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Cortisone

Index Cortisone

Cortisone, also known as 17α,21-dihydroxypregn-4-ene-3,11,20-trione, is a pregnane (21-carbon) steroid hormone. [1]

71 relations: Addison's disease, Adrenal cortex, Adrenal gland, Adrenaline, Adrenocorticotropic hormone, Amenorrhea, Anterior pituitary, Anxiety, Atopic dermatitis, Autoimmune disease, Bigger Than Life, Bile acid, Cataract, Central serous retinopathy, Cholesterol, Coccyx, Corticosteroid, Corticotropin-releasing hormone, Cortisol, Cushing's syndrome, Depression (mood), Dermatitis, Dermatology, Diabetes mellitus, Edward Calvin Kendall, Elbow, Enzyme, Fight-or-flight response, Glaucoma, GlaxoSmithKline, Glucocorticoid, Hydrocortisone, Hydrogenation, Hyperglycemia, Hypothalamus, Inflammation, Insulin resistance, Intravenous therapy, James Mason, Jean-Luc Godard, John Cornforth, John F. Kennedy, Joint, Keloid, Kenneth Callow, Knee, Mayo Clinic, Merck & Co., National Institute for Medical Research, Nobel Prize in Physiology or Medicine, ..., Oral administration, Organ transplantation, Osmium tetroxide, Osteoporosis, Percy Lavon Julian, Philip Showalter Hench, Pregnane, Rheumatoid arthritis, Sarcoidosis, Shoulder, Sisal, Steroid, Steroid hormone, Synovial bursa, Tadeusz Reichstein, Tendon, Transdermal, Transplant rejection, Zona fasciculata, Zona reticularis, 11β-Hydroxysteroid dehydrogenase. Expand index (21 more) »

Addison's disease

Addison's disease, also known as primary adrenal insufficiency and hypocortisolism, is a long-term endocrine disorder in which the adrenal glands do not produce enough steroid hormones.

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Adrenal cortex

Situated along the perimeter of the adrenal gland, the adrenal cortex mediates the stress response through the production of mineralocorticoids and glucocorticoids, such as aldosterone and cortisol, respectively.

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Adrenal gland

The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol.

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Adrenaline

Adrenaline, also known as adrenalin or epinephrine, is a hormone, neurotransmitter, and medication.

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Adrenocorticotropic hormone

Adrenocorticotropic hormone (ACTH, also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland.

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Amenorrhea

Amenorrhoea is the absence of a menstrual period in a woman of reproductive age.

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Anterior pituitary

A major organ of the endocrine system, the anterior pituitary (also called the adenohypophysis or pars anterior), is the glandular, anterior lobe that together with the posterior lobe (posterior pituitary, or the neurohypophysis) makes up the pituitary gland (hypophysis).

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Anxiety

Anxiety is an emotion characterized by an unpleasant state of inner turmoil, often accompanied by nervous behaviour such as pacing back and forth, somatic complaints, and rumination.

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Atopic dermatitis

Atopic dermatitis (AD), also known as atopic eczema, is a type of inflammation of the skin (dermatitis).

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Autoimmune disease

An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.

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Bigger Than Life

Bigger Than Life is an American DeLuxe Color CinemaScope film made in 1956 directed by Nicholas Ray and starring James Mason, who also co-wrote and produced the film, about a school teacher and family man whose life spins out of control upon becoming addicted to cortisone.

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Bile acid

Bile acids are steroid acids found predominantly in the bile of mammals and other vertebrates.

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Cataract

A cataract is a clouding of the lens in the eye which leads to a decrease in vision.

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Central serous retinopathy

Central serous retinopathy (CSR), also known as central serous chorioretinopathy (CSC or CSCR), is an eye disease which causes visual impairment, often temporary, usually in one eye.

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Cholesterol

Cholesterol (from the Ancient Greek chole- (bile) and stereos (solid), followed by the chemical suffix -ol for an alcohol) is an organic molecule.

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Coccyx

The coccyx, commonly referred to as the tailbone, is the final segment of the vertebral column in humans and apes, and certain other mammals such as horses.

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Corticosteroid

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.

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Corticotropin-releasing hormone

Corticotropin-releasing hormone (CRH) (also known as corticotropin-releasing factor (CRF) or corticoliberin; corticotropin may also be spelled corticotrophin) is a peptide hormone involved in the stress response.

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Cortisol

Cortisol is a steroid hormone, in the glucocorticoid class of hormones.

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Cushing's syndrome

Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to cortisol.

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Depression (mood)

Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behavior, tendencies, feelings, and sense of well-being.

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Dermatitis

Dermatitis, also known as eczema, is a group of diseases that results in inflammation of the skin.

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Dermatology

Dermatology (from ancient Greek δέρμα, derma which means skin and λογία, logia) is the branch of medicine dealing with the skin, nails, hair and its diseases.

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Diabetes mellitus

Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic disorders in which there are high blood sugar levels over a prolonged period.

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Edward Calvin Kendall

Edward Calvin Kendall (March 8, 1886 – May 4, 1972) was an American chemist.

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Elbow

The elbow is the visible joint between the upper and lower parts of the arm.

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Enzyme

Enzymes are macromolecular biological catalysts.

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Fight-or-flight response

The fight-or-flight response (also called hyperarousal, or the acute stress response) is a physiological reaction that occurs in response to a perceived harmful event, attack, or threat to survival.

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Glaucoma

Glaucoma is a group of eye diseases which result in damage to the optic nerve and vision loss.

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GlaxoSmithKline

GlaxoSmithKline plc (GSK) is a British pharmaceutical company headquartered in Brentford, London.

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Glucocorticoid

Glucocorticoids are a class of corticosteroids, which are a class of steroid hormones.

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Hydrocortisone

Hydrocortisone, sold under a number of brand names, is the name for the hormone cortisol when supplied as a medication.

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Hydrogenation

Hydrogenation – to treat with hydrogen – is a chemical reaction between molecular hydrogen (H2) and another compound or element, usually in the presence of a catalyst such as nickel, palladium or platinum.

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Hyperglycemia

Hyperglycemia, or high blood sugar (also spelled hyperglycaemia or hyperglycæmia) is a condition in which an excessive amount of glucose circulates in the blood plasma.

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Hypothalamus

The hypothalamus(from Greek ὑπό, "under" and θάλαμος, thalamus) is a portion of the brain that contains a number of small nuclei with a variety of functions.

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Inflammation

Inflammation (from inflammatio) is part of the complex biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants, and is a protective response involving immune cells, blood vessels, and molecular mediators.

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Insulin resistance

Insulin resistance (IR) is a pathological condition in which cells fail to respond normally to the hormone insulin.

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Intravenous therapy

Intravenous therapy (IV) is a therapy that delivers liquid substances directly into a vein (intra- + ven- + -ous).

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James Mason

James Neville Mason (15 May 1909 – 27 July 1984) was an English actor.

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Jean-Luc Godard

Jean-Luc Godard (born 3 December 1930) is a French-Swiss film director, screenwriter and film critic.

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John Cornforth

Sir John Warcup Cornforth Jr., AC, CBE, FRS, FAA (7 September 1917 – 8 December 2013) was an AustralianBritish chemist who won the Nobel Prize in Chemistry in 1975 for his work on the stereochemistry of enzyme-catalysed reactions, becoming the only Nobel laureate born in New South Wales.

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John F. Kennedy

John Fitzgerald "Jack" Kennedy (May 29, 1917 – November 22, 1963), commonly referred to by his initials JFK, was an American politician who served as the 35th President of the United States from January 1961 until his assassination in November 1963.

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Joint

A joint or articulation (or articular surface) is the connection made between bones in the body which link the skeletal system into a functional whole.

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Keloid

Keloid, also known as keloid disorder and keloidal scar, is the formation of a type of scar which, depending on its maturity, is composed mainly of either type III (early) or type I (late) collagen.

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Kenneth Callow

Robert Kenneth Callow, FRS (15 February 1901 – 1983) was a British biochemist.

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Knee

The knee joins the thigh with the leg and consists of two joints: one between the femur and tibia (tibiofemoral joint), and one between the femur and patella (patellofemoral joint).

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Mayo Clinic

The Mayo Clinic is a nonprofit academic medical center based in Rochester, Minnesota focused on integrated clinical practice, education, and research.

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Merck & Co.

Merck & Company, Inc., d.b.a. Merck Sharp & Dohme (MSD) outside the United States and Canada, is an American pharmaceutical company and one of the largest pharmaceutical companies in the world.

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National Institute for Medical Research

The National Institute for Medical Research (commonly abbreviated to NIMR), was a medical research institute based in Mill Hill, on the outskirts of London, England.

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Nobel Prize in Physiology or Medicine

The Nobel Prize in Physiology or Medicine (Nobelpriset i fysiologi eller medicin), administered by the Nobel Foundation, is awarded once a year for outstanding discoveries in the fields of life sciences and medicine.

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Oral administration

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Organ transplantation

Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ.

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Osmium tetroxide

Osmium tetroxide (also osmium(VIII) oxide) is the chemical compound with the formula OsO4.

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Osteoporosis

Osteoporosis is a disease where increased bone weakness increases the risk of a broken bone.

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Percy Lavon Julian

Percy Lavon Julian (April 11, 1899 – April 19, 1975) was an African American research chemist and a pioneer in the chemical synthesis of medicinal drugs from plants.

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Philip Showalter Hench

Philip Showalter Hench (February 28, 1896 – March 30, 1965) was an American physician.

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Pregnane

Pregnane is a C21 steroid and, indirectly, a parent of progesterone.

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Rheumatoid arthritis

Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints.

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Sarcoidosis

Sarcoidosis is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomas.

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Shoulder

The human shoulder is made up of three bones: the clavicle (collarbone), the scapula (shoulder blade), and the humerus (upper arm bone) as well as associated muscles, ligaments and tendons.

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Sisal

Sisal, with the botanical name Agave sisalana, is a species of Agave native to southern Mexico but widely cultivated and naturalized in many other countries.

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Steroid

A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration.

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Steroid hormone

A steroid hormone is a steroid that acts as a hormone.

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Synovial bursa

A bursa (plural bursae or bursas) is a small fluid-filled sac lined by synovial membrane with an inner capillary layer of viscous synovial fluid (similar in consistency to that of a raw egg white).

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Tadeusz Reichstein

Tadeusz Reichstein (20 July 1897 – 1 August 1996) was a Polish-Swiss chemist and the Nobel Prize in Physiology or Medicine laureate (1950).

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Tendon

A tendon or sinew is a tough band of fibrous connective tissue that usually connects muscle to bone and is capable of withstanding tension.

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Transdermal

Transdermal is a route of administration wherein active ingredients are delivered across the skin for systemic distribution.

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Transplant rejection

Transplant rejection occurs when transplanted tissue is rejected by the recipient's immune system, which destroys the transplanted tissue.

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Zona fasciculata

The zona fasciculata constitutes the middle and also the widest zone of the adrenal cortex, sitting directly beneath the zona glomerulosa.

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Zona reticularis

The zona reticularis is the innermost layer of the adrenal cortex, lying deep to the zona fasciculata and superficial to the adrenal medulla.

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11β-Hydroxysteroid dehydrogenase

11β-Hydroxysteroid dehydrogenase (HSD-11β or 11β-HSD) is a family of enzymes that catalyze the conversion of inert 11 keto-products (cortisone) to active cortisol, or vice versa, thus regulating the access of glucocorticoids to the steroid receptors: Thus, the two substrates of this enzyme are 11beta-hydroxysteroid and NADP+, whereas its 3 products are 11-oxosteroid, NADPH, and H+.

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Redirects here:

ATC code H02AB10, ATC code S01BA03, ATCvet code QH02AB10, ATCvet code QS01BA03, Cortazone, Cortison, Cortozone.

References

[1] https://en.wikipedia.org/wiki/Cortisone

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