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CYP2C9

Index CYP2C9

Cytochrome P450 2C9 (abbreviated CYP2C9) is an enzyme that in humans is encoded by the CYP2C9 gene. [1]

148 relations: Acenocoumarol, Acute respiratory distress syndrome, Adverse drug reaction, Alkene, AM-2201, Amentoflavone, Amiodarone, Amitriptyline, Analgesic, Angiogenesis, Angiotensin II receptor blocker, Anti-diabetic medication, Anti-inflammatory, Antiarrhythmic agent, Antibiotic, Anticoagulant, Anticonvulsant, Antifungal, Antihistamine, Antileukotriene, Antipyretic, Apigenin, Aprepitant, Arachidonic acid, Area under the curve (pharmacokinetics), Bactericide, Barbiturate, Bosentan, Cannabidiol, Cannabinol, Celecoxib, Chemotherapy, Chloramphenicol, Clearance (pharmacology), Competitive inhibition, Coronaric acid, Cyclizine, CYP2C19, CYP2C9*13, CYP2C9*3, CYP2J2, CYP2S1, CYP4A11, CYP4F2, Cytochrome P450, Diabetic nephropathy, Diclofenac, Docosahexaenoic acid, Eicosapentaenoic acid, Enzyme, ..., Enzyme induction and inhibition, Epoxide, Epoxydocosapentaenoic acid, Epoxyeicosatetraenoic acid, Epoxyeicosatrienoic acid, Epoxygenase, Erectile dysfunction, Fenofibrate, Fibrate, Flavones, Flavonols, Fluconazole, Fluoxetine, Fluvastatin, Fluvoxamine, Formulary (pharmacy), Gene, Ginkgo biloba, Glibenclamide, Glimepiride, Glipizide, H1 antagonist, Heart failure, Hypericum perforatum, Hypertension, Ibuprofen, Indiana University School of Medicine, Inflammation, Irbesartan, Isoniazid, JWH-018, Ketoprofen, Limonene, Linoleic acid, Loop diuretic, Lornoxicam, Losartan, Lovastatin, Medroxyprogesterone acetate, Meloxicam, Miconazole, Modafinil, Monoterpene, Montelukast, Mood stabilizer, Multiple organ dysfunction syndrome, Myocardial infarction, Naproxen, Nateglinide, Neurohormone, Nifedipine, Non-competitive inhibition, Nonsteroidal anti-inflammatory drug, Omega-3 fatty acid, Phenethyl isothiocyanate, Phenobarbital, Phenylbutazone, Phenytoin, Piroxicam, Polymorphism (biology), Polyunsaturated fat, Polyunsaturated fatty acid, Potency (pharmacology), Probenecid, Promethazine, Quercetin, Rifampicin, Rosiglitazone, Secobarbital, Selective estrogen receptor modulator, Selective serotonin reuptake inhibitor, Sertraline, Sildenafil, Single-nucleotide polymorphism, Statin, Stereoisomerism, Substrate (chemistry), Sulfamethoxazole, Sulfaphenazole, Sulfonylurea, Suprofen, Tamoxifen, Tapentadol, Teniposide, Terbinafine, Tetrahydrocannabinol, Tolbutamide, Torasemide, Tricyclic antidepressant, Tuberculosis, Uricosuric, Valproate, Vernolic acid, Voriconazole, Warfarin, Zafirlukast, 20-Hydroxyeicosatetraenoic acid, 6-Hydroxyflavone. Expand index (98 more) »

Acenocoumarol

Acenocoumarol is an anticoagulant that functions as a vitamin K antagonist (like warfarin).

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Acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) is a medical condition occurring in critically ill or critically wounded patients characterized by widespread inflammation in the lungs.

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Adverse drug reaction

An adverse drug reaction (ADR) is an injury caused by taking a medication.

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Alkene

In organic chemistry, an alkene is an unsaturated hydrocarbon that contains at least one carbon–carbon double bond.

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AM-2201

AM-2201 (1-(5-fluoropentyl)-3-(1-naphthoyl)indole) is a recreational designer drug that acts as a potent but nonselective full agonist for the cannabinoid receptor.

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Amentoflavone

Amentoflavone is a biflavonoid (bis-apigenin coupled at 8 and 3' positions, or 3′,8′′-biapigenin) constituent of a number of plants including Ginkgo biloba, Chamaecyparis obtusa (hinoki), Hypericum perforatum (St. John’s Wort) and Xerophyta plicata.

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Amiodarone

Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of irregular heartbeats.

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Amitriptyline

Amitriptyline, sold under the brand name Elavil among others, is a medicine primarily used to treat a number of mental illnesses.

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Analgesic

An analgesic or painkiller is any member of the group of drugs used to achieve analgesia, relief from pain.

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Angiogenesis

Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels.

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Angiotensin II receptor blocker

Angiotensin II receptor blockers (ARBs), also known as angiotensin II receptor antagonists, AT1 receptor antagonists or sartans, are a group of pharmaceuticals that modulate the renin–angiotensin system.

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Anti-diabetic medication

Drugs used in diabetes treat diabetes mellitus by lowering glucose levels in the blood.

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Anti-inflammatory

Anti-inflammatory, or antiinflammatory, refers to the property of a substance or treatment that reduces inflammation or swelling.

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Antiarrhythmic agent

Antiarrhythmic agents, also known as cardiac dysrhythmia medications, are a group of pharmaceuticals that are used to suppress abnormal rhythms of the heart (cardiac arrhythmias), such as atrial fibrillation, atrial flutter, ventricular tachycardia, and ventricular fibrillation.

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Antibiotic

An antibiotic (from ancient Greek αντιβιοτικά, antibiotiká), also called an antibacterial, is a type of antimicrobial drug used in the treatment and prevention of bacterial infections.

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Anticoagulant

Anticoagulants, commonly referred to as blood thinners, are chemical substances that prevent or reduce coagulation of blood, prolonging the clotting time.

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Anticonvulsant

Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures.

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Antifungal

An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cryptococcal meningitis, and others.

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Antihistamine

Antihistamines are drugs which treat allergic rhinitis and other allergies.

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Antileukotriene

An antileukotriene is a drug which functions as a leukotriene-related enzyme inhibitor (arachidonate 5-lipoxygenase) or leukotriene receptor antagonist (cysteinyl leukotriene receptors) and consequently opposes the function of these inflammatory mediators; leukotrienes are produced by the immune system and serve to promote bronchoconstriction, inflammation, microvascular permeability, and mucus secretion in asthma and COPD.

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Antipyretic

Antipyretics (from anti- 'against' and 'feverish') are substances that reduce fever.

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Apigenin

Apigenin (4′,5,7-trihydroxyflavone), found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally occurring glycosides.

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Aprepitant

Aprepitant (brand name: Emend (the brand name used in all English-speaking countries)) is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists (SPA).

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Arachidonic acid

Arachidonic acid (AA, sometimes ARA) is a polyunsaturated omega-6 fatty acid 20:4(ω-6).

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Area under the curve (pharmacokinetics)

In the field of pharmacokinetics, the area under the curve (AUC) is the definite integral in a plot of drug concentration in blood plasma vs.

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Bactericide

A bactericide or bacteriocide, sometimes abbreviated Bcidal, is a substance that kills bacteria.

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Barbiturate

A barbiturate is a drug that acts as a central nervous system depressant, and can therefore produce a wide spectrum of effects, from mild sedation to death.

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Bosentan

Bosentan is a dual endothelin receptor antagonist used in the treatment of pulmonary artery hypertension (PAH).

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Cannabidiol

Cannabidiol (CBD) is a naturally occurring cannabinoid constituent of cannabis.

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Cannabinol

Cannabinol (CBN) is a non-psychoactive cannabinoid found only in trace amounts in Cannabis, and is mostly found in aged Cannabis. Pharmacologically relevant quantities are formed as a metabolite of tetrahydrocannabinol (THC).

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Celecoxib

Celecoxib, sold under the brand name Celebrex among others, is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID).

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Chemotherapy

Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen.

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Chloramphenicol

Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections.

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Clearance (pharmacology)

In pharmacology, the clearance is a pharmacokinetic measurement of the volume of plasma from which a substance is completely removed per unit time; the usual units are mL/min.

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Competitive inhibition

Competitive inhibition is a form of enzyme inhibition where binding of an inhibitor prevents binding of the target molecule of the enzyme, also known as the substrate.

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Coronaric acid

Coronaric acid (isoleukotoxin) is a mono-unsaturated, epoxide derivative of the di-saturated fatty acid, linoleic acid (i.e. 9(Z),12(Z) octadecadienoic acid. It is a mixture of the two optically active isomers of 12(Z) 9,10-epoxy-octadecenoic acid. This mixture is also termed 9,10-epoxy-12Z-octadecenoic acid or 9(10)-EpOME and when formed by or studied in mammalians, isoleukotoxin.

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Cyclizine

Cyclizine, sold under a number of brand names, is a medication used to treat and prevent nausea, vomiting and dizziness due to motion sickness or vertigo.

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CYP2C19

Cytochrome P450 2C19 (abbreviated CYP2C19) is an enzyme.

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CYP2C9*13

Cytochrome P450 2C9 (CYP2C9), a member of the CYP2C enzyme subfamily, ranks amongst the most important drug metabolizing enzymes in humans.

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CYP2C9*3

Cytochrome P450 2C9 (CYP2C9), a member of the CYP2C enzyme subfamily, ranks amongst the most important drug metabolizing enzymes in humans.

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CYP2J2

Cytochrome P450 2J2 (CYP2J2) is a protein that in humans is encoded by the CYP2J2 gene.

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CYP2S1

Cytochrome P450 2S1 is a protein that in humans is encoded by the CYP2S1 gene.

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CYP4A11

Cytochrome P450 4A11 is a protein that in humans is encoded by the CYP4A11 gene.

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CYP4F2

Leukotriene-B(4) omega-hydroxylase 1 is an enzyme that in humans is encoded by the CYP4F2 gene.

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Cytochrome P450

Cytochromes P450 (CYPs) are proteins of the superfamily containing heme as a cofactor and, therefore, are hemoproteins.

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Diabetic nephropathy

Diabetic nephropathy (DN), also known as diabetic kidney disease, is the chronic loss of kidney function occurring in those with diabetes mellitus.

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Diclofenac

Diclofenac (sold under a number of trade names) is a nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing pain in certain conditions.

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Docosahexaenoic acid

Docosahexaenoic acid (DHA) is an omega-3 fatty acid that is a primary structural component of the human brain, cerebral cortex, skin, and retina.

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Eicosapentaenoic acid

Eicosapentaenoic acid (EPA; also icosapentaenoic acid) is an omega-3 fatty acid.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Enzyme induction and inhibition

Enzyme induction is a process in which a molecule (e.g. a drug) induces (i.e. initiates or enhances) the expression of an enzyme.

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Epoxide

An epoxide is a cyclic ether with a three-atom ring.

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Epoxydocosapentaenoic acid

Epoxide docosapentaenoic acids (epoxydocosapentaenoic acids, EDPs, or EpDPEs) are metabolites of the 22-carbon straight-chain omega-3 fatty acid, docosahexaenoic acid (DHA).

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Epoxyeicosatetraenoic acid

Epoxyeicosatetraenoic acids (EEQs or EpETEs) are a set of biologically active epoxides that various cell types make by metabolizing the omega 3 fatty acid, eicosapentaenoic acid (EPA), with certain cytochrome P450 epoxygenases.

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Epoxyeicosatrienoic acid

The epoxyeicosatrienoic acids or EETs are signaling molecules formed within various types of cells by the metabolism of arachidonic acid by a specific subset of Cytochrome P450 enzymes termed cytochrome P450 epoxygenases.

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Epoxygenase

Epoxygenases are a set of membrane-bound, heme-containing cytochrome P450 (CYP P450 or just CYP) enzymes that metabolize polyunsaturated fatty acids to epoxide products that have a range of biological activities.

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Erectile dysfunction

Erectile dysfunction (ED), also known as impotence, is a type of sexual dysfunction characterized by the inability to develop or maintain an erection of the penis during sexual activity.

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Fenofibrate

Fenofibrate, marketed as Tricor and under several other brand names, is a drug of the fibrate class.

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Fibrate

In pharmacology, the fibrates are a class of amphipathic carboxylic acids.

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Flavones

Flavones (flavus.

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Flavonols

Flavonols are a class of flavonoids that have the 3-hydroxyflavone backbone (IUPAC name: 3-hydroxy-2-phenylchromen-4-one).

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Fluconazole

Fluconazole is an antifungal medication used for a number of fungal infections.

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Fluoxetine

Fluoxetine, also known by trade names Prozac and Sarafem, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

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Fluvastatin

Fluvastatin (INN, trade names Lescol, Canef, Vastin) is a member of the statin drug class, used to treat hypercholesterolemia and to prevent cardiovascular disease.

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Fluvoxamine

Fluvoxamine, sold under the brand name Luvox among others, is a medication which is used primarily for the treatment of obsessive–compulsive disorder (OCD), and is also used to treat major depressive disorder and anxiety disorders such as panic disorder and post-traumatic stress disorder.

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Formulary (pharmacy)

At its most basic level, a formulary is a list of medicines.

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Gene

In biology, a gene is a sequence of DNA or RNA that codes for a molecule that has a function.

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Ginkgo biloba

Ginkgo biloba, commonly known as ginkgo or gingko (both pronounced), also known as the maidenhair tree, is the only living species in the division Ginkgophyta, all others being extinct.

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Glibenclamide

Glibenclamide, also known as glyburide, is an antidiabetic drug in a class of medications known as sulfonylureas, closely related to sulfonamide antibiotics.

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Glimepiride

Glimepiride (original trade name Amaryl) is an orally available medium-to-long-acting sulfonylurea antidiabetic drug.

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Glipizide

Glipizide is an oral rapid- and short-acting anti-diabetic medication from the sulfonylurea class.

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H1 antagonist

H1 antagonists, also called H1 blockers, are a class of medications that block the action of histamine at the H1 receptor, helping to relieve allergic reactions.

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Heart failure

Heart failure (HF), often referred to as congestive heart failure (CHF), is when the heart is unable to pump sufficiently to maintain blood flow to meet the body's needs.

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Hypericum perforatum

Hypericum perforatum, known as perforate St John's-wort, common Saint John's wort and St John's wort, is a flowering plant in the family Hypericaceae.

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Hypertension

Hypertension (HTN or HT), also known as high blood pressure (HBP), is a long-term medical condition in which the blood pressure in the arteries is persistently elevated.

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Ibuprofen

Ibuprofen is a medication in the nonsteroidal anti-inflammatory drug (NSAID) class that is used for treating pain, fever, and inflammation.

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Indiana University School of Medicine

The Indiana University School of Medicine is a medical school and medical research center connected to Indiana University; its principal research and medical center is on the Indiana University – Purdue University Indianapolis campus in Indianapolis.

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Irbesartan

Irbesartan (INN) is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.

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Isoniazid

Isoniazid, also known as isonicotinylhydrazide (INH), is an antibiotic used for the treatment of tuberculosis.

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JWH-018

JWH-018 (1-pentyl-3-(1-naphthoyl)indole) or AM-678 is an analgesic chemical from the naphthoylindole family that acts as a full agonist at both the CB1 and CB2 cannabinoid receptors, with some selectivity for CB2.

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Ketoprofen

Ketoprofen, (RS)-2-(3-benzoylphenyl)-propionic acid (chemical formula C16H14O3) is one of the propionic acid class of nonsteroidal anti-inflammatory drugs (NSAID) with analgesic and antipyretic effects.

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Limonene

Limonene is a clear, colorless liquid hydrocarbon classified as a cyclic monoterpene, and is the major component in the oil of citrus fruit peels.

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Linoleic acid

Linoleic acid (LA), a carboxylic acid, is a polyunsaturated omega-6 fatty acid, an 18-carbon chain with two double bonds in cis configuration.

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Loop diuretic

Loop diuretics are diuretics that act at the ascending limb of the loop of Henle in the kidney.

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Lornoxicam

Lornoxicam (INN, or chlortenoxicam; trade name Xefo, among others) is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic (pain relieving), anti-inflammatory and antipyretic (fever reducing) properties.

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Losartan

Losartan, sold under the trade name Cozaar among others, is a medication mainly used to treat high blood pressure.

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Lovastatin

Lovastatin (Merck's Mevacor) is a statin drug, used for lowering cholesterol in those with hypercholesterolemia to reduce risk of cardiovascular disease.

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Medroxyprogesterone acetate

Medroxyprogesterone acetate (MPA), sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type.

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Meloxicam

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-pyretic effects.

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Miconazole

Miconazole, sold under the brand name Monistat among others, is an antifungal medication used to treat ring worm, pityriasis versicolor, and yeast infections of the skin or vagina.

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Modafinil

Modafinil, sold under the brand name Provigil among others, is a medication to treat sleepiness due to narcolepsy, shift work sleep disorder, or obstructive sleep apnea (OSA). In OSA continuous positive airway pressure is the preferred treatment. While it has seen off-label use as a purported cognitive enhancer, evidence for any benefit is lacking. It is taken by mouth. Common side effects include headache, anxiety, trouble sleeping, and nausea. Serious side effects may include allergic reactions such as anaphylaxis, Stevens–Johnson syndrome, abuse, or hallucinations. It is unclear if use during pregnancy is safe. The amount of medication used may need to be adjusted in those with kidney or liver problems. It is not recommended in those with an arrhythmia, significant hypertension, or left ventricular hypertrophy. How it works is not entirely clear. One possibility is that it may affect the areas of the brain involved with the sleep cycle. Modafinil was approved for medical use in the United States in 1998. In the United States it is classified as a schedule IV controlled substance due to concerns about addiction. In the United Kingdom it is a prescription only medication. It is avaliable as a generic medication. In the United Kingdom it costs the NHS about £105.21 a month as of 2018. In the United States the wholesale cost per month is about 34.20 USD as of 2018.

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Monoterpene

Monoterpenes are a class of terpenes that consist of two isoprene units and have the molecular formula C10H16.

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Montelukast

Montelukast (trade name Singulair) is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.

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Mood stabilizer

A mood stabilizer is a psychiatric pharmaceutical drug used to treat mood disorders characterized by intense and sustained mood shifts, typically bipolar disorder type I or type II, borderline personality disorder (BPD) and schizophrenia.

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Multiple organ dysfunction syndrome

Multiple organ dysfunction syndrome (MODS), also known as multiple organ failure (MOF), total organ failure (TOF) or multisystem organ failure (MSOF), is altered organ function in an acutely ill patient requiring medical intervention to achieve homeostasis.

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Myocardial infarction

Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decreases or stops to a part of the heart, causing damage to the heart muscle.

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Naproxen

Naproxen (brand names: Aleve, Naprosyn, and many others) is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness.

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Nateglinide

Nateglinide (INN, trade name Starlix) is a drug for the treatment of type 2 diabetes.

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Neurohormone

A neurohormone is any hormone produced and released by neuroendocrine cells (also called neurosecretory cells) into the blood.

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Nifedipine

Nifedipine, sold under the brand names Adalat among others, is a medication used to manage angina, high blood pressure, Raynaud's phenomenon, and premature labor.

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Non-competitive inhibition

Non-competitive inhibition is a type of enzyme inhibition where the inhibitor reduces the activity of the enzyme and binds equally well to the enzyme whether or not it has already bound the substrate.

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Nonsteroidal anti-inflammatory drug

Nonsteroidal anti-inflammatory drugs (NSAIDs) are a drug class that reduce pain, decrease fever, prevent blood clots and, in higher doses, decrease inflammation.

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Omega-3 fatty acid

Omega−3 fatty acids, also called ω−3 fatty acids or n−3 fatty acids, are polyunsaturated fatty acids (PUFAs).

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Phenethyl isothiocyanate

Phenethyl isothiocyanate (PEITC) is a naturally occurring isothiocyanate whose precursor, gluconasturtiin is found in some cruciferous vegetables, especially watercress.

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Phenobarbital

Phenobarbital, also known as phenobarbitone or phenobarb, is a medication recommended by the World Health Organization for the treatment of certain types of epilepsy in developing countries.

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Phenylbutazone

Phenylbutazone, often referred to as "bute," is a nonsteroidal anti-inflammatory drug (NSAID) for the short-term treatment of pain and fever in animals.

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Phenytoin

Phenytoin (PHT), sold under the brand name Dilantin among others, is an anti-seizure medication.

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Piroxicam

Piroxicam (INN, BAN, USAN, AAN; in some countries it is spelled piroksikam or piroxikam) is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class used to relieve the symptoms of painful, inflammatory conditions like arthritis.

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Polymorphism (biology)

Polymorphism in biology and zoology is the occurrence of two or more clearly different morphs or forms, also referred to as alternative phenotypes, in the population of a species.

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Polyunsaturated fat

Polyunsaturated fats are fats in which the constituent hydrocarbon chain possesses two or more carbon–carbon double bonds.

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Polyunsaturated fatty acid

Polyunsaturated fatty acids (PUFAs) are fatty acids that contain more than one double bond in their backbone.

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Potency (pharmacology)

In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.

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Probenecid

Probenecid, also sold under the brandname Probalan, is a medication that increases uric acid excretion in the urine.

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Promethazine

Promethazine is a neuroleptic medication and first-generation antihistamine of the phenothiazine family.

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Quercetin

Quercetin, a plant flavonol from the flavonoid group of polyphenols, is found in many fruits, vegetables, leaves, and grains; red onions and kale are common foods containing appreciable content of quercetin.

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Rifampicin

Rifampicin, also known as rifampin, is an antibiotic used to treat several types of bacterial infections, including tuberculosis, leprosy, and Legionnaire's disease.

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Rosiglitazone

Rosiglitazone (trade name Avandia) is an antidiabetic drug in the thiazolidinedione class.

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Secobarbital

Secobarbital sodium (marketed by Eli Lilly and Company, and subsequently by other companies as described below, under the brand name Seconal) is a barbiturate derivative drug that was patented in 1934 in the United States.

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Selective estrogen receptor modulator

Selective estrogen receptor modulators (SERMs) are a class of drugs that act on the estrogen receptor (ER).

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Selective serotonin reuptake inhibitor

Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder and anxiety disorders.

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Sertraline

Sertraline, sold under the trade names Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

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Sildenafil

Sildenafil, sold as the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension.

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Single-nucleotide polymorphism

A single-nucleotide polymorphism, often abbreviated to SNP (plural), is a variation in a single nucleotide that occurs at a specific position in the genome, where each variation is present to some appreciable degree within a population (e.g. > 1%).

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Statin

Statins, also known as HMG-CoA reductase inhibitors, are a class of lipid-lowering medications.

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Stereoisomerism

In stereochemistry, stereoisomers are isomeric molecules that have the same molecular formula and sequence of bonded atoms (constitution), but differ in the three-dimensional orientations of their atoms in space.

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Substrate (chemistry)

In chemistry, a substrate is typically the chemical species being observed in a chemical reaction, which reacts with a reagent to generate a product.

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Sulfamethoxazole

Sulfamethoxazole (SMZ or SMX) is an antibiotic.

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Sulfaphenazole

Sulfaphenazole (or sulfafenazol) is a sulfonamide antibacterial.

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Sulfonylurea

Sulfonylureas (UK: sulphonylurea) are a class of organic compounds used in medicine and agriculture.

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Suprofen

Suprofen is a nonsteroidal anti-inflammatory drug (NSAID) developed by Janssen Pharmaceutica that was marketed as 1% eye drops under the trade name Profenal.

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Tamoxifen

Tamoxifen (TMX), sold under the brand name Nolvadex among others, is a medication that is used to prevent breast cancer in women and treat breast cancer in women and men.

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Tapentadol

Tapentadol (brand names: Nucynta, Palexia and Tapal) is a centrally acting opioid analgesic of the benzenoid class with a dual mode of action as an agonist of the μ-opioid receptor and as a norepinephrine reuptake inhibitor (NRI).

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Teniposide

Teniposide (trade name Vumon) is a chemotherapeutic medication used in the treatment of childhood acute lymphocytic leukemia (ALL), Hodgkin's lymphoma, certain brain tumours, and other types of cancer.

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Terbinafine

Terbinafine, sold under the brand name Lamisil among others, is an antifungal medication used to treat ringworm, pityriasis versicolor, and fungal nail infections.

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Tetrahydrocannabinol

Tetrahydrocannabinol (THC) is one of at least 113 cannabinoids identified in cannabis.

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Tolbutamide

Tolbutamide is a first-generation potassium channel blocker, sulfonylurea oral hypoglycemic medication.

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Torasemide

Torasemide or torsemide is a pyridine-sulfonyl urea type loop diuretic mainly used in the management of edema associated with congestive heart failure.

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Tricyclic antidepressant

Tricyclic antidepressants (TCAs) are a class of medications that are used primarily as antidepressants.

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Tuberculosis

Tuberculosis (TB) is an infectious disease usually caused by the bacterium Mycobacterium tuberculosis (MTB).

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Uricosuric

Uricosuric medications (drugs) are substances that increase the excretion of uric acid in the urine, thus reducing the concentration of uric acid in blood plasma.

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Valproate

Valproate (VPA), and its valproic acid, sodium valproate, and valproate semisodium forms, are medications primarily used to treat epilepsy and bipolar disorder and to prevent migraine headaches.

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Vernolic acid

Vernolic acid (leukotoxin) is a long chain fatty acid that is monounsaturated and contains an epoxide.

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Voriconazole

Voriconazole, sold under the brand name Vfend among others, is an antifungal medication used to treat a number of fungal infections.

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Warfarin

Warfarin, sold under the brand name Coumadin among others, is a medication that is used as an anticoagulant (blood thinner).

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Zafirlukast

Zafirlukast is an orally administered leukotriene receptor antagonist (LTRA) used for the chronic treatment of asthma.

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20-Hydroxyeicosatetraenoic acid

20-Hydroxyeicosatetraenoic acid, also known as 20-HETE or 20-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid, is an eicosanoid metabolite of arachidonic acid that has a wide range of effects on the vascular system including the regulation of vascular tone, blood flow to specific organs, sodium and fluid transport in the kidney, and vascular pathway remodeling.

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6-Hydroxyflavone

6-Hydroxyflavone is a flavone, a type of chemical compound.

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Redirects here:

CPC9, CYP 2C9, CYP2C10, CYP2C11, CYP2C12, CYP2C9 (gene), Cpc9, Cyp2c10, Cytochrome P450 2C9, Cytochrome p-450 cyp2c9, P450 MP-4, P450 PB-1, P450 mp-4, P450 pb-1, P450IIC9, P450iic9.

References

[1] https://en.wikipedia.org/wiki/CYP2C9

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