Zinc finger transcription factor

Zinc finger transcription factors or ZF-TFs, are transcription factors composed of a zinc finger-binding domain and any of a variety of transcription-factor effector-domains that exert their modulatory effect in the vicinity of any sequence to which the protein domain binds. ^[1]

10 relations: Adenocarcinoma, Artificial transcription factor, Binding domain, Gene therapy, HER2/neu, Transcription factor, Viral vector, Zinc finger, Zinc finger chimera, Zinc finger nuclease.

Adenocarcinoma

Adenocarcinoma (plural adenocarcinomas or adenocarcinomata) is a type of cancerous tumor that can occur in several parts of the body.

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Artificial transcription factor

An artificial transcription factor (ATF) is an example of a chimeral protein, designed to target and modulate gene transcription.

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Binding domain

A binding domain is a protein domain which binds to a specific atom or molecule, such as calcium or DNA.

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Gene therapy

In the medicine field, gene therapy (also called human gene transfer) is the therapeutic delivery of nucleic acid into a patient's cells as a drug to treat disease.

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HER2/neu

Receptor tyrosine-protein kinase erbB-2, also known as CD340 (cluster of differentiation 340), proto-oncogene Neu, Erbb2 (rodent), or ERBB2 (human), is a protein that in humans is encoded by the ERBB2 gene.

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Transcription factor

In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.

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Viral vector

Viral vectors are tools commonly used by molecular biologists to deliver genetic material into cells.

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Zinc finger

A zinc finger is a small protein structural motif that is characterized by the coordination of one or more zinc ions (Zn2+) in order to stabilize the fold.

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Zinc finger chimera

Zinc finger protein chimera are chimeric proteins composed of a DNA-binding zinc finger protein domain and another domain through which the protein exerts its effect.

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Zinc finger nuclease

Zinc-finger nucleases (ZFNs) are artificial restriction enzymes generated by fusing a zinc finger DNA-binding domain to a DNA-cleavage domain.

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Redirects here:

ZFP-TF, ZFP-TFs, Zfptf, Zinc Finger Transcription Factor, Zinc finger protein transcription factor, Zinc finger protein transcription factors, Zinc finger transcription factors.

References

[1] https://en.wikipedia.org/wiki/Zinc_finger_transcription_factor

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