ZK-283197

ZK-283197 (also known as BAY 86-5310 or SH-T04211C) is a selective and orally active ERβ agonist which was under development by Bayer Healthcare AG for the treatment of vasomotor symptoms. ^[1]

8 relations: Agonist, Bayer, Binding selectivity, Clinical trial, Estrogen (medication), Estrogen receptor beta, Hot flash, Oral administration.

Agonist

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.

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Bayer

Bayer AG is a German multinational, pharmaceutical and life sciences company.

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Binding selectivity

Binding selectivity is defined with respect to the binding of ligands to a substrate forming a complex.

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Clinical trial

Clinical trials are experiments or observations done in clinical research.

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Estrogen (medication)

An estrogen is a type of medication which is used most commonly in hormonal birth control and menopausal hormone therapy.

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Estrogen receptor beta (ER-β), also known as NR3A2 (nuclear receptor subfamily 3, group A, member 2), is one of two main types of estrogen receptor, a nuclear receptor which is activated by the sex hormone estrogen.

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Hot flash

Hot flashes (American English) or hot flushes (British English) are a form of flushing due to reduced levels of estradiol.

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Oral administration

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Redirects here:

BAY 86-5310, BAY 865,310, BAY 865310, BAY-86-5310, BAY-865,310, BAY-865310, BAY86-5310, BAY865310, SH T04211C, SH-T04211C, SHT04211C, ZK 283197, ZK283197.

References

[1] https://en.wikipedia.org/wiki/ZK-283197

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