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Yohimbine

Index Yohimbine

Yohimbine, also known as quebrachine, is an indole alkaloid derived from the bark of the African tree Pausinystalia johimbe; also from the bark of the unrelated South American tree Aspidosperma quebracho-blanco. [1]

Table of Contents

  1. 91 relations: Africa, Ajmalicine, Alchornea, Alkaloid, Alpha-1 adrenergic receptor, Alpha-1A adrenergic receptor, Alpha-1B adrenergic receptor, Alpha-1D adrenergic receptor, Alpha-2 adrenergic receptor, Alpha-2 blocker, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, Alpha-2C adrenergic receptor, Alstonine, Amsonia, Aphrodisiac, Apocynaceae, Aspidosperma quebracho-blanco, Cameroon, Canopy (biology), Catharanthus, CFA franc, Corpus cavernosum penis, Corynanthe johimbe, Corynanthine, Delayed ejaculation, Deserpidine, Dopamine receptor D2, Dopamine receptor D3, Doping in sport, Energy drink, Erectile dysfunction, Eugene van Tamelen, Euphorbiaceae, Exposure therapy, Food and Drug Administration, Gelsemium, George Barger, Gran Chaco, Hydrochloride, Illegal logging, Indole, Infrared spectroscopy, IUCN Red List, Journal of the American Chemical Society, Libido, Ligand (biochemistry), Locus coeruleus, Loganiaceae, Mass spectrometry, ... Expand index (41 more) »

  2. Alkaloids found in Euphorbiaceae
  3. Alkaloids found in Rauvolfia
  4. Anxiogenics
  5. Indoloquinolizines
  6. Norepinephrine releasing agents
  7. Quinolizidine alkaloids
  8. Sympathomimetics
  9. Vasoconstrictors

Africa

Africa is the world's second-largest and second-most populous continent after Asia.

See Yohimbine and Africa

Ajmalicine

Ajmalicine, also known as δ-yohimbine or raubasine, is an antihypertensive drug used in the treatment of high blood pressure. Yohimbine and Ajmalicine are alkaloids found in Rauvolfia, alpha-1 blockers, Heterocyclic compounds with 5 rings, Indoloquinolizines, Methyl esters, Quinolizidine alkaloids and Tryptamine alkaloids.

See Yohimbine and Ajmalicine

Alchornea

Alchornea is a plant genus of the family Euphorbiaceae first described as a genus in 1788.

See Yohimbine and Alchornea

Alkaloid

Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom.

See Yohimbine and Alkaloid

Alpha-1 adrenergic receptor

alpha-1 (α1) adrenergic receptors are G protein-coupled receptors (GPCRs) associated with the Gq heterotrimeric G protein.

See Yohimbine and Alpha-1 adrenergic receptor

Alpha-1A adrenergic receptor

The alpha-1A adrenergic receptor (α1A adrenoreceptor), also known as ADRA1A, formerly known also as the alpha-1C adrenergic receptor, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it.

See Yohimbine and Alpha-1A adrenergic receptor

Alpha-1B adrenergic receptor

The alpha-1B adrenergic receptor (α1B-adrenoreceptor), also known as ADRA1B, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it.

See Yohimbine and Alpha-1B adrenergic receptor

Alpha-1D adrenergic receptor

The alpha-1D adrenergic receptor (α1D adrenoreceptor), also known as ADRA1D, is an alpha-1 adrenergic receptor, and also denotes the human gene encoding it.

See Yohimbine and Alpha-1D adrenergic receptor

Alpha-2 adrenergic receptor

The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein.

See Yohimbine and Alpha-2 adrenergic receptor

Alpha-2 blocker

Alpha-2 blockers (or α2 blockers) are a subset of the alpha blocker class of drugs and are antagonists to the α2 adrenergic receptor. Yohimbine and alpha-2 blocker are alpha-2 blockers.

See Yohimbine and Alpha-2 blocker

Alpha-2A adrenergic receptor

The alpha-2A adrenergic receptor (α2A adrenoceptor), also known as ADRA2A, is an α2 adrenergic receptor, and also denotes the human gene encoding it.

See Yohimbine and Alpha-2A adrenergic receptor

Alpha-2B adrenergic receptor

The alpha-2B adrenergic receptor (α2B adrenoceptor), is a G-protein coupled receptor.

See Yohimbine and Alpha-2B adrenergic receptor

Alpha-2C adrenergic receptor

The alpha-2C adrenergic receptor (α2C adrenoceptor), also known as ADRA2C, is an alpha-2 adrenergic receptor, and also denotes the human gene encoding it.

See Yohimbine and Alpha-2C adrenergic receptor

Alstonine

Alstonine is a pentacyclic alkaloid and putative antipsychotic constituent of various plant species including Alstonia boonei, Catharanthus roseus, Picralima nitida, Rauwolfia caffra and Rauwolfia vomitoria. Yohimbine and Alstonine are Heterocyclic compounds with 5 rings, Indoloquinolizines and Methyl esters.

See Yohimbine and Alstonine

Amsonia

Amsonia is a genus of flowering plants in the dogbane family, Apocynaceae, first described as a genus in 1788.

See Yohimbine and Amsonia

Aphrodisiac

An aphrodisiac is a substance alleged to increase libido, sexual desire, sexual attraction, sexual pleasure, or sexual behavior.

See Yohimbine and Aphrodisiac

Apocynaceae

Apocynaceae (from Apocynum, Greek for "dog-away") is a family of flowering plants that includes trees, shrubs, herbs, stem succulents, and vines, commonly known as the dogbane family, because some taxa were used as dog poison.

See Yohimbine and Apocynaceae

Aspidosperma quebracho-blanco

Aspidosperma quebracho-blanco, commonly known as Quebracho blanco, kebrako, or white quebracho, is a South American tree species, native to Brazil, northern Argentina, Bolivia, Paraguay, and Uruguay.

See Yohimbine and Aspidosperma quebracho-blanco

Cameroon

Cameroon, officially the Republic of Cameroon, is a country in Central Africa.

See Yohimbine and Cameroon

Canopy (biology)

In biology, the canopy is the aboveground portion of a plant cropping or crop, formed by the collection of individual plant crowns.

See Yohimbine and Canopy (biology)

Catharanthus

Catharanthus is a genus of flowering plants in the family Apocynaceae.

See Yohimbine and Catharanthus

CFA franc

The CFA franc (franc CFA), or Franc of the Financial Community of Africa (originally the Franc of the French Colonies in Africa,; colloquially franc; abbreviation: F.CFA), is the name of two currencies, the West African CFA franc, used in eight West African countries, and the Central African CFA franc, used in six Central African countries.

See Yohimbine and CFA franc

Corpus cavernosum penis

A corpus cavernosum penis (singular) (literally "porous body" of the penis,: corpora cavernosa) is one of a pair of sponge-like regions of erectile tissue, which contain most of the blood in the penis during an erection.

See Yohimbine and Corpus cavernosum penis

Corynanthe johimbe

Corynanthe johimbe, synonym Pausinystalia johimbe, common name yohimbe, is a plant species in the family Rubiaceae native to western and central Africa (Nigeria, Cabinda, Cameroon, Congo-Brazzaville, Gabon, Equatorial Guinea).

See Yohimbine and Corynanthe johimbe

Corynanthine

Corynanthine, also known as rauhimbine, is an alkaloid found in the Rauvolfia and Corynanthe (including Pausinystalia) genera of plants. Yohimbine and Corynanthine are alkaloids found in Rauvolfia, alpha-1 blockers, alpha-2 blockers, Heterocyclic compounds with 5 rings, Indoloquinolizines, Methyl esters, Quinolizidine alkaloids and Tryptamine alkaloids.

See Yohimbine and Corynanthine

Delayed ejaculation

Delayed ejaculation (DE) describes a man's inability or persistent difficulty in achieving orgasm, despite typical sexual desire and sexual stimulation.

See Yohimbine and Delayed ejaculation

Deserpidine

Deserpidine (INN) or reserpidine (USAN) is an antihypertensive drug structurally related to reserpine which occurs naturally in Rauvolfia spp. Yohimbine and Deserpidine are alkaloids found in Rauvolfia, Heterocyclic compounds with 5 rings, Indoloquinolizines, Methyl esters, Quinolizidine alkaloids and Tryptamine alkaloids.

See Yohimbine and Deserpidine

Dopamine receptor D2

Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene.

See Yohimbine and Dopamine receptor D2

Dopamine receptor D3

Dopamine receptor D3 is a protein that in humans is encoded by the DRD3 gene.

See Yohimbine and Dopamine receptor D3

Doping in sport

In competitive sports, doping is the use of banned athletic performance-enhancing drugs (PEDs) by athletic competitors, as a way of cheating.

See Yohimbine and Doping in sport

Energy drink

An energy drink is a type of functional beverage containing stimulant compounds, usually caffeine, which is marketed as providing mental and physical stimulation (marketed as "energy", but distinct from food energy).

See Yohimbine and Energy drink

Erectile dysfunction

Erectile dysfunction (ED), also referred to as impotence, is a form of sexual dysfunction in males characterized by the persistent or recurring inability to achieve or maintain a penile erection with sufficient rigidity and duration for satisfactory sexual activity.

See Yohimbine and Erectile dysfunction

Eugene van Tamelen

Eugene Earle van Tamelen (July 20, 1925 – December 12, 2009) was an organic chemist who is especially recognized for his contributions to bioorganic chemistry.

See Yohimbine and Eugene van Tamelen

Euphorbiaceae

Euphorbiaceae, the spurge family, is a large family of flowering plants.

See Yohimbine and Euphorbiaceae

Exposure therapy

Exposure therapy is a technique in behavior therapy to treat anxiety disorders.

See Yohimbine and Exposure therapy

Food and Drug Administration

The United States Food and Drug Administration (FDA or US FDA) is a federal agency of the Department of Health and Human Services.

See Yohimbine and Food and Drug Administration

Gelsemium

Gelsemium is an Asian and North American genus of flowering plants belonging to family Gelsemiaceae.

See Yohimbine and Gelsemium

George Barger

George Barger FRS FRSE FCS LLD (4 April 1878 – 5 January 1939) was a British chemist.

See Yohimbine and George Barger

Gran Chaco

The Gran Chaco or Dry Chaco is a sparsely populated, hot and semiarid lowland tropical dry broadleaf forest natural region of the Río de la Plata basin, divided among eastern Bolivia, western Paraguay, northern Argentina, and a portion of the Brazilian states of Mato Grosso and Mato Grosso do Sul, where it is connected with the Pantanal region.

See Yohimbine and Gran Chaco

Hydrochloride

In chemistry, a hydrochloride is an acid salt resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (e.g. an amine).

See Yohimbine and Hydrochloride

Illegal logging

Illegal logging is the harvest, transportation, purchase, or sale of timber in violation of laws.

See Yohimbine and Illegal logging

Indole

Indole is an organic compound with the formula.

See Yohimbine and Indole

Infrared spectroscopy

Infrared spectroscopy (IR spectroscopy or vibrational spectroscopy) is the measurement of the interaction of infrared radiation with matter by absorption, emission, or reflection.

See Yohimbine and Infrared spectroscopy

IUCN Red List

The International Union for Conservation of Nature (IUCN) Red List of Threatened Species, also known as the IUCN Red List or Red Data Book, founded in 1964, is an inventory of the global conservation status and extinction risk of biological species.

See Yohimbine and IUCN Red List

Journal of the American Chemical Society

The Journal of the American Chemical Society (also known as JACS) is a weekly peer-reviewed scientific journal that was established in 1879 by the American Chemical Society.

See Yohimbine and Journal of the American Chemical Society

Libido

In psychology, libido (from the Latin, 'desire') is psychic drive or energy, usually conceived as sexual in nature, but sometimes conceived as including other forms of desire.

See Yohimbine and Libido

Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

See Yohimbine and Ligand (biochemistry)

Locus coeruleus

The locus coeruleus (LC), also spelled locus caeruleus or locus ceruleus, is a nucleus in the pons of the brainstem involved with physiological responses to stress and panic.

See Yohimbine and Locus coeruleus

Loganiaceae

The Loganiaceae are a family of flowering plants classified in order Gentianales.

See Yohimbine and Loganiaceae

Mass spectrometry

Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions.

See Yohimbine and Mass spectrometry

Mitragynine

Mitragynine is an indole-based alkaloid and the most abundant active alkaloid in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom. Yohimbine and Mitragynine are Indoloquinolizines, Methyl esters and Tryptamine alkaloids.

See Yohimbine and Mitragynine

Molar concentration

Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular, of a solute in a solution, in terms of amount of substance per unit volume of solution.

See Yohimbine and Molar concentration

National Institutes of Health

The National Institutes of Health, commonly referred to as NIH, is the primary agency of the United States government responsible for biomedical and public health research.

See Yohimbine and National Institutes of Health

Negative feedback

Negative feedback (or balancing feedback) occurs when some function of the output of a system, process, or mechanism is fed back in a manner that tends to reduce the fluctuations in the output, whether caused by changes in the input or by other disturbances.

See Yohimbine and Negative feedback

Nervous system

In biology, the nervous system is the highly complex part of an animal that coordinates its actions and sensory information by transmitting signals to and from different parts of its body.

See Yohimbine and Nervous system

Nitric oxide

Nitric oxide (nitrogen oxide or nitrogen monoxide) is a colorless gas with the formula.

See Yohimbine and Nitric oxide

Norepinephrine

Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic chemical in the catecholamine family that functions in the brain and body as a hormone, neurotransmitter and neuromodulator.

See Yohimbine and Norepinephrine

Nuclear magnetic resonance

Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a strong constant magnetic field are perturbed by a weak oscillating magnetic field (in the near field) and respond by producing an electromagnetic signal with a frequency characteristic of the magnetic field at the nucleus.

See Yohimbine and Nuclear magnetic resonance

Oral administration

| name.

See Yohimbine and Oral administration

Partial agonist

In pharmacology, partial agonists are drugs that bind to and activate a given receptor, but have only partial efficacy at the receptor relative to a full agonist.

See Yohimbine and Partial agonist

PDE5 inhibitor

A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

See Yohimbine and PDE5 inhibitor

Post-traumatic stress disorder

Post-traumatic stress disorder (PTSD) is a mental and behavioral disorder that develops from experiencing a traumatic event, such as sexual assault, warfare, traffic collisions, child abuse, domestic violence, or other threats on a person's life or well-being.

See Yohimbine and Post-traumatic stress disorder

Pre-workout

Pre-workout is a generic term for a range of bodybuilding supplement products used by athletes and weightlifters to enhance athletic performance.

See Yohimbine and Pre-workout

Rauvolfia

Rauvolfia (sometimes spelled Rauwolfia) is a genus of evergreen trees and shrubs, commonly known as devil peppers, in the family Apocynaceae.

See Yohimbine and Rauvolfia

Rauwolscine

Rauwolscine, also known as isoyohimbine, α-yohimbine, and corynanthidine, is an alkaloid found in various species within the genera Rauvolfia and Corynanthe (including Pausinystalia). Yohimbine and Rauwolscine are alkaloids found in Rauvolfia, alpha-2 blockers, Heterocyclic compounds with 5 rings, Indoloquinolizines, Methyl esters, Quinolizidine alkaloids and Tryptamine alkaloids.

See Yohimbine and Rauwolscine

Receptor antagonist

A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist.

See Yohimbine and Receptor antagonist

Rescinnamine

Rescinnamine, known by the brand names Moderil, Cinnasil, and Anaprel, is an angiotensin-converting enzyme inhibitor used as an antihypertensive drug. Yohimbine and Rescinnamine are alkaloids found in Rauvolfia, Heterocyclic compounds with 5 rings, Indoloquinolizines, Methyl esters and Tryptamine alkaloids.

See Yohimbine and Rescinnamine

Reserpine

Reserpine is a drug that is used for the treatment of high blood pressure, usually in combination with a thiazide diuretic or vasodilator. Yohimbine and Reserpine are alkaloids found in Rauvolfia, Heterocyclic compounds with 5 rings, Indoloquinolizines and Tryptamine alkaloids.

See Yohimbine and Reserpine

Scientific evidence

Scientific evidence is evidence that serves to either support or counter a scientific theory or hypothesis, although scientists also use evidence in other ways, such as when applying theories to practical problems.

See Yohimbine and Scientific evidence

Serotonin transporter

The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene.

See Yohimbine and Serotonin transporter

Sildenafil

Sildenafil, sold under the brand name Viagra, among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension.

See Yohimbine and Sildenafil

Smooth muscle

Smooth (soft) muscle is one of the three major types of vertebrate muscle tissue, the other being skeletal and cardiac muscle.

See Yohimbine and Smooth muscle

Spegatrine

Spegatrine is an α1- and α2-adrenergic receptor antagonist isolated from Rauvolfia verticillata. Yohimbine and Spegatrine are alkaloids found in Rauvolfia, alpha-1 blockers, alpha-2 blockers, Heterocyclic compounds with 5 rings, Indoloquinolizines and Tryptamine alkaloids.

See Yohimbine and Spegatrine

Strychnos

Strychnos is a genus of flowering plants, belonging to the family Loganiaceae (sometimes Strychnaceae).

See Yohimbine and Strychnos

Tumescence

Tumescence is the quality or state of being tumescent or swollen.

See Yohimbine and Tumescence

Ultraviolet–visible spectroscopy

Ultraviolet (UV) spectroscopy or ultraviolet–visible (UV–VIS) spectrophotometry refers to absorption spectroscopy or reflectance spectroscopy in part of the ultraviolet and the full, adjacent visible regions of the electromagnetic spectrum.

See Yohimbine and Ultraviolet–visible spectroscopy

Vallesia

Vallesia is a genus of plants in the family Apocynaceae first described as a genus in 1794.

See Yohimbine and Vallesia

Vinca

Vinca (Latin: vincire "to bind, fetter") is a genus of flowering plants in the family Apocynaceae, native to Europe, northwest Africa and southwest Asia.

See Yohimbine and Vinca

Weight loss

Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, by a mean loss of fluid, body fat (adipose tissue), or lean mass (namely bone mineral deposits, muscle, tendon, and other connective tissue).

See Yohimbine and Weight loss

World Anti-Doping Agency

The World Anti-Doping Agency (WADA; Agence mondiale antidopage, AMA) is a foundation initiated by the International Olympic Committee based in Canada to promote, coordinate, and monitor the fight against drugs in sports.

See Yohimbine and World Anti-Doping Agency

Xylazine

Xylazine is a structural analog of clonidine and an alpha-2 adrenergic receptor agonist, sold under many trade names worldwide, most notably the Bayer brand name Rompun, as well as Anased, Sedazine and Chanazine.

See Yohimbine and Xylazine

19-Norandrosterone

19-Norandrosterone, also known as 5α-estran-3α-ol-17-one, is a metabolite of nandrolone (19-nortestosterone) and bolandione (19-norandrostenedione) that is formed by 5α-reductase.

See Yohimbine and 19-Norandrosterone

5-HT1A receptor

The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter.

See Yohimbine and 5-HT1A receptor

5-HT1B receptor

5-hydroxytryptamine receptor 1B also known as the 5-HT1B receptor is a protein that in humans is encoded by the HTR1B gene.

See Yohimbine and 5-HT1B receptor

5-HT1D receptor

5-hydroxytryptamine (serotonin) receptor 1D, also known as HTR1D, is a 5-HT receptor, but also denotes the human gene encoding it.

See Yohimbine and 5-HT1D receptor

5-HT1E receptor

5-hydroxytryptamine (serotonin) 1E receptor (5-HT1E) is a highly expressed human G-protein coupled receptor that belongs to the 5-HT1 receptor family (Gi-coupled serotonin receptor).

See Yohimbine and 5-HT1E receptor

5-HT1F receptor

5-hydroxytryptamine (serotonin) receptor 1F, also known as HTR1F is a 5-HT1 receptor protein and also denotes the human gene encoding it.

See Yohimbine and 5-HT1F receptor

5-HT2A receptor

The 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR).

See Yohimbine and 5-HT2A receptor

5-HT2B receptor

5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the HTR2B gene.

See Yohimbine and 5-HT2B receptor

5-HT5A receptor

5-Hydroxytryptamine (serotonin) receptor 5A, also known as HTR5A, is a protein that in humans is encoded by the HTR5A gene.

See Yohimbine and 5-HT5A receptor

5-HT7 receptor

The 5-HT7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT).

See Yohimbine and 5-HT7 receptor

See also

Alkaloids found in Euphorbiaceae

Alkaloids found in Rauvolfia

Anxiogenics

Indoloquinolizines

Norepinephrine releasing agents

Quinolizidine alkaloids

Sympathomimetics

Vasoconstrictors

References

[1] https://en.wikipedia.org/wiki/Yohimbine

Also known as ATC code G04BE04, ATCvet code QG04BE04, ATCvet code QV03AB93, Actibine, Aphrodin, Aphrodyne, Baron-X, Corynine, Dayto himbin, Hydroergotocin, Johimbine, Quebrachin, Quebrachine, Thybine, Yobine, Yocon (drug), Yohimar, Yohimbe tree bark extract, Yohimbic acid, Yohimbin, Yohimbine hydrochloride, Yohimbinum, Yohimex, Yohimvetol, Yoman, Yovital.

, Mitragynine, Molar concentration, National Institutes of Health, Negative feedback, Nervous system, Nitric oxide, Norepinephrine, Nuclear magnetic resonance, Oral administration, Partial agonist, PDE5 inhibitor, Post-traumatic stress disorder, Pre-workout, Rauvolfia, Rauwolscine, Receptor antagonist, Rescinnamine, Reserpine, Scientific evidence, Serotonin transporter, Sildenafil, Smooth muscle, Spegatrine, Strychnos, Tumescence, Ultraviolet–visible spectroscopy, Vallesia, Vinca, Weight loss, World Anti-Doping Agency, Xylazine, 19-Norandrosterone, 5-HT1A receptor, 5-HT1B receptor, 5-HT1D receptor, 5-HT1E receptor, 5-HT1F receptor, 5-HT2A receptor, 5-HT2B receptor, 5-HT5A receptor, 5-HT7 receptor.