53 relations: Aneuploidy, Angiogenesis, Apoptosis, Axitinib, Bevacizumab, Blood vessel, Cancer syndrome, CCDC82, Chromosome, CUL2, Cyclin D1, Epithelium, Everolimus, Extracellular matrix, Filamin, Gene, HIF1A, HIF1AN, Hypoxia-inducible factors, Ice hockey, JADE1, Mad2, Mesenchyme, Metastasis, MTOR, Mutation, Neoplasm, Nerve growth factor IB, Pazopanib, Pheochromocytoma, Platelet-derived growth factor, Protein, Protein kinase C, Protein–protein interaction, PSMC3, SAP130, Sirolimus, Sorafenib, Sports league, Sunitinib, TCEB1, TCEB2, Temsirolimus, Transcription factor, Tubulin, Tumor suppressor, Ubiquitin ligase, Unified atomic mass unit, USP33, Vascular endothelial growth factor, ..., Vitamin C, Von Hippel–Lindau binding protein 1, Von Hippel–Lindau disease. Expand index (3 more) »
Aneuploidy
Aneuploidy is the presence of an abnormal number of chromosomes in a cell, for example a human cell having 45 or 47 chromosomes instead of the usual 46.
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Angiogenesis
Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.
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Apoptosis
Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.
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Axitinib
Axitinib (AG013736; trade name Inlyta) is a small molecule tyrosine kinase inhibitor developed by Pfizer.
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Bevacizumab
Bevacizumab, sold under the trade name Avastin, is medication used to treat a number of types of cancers and a specific eye disease.
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Blood vessel
The blood vessels are the part of the circulatory system, and microcirculation, that transports blood throughout the human body.
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Cancer syndrome
A cancer syndrome or family cancer syndrome is a genetic disorder in which inherited genetic mutations in one or more genes predispose the affected individuals to the development of cancers and may also cause the early onset of these cancers.
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CCDC82
Coiled-Coil Domain Containing protein 82 (CCDC82) is a protein that in humans, is encoded for by the gene of the same name, CCDC82.
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Chromosome
A chromosome (from Ancient Greek: χρωμόσωμα, chromosoma, chroma means colour, soma means body) is a DNA molecule with part or all of the genetic material (genome) of an organism.
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CUL2
Cullin-2 is a protein that in humans is encoded by the CUL2 gene.
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Cyclin D1
Cyclin D1 is a protein that in humans is encoded by the CCND1 gene.
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Epithelium
Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.
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Everolimus
No description.
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Extracellular matrix
In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by support cells that provides structural and biochemical support to the surrounding cells.
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Filamin
Filamins are a class of proteins that hold two actin filaments at large angles.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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HIF1A
Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF-1) that is encoded by the HIF1A gene.
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HIF1AN
Hypoxia-inducible factor 1-alpha inhibitor is a protein that in humans is encoded by the HIF1AN gene.
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Hypoxia-inducible factors
Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia.
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Ice hockey
Ice hockey is a contact team sport played on ice, usually in a rink, in which two teams of skaters use their sticks to shoot a vulcanized rubber puck into their opponent's net to score points.
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JADE1
JADE1 is a protein that in humans is encoded by the JADE1 gene.
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Mad2
Mad2 (mitotic arrest deficient 2) is an essential spindle checkpoint protein.
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Mesenchyme
Mesenchyme, in vertebrate embryology, is a type of connective tissue found mostly during the development of the embryo.
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Metastasis
Metastasis is a pathogenic agent's spread from an initial or primary site to a different or secondary site within the host's body; it is typically spoken of as such spread by a cancerous tumor.
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MTOR
The mammalian target of rapamycin (mTOR), also known as the mechanistic target of rapamycin and FK506-binding protein 12-rapamycin-associated protein 1 (FRAP1), is a kinase that in humans is encoded by the MTOR gene.
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Mutation
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.
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Neoplasm
Neoplasia is a type of abnormal and excessive growth of tissue.
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Nerve growth factor IB
The nerve growth factor IB (NGFIB) also known as Nur77 or NR4A1 (nuclear receptor subfamily 4 group A member 1) is a protein that in humans is encoded by the NR4A1 gene.
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Pazopanib
Pazopanib (trade name Votrient) is a potent and selective multi-targeted receptor tyrosine kinase inhibitor that blocks tumour growth and inhibits angiogenesis. It has been approved for renal cell carcinoma and soft tissue sarcoma by numerous regulatory administrations worldwide.
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Pheochromocytoma
Pheochromocytoma (PCC) is a neuroendocrine tumor of the medulla of the adrenal glands (originating in the chromaffin cells), or extra-adrenal chromaffin tissue that failed to involute after birth, that secretes high amounts of catecholamines, mostly norepinephrine, plus epinephrine to a lesser extent.
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Platelet-derived growth factor
Platelet-derived growth factor (PDGF) is one of numerous growth factors that regulate cell growth and division.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein kinase C
Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins, or a member of this family.
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Protein–protein interaction
Protein–protein interactions (PPIs) are the physical contacts of high specificity established between two or more protein molecules as a result of biochemical events steered by electrostatic forces including the hydrophobic effect.
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PSMC3
26S protease regulatory subunit 6A, also known as 26S proteasome AAA-ATPase subunit Rpt5, is an enzyme that in humans is encoded by the PSMC3 gene.
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SAP130
Histone deacetylase complex subunit SAP130 is an enzyme that in humans is encoded by the SAP130 gene.
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Sirolimus
Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and to treat a rare lung disease called lymphangioleiomyomatosis.
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Sorafenib
Sorafenib (co-developed and co-marketed by Bayer and Onyx Pharmaceuticals as Nexavar), is a kinase inhibitor drug approved for the treatment of primary kidney cancer (advanced renal cell carcinoma), advanced primary liver cancer (hepatocellular carcinoma), and radioactive iodine resistant advanced thyroid carcinoma.
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Sports league
A sports league is a group of sports teams that compete against each other in a specific sport.
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Sunitinib
Sunitinib (marketed as Sutent by Pfizer, and previously known as SU11248) is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor that was approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST) on January 26, 2006.
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TCEB1
Transcription elongation factor B polypeptide 1 is a protein that in humans is encoded by the TCEB1 gene.
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TCEB2
Transcription elongation factor B polypeptide 2 is a protein that in humans is encoded by the TCEB2 gene.
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Temsirolimus
Temsirolimus (codenamed CCI-779) is an intravenous drug for the treatment of renal cell carcinoma (RCC), developed by Wyeth Pharmaceuticals and approved by the U.S. Food and Drug Administration (FDA) in late May 2007, and was also approved by the European Medicines Agency (EMEA) on November 2007.
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Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
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Tubulin
Tubulin in molecular biology can refer either to the tubulin protein superfamily of globular proteins, or one of the member proteins of that superfamily.
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Tumor suppressor
A tumor suppressor gene, or antioncogene, is a gene that protects a cell from one step on the path to cancer.
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Ubiquitin ligase
A ubiquitin ligase (also called an E3 ubiquitin ligase) is a protein that recruits an E2 ubiquitin-conjugating enzyme that has been loaded with ubiquitin, recognizes a protein substrate, and assists or directly catalyzes the transfer of ubiquitin from the E2 to the protein substrate.
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Unified atomic mass unit
The unified atomic mass unit or dalton (symbol: u, or Da) is a standard unit of mass that quantifies mass on an atomic or molecular scale (atomic mass).
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USP33
Ubiquitin carboxyl-terminal hydrolase 33 is an enzyme that in humans is encoded by the USP33 gene.
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Vascular endothelial growth factor
Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates the formation of blood vessels.
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Vitamin C
Vitamin C, also known as ascorbic acid and L-ascorbic acid, is a vitamin found in food and used as a dietary supplement.
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Von Hippel–Lindau binding protein 1
Von Hippel–Lindau binding protein 1 (VBP1), also known as "prefoldin 3", is a chaperone protein that binds to von Hippel–Lindau protein and transports it from perinuclear granules to the nucleus or cytoplasm inside the cell.
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Von Hippel–Lindau disease
von Hippel–Lindau disease (VHL), also known as Familial cerebello retinal angiomatosis, is a rare genetic disorder with multisystem involvement.
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Redirects here:
VHL, VHL (gene), Von Hippel-Lindau tumor suppressor, Von Hippel-Lindau tumor suppressor gene, Von hippel-lindau tumor suppressor protein.
References
[1] https://en.wikipedia.org/wiki/Von_Hippel–Lindau_tumor_suppressor