Similarities between CYP3A4 and Spironolactone
CYP3A4 and Spironolactone have 29 things in common (in Unionpedia): Agonist, Androgen, Antiandrogen, Antidepressant, Antimineralocorticoid, Beta blocker, Bicalutamide, Bioavailability, Biological half-life, Dietary supplement, Enzyme, Eplerenone, Fetus, Finasteride, Glucocorticoid, Hepatotoxicity, Hydroxylation, Immunosuppression, Intravenous therapy, Ketoconazole, Ligand (biochemistry), Potency (pharmacology), Pregnane X receptor, Prodrug, Selective estrogen receptor modulator, Sex steroid, Tamoxifen, Testosterone, Transcription (biology).
Agonist
An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response.
Agonist and CYP3A4 · Agonist and Spironolactone ·
Androgen
An androgen (from Greek andr-, the stem of the word meaning "man") is any natural or synthetic steroid hormone which regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors.
Androgen and CYP3A4 · Androgen and Spironolactone ·
Antiandrogen
Antiandrogens, also known as androgen antagonists or testosterone blockers, are a class of drugs that prevent androgens like testosterone and dihydrotestosterone (DHT) from mediating their biological effects in the body.
Antiandrogen and CYP3A4 · Antiandrogen and Spironolactone ·
Antidepressant
Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive–compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhoea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders.
Antidepressant and CYP3A4 · Antidepressant and Spironolactone ·
Antimineralocorticoid
An antimineralocorticoid, MCRA, or an aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors.
Antimineralocorticoid and CYP3A4 · Antimineralocorticoid and Spironolactone ·
Beta blocker
Beta blockers, also written β-blockers, are a class of medications that are particularly used to manage abnormal heart rhythms, and to protect the heart from a second heart attack (myocardial infarction) after a first heart attack (secondary prevention).
Beta blocker and CYP3A4 · Beta blocker and Spironolactone ·
Bicalutamide
Bicalutamide, sold under the brand name Casodex among others, is an antiandrogen medication that is primarily used to treat prostate cancer.
Bicalutamide and CYP3A4 · Bicalutamide and Spironolactone ·
Bioavailability
In pharmacology, bioavailability (BA or F) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs.
Bioavailability and CYP3A4 · Bioavailability and Spironolactone ·
Biological half-life
The biological half-life of a biological substance is the time it takes for half to be removed by biological processes when the rate of removal is roughly exponential.
Biological half-life and CYP3A4 · Biological half-life and Spironolactone ·
Dietary supplement
A dietary supplement is a manufactured product intended to supplement the diet when taken by mouth as a pill, capsule, tablet, or liquid.
CYP3A4 and Dietary supplement · Dietary supplement and Spironolactone ·
Enzyme
Enzymes are macromolecular biological catalysts.
CYP3A4 and Enzyme · Enzyme and Spironolactone ·
Eplerenone
Eplerenone is a steroidal antimineralocorticoid of the spirolactone group that is used as an adjunct in the management of chronic heart failure.
CYP3A4 and Eplerenone · Eplerenone and Spironolactone ·
Fetus
A fetus is a stage in the prenatal development of viviparous organisms.
CYP3A4 and Fetus · Fetus and Spironolactone ·
Finasteride
Finasteride, sold under the brand names Proscar and Propecia among others, is a medication used mainly to treat an enlarged prostate or scalp hair loss in men.
CYP3A4 and Finasteride · Finasteride and Spironolactone ·
Glucocorticoid
Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones.
CYP3A4 and Glucocorticoid · Glucocorticoid and Spironolactone ·
Hepatotoxicity
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage.
CYP3A4 and Hepatotoxicity · Hepatotoxicity and Spironolactone ·
Hydroxylation
Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound.
CYP3A4 and Hydroxylation · Hydroxylation and Spironolactone ·
Immunosuppression
Immunosuppression is a reduction of the activation or efficacy of the immune system.
CYP3A4 and Immunosuppression · Immunosuppression and Spironolactone ·
Intravenous therapy
Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).
CYP3A4 and Intravenous therapy · Intravenous therapy and Spironolactone ·
Ketoconazole
Ketoconazole is a synthetic imidazole antifungal drug used primarily to treat fungal infections.
CYP3A4 and Ketoconazole · Ketoconazole and Spironolactone ·
Ligand (biochemistry)
In biochemistry and pharmacology, a ligand is a substance that forms a complex with a biomolecule to serve a biological purpose.
CYP3A4 and Ligand (biochemistry) · Ligand (biochemistry) and Spironolactone ·
Potency (pharmacology)
In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.
CYP3A4 and Potency (pharmacology) · Potency (pharmacology) and Spironolactone ·
Pregnane X receptor
In the field of molecular biology, the pregnane X receptor (PXR), also known as the steroid and xenobiotic sensing nuclear receptor (SXR) or nuclear receptor subfamily 1, group I, member 2 (NR1I2) is a protein that in humans is encoded by the NR1I2 (nuclear Receptor subfamily 1, group I, member 2) gene.
CYP3A4 and Pregnane X receptor · Pregnane X receptor and Spironolactone ·
Prodrug
A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug.
CYP3A4 and Prodrug · Prodrug and Spironolactone ·
Selective estrogen receptor modulator
Selective estrogen receptor modulators (SERMs) are a class of drugs that act on the estrogen receptor (ER).
CYP3A4 and Selective estrogen receptor modulator · Selective estrogen receptor modulator and Spironolactone ·
Sex steroid
Sex steroids, also known as gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate androgen or estrogen receptors.
CYP3A4 and Sex steroid · Sex steroid and Spironolactone ·
Tamoxifen
Tamoxifen (TMX), sold under the brand name Nolvadex among others, is a medication that is used to prevent breast cancer in women and treat breast cancer in women and men.
CYP3A4 and Tamoxifen · Spironolactone and Tamoxifen ·
Testosterone
Testosterone is the primary male sex hormone and an anabolic steroid.
CYP3A4 and Testosterone · Spironolactone and Testosterone ·
Transcription (biology)
Transcription is the first step of gene expression, in which a particular segment of DNA is copied into RNA (especially mRNA) by the enzyme RNA polymerase.
CYP3A4 and Transcription (biology) · Spironolactone and Transcription (biology) ·
The list above answers the following questions
- What CYP3A4 and Spironolactone have in common
- What are the similarities between CYP3A4 and Spironolactone
CYP3A4 and Spironolactone Comparison
CYP3A4 has 307 relations, while Spironolactone has 346. As they have in common 29, the Jaccard index is 4.44% = 29 / (307 + 346).
References
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