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Yohimbine

Index Yohimbine

Yohimbine is an indole alkaloid derived from the bark of the Pausinystalia yohimbe tree in Central Africa. [1]

57 relations: Africa, Ajmalicine, Alpha-1 adrenergic receptor, Alpha-1A adrenergic receptor, Alpha-1B adrenergic receptor, Alpha-1D adrenergic receptor, Alpha-2 adrenergic receptor, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, Alpha-2C adrenergic receptor, Biochemical Pharmacology (journal), British Journal of Pharmacology, Corpus cavernosum penis, Corynanthine, Deserpidine, Dietary supplement, Dopamine receptor D2, Dopamine receptor D3, Erectile dysfunction, Eugene van Tamelen, European Food Safety Authority, Exposure therapy, Indole alkaloid, Insomnia, Journal of Organic Chemistry, Journal of the American Chemical Society, Ligand (biochemistry), Mitragynine, Molar concentration, Nervous system, Nitric oxide, Norepinephrine, Oral administration, Partial agonist, Pausinystalia johimbe, Posttraumatic stress disorder, Rauwolscine, Receptor antagonist, Rescinnamine, Reserpine, Serotonin transporter, Smooth muscle tissue, Spegatrine, Tachycardia, Traditional medicine, Vasoconstriction, Vasodilation, Xylazine, 5-HT1A receptor, 5-HT1B receptor, ..., 5-HT1D receptor, 5-HT1E receptor, 5-HT1F receptor, 5-HT2A receptor, 5-HT2B receptor, 5-HT5A receptor, 5-HT7 receptor. Expand index (7 more) »

Africa

Africa is the world's second largest and second most-populous continent (behind Asia in both categories).

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Ajmalicine

Ajmalicine, also known as δ-yohimbine or raubasine, is an antihypertensive drug used in the treatment of high blood pressure.

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Alpha-1 adrenergic receptor

The alpha-1 (α1) adrenergic receptor is a G protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G-protein.

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Alpha-1A adrenergic receptor

The alpha-1A adrenergic receptor (α1A adrenoreceptor), also known as ADRA1A, formerly known also as the alpha-1C adrenergic receptor, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it.

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Alpha-1B adrenergic receptor

The alpha-1B adrenergic receptor (α1B adrenoreceptor), also known as ADRA1B, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it.

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Alpha-1D adrenergic receptor

The alpha-1D adrenergic receptor (α1D adrenoreceptor), also known as ADRA1D, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it.

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Alpha-2 adrenergic receptor

The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein.

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Alpha-2A adrenergic receptor

The alpha-2A adrenergic receptor (α2A adrenoceptor), also known as ADRA2A, is an α2 adrenergic receptor, and also denotes the human gene encoding it.

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Alpha-2B adrenergic receptor

The alpha-2B adrenergic receptor (α2B adrenoceptor), is a G-protein coupled receptor.

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Alpha-2C adrenergic receptor

The alpha-2C adrenergic receptor (α2C adrenoceptor), also known as ADRA2C, is an alpha-2 adrenergic receptor, and also denotes the human gene encoding it.

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Biochemical Pharmacology (journal)

Biochemical Pharmacology is a peer-reviewed medical journal published by Elsevier.

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British Journal of Pharmacology

The British Journal of Pharmacology is a biweekly peer-reviewed medical journal covering all aspects of experimental pharmacology.

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Corpus cavernosum penis

A corpus cavernosum penis (singular) (cavernous body of the penis) is one of a pair of sponge-like regions of erectile tissue, the corpora cavernosa (plural) (cavernous bodies), which contain most of the blood in the penis during an erection.

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Corynanthine

Corynanthine, also known as rauhimbine, is an alkaloid found in the Rauwolfia and Pausinystalia (formerly known as Corynanthe) genera of plants.

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Deserpidine

Deserpidine (INN) is an antihypertensive drug related to reserpine which occurs naturally in Rauvolfia spp.

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Dietary supplement

A dietary supplement is a manufactured product intended to supplement the diet when taken by mouth as a pill, capsule, tablet, or liquid.

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Dopamine receptor D2

Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene.

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Dopamine receptor D3

Dopamine receptor D3 is a protein that in humans is encoded by the DRD3 gene.

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Erectile dysfunction

Erectile dysfunction (ED), also known as impotence, is a type of sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual activity.

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Eugene van Tamelen

Eugene Earle van Tamelen (July 20, 1925 – December 12, 2009) was an organic chemist who is especially recognized for his contributions to bioorganic chemistry.

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European Food Safety Authority

The European Food Safety Authority (EFSA) is the agency of the European Union (EU) that provides independent scientific advice and communicates on existing and emerging risks associated with the food chain.

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Exposure therapy

Exposure therapy is a technique in behavior therapy thought to help treat anxiety disorders.

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Indole alkaloid

Indole alkaloids are a class of alkaloids containing a structural moiety of indole; many indole alkaloids also include isoprene groups and are thus called terpene indole or secologanin tryptamine alkaloids.

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Insomnia

Insomnia, also known as sleeplessness, is a sleep disorder where people have trouble sleeping.

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Journal of Organic Chemistry

The Journal of Organic Chemistry, colloquially known as JOC or J Org, is a peer-reviewed scientific journal for original contributions of fundamental research in all branches of theory and practice in organic and bioorganic chemistry.

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Journal of the American Chemical Society

The Journal of the American Chemical Society (also known as JACS) is a weekly peer-reviewed scientific journal that was established in 1879 by the American Chemical Society.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Mitragynine

Mitragynine is an indole-based opioid-receptor agonist and the most abundant active alkaloid in the plant Mitragyna speciosa, commonly known as kratom and biak-biak.

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Molar concentration

Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular of a solute in a solution, in terms of amount of substance per unit volume of solution.

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Nervous system

The nervous system is the part of an animal that coordinates its actions by transmitting signals to and from different parts of its body.

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Nitric oxide

Nitric oxide (nitrogen oxide or nitrogen monoxide) is a colorless gas with the formula NO.

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Norepinephrine

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter.

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Oral administration

| name.

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Partial agonist

In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.

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Pausinystalia johimbe

Pausinystalia johimbe, (Rubiaceae), common name Yohimbe, is a plant species native to western and central Africa (Nigeria, Cabinda, Cameroon, Congo-Brazzaville, Gabon, Equatorial Guinea).

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Posttraumatic stress disorder

Posttraumatic stress disorder (PTSD)Acceptable variants of this term exist; see the Terminology section in this article.

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Rauwolscine

Rauwolscine, also known as isoyohimbine, α-yohimbine, and corynanthidine, is an alkaloid found in various species within the genera Rauwolfia and Pausinystalia (formerly known as Corynanthe).

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Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

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Rescinnamine

Rescinnamine, known by the brand names moderil, cinnasil, and anaprel, is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug.

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Reserpine

Reserpine (also known by trade names Raudixin, Serpalan, Serpasil) is an indole alkaloid, Major Types Of Chemical Compounds In Plants & Animals Part II: Phenolic Compounds, Glycosides & Alkaloids. Wayne's Word: An On-Line Textbook of Natural History.

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Serotonin transporter

The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene.

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Smooth muscle tissue

Smooth muscle is an involuntary non-striated muscle.

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Spegatrine

Spegatrine is an adrenergic receptor antagonist isolated from Rauvolfia verticillata.

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Tachycardia

Tachycardia, also called tachyarrhythmia, is a heart rate that exceeds the normal resting rate.

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Traditional medicine

Traditional medicine (also known as indigenous or folk medicine) comprises medical aspects of traditional knowledge that developed over generations within various societies before the era of modern medicine.

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Vasoconstriction

Vasoconstriction is the narrowing of the blood vessels resulting from contraction of the muscular wall of the vessels, in particular the large arteries and small arterioles.

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Vasodilation

Vasodilation is the widening of blood vessels.

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Xylazine

Xylazine is an analogue of clonidine and an agonist at the α2 class of adrenergic receptor.

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5-HT1A receptor

The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptor (5-HT receptor) that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

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5-HT1B receptor

5-hydroxytryptamine receptor 1B also known as the 5-HT1B receptor is a protein that in humans is encoded by the HTR1B gene.

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5-HT1D receptor

5-hydroxytryptamine (serotonin) receptor 1D, also known as HTR1D, is a 5-HT receptor, but also denotes the human gene encoding it.

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5-HT1E receptor

5-hydroxytryptamine (serotonin) 1E receptor (5-HT1E) is a highly expressed human G-protein coupled receptor that belongs to the 5-HT1 receptor family (Gi-coupled serotonin receptor).

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5-HT1F receptor

5-hydroxytryptamine (serotonin) receptor 1F, also known as HTR1F is a 5-HT1 receptor protein and also denotes the human gene encoding it.

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5-HT2A receptor

The mammalian 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR).

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5-HT2B receptor

5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the HTR2B gene.

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5-HT5A receptor

5-Hydroxytryptamine (serotonin) receptor 5A, also known as HTR5A, is a protein that in humans is encoded by the HTR5A gene.

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5-HT7 receptor

The 5-HT7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) The 5-HT7 receptor is coupled to Gs (stimulates the production of the intracellular signaling molecule cAMP) and is expressed in a variety of human tissues, particularly in the brain, the gastrointestinal tract, and in various blood vessels.

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Redirects here:

ATC code G04BE04, ATCvet code QG04BE04, ATCvet code QV03AB93, Actibine, Aphrodin, Aphrodyne, Baron-X, Corynine, Dayto himbin, Hydroergotocin, Johimbine, Quebrachin, Thybine, Yobine, Yohimar, Yohimbe tree bark extract, Yohimbic acid, Yohimbin, Yohimbine hydrochloride, Yohimbinum, Yohimex, Yohimvetol, Yoman, Yovital.

References

[1] https://en.wikipedia.org/wiki/Yohimbine

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