humans is encoded by the KCNE4 gene.

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KCNE5

KCNE1-like also known as KCNE1L is a protein that in humans is encoded by the KCNE1L gene.

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KCNF1

Potassium voltage-gated channel subfamily F member 1 is a protein that in humans is encoded by the KCNF1 gene.

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KCNG1

Potassium voltage-gated channel subfamily G member 1 is a protein that in humans is encoded by the KCNG1 gene.

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KCNG2

Potassium voltage-gated channel subfamily G member 2 is a protein that in humans is encoded by the KCNG2 gene.

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KCNG3

Potassium voltage-gated channel subfamily G member 3 is a protein that in humans is encoded by the KCNG3 gene.

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KCNG4

Potassium voltage-gated channel subfamily G member 4 is a protein that in humans is encoded by the KCNG4 gene.

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KCNH1

Potassium voltage-gated channel subfamily H member 1 is a protein that in humans is encoded by the KCNH1 gene.

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KCNH3

Potassium voltage-gated channel subfamily H member 3 is a protein that in humans is encoded by the KCNH3 gene.

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KCNH4

Potassium voltage-gated channel subfamily H member 4 is a protein that in humans is encoded by the KCNH4 gene.

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KCNH5

Potassium voltage-gated channel, subfamily H (eag-related), member 5, also known as KCNH5, is a human gene encoding the Kv10.2 protein.

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KCNH6

Potassium voltage-gated channel subfamily H member 6 is a protein that in humans is encoded by the KCNH6 gene.

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KCNH7

Potassium voltage-gated channel subfamily H member 7 is a protein that in humans is encoded by the KCNH7 gene.

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KCNH8

Potassium voltage-gated channel subfamily H member 8 is a protein that in humans is encoded by the KCNH8 gene.

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KCNIP1

Kv channel-interacting protein 1 also known as KChIP1 is a protein that in humans is encoded by the KCNIP1 gene.

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KCNIP2

Kv channel-interacting protein 2 also known as KChIP2 is a protein that in humans is encoded by the KCNIP2 gene.

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KCNIP4

Kv channel-interacting protein 4 is a protein that in humans is encoded by the KCNIP4 gene.

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KCNQ4

Potassium voltage-gated channel subfamily KQT member 4 also known as voltage-gated potassium channel subunit Kv7.4 is a protein that in humans is encoded by the KCNQ4 gene.

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KCNQ5

Potassium voltage-gated channel subfamily KQT member 5 is a protein that in humans is encoded by the KCNQ5 gene.

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KCNS1

Potassium voltage-gated channel subfamily S member 1 is a protein that in humans is encoded by the KCNS1 gene.

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KCNS2

Potassium voltage-gated channel subfamily S member 2 is a protein that in humans is encoded by the KCNS2 gene.

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KCNS3

Potassium voltage-gated channel subfamily S member 3 is a protein that in humans is encoded by the KCNS3 gene.

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KCNV1

Potassium voltage-gated channel subfamily V member 1 is a protein that in humans is encoded by the KCNV1 gene.

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KCNV2

Potassium voltage-gated channel subfamily V member 2 is a protein that in humans is encoded by the KCNV2 gene.

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Kv1.1

Potassium voltage-gated channel subfamily A member 1 also known as Kv1.1 is a shaker related voltage-gated potassium channel that in humans is encoded by the KCNA1 gene.

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KvLQT1

Kv7.1 (KvLQT1) is a potassium channel protein whose primary subunit in humans is encoded by the KCNQ1 gene.

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KvLQT2

Kv7.2 (KvLQT2) is a potassium channel protein coded for by the gene KCNQ2.

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KvLQT3

Kv7.3 (KvLQT3) is a potassium channel protein coded for by the gene KCNQ3.

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Lipid bilayer

The lipid bilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid molecules.

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Membrane potential

The term "membrane potential" may refer to one of three kinds of membrane potential.

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N-terminus

The N-terminus (also known as the amino-terminus, NH2-terminus, N-terminal end or amine-terminus) is the start of a protein or polypeptide referring to the free amine group (-NH2) located at the end of a polypeptide.

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Potassium channel

Potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms.

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Potassium channel tetramerisation domain

K+ channel tetramerisation domain is the N-terminal, cytoplasmic tetramerisation domain (T1) of voltage-gated K+ channels.

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Shaker gene

The shaker (Sh) gene, when mutated, causes a variety of atypical behaviors in the fruit fly, Drosophila melanogaster.

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Stoichiometry

Stoichiometry is the calculation of reactants and products in chemical reactions.

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Voltage-gated ion channel

Voltage-gated ion channels are a class of transmembrane proteins that form ion channels that are activated by changes in the electrical membrane potential near the channel.

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X-ray crystallography

X-ray crystallography is a technique used for determining the atomic and molecular structure of a crystal, in which the crystalline atoms cause a beam of incident X-rays to diffract into many specific directions.

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Redirects here:

A-type potassium channel, Delayed rectifier outward potassium current, Potassium channels, voltage-gated, Potassium voltage-gated channel, VGKC, Voltage sensitive calcium channel, Voltage-dependent potassium channel, Voltage-gated K+ channel, Voltage-gated k+ channel, Voltage-gated potassium channels.

References

[1] https://en.wikipedia.org/wiki/Voltage-gated_potassium_channel

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