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XDNA

Index XDNA

xDNA (also known as expanded DNA or benzo-homologated DNA) is a size-expanded nucleotide system synthesized from the fusion of a benzene ring and one of the four natural bases: adenine, guanine, cytosine, and thymine. [1]

74 relations: Absorption (electromagnetic radiation), Active site, Adenine, Adenosine triphosphate, Alkane stereochemistry, Anomer, Aromaticity, Ångström, Base pair, Benzene, Benzothiophene, Biochemistry, Center of mass, Chemical affinity, Chirality (chemistry), Complementary DNA, Cytosine, Diamond Multimedia, DNA, DNA polymerase, DNA polymerase I, DNA polymerase IV, DNA sequencing, DNA-binding protein, Electrical resistivity and conductivity, Electrode, Enzyme, Eric Kool, Excimer, Fluorescence, Fluorophore, Genetic engineering, Glycosidic bond, Guanine, HOMO/LUMO, Hydrocarbon, Hydrogen, Hydrogen bond, Hydrophobe, In situ hybridization, Klenow fragment, Microarray analysis techniques, Molecular wire, Monomer, Nanobiotechnology, Nanoelectronics, Nanoparticle, Naphthalene, Nitrogenous base, Nucleic acid double helix, ..., Nucleic acid sequence, Nucleobase, Nucleotide, Oligomer, Phosphoramidite, Pi interaction, Polyamide, Polymorphism (biology), Purine, Pyrimidine, Quantum yield, Quenching (fluorescence), RNA, Saturation (chemistry), Stokes shift, Substrate (chemistry), Surface area, Terminal deoxynucleotidyl transferase, Thiophene, Thymine, Time-dependent density functional theory, Transcription (biology), Transcription factor, Trellis (architecture). Expand index (24 more) »

Absorption (electromagnetic radiation)

In physics, absorption of electromagnetic radiation is the way in which the energy of a photon is taken up by matter, typically the electrons of an atom.

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Active site

In biology, the active site is the region of an enzyme where substrate molecules bind and undergo a chemical reaction.

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Adenine

Adenine (A, Ade) is a nucleobase (a purine derivative).

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Adenosine triphosphate

Adenosine triphosphate (ATP) is a complex organic chemical that participates in many processes.

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Alkane stereochemistry

Alkane stereochemistry concerns the stereochemistry of alkanes.

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Anomer

An anomer is a type of geometric variation found in at certain atoms in carbohydrate molecules.

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Aromaticity

In organic chemistry, the term aromaticity is used to describe a cyclic (ring-shaped), planar (flat) molecule with a ring of resonance bonds that exhibits more stability than other geometric or connective arrangements with the same set of atoms.

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Ångström

The ångström or angstrom is a unit of length equal to (one ten-billionth of a metre) or 0.1 nanometre.

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Base pair

A base pair (bp) is a unit consisting of two nucleobases bound to each other by hydrogen bonds.

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Benzene

Benzene is an important organic chemical compound with the chemical formula C6H6.

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Benzothiophene

Benzothiophene is an aromatic organic compound with a molecular formula C8H6S and an odor similar to naphthalene (mothballs).

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Biochemistry

Biochemistry, sometimes called biological chemistry, is the study of chemical processes within and relating to living organisms.

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Center of mass

In physics, the center of mass of a distribution of mass in space is the unique point where the weighted relative position of the distributed mass sums to zero, or the point where if a force is applied it moves in the direction of the force without rotating.

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Chemical affinity

In chemical physics and physical chemistry, chemical affinity is the electronic property by which dissimilar chemical species are capable of forming chemical compounds.

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Chirality (chemistry)

Chirality is a geometric property of some molecules and ions.

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Complementary DNA

In genetics, complementary DNA (cDNA) is DNA synthesized from a single stranded RNA (e.g., messenger RNA (mRNA) or microRNA) template in a reaction catalyzed by the enzyme reverse transcriptase.

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Cytosine

Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).

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Diamond Multimedia

Diamond Multimedia is an American company that specializes in many forms of multimedia technology.

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DNA

Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.

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DNA polymerase

DNA polymerases are enzymes that synthesize DNA molecules from deoxyribonucleotides, the building blocks of DNA.

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DNA polymerase I

DNA polymerase I (or Pol I) is an enzyme that participates in the process of prokaryotic DNA replication.

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DNA polymerase IV

DNA polymerase IV is a prokaryotic polymerase that is involved in mutagenesis.

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DNA sequencing

DNA sequencing is the process of determining the precise order of nucleotides within a DNA molecule.

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DNA-binding protein

DNA-binding proteins are proteins that have DNA-binding domains and thus have a specific or general affinity for single- or double-stranded DNA.

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Electrical resistivity and conductivity

Electrical resistivity (also known as resistivity, specific electrical resistance, or volume resistivity) is a fundamental property that quantifies how strongly a given material opposes the flow of electric current.

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Electrode

An electrode is an electrical conductor used to make contact with a nonmetallic part of a circuit (e.g. a semiconductor, an electrolyte, a vacuum or air).

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Enzyme

Enzymes are macromolecular biological catalysts.

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Eric Kool

Eric T. Kool is an American chemist, focusing in chemistry of RNA and DNA; probe design and imaging; synthetic biology, currently the George A. and Hilda M. Daubert Professor in Chemistry at Stanford University and is an Elected Fellow at the American Association for the Advancement of Science.

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Excimer

An excimer (originally short for excited dimer) is a short-lived dimeric or heterodimeric molecule formed from two species, at least one of which has completely filled valence shell by electrons (for example, noble gases).

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Fluorescence

Fluorescence is the emission of light by a substance that has absorbed light or other electromagnetic radiation.

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Fluorophore

A fluorophore (or fluorochrome, similarly to a chromophore) is a fluorescent chemical compound that can re-emit light upon light excitation.

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Genetic engineering

Genetic engineering, also called genetic modification or genetic manipulation, is the direct manipulation of an organism's genes using biotechnology.

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Glycosidic bond

In chemistry, a glycosidic bond or glycosidic linkage is a type of covalent bond that joins a carbohydrate (sugar) molecule to another group, which may or may not be another carbohydrate.

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Guanine

Guanine (or G, Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA).

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HOMO/LUMO

In chemistry, HOMO and LUMO are types of molecular orbitals.

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Hydrocarbon

In organic chemistry, a hydrocarbon is an organic compound consisting entirely of hydrogen and carbon.

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Hydrogen

Hydrogen is a chemical element with symbol H and atomic number 1.

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Hydrogen bond

A hydrogen bond is a partially electrostatic attraction between a hydrogen (H) which is bound to a more electronegative atom such as nitrogen (N), oxygen (O), or fluorine (F), and another adjacent atom bearing a lone pair of electrons.

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Hydrophobe

In chemistry, hydrophobicity is the physical property of a molecule (known as a hydrophobe) that is seemingly repelled from a mass of water.

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In situ hybridization

In situ hybridization (ISH) is a type of hybridization that uses a labeled complementary DNA, RNA or modified nucleic acids strand (i.e., probe) to localize a specific DNA or RNA sequence in a portion or section of tissue (in situ), or, if the tissue is small enough (e.g., plant seeds, Drosophila embryos), in the entire tissue (whole mount ISH), in cells, and in circulating tumor cells (CTCs).

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Klenow fragment

The Klenow fragment is a large protein fragment produced when DNA polymerase I from E. coli is enzymatically cleaved by the protease subtilisin.

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Microarray analysis techniques

Microarray analysis techniques are used in interpreting the data generated from experiments on DNA, RNA, and protein microarrays, which allow researchers to investigate the expression state of a large number of genes - in many cases, an organism's entire genome - in a single experiment.

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Molecular wire

Molecular wires (or sometimes called molecular nanowires) are molecular chains that conduct electric current.

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Monomer

A monomer (mono-, "one" + -mer, "part") is a molecule that "can undergo polymerization thereby contributing constitutional units to the essential structure of a macromolecule".

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Nanobiotechnology

Nanobiotechnology, bionanotechnology, and nanobiology are terms that refer to the intersection of nanotechnology and biology.

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Nanoelectronics

Nanoelectronics refer to the use of nanotechnology in electronic components.

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Nanoparticle

Nanoparticles are particles between 1 and 100 nanometres (nm) in size with a surrounding interfacial layer.

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Naphthalene

Naphthalene is an organic compound with formula.

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Nitrogenous base

A nitrogenous base, or nitrogen-containing base, is an organic molecule with a nitrogen atom that has the chemical properties of a base.

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Nucleic acid double helix

In molecular biology, the term double helix refers to the structure formed by double-stranded molecules of nucleic acids such as DNA.

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Nucleic acid sequence

A nucleic acid sequence is a succession of letters that indicate the order of nucleotides forming alleles within a DNA (using GACT) or RNA (GACU) molecule.

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Nucleobase

Nucleobases, also known as nitrogenous bases or often simply bases, are nitrogen-containing biological compounds that form nucleosides, which in turn are components of nucleotides, with all of these monomers constituting the basic building blocks of nucleic acids.

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Nucleotide

Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth.

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Oligomer

An oligomer (oligo-, "a few" + -mer, "parts") is a molecular complex of chemicals that consists of a few monomer units, in contrast to a polymer, where the number of monomers is, in principle, infinite.

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Phosphoramidite

A phosphoramidite (RO)2PNR2 is a monoamide of a phosphite diester.

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Pi interaction

In chemistry, π-effects or π-interactions are a type of non-covalent interaction that involves π systems.

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Polyamide

A polyamide is a macromolecule with repeating units linked by amide bonds.

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Polymorphism (biology)

Polymorphism in biology and zoology is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species.

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Purine

A purine is a heterocyclic aromatic organic compound that consists of a pyrimidine ring fused to an imidazole ring.

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Pyrimidine

Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine.

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Quantum yield

The quantum yield (Φ) of a radiation-induced process is the number of times a specific event occurs per photon absorbed by the system.

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Quenching (fluorescence)

Quenching refers to any process which decreases the fluorescence intensity of a given substance.

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RNA

Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes.

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Saturation (chemistry)

In chemistry, saturation (from the Latin word saturare, meaning 'to fill') has diverse meanings, all based on the idea of reaching a maximum capacity.

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Stokes shift

Stokes shift is the difference (in wavelength or frequency units) between positions of the band maxima of the absorption and emission spectra (fluorescence and Raman being two examples) of the same electronic transition.

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Substrate (chemistry)

In chemistry, a substrate is typically the chemical species being observed in a chemical reaction, which reacts with a reagent to generate a product.

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Surface area

The surface area of a solid object is a measure of the total area that the surface of the object occupies.

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Terminal deoxynucleotidyl transferase

Terminal deoxynucleotidyl transferase (TdT), also known as DNA nucleotidylexotransferase (DNTT) or terminal transferase, is a specialized DNA polymerase expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells.

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Thiophene

Thiophene is a heterocyclic compound with the formula C4H4S.

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Thymine

---> Thymine (T, Thy) is one of the four nucleobases in the nucleic acid of DNA that are represented by the letters G–C–A–T.

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Time-dependent density functional theory

Time-dependent density functional theory (TDDFT) is a quantum mechanical theory used in physics and chemistry to investigate the properties and dynamics of many-body systems in the presence of time-dependent potentials, such as electric or magnetic fields.

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Transcription (biology)

Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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Trellis (architecture)

A trellis (treillage) is an architectural structure, usually made from an open framework or lattice of interwoven or intersecting pieces of wood, bamboo or metal that is normally made to support and display climbing plants, especially shrubs.

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References

[1] https://en.wikipedia.org/wiki/XDNA

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