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72 relations: Adverse effect, Ankylosing spondylitis, Boxed warning, Brown adipose tissue, Cancer, Carcinogenesis, Cell nucleus, Clinical trial, Combination therapy, Common cold, Contraindication, CYP2C19, CYP3A4, Death, Diarrhea, Disease-modifying antirheumatic drug, Drug development, Drug discovery, Efficacy, Epstein–Barr virus, Etanercept, Fertility, Fluconazole, Food and Drug Administration, Headache, Hemoglobin, Hospital, Immunization, Immunology, Infection, Inflammatory bowel disease, Injury, International nonproprietary name, JAK-STAT signaling pathway, Janus kinase, Janus kinase 1, Janus kinase 3 inhibitor, Janus kinase inhibitor, John O'Shea (biologist), Ketoconazole, Kidney transplantation, Lipid, List of pharmaceutical compound number prefixes, Liver function tests, Lymphocyte, Lymphoma, Lymphoproliferative disorders, Medication, Mutagenesis, National Institute of Arthritis and Musculoskeletal and Skin Diseases, ..., National Institutes of Health, Neutrophil, Obesity, Opportunistic infection, Oral administration, Organ transplantation, Pfizer, Pre-clinical development, Psoriasis, Psoriatic arthritis, Rheumatoid arthritis, Rheumatology, STAT1, Tablet (pharmacy), The New York Times, Transcription (biology), Tuberculosis, Ulcerative colitis, Upper respiratory tract infection, Vaccine, Vitiligo, White adipose tissue. Expand index (22 more) »
Adverse effect
In medicine, an adverse effect is an undesired harmful effect resulting from a medication or other intervention such as surgery.
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Ankylosing spondylitis
Ankylosing spondylitis (AS) is a type of arthritis in which there is long term inflammation of the joints of the spine.
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Boxed warning
In the United States, a boxed warning (sometimes "black box warning", colloquially) is a type of warning that appears on the package insert for certain prescription drugs, so called because the U.S. Food and Drug Administration specifies that it is formatted with a 'box' or border around the text.
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Brown adipose tissue
Brown adipose tissue (BAT) or brown fat makes up the adipose organ together with white adipose tissue (or white fat).
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
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Carcinogenesis
Carcinogenesis, also called oncogenesis or tumorigenesis, is the formation of a cancer, whereby normal cells are transformed into cancer cells.
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Cell nucleus
In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel or seed) is a membrane-enclosed organelle found in eukaryotic cells.
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Clinical trial
Clinical trials are experiments or observations done in clinical research.
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Combination therapy
Combination therapy or polytherapy is therapy that uses more than one medication or modality (versus monotherapy, which is any therapy taken alone).
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Common cold
The common cold, also known simply as a cold, is a viral infectious disease of the upper respiratory tract that primarily affects the nose.
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Contraindication
In medicine, a contraindication is a condition or factor that serves as a reason to withhold a certain medical treatment due to the harm that it would cause the patient.
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CYP2C19
Cytochrome P450 2C19 (abbreviated CYP2C19) is an enzyme.
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CYP3A4
Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.
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Death
Death is the cessation of all biological functions that sustain a living organism.
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Diarrhea
Diarrhea, also spelled diarrhoea, is the condition of having at least three loose or liquid bowel movements each day.
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Disease-modifying antirheumatic drug
Disease-modifying antirheumatic drugs (DMARDs) is a category of otherwise unrelated drugs defined by their use in rheumatoid arthritis to slow down disease progression.
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Drug development
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery.
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Drug discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered.
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Efficacy
Efficacy is the ability to get a job done satisfactorily.
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Epstein–Barr virus
The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is one of eight known human herpesvirus types in the herpes family, and is one of the most common viruses in humans.
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Etanercept
Etanercept (trade name Enbrel) is a biopharmaceutical that treats autoimmune diseases by interfering with tumor necrosis factor (TNF, a soluble inflammatory cytokine) by acting as a TNF inhibitor.
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Fertility
Fertility is the natural capability to produce offspring.
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Fluconazole
Fluconazole is an antifungal medication used for a number of fungal infections.
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Food and Drug Administration
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments.
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Headache
Headache is the symptom of pain anywhere in the region of the head or neck.
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Hemoglobin
Hemoglobin (American) or haemoglobin (British); abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates (with the exception of the fish family Channichthyidae) as well as the tissues of some invertebrates.
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Hospital
A hospital is a health care institution providing patient treatment with specialized medical and nursing staff and medical equipment.
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Immunization
Immunization, or immunisation, is the process by which an individual's immune system becomes fortified against an agent (known as the immunogen).
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Immunology
Immunology is a branch of biology that covers the study of immune systems in all organisms.
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Infection
Infection is the invasion of an organism's body tissues by disease-causing agents, their multiplication, and the reaction of host tissues to the infectious agents and the toxins they produce.
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Inflammatory bowel disease
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine.
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Injury
Injury, also known as physical trauma, is damage to the body caused by external force.
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International nonproprietary name
The International Nonproprietary Name (INN) is an official generic and non-proprietary name given to a pharmaceutical drug or an active ingredient.
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JAK-STAT signaling pathway
The JAK-STAT signalling pathway is a chain of interactions between proteins in a cell, and is involved in processes such as immunity, cell division, cell death and tumour formation.
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Janus kinase
Janus kinase (JAK) is a family of intracellular, nonreceptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway.
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Janus kinase 1
JAK1 is a human tyrosine kinase protein essential for signaling for certain type I and type II cytokines.
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Janus kinase 3 inhibitor
Janus Kinase 3 inhibitors, also called JAK3 inhibitors, are a new class of immunomodulatory agents that inhibit Janus Kinase 3.
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Janus kinase inhibitor
Janus kinase inhibitors, also known as JAK inhibitors or jakinibs, are a type of medication that functions by inhibiting the activity of one or more of the Janus kinase family of enzymes (JAK1, JAK2, JAK3, TYK2), thereby interfering with the JAK-STAT signaling pathway.
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John O'Shea (biologist)
John O'Shea graduated Phi Beta Kappa with a Bachelor of Science degree from St. Lawrence University and a Doctor of Medicine degree from the University of Cincinnati.
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Ketoconazole
Ketoconazole is a synthetic imidazole antifungal drug used primarily to treat fungal infections.
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Kidney transplantation
Kidney transplantation or renal transplantation is the organ transplant of a kidney into a patient with end-stage renal disease.
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Lipid
In biology and biochemistry, a lipid is a biomolecule that is soluble in nonpolar solvents.
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List of pharmaceutical compound number prefixes
This list of pharmaceutical compound number prefixes details a pharmaceutical drug labeling standard.
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Liver function tests
Liver function tests (LFTs or LFs) are groups of blood tests that give information about the state of a patient's liver.
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Lymphocyte
A lymphocyte is one of the subtypes of white blood cell in a vertebrate's immune system.
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Lymphoma
Lymphoma is a group of blood cancers that develop from lymphocytes (a type of white blood cell).
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Lymphoproliferative disorders
Lymphoproliferative disorders (LPDs) refer to several conditions in which lymphocytes are produced in excessive quantities.
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Medication
A medication (also referred to as medicine, pharmaceutical drug, or simply drug) is a drug used to diagnose, cure, treat, or prevent disease.
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Mutagenesis
Mutagenesis is a process by which the genetic information of an organism is changed, resulting in a mutation.
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National Institute of Arthritis and Musculoskeletal and Skin Diseases
The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is one of the institutes and centers that make up the National Institutes of Health, an agency of the United States Department of Health and Human Services (HHS).
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National Institutes of Health
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research, founded in the late 1870s.
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Neutrophil
Neutrophils (also known as neutrocytes) are the most abundant type of granulocytes and the most abundant (40% to 70%) type of white blood cells in most mammals.
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Obesity
Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health.
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Opportunistic infection
An opportunistic infection is an infection caused by pathogens (bacteria, viruses, fungi, or protozoa) that take advantage of an opportunity not normally available, such as a host with a weakened immune system, an altered microbiota (such as a disrupted gut microbiota), or breached integumentary barriers.
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Oral administration
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Organ transplantation
Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ.
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Pfizer
Pfizer Inc. is an American pharmaceutical conglomerate headquartered in New York City, with its research headquarters in Groton, Connecticut.
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Pre-clinical development
In drug development, preclinical development, also named preclinical studies and nonclinical studies, is a stage of research that begins before clinical trials (testing in humans) can begin, and during which important feasibility, iterative testing and drug safety data are collected.
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Psoriasis
Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin.
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Psoriatic arthritis
Psoriatic arthritis is a long-term inflammatory arthritis that occurs in people affected by the autoimmune disease psoriasis.
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Rheumatoid arthritis
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.
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Rheumatology
Rheumatology (Greek ρεύμα, rheuma, flowing current) is a branch of medicine devoted to the diagnosis and therapy of rheumatic diseases.
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STAT1
Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene.
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Tablet (pharmacy)
A tablet is a pharmaceutical dosage form.
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The New York Times
The New York Times (sometimes abbreviated as The NYT or The Times) is an American newspaper based in New York City with worldwide influence and readership.
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Transcription (biology)
Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.
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Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by the bacterium Mycobacterium tuberculosis (MTB).
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Ulcerative colitis
Ulcerative colitis (UC) is a long-term condition that results in inflammation and ulcers of the colon and rectum.
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Upper respiratory tract infection
Upper respiratory tract infections (URTI) are illnesses caused by an acute infection which involves the upper respiratory tract including the nose, sinuses, pharynx or larynx.
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Vaccine
A vaccine is a biological preparation that provides active acquired immunity to a particular disease.
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Vitiligo
Vitiligo is a long-term skin condition characterized by patches of the skin losing their pigment.
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White adipose tissue
White adipose tissue (WAT) or white fat is one of the two types of adipose tissue found in mammals.
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Redirects here:
ATC code L04AA29, ATCvet code QL04AA29, CP-690,550, Tasocitinib, Tofacitinib citrate, Xeljanz.
References
[1] https://en.wikipedia.org/wiki/Tofacitinib
