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2β-Propanoyl-3β-(4-tolyl)-tropane

Index 2β-Propanoyl-3β-(4-tolyl)-tropane

2β-Propanoyl-3β-(4-tolyl)-tropane also known as WF-11 or 2-PTT is a cocaine analogue 20 times more potent than cocaine at binding to the dopamine transporter with increased selectivity for the norepinephrine transporters. [1]

7 relations: Cocaine, Downregulation and upregulation, Gene expression, List of cocaine analogues, RTI-32, Structural analog, Tyrosine hydroxylase.

Cocaine

Cocaine, also known as coke, is a strong stimulant mostly used as a recreational drug.

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Downregulation and upregulation

In the biological context of organisms' production of gene products, downregulation is the process by which a cell decreases the quantity of a cellular component, such as RNA or protein, in response to an external stimulus.

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Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.

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List of cocaine analogues

This is a list of cocaine analogues.

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RTI-32

(–)-2β-Carbomethoxy-3β-(4-tolyl)tropane (RTI-4229-32, tolpane) is a phenyltropane-based cocaine analogue that has similar properties in vitro to related drugs such as RTI-31.

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Structural analog

A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component.

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Tyrosine hydroxylase

Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA).

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Redirects here:

2β-propanoyl-3β-(4-tolyl)-tropane, WF-11.

References

[1] https://en.wikipedia.org/wiki/2β-Propanoyl-3β-(4-tolyl)-tropane

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