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93 relations: Addiction, Adenoviridae, Affymetrix, Apoptosis, Arabidopsis thaliana, AspicDB, Behavioral addiction, Biodiversity, Caenorhabditis elegans, Calcitonin, Calcitonin gene-related peptide, Cell migration, Cis-regulatory element, Complementary DNA, Consensus sequence, Coverage (genetics), Cross-link, DNA, DNA (cytosine-5)-methyltransferase 3A, DNA methylation, DNA methyltransferase, DNA microarray, Doublesex, Drosophila melanogaster, DSCAM, Endogeny (biology), Eukaryote, Exitron, Exon, Exon skipping, Exonic splicing enhancer, Exonic splicing silencer, Expressed sequence tag, Fas receptor, FOSB, Gene, Gene expression, Genetic disorder, Genome, Heterogeneous ribonucleoprotein particle, HIV, HIV/AIDS, Human genome, Human Genome Project, Hyaluronidase, Immunoprecipitation, Intrinsically disordered proteins, Intron, Isogenic human disease models, Messenger RNA, ..., MST1R, Mutation, Nematode, Nonsense-mediated decay, Nucleus accumbens, Oncogene, One gene–one enzyme hypothesis, Peptide, Phosphodiester bond, Phosphorylation, Polyadenylation, Polypyrimidine tract, Precursor mRNA, Primary transcript, Promoter (genetics), Protein, Protein isoform, Proteome, Pyrimidine, Reading frame, Reporter gene, Retrovirus, RNA-binding protein, RNA-Seq, SciVee, Serine/arginine-rich splicing factor 1, SnRNP, Spliceosome, SR protein, Stop codon, Thyroid, TIA1, Trans-acting, Transcription (biology), Transcription factor, Transcriptional regulation, Transcriptome instability, Transesterification, Translation (biology), Tumors of the hematopoietic and lymphoid tissues, U2, U2AF2, Zygosity. Expand index (43 more) »
Addiction
Addiction is a brain disorder characterized by compulsive engagement in rewarding stimuli despite adverse consequences.
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Adenoviridae
Adenoviruses (members of the family Adenoviridae) are medium-sized (90–100 nm), nonenveloped (without an outer lipid bilayer) viruses with an icosahedral nucleocapsid containing a double stranded DNA genome.
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Affymetrix
Affymetrix, Inc. was an American company that manufactured DNA microarrays; it was based in Santa Clara, California, United States.
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Apoptosis
Apoptosis (from Ancient Greek ἀπόπτωσις "falling off") is a process of programmed cell death that occurs in multicellular organisms.
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Arabidopsis thaliana
Arabidopsis thaliana, the thale cress, mouse-ear cress or arabidopsis, is a small flowering plant native to Eurasia and Africa.
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AspicDB
ASPicDB is a database of human protein variants generated by alternative splicing, a process by which the exons of the RNA produced by transcription of a gene are reconnected in multiple ways during RNA splicing.
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Behavioral addiction
Behavioral addiction is a form of addiction that involves a compulsion to engage in a rewarding non-drug-related behavior – sometimes called a natural reward – despite any negative consequences to the person's physical, mental, social or financial well-being.
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Biodiversity
Biodiversity, a portmanteau of biological (life) and diversity, generally refers to the variety and variability of life on Earth.
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Caenorhabditis elegans
Caenorhabditis elegans is a free-living (not parasitic), transparent nematode (roundworm), about 1 mm in length, that lives in temperate soil environments.
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Calcitonin
Calcitonin (also known as thyrocalcitonin) is a 32-amino acid linear polypeptide hormone that is produced in humans primarily by the parafollicular cells (also known as C-cells) of the thyroid gland, and in many other animals in the ultimopharyngeal body.
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Calcitonin gene-related peptide
Calcitonin gene-related peptide (CGRP) is a member of the calcitonin family of peptides, which in humans exists in two forms, α-CGRP and β-CGRP.
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Cell migration
Cell migration is a central process in the development and maintenance of multicellular organisms.
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Cis-regulatory element
Cis-regulatory elements (CREs) are regions of non-coding DNA which regulate the transcription of neighboring genes.
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Complementary DNA
In genetics, complementary DNA (cDNA) is DNA synthesized from a single stranded RNA (e.g., messenger RNA (mRNA) or microRNA) template in a reaction catalyzed by the enzyme reverse transcriptase.
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Consensus sequence
In molecular biology and bioinformatics, the consensus sequence (or canonical sequence) is the calculated order of most frequent residues, either nucleotide or amino acid, found at each position in a sequence alignment.
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Coverage (genetics)
Coverage (or depth) in DNA sequencing is the number of unique reads that include a given nucleotide in the reconstructed sequence.
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Cross-link
A cross-link is a bond that links one polymer chain to another.
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DNA
Deoxyribonucleic acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses.
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DNA (cytosine-5)-methyltransferase 3A
DNA (cytosine-5)-methyltransferase 3A is an enzyme that catalyzes the transfer of methyl groups to specific CpG structures in DNA, a process called DNA methylation.
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DNA methylation
DNA methylation is a process by which methyl groups are added to the DNA molecule.
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DNA methyltransferase
In biochemistry, the DNA methyltransferase (DNA MTase) family of enzymes catalyze the transfer of a methyl group to DNA.
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DNA microarray
A DNA microarray (also commonly known as DNA chip or biochip) is a collection of microscopic DNA spots attached to a solid surface.
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Doublesex
Doublesex (dsx) is a gene that is involved in the sex determination system of many insects including the fruit fly Drosophila melanogaster.
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Drosophila melanogaster
Drosophila melanogaster is a species of fly (the taxonomic order Diptera) in the family Drosophilidae.
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DSCAM
DSCAM and Dscam are both abbreviations for Down syndrome cell adhesion molecule.
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Endogeny (biology)
Endogenous substances and processes are those that originate from within an organism, tissue, or cell.
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Eukaryote
Eukaryotes are organisms whose cells have a nucleus enclosed within membranes, unlike Prokaryotes (Bacteria and other Archaea).
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Exitron
Exitrons (exonic introns) are produced through alternative splicing and have characteristics of both introns and exons, but are described as retained introns.
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Exon
An exon is any part of a gene that will encode a part of the final mature RNA produced by that gene after introns have been removed by RNA splicing.
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Exon skipping
In molecular biology, exon skipping is a form of RNA splicing used to cause cells to “skip” over faulty or misaligned sections of genetic code, leading to a truncated but still functional protein despite the genetic mutation.
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Exonic splicing enhancer
In molecular biology, an exonic splicing enhancer (ESE) is a DNA sequence motif consisting of 6 bases within an exon that directs, or enhances, accurate splicing of heterogeneous nuclear RNA (hnRNA) or pre-mRNA into messenger RNA (mRNA).
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Exonic splicing silencer
An exonic splicing silencer (ESS) is a short region (usually 4-18 nucleotides) of an exon and is a cis-regulatory element.
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Expressed sequence tag
In genetics, an expressed sequence tag (EST) is a short sub-sequence of a cDNA sequence.
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Fas receptor
The first apoptosis signal receptor (Fas or FasR), also known as apoptosis antigen 1 (APO-1 or APT), cluster of differentiation 95 (CD95) or tumor necrosis factor receptor superfamily member 6 (TNFRSF6) is a protein that in humans is encoded by the FAS gene.
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FOSB
FBJ murine osteosarcoma viral oncogene homolog B, also known as Finkel-Biskis-Jinkins murine osteosarcoma viral oncogene homolog B, FOSB or FosB, is a protein that, in humans, is encoded by the FOSB gene.
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Gene
In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.
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Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product.
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Genetic disorder
A genetic disorder is a genetic problem caused by one or more abnormalities in the genome.
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Genome
In the fields of molecular biology and genetics, a genome is the genetic material of an organism.
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Heterogeneous ribonucleoprotein particle
Heterogeneous nuclear ribonucleoproteins (hnRNPs) are complexes of RNA and protein present in the cell nucleus during gene transcription and subsequent post-transcriptional modification of the newly synthesized RNA (pre-mRNA).
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HIV
The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS).
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HIV/AIDS
Human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV).
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Human genome
The human genome is the complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria.
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Human Genome Project
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the sequence of nucleotide base pairs that make up human DNA, and of identifying and mapping all of the genes of the human genome from both a physical and a functional standpoint.
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Hyaluronidase
Hyaluronidases are a family of enzymes that catalyse the degradation of hyaluronic acid (HA).
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Immunoprecipitation
Immunoprecipitation (IP) is the technique of precipitating a protein antigen out of solution using an antibody that specifically binds to that particular protein.
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Intrinsically disordered proteins
An intrinsically disordered protein (IDP) is a protein that lacks a fixed or ordered three-dimensional structure.
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Intron
An intron is any nucleotide sequence within a gene that is removed by RNA splicing during maturation of the final RNA product.
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Isogenic human disease models
Isogenic human disease models are a family of cells that are selected or engineered to accurately model the genetics of a specific patient population, in vitro.
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Messenger RNA
Messenger RNA (mRNA) is a large family of RNA molecules that convey genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
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MST1R
Macrophage-stimulating protein receptor is a protein that in humans is encoded by the MST1R gene.
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Mutation
In biology, a mutation is the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements.
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Nematode
The nematodes or roundworms constitute the phylum Nematoda (also called Nemathelminthes).
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Nonsense-mediated decay
Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that exists in all eukaryotes.
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Nucleus accumbens
The nucleus accumbens (NAc or NAcc), also known as the accumbens nucleus, or formerly as the nucleus accumbens septi (Latin for nucleus adjacent to the septum) is a region in the basal forebrain rostral to the preoptic area of the hypothalamus.
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Oncogene
An oncogene is a gene that has the potential to cause cancer.
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One gene–one enzyme hypothesis
The one gene–one enzyme hypothesis is the idea that genes act through the production of enzymes, with each gene responsible for producing a single enzyme that in turn affects a single step in a metabolic pathway.
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Peptide
Peptides (from Gr.: πεπτός, peptós "digested"; derived from πέσσειν, péssein "to digest") are short chains of amino acid monomers linked by peptide (amide) bonds.
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Phosphodiester bond
A phosphodiester bond occurs when exactly two of the hydroxyl groups in phosphoric acid react with hydroxyl groups on other molecules to form two ester bonds.
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Phosphorylation
In chemistry, phosphorylation of a molecule is the attachment of a phosphoryl group.
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Polyadenylation
Polyadenylation is the addition of a poly(A) tail to a messenger RNA.
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Polypyrimidine tract
The polypyrimidine tract is a region of pre-messenger RNA (mRNA) that promotes the assembly of the spliceosome, the protein complex specialized for carrying out RNA splicing during the process of post-transcriptional modification.
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Precursor mRNA
Precursor mRNA (pre-mRNA) is an immature single strand of messenger ribonucleic acid (mRNA).
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Primary transcript
A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs.
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Promoter (genetics)
In genetics, a promoter is a region of DNA that initiates transcription of a particular gene.
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Protein
Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues.
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Protein isoform
A protein isoform, or "protein variant" is a member of a set of highly similar proteins that originate from a single gene or gene family and are the result of genetic differences.
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Proteome
The proteome is the entire set of proteins that is, or can be, expressed by a genome, cell, tissue, or organism at a certain time.
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Pyrimidine
Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine.
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Reading frame
In molecular biology, a reading frame is a way of dividing the sequence of nucleotides in a nucleic acid (DNA or RNA) molecule into a set of consecutive, non-overlapping triplets.
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Reporter gene
In molecular biology, a reporter gene (often simply reporter) is a gene that researchers attach to a regulatory sequence of another gene of interest in bacteria, cell culture, animals or plants.
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Retrovirus
A retrovirus is a single-stranded positive-sense RNA virus with a DNA intermediate and, as an obligate parasite, targets a host cell.
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RNA-binding protein
RNA-binding proteins (often abbreviated as RBPs) are proteins that bind to the double or single stranded RNA in cells and participate in forming ribonucleoprotein complexes.
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RNA-Seq
RNA-Seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), uses next-generation sequencing (NGS) to reveal the presence and quantity of RNA in a biological sample at a given moment.
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SciVee
SciVee was a science video sharing website where researchers could upload, view and share science video clips and connect them to scientific literature, posters and slides from 2007-2015.
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Serine/arginine-rich splicing factor 1
Serine/arginine-rich splicing factor 1 (SRSF1) also known as alternative splicing factor 1 (ASF1), pre-mRNA-splicing factor SF2 (SF2) or ASF1/SF2 is a protein that in humans is encoded by the SFRS1 gene.
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SnRNP
snRNPs (pronounced "snurps"), or small nuclear ribonucleoproteins, are RNA-protein complexes that combine with unmodified pre-mRNA and various other proteins to form a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs.
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Spliceosome
A spliceosome is a large and complex molecular machine found primarily within the splicing speckles of the cell nucleus of eukaryotic cells.
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SR protein
SR proteins are a conserved family of proteins involved in RNA splicing.
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Stop codon
In the genetic code, a stop codon (or termination codon) is a nucleotide triplet within messenger RNA that signals a termination of translation into proteins.
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Thyroid
The thyroid gland, or simply the thyroid, is an endocrine gland in the neck, consisting of two lobes connected by an isthmus.
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TIA1
TIA1 is a 3'UTR mRNA binding protein that can bind the 5'TOP sequence of 5'TOP mRNAs.
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Trans-acting
In the field of molecular biology, trans-acting (trans-regulatory, trans-regulation), in general, means "acting from a different molecule" (i.e., intermolecular).
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Transcription (biology)
Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.
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Transcription factor
In molecular biology, a transcription factor (TF) (or sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence.
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Transcriptional regulation
In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity.
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Transcriptome instability
Transcriptome instability is a genome-wide, pre-mRNA splicing-related characteristic of certain cancers.
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Transesterification
In organic chemistry, transesterfication is the process of exchanging the organic group R″ of an ester with the organic group R′ of an alcohol.
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Translation (biology)
In molecular biology and genetics, translation is the process in which ribosomes in the cytoplasm or ER synthesize proteins after the process of transcription of DNA to RNA in the cell's nucleus.
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Tumors of the hematopoietic and lymphoid tissues
Tumors of the hematopoietic and lymphoid tissues or haematopoietic and lymphoid malignancies are tumors that affect the blood, bone marrow, lymph, and lymphatic system.
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U2
U2 are an Irish rock band from Dublin formed in 1976.
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U2AF2
Splicing factor U2AF 65 kDa subunit is a protein that in humans is encoded by the U2AF2 gene.
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Zygosity
Zygosity is the degree of similarity of the alleles for a trait in an organism.
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Alternate mRNA splicing, Alternate splicing, Alternate transcriptional splice, Alternative splicings, Alternatively spliced, Differential splicing, Splice form, Splice isoform, Splice variant, Splice variant analysis, Splicing alteration, Transcript isoform, Transcript variant, Transcript variants.
References
[1] https://en.wikipedia.org/wiki/Alternative_splicing
