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Wee1

Index Wee1

Wee1 is a nuclear kinase belonging to the Ser/Thr family of protein kinases in the fission yeast Schizosaccharomyces pombe (S. pombe). [1]

39 relations: Apoptosis, BTRC (gene), Budding, C-terminus, Cdc25, Cell cycle, CHEK1, Cyclin, Cyclin B, Cyclin-dependent kinase 1, DNA repair, Eukaryote, Gamma ray, Gene, Gene dosage, Homology (biology), Kinase, Kruppel-like factors, Maturation promoting factor, Mitosis, Molecular mass, Mutant, Paul Nurse, Phosphorylation, Polo kinase, Polo-like kinase, Pom1, Positive feedback, Protein kinase, Proteolysis, Saccharomyces cerevisiae, SCF complex, Schizosaccharomyces pombe, Scottish English, Serine/threonine-specific protein kinase, Ubiquitin ligase, Ultrasensitivity, Unified atomic mass unit, Wee1-like protein kinase.

Apoptosis

Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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BTRC (gene)

F-box/WD repeat-containing protein 1A (FBXW1A) also known as βTrCP1 or Fbxw1 or hsSlimb or pIkappaBalpha-E3 receptor subunit is a protein that in humans is encoded by the BTRC (beta-transducin repeat containing) gene.

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Budding

Budding is a type of asexual reproduction in which a new organism develops from an outgrowth or bud due to cell division at one particular site.

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C-terminus

The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH).

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Cdc25

Cdc25 is a dual-specificity phosphatase first isolated from the yeast Schizosaccharomyces pombe as a cell cycle defective mutant.

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Cell cycle

The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication of its DNA (DNA replication) to produce two daughter cells.

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CHEK1

Checkpoint kinase 1, commonly referred to as Chk1 is an Serine/threonine-specific protein kinase that in humans, is encoded by the CHEK1 gene.

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Cyclin

Cyclin is a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes.

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Cyclin B

Cyclin B is a member of the cyclin family.

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Cyclin-dependent kinase 1

Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine kinase, and is a key player in cell cycle regulation.

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DNA repair

DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome.

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Eukaryote

Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).

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Gamma ray

A gamma ray or gamma radiation (symbol γ or \gamma), is penetrating electromagnetic radiation arising from the radioactive decay of atomic nuclei.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Gene dosage

Gene dosage is the number of copies of a particular gene present in a genome.

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Homology (biology)

In biology, homology is the existence of shared ancestry between a pair of structures, or genes, in different taxa.

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Kinase

In biochemistry, a kinase is an enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates.

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Kruppel-like factors

In molecular genetics, the Krüppel-like family of transcription factors (KLFs) are a set of zinc finger DNA-binding proteins that regulate gene expression.

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Maturation promoting factor

Maturation-promoting factor (abbreviated MPF, also called mitosis-promoting factor or M-Phase-promoting factor) is the cyclin-Cdk complex that was discovered first in frog eggs.

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Mitosis

In cell biology, mitosis is a part of the cell cycle when replicated chromosomes are separated into two new nuclei.

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Molecular mass

Relative Molecular mass or molecular weight is the mass of a molecule.

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Mutant

In biology and especially genetics, a mutant is an organism or a new genetic character arising or resulting from an instance of mutation, which is an alteration of the DNA sequence of a gene or chromosome of an organism.

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Paul Nurse

Sir Paul Maxime Nurse (born 25 January 1949), is an English geneticist, former President of the Royal Society and Chief Executive and Director of the Francis Crick Institute.

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Phosphorylation

In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.

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Polo kinase

In enzymology, a polo kinase is a kinase enzyme i.e. one that catalyzes the chemical reaction Thus, the two substrates of these enzymes are ATP and protein, whereas their two products are ADP and phosphoprotein.

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Polo-like kinase

Polo-like kinases (Plks) are regulatory serine/threonin kinases of the cell cycle involved in mitotic entry, mitotic exit, spindle formation, cytokinesis, and meiosis.

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Pom1

Pom1 is a polarity protein kinase in fission yeast, Schizosaccharomyces pombe (S. pombe), that localizes to cell ends and regulates cell division.

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Positive feedback

Positive feedback is a process that occurs in a feedback loop in which the effects of a small disturbance on a system include an increase in the magnitude of the perturbation.

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Protein kinase

A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation).

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Proteolysis

Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids.

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Saccharomyces cerevisiae

Saccharomyces cerevisiae is a species of yeast.

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SCF complex

Skp, Cullin, F-box containing complex (or SCF complex) is a multi-protein E3 ubiquitin ligase complex catalyzing the ubiquitination of proteins destined for proteasomal degradation.

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Schizosaccharomyces pombe

Schizosaccharomyces pombe, also called "fission yeast", is a species of yeast used in traditional brewing and as a model organism in molecular and cell biology.

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Scottish English

Scottish English refers to the varieties of English spoken in Scotland.

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Serine/threonine-specific protein kinase

A serine/threonine protein kinase is a kinase enzyme that phosphorylates the OH group of serine or threonine (which have similar sidechains).

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Ubiquitin ligase

A ubiquitin ligase (also called an E3 ubiquitin ligase) is a protein that recruits an E2 ubiquitin-conjugating enzyme that has been loaded with ubiquitin, recognizes a protein substrate, and assists or directly catalyzes the transfer of ubiquitin from the E2 to the protein substrate.

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Ultrasensitivity

In molecular biology, ultrasensitivity describes an output response that is more sensitive to stimulus change than the hyperbolic Michaelis-Menten response.

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Unified atomic mass unit

The unified atomic mass unit or dalton (symbol: u, or Da) is a standard unit of mass that quantifies mass on an atomic or molecular scale (atomic mass).

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Wee1-like protein kinase

WEE1 homolog (S. pombe), also known as WEE1, is a protein which in humans is encoded by the WEE1 gene.

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Redirects here:

WEE1, WEE1 (gene), Wee (cell cycle), Wee (kinase), Wee 1.

References

[1] https://en.wikipedia.org/wiki/Wee1

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