3α-Androstanediol and Anabolic steroid

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Difference between 3α-Androstanediol and Anabolic steroid

3α-Androstanediol vs. Anabolic steroid

3α-Androstanediol (often abbreviated as 3α-diol), also known as 5α-androstane-3α,17β-diol, is an endogenous inhibitory androstane neurosteroid and weak androgen, and a major metabolite of dihydrotestosterone (DHT). Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone.

Allosteric modulator

In biochemistry and pharmacology, an allosteric modulator (allo- from the Greek meaning "other") is a substance which indirectly influences (modulates) the effects of a primary ligand that directly activates or deactivates the function of a target protein.

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Androgen

An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.

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Androstane

Androstane is a C19 steroid with a gonane core.

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Breast cancer

Breast cancer is cancer that develops from breast tissue.

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Dihydrotestosterone

Dihydrotestosterone (DHT), or 5α-dihydrotestosterone (5α-DHT), also known as androstanolone or stanolone, is an endogenous androgen sex steroid and hormone.

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Endogeny (biology)

Endogenous substances and processes are those that originate from within an organism, tissue, or cell.

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Estradiol

Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone.

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Estrogen

Estrogen, or oestrogen, is the primary female sex hormone.

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GABAA receptor

The GABAA receptor (GABAAR) is an ionotropic receptor and ligand-gated ion channel.

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Ligand (biochemistry)

In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.

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Membrane androgen receptor

Membrane androgen receptors (mARs) are a group of G protein-coupled receptors (GPCRs) which bind and are activated by testosterone and/or other androgens.

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Metabolite

A metabolite is the intermediate end product of metabolism.

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Neurosteroid

Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors.

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Prostate cancer

Prostate cancer is the development of cancer in the prostate, a gland in the male reproductive system.

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Testosterone

Testosterone is the primary male sex hormone and an anabolic steroid.

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3β-Androstanediol

3β-Androstanediol, also known as 5α-androstane-3β,17β-diol, and often shortened to 3β-diol, is an endogenous steroid hormone.

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