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Wound healing

Index Wound healing

Wound healing is an intricate process in which the skin repairs itself after injury. [1]

188 relations: Actin, Adult stem cell, Aggressive fibromatosis, Angiogenesis, Apoptosis, Basement membrane, Biofilm, Blood, Blood gas tension, Blood vessel, Bone fracture, Brachytherapy, Bradykinin, Burn center, Capillary, Cell (biology), Cell membrane, Cellular differentiation, Chemotaxis, Chronic wound, Circulatory system, Coagulation, Cold compression therapy, Collagen, Collagen gel contraction assay, Collagen, type III, alpha 1, Collagenase, Collective cell migration, Connective tissue, Contact inhibition, Contraction, Cytokine, Cytoskeleton, Dental extraction, Dermal equivalent, Dermis, Desmosome, Diabetes mellitus, Dressing (medical), Drosophila, Dystrophic calcification, Edema, Eicosanoid, Elastin, Endometrium, Endothelium, Epidermal growth factor, Epidermis, Epithelium, Erythema, ..., European Journal of Cell Biology, Extracellular matrix, Fibrin, Fibroblast, Fibroblast growth factor, Fibrocyte, Fibronectin, First aid, Flap (surgery), Gingivectomy, Gingivoplasty, GLUT1, Glycoprotein, Glycosaminoglycan, Graft (surgery), Granulation tissue, Granulocyte, Ground substance, Growth factor, Haematopoiesis, Hair follicle, Hematopoietic stem cell, Hemidesmosome, Hemostasis, Heparan sulfate, Heparan sulfate analogue, Hepatocyte, Hepatocyte growth factor, HIF1A, Histamine, History of wound care, Hyaluronic acid, Hypertrophic scar, Hypoxia (medical), Hypoxia-inducible factors, Immunosuppression, Incisional hernia, Infection, Inflammation, Injury, Integrin, Intermediate filament, Invertebrate, Ionizing radiation, Ischemia, Keloid, Keratinocyte, Keratinocyte growth factor, Kinin, Lactic acid, Langer's lines, Macrophage, Marjolin's ulcer, Mast cell, Matrix metalloproteinase, Medical Hypotheses, Mesenchymal stem cell, Mesenchyme, Metabolic disorder, Metalloproteinase, Minimally invasive procedures, Mitogen, Molecular biology, Monocyte, Myofibroblast, Necrosis, Nitric oxide, Nutrient, Oxygen, Pathogen-associated molecular pattern, Perfusion, Phagocyte, Phagocytosis, Phenotype, Photodynamic therapy, Placebo, Plasmin, Plasminogen activator, Plastic surgery, Platelet, Platelet-derived growth factor, Porosity, Progenitor cell, Prostacyclin, Prostaglandin, Protease, Protein, Proteoglycan, Pseudopodia, Radical (chemistry), Receptor (biochemistry), Regeneration (biology), Regeneration in humans, Regenerative medicine, Respiratory burst, Salamander, Salivary gland, Scaffolding, Scar, Scar free healing, Scarification, Sebaceous gland, Serotonin, Silicone, Smoking, Smooth muscle tissue, Spleen, Stem cell, Stratum basale, Surgery, Sweat gland, Syncytium, T helper cell, TGF alpha, Thromboxane, Thrombus, Tissue (biology), Tissue engineering, Tissue inhibitor of metalloproteinase, Transactivation, Transcription factor, Transforming growth factor beta, Transmembrane protein, Type I collagen, Ultimate tensile strength, Unit of alcohol, Vascular endothelial growth factor, Vasoconstriction, Vasodilation, Venous ulcer, White blood cell, Wound, Wound bed preparation, Wound dehiscence, Wound healing, Wound licking, Wound, ostomy, and continence nursing, Zinc. Expand index (138 more) »


Actin is a family of globular multi-functional proteins that form microfilaments.

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Adult stem cell

Adult stem cells are undifferentiated cells, found throughout the body after development, that multiply by cell division to replenish dying cells and regenerate damaged tissues.

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Aggressive fibromatosis

Aggressive fibromatosis is a rare condition marked by the presence of desmoid tumors.

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Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.

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Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.

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Basement membrane

The basement membrane is a thin, fibrous, extracellular matrix of tissue that separates the lining of an internal or external body surface from underlying connective tissue in metazoans.

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A biofilm comprises any group of microorganisms in which cells stick to each other and often also to a surface.

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Blood is a body fluid in humans and other animals that delivers necessary substances such as nutrients and oxygen to the cells and transports metabolic waste products away from those same cells.

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Blood gas tension

Blood gas tension refers to the partial pressure of gases in blood.

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Blood vessel

The blood vessels are the part of the circulatory system, and microcirculation, that transports blood throughout the human body.

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Bone fracture

A bone fracture (sometimes abbreviated FRX or Fx, Fx, or #) is a medical condition in which there is a partial or complete break in the continuity of the bone.

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Brachytherapy is a form of radiotherapy where a sealed radiation source is placed inside or next to the area requiring treatment.

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Bradykinin is an inflammatory mediator.

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Burn center

A burn center, burn unit or burns unit is a hospital specializing in the treatment of burns.

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A capillary is a small blood vessel from 5 to 10 micrometres (µm) in diameter, and having a wall one endothelial cell thick.

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Cell (biology)

The cell (from Latin cella, meaning "small room") is the basic structural, functional, and biological unit of all known living organisms.

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Cell membrane

The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates the interior of all cells from the outside environment (the extracellular space).

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Cellular differentiation

In developmental biology, cellular differentiation is the process where a cell changes from one cell type to another.

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Chemotaxis (from chemo- + taxis) is the movement of an organism in response to a chemical stimulus.

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Chronic wound

A chronic wound is a wound that does not heal in an orderly set of stages and in a predictable amount of time the way most wounds do; wounds that do not heal within three months are often considered chronic.

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Circulatory system

The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.

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Coagulation (also known as clotting) is the process by which blood changes from a liquid to a gel, forming a blood clot.

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Cold compression therapy

Cold compression therapy, also known as hilotherapy, combines two of the principles of rest, ice, compression, elevation to reduce pain and swelling from a sports or activity injury to soft tissues and recommended by orthopedic surgeons following surgery.

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Collagen is the main structural protein in the extracellular space in the various connective tissues in animal bodies.

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Collagen gel contraction assay

The collagen gel contraction assay is a type of wound contraction.

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Collagen, type III, alpha 1

Collagen alpha-1(III) chain is a protein that in humans is encoded by the COL3A1 gene, which is located on chromosome 2.

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Collagenases are enzymes that break the peptide bonds in collagen.

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Collective cell migration

Collective cell migration describes the movements of group of cells and the emergence of collective behavior from cell-environment interactions and cell-cell communication.

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Connective tissue

Connective tissue (CT) is one of the four basic types of animal tissue, along with epithelial tissue, muscle tissue, and nervous tissue.

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Contact inhibition

In cell biology, contact inhibition refers to two different but closely related phenomena: contact inhibition of locomotion (CIL) and contact inhibition of proliferation (CIP).

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Contraction may refer to.

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Cytokines are a broad and loose category of small proteins (~5–20 kDa) that are important in cell signaling.

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A cytoskeleton is present in all cells of all domains of life (archaea, bacteria, eukaryotes).

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Dental extraction

A dental extraction (also referred to as tooth extraction, exodontia, exodontics, or informally, tooth pulling) is the removal of teeth from the dental alveolus (socket) in the alveolar bone.

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Dermal equivalent

The dermal equivalent is an in vitro model of the dermal layer of skin.

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The dermis or corium is a layer of skin between the epidermis (with which it makes up the cutis) and subcutaneous tissues, that primarily consists of dense irregular connective tissue and cushions the body from stress and strain.

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A desmosome ("binding body"), also known as a macula adhaerens (plural: maculae adhaerentes) (Latin for adhering spot), is a cell structure specialized for cell-to-cell adhesion.

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Diabetes mellitus

Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.

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Dressing (medical)

A dressing is a sterile pad or compress applied to a wound to promote healing and protect the wound from further harm.

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Drosophila is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit.

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Dystrophic calcification

Dystrophic calcification (DC) is the calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules.

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Edema, also spelled oedema or œdema, is an abnormal accumulation of fluid in the interstitium, located beneath the skin and in the cavities of the body, which can cause severe pain.

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Eicosanoids are signaling molecules made by the enzymatic or non-enzymatic oxidation of arachidonic acid or other polyunsaturated fatty acids (PUFAs) that are, similar to arachidonic acid, 20 carbon units in length.

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Elastin is a highly elastic protein in connective tissue and allows many tissues in the body to resume their shape after stretching or contracting.

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The endometrium is the inner epithelial layer, along with its mucous membrane, of the mammalian uterus.

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Endothelium refers to cells that line the interior surface of blood vessels and lymphatic vessels, forming an interface between circulating blood or lymph in the lumen and the rest of the vessel wall.

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Epidermal growth factor

Epidermal growth factor (EGF) stimulates cell growth and differentiation by binding to its receptor, EGFR.

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The epidermis is the outer layer of the three layers that make up the skin, the inner layers being the dermis and hypodermis.

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Epithelium is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue.

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Erythema (from the Greek erythros, meaning red) is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries.

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European Journal of Cell Biology

European Journal of Cell Biology is a monthly peer-reviewed scientific journal that was established in 1969 as Cytobiologie.

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Extracellular matrix

In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by support cells that provides structural and biochemical support to the surrounding cells.

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Fibrin (also called Factor Ia) is a fibrous, non-globular protein involved in the clotting of blood.

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A fibroblast is a type of biological cell that synthesizes the extracellular matrix and collagen, the structural framework (stroma) for animal tissues, and plays a critical role in wound healing.

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Fibroblast growth factor

The fibroblast growth factors are a family of cell signalling proteins that are involved in a wide variety of processes, most notably as crucial elements for normal development.

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A fibrocyte is an inactive mesenchymal cell, that is, a cell showing minimal cytoplasm, limited amounts of rough endoplasmic reticulum and lacks biochemical evidence of protein synthesis.

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Fibronectin is a high-molecular weight (~440kDa) glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins.

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First aid

First aid is the assistance given to any person suffering a sudden illness or injury, with care provided to preserve life, prevent the condition from worsening, or to promote recovery.

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Flap (surgery)

Flap surgery is a technique in plastic and reconstructive surgery where any type of tissue is lifted from a donor site and moved to a recipient site with an intact blood supply.

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Gingivectomy is a dental procedure in which a dentist or oral surgeon cuts away part of the gums in the mouth (the gingiva).

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Gingivoplasty is the process by which the gingiva are reshaped to correct deformities.

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Glucose transporter 1 (or GLUT1), also known as solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), is a uniporter protein that in humans is encoded by the SLC2A1 gene.

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Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to amino acid side-chains.

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Glycosaminoglycans (GAGs) or mucopolysaccharides are long unbranched polysaccharides consisting of a repeating disaccharide unit.

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Graft (surgery)

Grafting refers to a surgical procedure to move tissue from one site to another on the body, or from another creature, without bringing its own blood supply with it.

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Granulation tissue

Granulation tissue is new connective tissue and microscopic blood vessels that form on the surfaces of a wound during the healing process.

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Granulocytes are a category of white blood cells characterized by the presence of granules in their cytoplasm.

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Ground substance

Ground substance is an amorphous gel-like substance in the extracellular space that contains all components of the extracellular matrix except for fibrous materials such as collagen and elastin.

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Growth factor

A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation.

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Haematopoiesis (from Greek αἷμα, "blood" and ποιεῖν "to make"; also hematopoiesis in American English; sometimes also haemopoiesis or hemopoiesis) is the formation of blood cellular components.

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Hair follicle

The hair follicle is a dynamic organ found in mammalian skin.

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Hematopoietic stem cell

Hematopoietic stem cells (HSCs) are the stem cells that give rise to other blood cells.

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Hemidesmosomes (HD) are very small stud-like structures found in keratinocytes of the epidermis of skin that attach to the extracellular matrix (ECM).

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Hemostasis or haemostasis is a process which causes bleeding to stop, meaning to keep blood within a damaged blood vessel (the opposite of hemostasis is hemorrhage).

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Heparan sulfate

Heparan sulfate (HS) is a linear polysaccharide found in all animal tissues.

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Heparan sulfate analogue

Heparan sulfate analogues are polymers engineered to mimic several properties of heparan sulfates.

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A hepatocyte is a cell of the main parenchymal tissue of the liver.

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Hepatocyte growth factor

Hepatocyte growth factor (HGF) (or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells and targets and acts primarily upon epithelial cells and endothelial cells, but also acts on haemopoietic progenitor cells and T cells. It has been shown to have a major role in embryonic organ development, specifically in myogenesis, in adult organ regeneration, and in wound healing.

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Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF-1) that is encoded by the HIF1A gene.

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Histamine is an organic nitrogenous compound involved in local immune responses, as well as regulating physiological function in the gut and acting as a neurotransmitter for the brain, spinal cord, and uterus.

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History of wound care

The history of wound care spans from prehistory to modern medicine.

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Hyaluronic acid

Hyaluronic acid (HA; conjugate base hyaluronate), also called hyaluronan, is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues.

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Hypertrophic scar

A hypertrophic scar is a cutaneous condition characterized by deposits of excessive amounts of collagen which gives rise to a raised scar, but not to the degree observed with keloids.

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Hypoxia (medical)

Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level.

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Hypoxia-inducible factors

Hypoxia-inducible factors (HIFs) are transcription factors that respond to decreases in available oxygen in the cellular environment, or hypoxia.

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Immunosuppression is a reduction of the activation or efficacy of the immune system.

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Incisional hernia

An incisional hernia is a type of hernia caused by an incompletely-healed surgical wound.

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Infection is the invasion of an organism's body tissues by disease-causing agents, their multiplication, and the reaction of host tissues to the infectious agents and the toxins they produce.

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Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Injury, also known as physical trauma, is damage to the body caused by external force.

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Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion.

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Intermediate filament

Intermediate filaments (IFs) are cytoskeletal components found in the cells of vertebrate animal species, and perhaps also in other animals, fungi, plants, and unicellular organisms.

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Invertebrates are animals that neither possess nor develop a vertebral column (commonly known as a backbone or spine), derived from the notochord.

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Ionizing radiation

Ionizing radiation (ionising radiation) is radiation that carries enough energy to liberate electrons from atoms or molecules, thereby ionizing them.

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Ischemia or ischaemia is a restriction in blood supply to tissues, causing a shortage of oxygen that is needed for cellular metabolism (to keep tissue alive).

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Keloid, also known as keloid disorder and keloidal scar, is the formation of a type of scar which, depending on its maturity, is composed mainly of either type III (early) or type I (late) collagen.

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A keratinocyte is the predominant cell type in the epidermis, the outermost layer of the skin, constituting 90% of the cells found there.

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Keratinocyte growth factor

The keratinocyte growth factor (KGF), also known as FGF7, is a growth factor present in the epithelialization-phase of wound healing.

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A kinin is any of various structurally related polypeptides, such as bradykinin and kallidin.

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Lactic acid

Lactic acid is an organic compound with the formula CH3CH(OH)COOH.

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Langer's lines

Langer's lines, Langer lines of skin tension, or sometimes called cleavage lines, are topological lines drawn on a map of the human body.

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Macrophages (big eaters, from Greek μακρός (makrós).

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Marjolin's ulcer

Marjolin's ulcer refers to an aggressive ulcerating squamous cell carcinoma presenting in an area of previously traumatized, chronically inflamed, or scarred skin.

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Mast cell

A mast cell (also known as a mastocyte or a labrocyte) is a type of white blood cell.

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Matrix metalloproteinase

Matrix metalloproteinases (MMPs), also known as matrixins, are calcium-dependent zinc-containing endopeptidases; other family members are adamalysins, serralysins, and astacins.

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Medical Hypotheses

Medical Hypotheses is a medical journal published by Elsevier.

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Mesenchymal stem cell

Mesenchymal stem cells are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells which give rise to marrow adipose tissue).

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Mesenchyme, in vertebrate embryology, is a type of connective tissue found mostly during the development of the embryo.

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Metabolic disorder

A metabolic disorder can happen when abnormal chemical reactions in the body alter the normal metabolic process.

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A metalloproteinase, or metalloprotease, is any protease enzyme whose catalytic mechanism involves a metal.

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Minimally invasive procedures

Minimally invasive procedures (also known as minimally invasive surgeries) encompass surgical techniques that limit the size of incisions needed and so lessen wound healing time, associated pain and risk of infection.

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A mitogen is a chemical substance that encourages a cell to commence cell division, triggering mitosis.

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Molecular biology

Molecular biology is a branch of biology which concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as well as the regulation of these interactions.

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Monocytes are a type of leukocyte, or white blood cell.

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A myofibroblast is a cell that is in between a fibroblast and a smooth muscle cell in phenotype.

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Necrosis (from the Greek νέκρωσις "death, the stage of dying, the act of killing" from νεκρός "dead") is a form of cell injury which results in the premature death of cells in living tissue by autolysis.

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Nitric oxide

Nitric oxide (nitrogen oxide or nitrogen monoxide) is a colorless gas with the formula NO.

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A nutrient is a substance used by an organism to survive, grow, and reproduce.

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Oxygen is a chemical element with symbol O and atomic number 8.

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Pathogen-associated molecular pattern

Pathogen-associated molecular patterns, or PAMPs, are molecules associated with groups of pathogens, that are recognized by cells of the innate immune system.

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Perfusion is the passage of fluid through the circulatory system or lymphatic system to an organ or a tissue, usually referring to the delivery of blood to a capillary bed in tissue.

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Phagocytes are cells that protect the body by ingesting harmful foreign particles, bacteria, and dead or dying cells.

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In cell biology, phagocytosis is the process by which a cell—often a phagocyte or a protist—engulfs a solid particle to form an internal compartment known as a phagosome.

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A phenotype is the composite of an organism's observable characteristics or traits, such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior (such as a bird's nest).

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Photodynamic therapy

Photodynamic therapy (PDT), sometimes called photochemotherapy, is a form of phototherapy involving light and a photosensitizing chemical substance, used in conjunction with molecular oxygen to elicit cell death (phototoxicity).

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A placebo is a substance or treatment of no intended therapeutic value.

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Plasmin is an important enzyme present in blood that degrades many blood plasma proteins, including fibrin clots.

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Plasminogen activator

Plasminogen activators are serine proteases that catalyze the activation of plasmin via proteolytic cleavage of its zymogen form plasminogen.

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Plastic surgery

Plastic surgery is a surgical specialty involving the restoration, reconstruction, or alteration of the human body.

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Platelets, also called thrombocytes (from Greek θρόμβος, "clot" and κύτος, "cell"), are a component of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot.

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Platelet-derived growth factor

Platelet-derived growth factor (PDGF) is one of numerous growth factors that regulate cell growth and division.

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Porosity or void fraction is a measure of the void (i.e. "empty") spaces in a material, and is a fraction of the volume of voids over the total volume, between 0 and 1, or as a percentage between 0% and 100%.

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Progenitor cell

A progenitor cell is a biological cell that, like a stem cell, has a tendency to differentiate into a specific type of cell, but is already more specific than a stem cell and is pushed to differentiate into its "target" cell.

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Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules.

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The prostaglandins (PG) are a group of physiologically active lipid compounds having diverse hormone-like effects in animals.

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A protease (also called a peptidase or proteinase) is an enzyme that performs proteolysis: protein catabolism by hydrolysis of peptide bonds.

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Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.

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Proteoglycans are proteins that are heavily glycosylated.

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A pseudopod or pseudopodium (plural: pseudopods or pseudopodia) (from the Greek word ψευδοποδός, ψευδός "false" + ποδός "foot") is a temporary cytoplasm-filled projection of an eukaryotic cell membrane or a unicellular protist.

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Radical (chemistry)

In chemistry, a radical (more precisely, a free radical) is an atom, molecule, or ion that has an unpaired valence electron.

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Receptor (biochemistry)

In biochemistry and pharmacology, a receptor is a protein molecule that receives chemical signals from outside a cell.

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Regeneration (biology)

In biology, regeneration is the process of renewal, restoration, and growth that makes genomes, cells, organisms, and ecosystems resilient to natural fluctuations or events that cause disturbance or damage.

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Regeneration in humans

Regeneration in humans is the regrowth of lost tissues or organs in response to injury.

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Regenerative medicine

Regenerative medicine is a branch of translational research in tissue engineering and molecular biology which deals with the "process of replacing, engineering or regenerating human cells, tissues or organs to restore or establish normal function".

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Respiratory burst

Respiratory burst (sometimes called oxidative burst) is the rapid release of reactive oxygen species (superoxide radical and hydrogen peroxide) from different types of cells.

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Salamanders are a group of amphibians typically characterized by a lizard-like appearance, with slender bodies, blunt snouts, short limbs projecting at right angles to the body, and the presence of a tail in both larvae and adults.

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Salivary gland

The salivary glands in mammals are exocrine glands that produce saliva through a system of ducts.

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Scaffolding, also called scaffold or staging, is a temporary structure used to support a work crew and materials to aid in the construction, maintenance and repair of buildings, bridges and all other man made structures.

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A scar is an area of fibrous tissue that replaces normal skin after an injury.

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Scar free healing

Scar free healing is the process by which significant injuries can heal without permanent damage to the tissue the injury has affected.

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Scarifying (also scarification modification) involves scratching, etching, burning / branding, or superficially cutting designs, pictures, or words into the skin as a permanent body modification.

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Sebaceous gland

Sebaceous glands are microscopic exocrine glands in the skin that secrete an oily or waxy matter, called sebum, to lubricate and waterproof the skin and hair of mammals.

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Serotonin or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter.

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Silicones, also known as polysiloxanes, are polymers that include any inert, synthetic compound made up of repeating units of siloxane, which is a chain of alternating silicon atoms and oxygen atoms, combined with carbon, hydrogen, and sometimes other elements.

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Smoking is a practice in which a substance is burned and the resulting smoke breathed in to be tasted and absorbed into the bloodstream.

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Smooth muscle tissue

Smooth muscle is an involuntary non-striated muscle.

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The spleen is an organ found in virtually all vertebrates.

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Stem cell

Stem cells are biological cells that can differentiate into other types of cells and can divide to produce more of the same type of stem cells.

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Stratum basale

The stratum basale (basal layer, sometimes referred to as stratum germinativum) is the deepest layer of the five layers of the epidermis, the outer covering of skin in mammals.

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Surgery (from the χειρουργική cheirourgikē (composed of χείρ, "hand", and ἔργον, "work"), via chirurgiae, meaning "hand work") is a medical specialty that uses operative manual and instrumental techniques on a patient to investigate or treat a pathological condition such as a disease or injury, to help improve bodily function or appearance or to repair unwanted ruptured areas.

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Sweat gland

Sweat glands, also known as sudoriferous or sudoriparous glands,, are small tubular structures of the skin that produce sweat.

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A syncytium or symplasm (plural syncytia; from Greek: σύν (syn).

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T helper cell

The T helper cells (Th cells) are a type of T cell that play an important role in the immune system, particularly in the adaptive immune system.

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TGF alpha

Transforming growth factor alpha (TGF-α) is a protein that in humans is encoded by the TGFA gene.

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Thromboxane is a member of the family of lipids known as eicosanoids.

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A thrombus, colloquially called a blood clot, is the final product of the blood coagulation step in hemostasis.

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Tissue (biology)

In biology, tissue is a cellular organizational level between cells and a complete organ.

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Tissue engineering

Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological tissues.

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Tissue inhibitor of metalloproteinase

The matrix metalloproteinases are inhibited by specific endogenous tissue inhibitors of metalloproteinases (TIMPs), which comprise a family of four protease inhibitors: TIMP1, TIMP2, TIMP3 and TIMP4.

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In the context of gene regulation: transactivation is the increased rate of gene expression triggered either by biological processes or by artificial means, through the expression of an intermediate transactivator protein.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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Transforming growth factor beta

Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes four different isoforms (TGF-β 1 to 4, HGNC symbols TGFB1, TGFB2, TGFB3, TGFB4) and many other signaling proteins produced by all white blood cell lineages.

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Transmembrane protein

A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the biological membrane to which it is permanently attached.

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Type I collagen

Type I collagen is the most abundant collagen of the human body which forms large, eosinophilic fibers known as collagen fibers.

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Ultimate tensile strength

Ultimate tensile strength (UTS), often shortened to tensile strength (TS), ultimate strength, or Ftu within equations, is the capacity of a material or structure to withstand loads tending to elongate, as opposed to compressive strength, which withstands loads tending to reduce size.

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Unit of alcohol

Units of alcohol are used in the United Kingdom (UK) as a measure to quantify the actual alcoholic content within a given volume of an alcoholic beverage, in order to provide guidance on total alcohol consumption.

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Vascular endothelial growth factor

Vascular endothelial growth factor (VEGF), originally known as vascular permeability factor (VPF), is a signal protein produced by cells that stimulates the formation of blood vessels.

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Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles.

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Vasodilation is the widening of blood vessels.

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Venous ulcer

Venous ulcers (venous insufficiency ulceration, stasis ulcers, stasis dermatitis, varicose ulcers, or ulcus cruris) are wounds that are thought to occur due to improper functioning of venous valves, usually of the legs (hence leg ulcers).

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White blood cell

White blood cells (WBCs), also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders.

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A wound is a type of injury which happens relatively quickly in which skin is torn, cut, or punctured (an open wound), or where blunt force trauma causes a contusion (a closed wound).

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Wound bed preparation

Wound bed preparation (WBP) is a systematic approach to wound management by identifying and removing barriers to healing.

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Wound dehiscence

Wound dehiscence is a surgical complication in which a wound ruptures along a surgical incision.

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Wound healing

Wound healing is an intricate process in which the skin repairs itself after injury.

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Wound licking

Wound licking is an instinctive response in humans and many other animals to lick an injury.

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Wound, ostomy, and continence nursing

Wound, ostomy and continence nursing is a nursing tri-specialty involved with the treatment of patients with acute and chronic wounds, patients with an ostomy (those who have had some kind of bowel or bladder diversion), and patients with continence conditions (those with bladder and bowel control and associated skin care issues).

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Zinc is a chemical element with symbol Zn and atomic number 30.

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Ephithelialize, Epithelialise, Epithelialization, Fibroplasia phase, Heal wound, Healing of wound, Healing wound, Maturation and remodeling, Maturation and remodeling phase, Natural wound repair, Per primam, Per primam intentionem, Per secundam, Per secundam intentionem, Phases of wound healing, Primary intention, Proliferation phase, Proliferative phase of wound healing, Reepithelialisation, Reepithelialisation phaze, Reepithelialization, Reepithelialization phaze, Scarless wound healing, Second intention, Secondary intention, Tertiary intention, Tissue healing, Vulnerary, Wound healing cascade, Wound healing phases, Wound healing process, Wound repair.


[1] https://en.wikipedia.org/wiki/Wound_healing

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