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Analgesic and Methadone

Shortcuts: Differences, Similarities, Jaccard Similarity Coefficient, References.

Difference between Analgesic and Methadone

Analgesic vs. Methadone

An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain. Methadone, sold under the brand name Dolophine among others, is an opioid used to treat pain and as maintenance therapy or to help with tapering in people with opioid dependence.

Similarities between Analgesic and Methadone

Analgesic and Methadone have 25 things in common (in Unionpedia): Central nervous system, Codeine, Constipation, CYP2B6, CYP2D6, CYP3A4, Dextromethorphan, Fever, Hydromorphone, Hypertension, Intravenous therapy, Itch, Ketamine, Levacetylmethadol, Levomethadone, Morphine, N-Methyl-D-aspartic acid, Nausea, Neuropathic pain, NMDA receptor antagonist, Opioid, Opioid receptor, Pain, Pethidine, Vomiting.

Central nervous system

The central nervous system (CNS) is the part of the nervous system consisting of the brain and spinal cord.

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Codeine

Codeine is an opiate used to treat pain, as a cough medicine, and for diarrhea. It is typically used to treat mild to moderate degrees of pain. Greater benefit may occur when combined with paracetamol (acetaminophen) or a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin or ibuprofen. Evidence does not support its use for acute cough suppression in children or adults. In Europe it is not recommended as a cough medicine in those under twelve years of age. It is generally taken by mouth. It typically starts working after half an hour with maximum effect at two hours. The total duration of its effects last for about four to six hours. Common side effects include vomiting, constipation, itchiness, lightheadedness, and drowsiness. Serious side effects may include breathing difficulties and addiction. It is unclear if its use in pregnancy is safe. Care should be used during breastfeeding as it may result in opiate toxicity in the baby. Its use as of 2016 is not recommended in children. Codeine works following being broken down by the liver into morphine. How quickly this occurs depends on a person's genetics. Codeine was discovered in 1832 by Pierre Jean Robiquet. In 2013 about 361,000 kilograms of codeine were produced while 249,000 kilograms were used. This makes it the most commonly taken opiate. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is between 0.04 and 0.29 USD per dose as of 2014. In the United States it costs about one dollar a dose. Codeine occurs naturally and makes up about 2% of opium.

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Constipation

Constipation refers to bowel movements that are infrequent or hard to pass.

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CYP2B6

Cytochrome P450 2B6 is an enzyme that in humans is encoded by the CYP2B6 gene.

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CYP2D6

Cytochrome P450 2D6 (CYP2D6) is an enzyme that in humans is encoded by the CYP2D6 gene.

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CYP3A4

Cytochrome P450 3A4 (abbreviated CYP3A4) is an important enzyme in the body, mainly found in the liver and in the intestine.

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Dextromethorphan

Dextromethorphan (DXM or DM) is a drug of the morphinan class with sedative, dissociative, and stimulant properties (at higher doses).

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Fever

Fever, also known as pyrexia and febrile response, is defined as having a temperature above the normal range due to an increase in the body's temperature set-point.

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Hydromorphone

Hydromorphone, also known as dihydromorphinone, and sold under the brand name Dilaudid, among others, is a centrally acting pain medication of the opioid class.

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Hypertension

Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.

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Intravenous therapy

Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).

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Itch

Itch (also known as pruritus) is a sensation that causes the desire or reflex to scratch.

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Ketamine

Ketamine, sold under the brand name Ketalar among others, is a medication mainly used for starting and maintaining anesthesia.

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Levacetylmethadol

Levacetylmethadol (INN), levomethadyl acetate (USAN), OrLAAM (trade name) or levo-α-acetylmethadol (LAAM) is a synthetic opioid similar in structure to methadone.

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Levomethadone

Levomethadone (INN; L-Polamidon, L-Polamivet, Levadone, Levothyl), or levamethadone, is a synthetic opioid analgesic and antitussive which is marketed in Europe and is used for pain management and in opioid maintenance therapy.

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Morphine

Morphine is a pain medication of the opiate variety which is found naturally in a number of plants and animals.

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N-Methyl-D-aspartic acid

N-Methyl-D-aspartic acid or N-Methyl-D-aspartate (NMDA) is an amino acid derivative that acts as a specific agonist at the NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.

Analgesic and N-Methyl-D-aspartic acid · Methadone and N-Methyl-D-aspartic acid · See more »

Nausea

Nausea or queasiness is an unpleasant sense of unease, discomfort, and revulsion towards food.

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Neuropathic pain

Neuropathic pain is pain caused by damage or disease affecting the somatosensory nervous system.

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NMDA receptor antagonist

NMDA receptor antagonists are a class of anesthetics that work to antagonize, or inhibit the action of, the ''N''-Methyl-D-aspartate receptor (NMDAR).

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Opioid

Opioids are substances that act on opioid receptors to produce morphine-like effects.

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Opioid receptor

Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands.

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Pain

Pain is a distressing feeling often caused by intense or damaging stimuli.

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Pethidine

Pethidine, also known as meperidine and sold under the brand name Demerol among others, is a synthetic opioid pain medication of the phenylpiperidine class.

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Vomiting

Vomiting, also known as emesis, puking, barfing, throwing up, among other terms, is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose.

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The list above answers the following questions

Analgesic and Methadone Comparison

Analgesic has 283 relations, while Methadone has 159. As they have in common 25, the Jaccard index is 5.66% = 25 / (283 + 159).

References

This article shows the relationship between Analgesic and Methadone. To access each article from which the information was extracted, please visit:

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